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The map label for this gene is cutL [H]

Identifier: 110679057

GI number: 110679057

Start: 1686067

End: 1688364

Strand: Direct

Name: cutL [H]

Synonym: RD1_1758

Alternate gene names: 110679057

Gene position: 1686067-1688364 (Clockwise)

Preceding gene: 110679053

Following gene: 110679058

Centisome position: 40.79

GC content: 60.14

Gene sequence:

>2298_bases
ATGGAAAAATTTGGCAAATCACAGCCCGTAAAGCGGGTTGAGGATGTTCGTTTTCTCACAGGTGAAGGTCGCTACGTGGA
TGATATCGCGCCTGAGGGGGCGCTTTTTGCCTTTGTGTTTCGCGCGCCTGTGGCCCATGCGGTGATCACCGGTCTGGATG
TGGCGCAGGCGCGCGGCGCGCCGGGCGTGCACGCGGTGCTGACGGCGGATGATCTGAAGGCGGCCGGGATAACCAAGTCG
ATGTCAGCCCAGACGGTCAAGAACCGCGATGGCAGCATGGGCGCGGCCCCCCGCAGACCGATCCTCGCCGAGGAGCGTAT
GCGTTTTGTGGGTGAGCCTGTGGCTTTCATCGTGGCAGAAACGCTTGATCAGGCGCGTGATGCGGCGGAATTGATCGACC
TGTCCTATGAGGAGTTGCCCGCCAAGATGGATATTCAGGCCGGTGGCGCGCCATTGCACGCCGAGGCCCCTGACAATGTG
GCCTTTGACTGGGGCATGGGGGATGAGGCGGCCACGGACGCTGCATTTGCCGCCGCTGCGCGCACCGTATCGCTGGAGGT
GCCGGACAATCGCATCATCGTCAATTCGCTTGAGCCGCGCGGATGTTTCGCGCAGTGGGACGGCGAGCGGGTCCACGTTT
CCGTGGGCGGGCAGGGCGTCTGGGCGCAGAAATCAGAGATCGCGGAATTGCTGAACATCGACGCAGAGCGTGTGCGCGTC
ACCAACCCCGATACAGGCGGTGGTTTCGGGATGAAGGGGTTCCCCTATCCGGAATATGTTCTGGCCGCCCATGCCGCCAA
GGTTGTGGGCAAGCCTGTGCGCTGGATGTCCGAACGCACCGAGGCGATGCTGACCGATAACGCCGGGCGTGACCTGACGA
GCTTTGCCGAATTTGCCTTTGATGAAAACCACAAGATCATCGGATATCGTGTCCACACGCGCTGCAACCTTGGCGCTTAC
AACAGCATGTATGCGCAGTTCATCCAGAGCCAGCTGTTCAGCCGGGTGCTGATGGGGGTCTATGACGTGCAGGCCACATG
GCTGCGGGTCGAGGGGATTTACACCAACACGACCTATGTGGACGCCTATCGCGGCGCAGGGCGACCGGAGGCGATTTACG
TGCTGGAGCGGTTGATTGACCGCGCGGCCCGGACCCTCGGTGTGGACCCGCTGGAATTGCGGCGCATCAACTTCATCAAG
CCGGATCAGTTCCCCTATCAGAACTCCACCGGTGAGGTTTATGACGTCGGCGATTTCGACAAGGTGCTGCGCCGGGCTGA
GCTTGAGGCCGATCTTGCGGGCTTTGCCGCGCGCAAAAAAGCCGATGCGGACCGGGGTCTGCTGCGCGGTCTGGGGCTGT
GTTACTATATTGAAAGTATTTTGGGTGATCCTAGTGAAGGCGCAAAGATCGCGTTCAATGAGGATGGCACCGTGAGCATC
TATGTCGGCACACAAAGCACAGGACAGGGGCATGAAACCGTCTACGCCCAGTTCCTGAGTGATCAGACCGGGATACCGGC
GGATCAGATTTTTGTCGTGCAGGGCGACAGTGATCAGATTGCGCAGGGCGGCGGCACTGGCGGGTCACGCTCCGTTACCG
TGCAGAATACGGCGACGCTGGCCACGGTTGAGGTCATGACCACAGCATTCACAGCGTTTCTGGCCGATGAAATGGGTGTG
CCAGCCTCCGAGATCAGTTTTGACGATGAACGCTTTCGCGCGGATGGCAGCAATATGACGCCGAGCATGTTGGAAGTGGC
GGAGATGGCCCGCGAAAAGGGCCGCGACGATCTGTTGAGCCATGAAGCACGCGCGACCCTGCCTGCGCGCAGTTTCCCCA
ATGGCTGCCATATATCCGAGGTCGTGATTGATCCCGATACCGGCGTTGTCCGCGTGGACCGCTATACGGTGGTGGATGAT
TTTGGCAATCTTATCAACCCGATGCTGGCCGAAGGACAGGTGCATGGCGGTGTCGCTCAAGGTATCGGACAGGCGATCAG
CGAACATGTGGTCTTTGATGAGCAGGGCCAGTTGCTGACCGCGAGTTTCATGGATTACGCCATGCCGCGGGCGGATGGTG
TGCCCAATATTCGCTTTACCTCTGAACCTGTGCCGTCAACGGCGAATATCATGGGGATGAAGGGGTGCGGAGAGGCCGGC
ACGGTTGGGGCCCTCGCGGCTGTGGCGAATGCGGTTCAGGATGCGCTTTGGGAGCATGGCGTGCGGCAGGCGGATATGCC
TTTTACCCCGCTCAAGGTTTGGGAGTTGTTAAACAGTGAGGCTATCGCGGCCGAATAG

Upstream 100 bases:

>100_bases
TTTCTGTGCGATTATGCCGTGACGGGCCACAGCACTGGACATGCGGGTCATCGCCGCTACTGTCCCCACGGACACAGATC
GGTATGCAAGGAGGCATCAC

Downstream 100 bases:

>100_bases
GAAGACGTGGCATTGGCTGCGCCGGGCGATCTGGCGCCGGCCAGCGCGGGATTTCGGGCCCCGGCGGGGGCCGGTCACAC
ATGTTGTCATTCTGGATGGC

Product: dehydrogenase, putative

Products: NA

Alternate protein names: CO dehydrogenase subunit L; CO-DH L [H]

Number of amino acids: Translated: 765; Mature: 765

Protein sequence:

>765_residues
MEKFGKSQPVKRVEDVRFLTGEGRYVDDIAPEGALFAFVFRAPVAHAVITGLDVAQARGAPGVHAVLTADDLKAAGITKS
MSAQTVKNRDGSMGAAPRRPILAEERMRFVGEPVAFIVAETLDQARDAAELIDLSYEELPAKMDIQAGGAPLHAEAPDNV
AFDWGMGDEAATDAAFAAAARTVSLEVPDNRIIVNSLEPRGCFAQWDGERVHVSVGGQGVWAQKSEIAELLNIDAERVRV
TNPDTGGGFGMKGFPYPEYVLAAHAAKVVGKPVRWMSERTEAMLTDNAGRDLTSFAEFAFDENHKIIGYRVHTRCNLGAY
NSMYAQFIQSQLFSRVLMGVYDVQATWLRVEGIYTNTTYVDAYRGAGRPEAIYVLERLIDRAARTLGVDPLELRRINFIK
PDQFPYQNSTGEVYDVGDFDKVLRRAELEADLAGFAARKKADADRGLLRGLGLCYYIESILGDPSEGAKIAFNEDGTVSI
YVGTQSTGQGHETVYAQFLSDQTGIPADQIFVVQGDSDQIAQGGGTGGSRSVTVQNTATLATVEVMTTAFTAFLADEMGV
PASEISFDDERFRADGSNMTPSMLEVAEMAREKGRDDLLSHEARATLPARSFPNGCHISEVVIDPDTGVVRVDRYTVVDD
FGNLINPMLAEGQVHGGVAQGIGQAISEHVVFDEQGQLLTASFMDYAMPRADGVPNIRFTSEPVPSTANIMGMKGCGEAG
TVGALAAVANAVQDALWEHGVRQADMPFTPLKVWELLNSEAIAAE

Sequences:

>Translated_765_residues
MEKFGKSQPVKRVEDVRFLTGEGRYVDDIAPEGALFAFVFRAPVAHAVITGLDVAQARGAPGVHAVLTADDLKAAGITKS
MSAQTVKNRDGSMGAAPRRPILAEERMRFVGEPVAFIVAETLDQARDAAELIDLSYEELPAKMDIQAGGAPLHAEAPDNV
AFDWGMGDEAATDAAFAAAARTVSLEVPDNRIIVNSLEPRGCFAQWDGERVHVSVGGQGVWAQKSEIAELLNIDAERVRV
TNPDTGGGFGMKGFPYPEYVLAAHAAKVVGKPVRWMSERTEAMLTDNAGRDLTSFAEFAFDENHKIIGYRVHTRCNLGAY
NSMYAQFIQSQLFSRVLMGVYDVQATWLRVEGIYTNTTYVDAYRGAGRPEAIYVLERLIDRAARTLGVDPLELRRINFIK
PDQFPYQNSTGEVYDVGDFDKVLRRAELEADLAGFAARKKADADRGLLRGLGLCYYIESILGDPSEGAKIAFNEDGTVSI
YVGTQSTGQGHETVYAQFLSDQTGIPADQIFVVQGDSDQIAQGGGTGGSRSVTVQNTATLATVEVMTTAFTAFLADEMGV
PASEISFDDERFRADGSNMTPSMLEVAEMAREKGRDDLLSHEARATLPARSFPNGCHISEVVIDPDTGVVRVDRYTVVDD
FGNLINPMLAEGQVHGGVAQGIGQAISEHVVFDEQGQLLTASFMDYAMPRADGVPNIRFTSEPVPSTANIMGMKGCGEAG
TVGALAAVANAVQDALWEHGVRQADMPFTPLKVWELLNSEAIAAE
>Mature_765_residues
MEKFGKSQPVKRVEDVRFLTGEGRYVDDIAPEGALFAFVFRAPVAHAVITGLDVAQARGAPGVHAVLTADDLKAAGITKS
MSAQTVKNRDGSMGAAPRRPILAEERMRFVGEPVAFIVAETLDQARDAAELIDLSYEELPAKMDIQAGGAPLHAEAPDNV
AFDWGMGDEAATDAAFAAAARTVSLEVPDNRIIVNSLEPRGCFAQWDGERVHVSVGGQGVWAQKSEIAELLNIDAERVRV
TNPDTGGGFGMKGFPYPEYVLAAHAAKVVGKPVRWMSERTEAMLTDNAGRDLTSFAEFAFDENHKIIGYRVHTRCNLGAY
NSMYAQFIQSQLFSRVLMGVYDVQATWLRVEGIYTNTTYVDAYRGAGRPEAIYVLERLIDRAARTLGVDPLELRRINFIK
PDQFPYQNSTGEVYDVGDFDKVLRRAELEADLAGFAARKKADADRGLLRGLGLCYYIESILGDPSEGAKIAFNEDGTVSI
YVGTQSTGQGHETVYAQFLSDQTGIPADQIFVVQGDSDQIAQGGGTGGSRSVTVQNTATLATVEVMTTAFTAFLADEMGV
PASEISFDDERFRADGSNMTPSMLEVAEMAREKGRDDLLSHEARATLPARSFPNGCHISEVVIDPDTGVVRVDRYTVVDD
FGNLINPMLAEGQVHGGVAQGIGQAISEHVVFDEQGQLLTASFMDYAMPRADGVPNIRFTSEPVPSTANIMGMKGCGEAG
TVGALAAVANAVQDALWEHGVRQADMPFTPLKVWELLNSEAIAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG1529

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI91823271, Length=772, Percent_Identity=24.8704663212435, Blast_Score=149, Evalue=8e-36,
Organism=Homo sapiens, GI71773480, Length=784, Percent_Identity=23.8520408163265, Blast_Score=121, Evalue=3e-27,
Organism=Escherichia coli, GI1789230, Length=779, Percent_Identity=26.0590500641849, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1789246, Length=814, Percent_Identity=24.2014742014742, Blast_Score=192, Evalue=6e-50,
Organism=Escherichia coli, GI1786478, Length=783, Percent_Identity=26.6922094508301, Blast_Score=148, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17539860, Length=784, Percent_Identity=23.0867346938775, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17540638, Length=736, Percent_Identity=23.3695652173913, Blast_Score=129, Evalue=8e-30,
Organism=Drosophila melanogaster, GI24647199, Length=743, Percent_Identity=23.6877523553163, Blast_Score=110, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17737937, Length=698, Percent_Identity=24.2120343839542, Blast_Score=105, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000674
- InterPro:   IPR008274
- InterPro:   IPR012780 [H]

Pfam domain/function: PF01315 Ald_Xan_dh_C; PF02738 Ald_Xan_dh_C2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 82619; Mature: 82619

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKFGKSQPVKRVEDVRFLTGEGRYVDDIAPEGALFAFVFRAPVAHAVITGLDVAQARGA
CCCCCCCCCHHHHHHCEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCC
PGVHAVLTADDLKAAGITKSMSAQTVKNRDGSMGAAPRRPILAEERMRFVGEPVAFIVAE
CCEEEEEEECCCHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
TLDQARDAAELIDLSYEELPAKMDIQAGGAPLHAEAPDNVAFDWGMGDEAATDAAFAAAA
HHHHHHHHHHHHHCCHHHCCCEEEECCCCCCEECCCCCCCEEECCCCCHHHHHHHHHHHE
RTVSLEVPDNRIIVNSLEPRGCFAQWDGERVHVSVGGQGVWAQKSEIAELLNIDAERVRV
EEEEEECCCCEEEEECCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHCCCHHHEEE
TNPDTGGGFGMKGFPYPEYVLAAHAAKVVGKPVRWMSERTEAMLTDNAGRDLTSFAEFAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCHHHHHHHHH
DENHKIIGYRVHTRCNLGAYNSMYAQFIQSQLFSRVLMGVYDVQATWLRVEGIYTNTTYV
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEECCEEE
DAYRGAGRPEAIYVLERLIDRAARTLGVDPLELRRINFIKPDQFPYQNSTGEVYDVGDFD
EHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCCCCCEEECCCHH
KVLRRAELEADLAGFAARKKADADRGLLRGLGLCYYIESILGDPSEGAKIAFNEDGTVSI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
YVGTQSTGQGHETVYAQFLSDQTGIPADQIFVVQGDSDQIAQGGGTGGSRSVTVQNTATL
EEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCCCCCCCCEEEEECCCHH
ATVEVMTTAFTAFLADEMGVPASEISFDDERFRADGSNMTPSMLEVAEMAREKGRDDLLS
HHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
HEARATLPARSFPNGCHISEVVIDPDTGVVRVDRYTVVDDFGNLINPMLAEGQVHGGVAQ
HHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCHHHH
GIGQAISEHVVFDEQGQLLTASFMDYAMPRADGVPNIRFTSEPVPSTANIMGMKGCGEAG
HHHHHHHHHEEECCCCCEEEHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCCCCC
TVGALAAVANAVQDALWEHGVRQADMPFTPLKVWELLNSEAIAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MEKFGKSQPVKRVEDVRFLTGEGRYVDDIAPEGALFAFVFRAPVAHAVITGLDVAQARGA
CCCCCCCCCHHHHHHCEEECCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHCCC
PGVHAVLTADDLKAAGITKSMSAQTVKNRDGSMGAAPRRPILAEERMRFVGEPVAFIVAE
CCEEEEEEECCCHHCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHH
TLDQARDAAELIDLSYEELPAKMDIQAGGAPLHAEAPDNVAFDWGMGDEAATDAAFAAAA
HHHHHHHHHHHHHCCHHHCCCEEEECCCCCCEECCCCCCCEEECCCCCHHHHHHHHHHHE
RTVSLEVPDNRIIVNSLEPRGCFAQWDGERVHVSVGGQGVWAQKSEIAELLNIDAERVRV
EEEEEECCCCEEEEECCCCCCCEEEECCCEEEEEECCCCCCCCHHHHHHHHCCCHHHEEE
TNPDTGGGFGMKGFPYPEYVLAAHAAKVVGKPVRWMSERTEAMLTDNAGRDLTSFAEFAF
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHEEECCCCCCCHHHHHHHHH
DENHKIIGYRVHTRCNLGAYNSMYAQFIQSQLFSRVLMGVYDVQATWLRVEGIYTNTTYV
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEEEEEECCEEE
DAYRGAGRPEAIYVLERLIDRAARTLGVDPLELRRINFIKPDQFPYQNSTGEVYDVGDFD
EHHCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHEECCCCCCCCCCCCCCCCEEECCCHH
KVLRRAELEADLAGFAARKKADADRGLLRGLGLCYYIESILGDPSEGAKIAFNEDGTVSI
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCEEEE
YVGTQSTGQGHETVYAQFLSDQTGIPADQIFVVQGDSDQIAQGGGTGGSRSVTVQNTATL
EEECCCCCCCHHHHHHHHHHCCCCCCCCEEEEEECCCCHHHCCCCCCCCCEEEEECCCHH
ATVEVMTTAFTAFLADEMGVPASEISFDDERFRADGSNMTPSMLEVAEMAREKGRDDLLS
HHHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
HEARATLPARSFPNGCHISEVVIDPDTGVVRVDRYTVVDDFGNLINPMLAEGQVHGGVAQ
HHHHHCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEHHHHHHHHHHHHHCCCCCCHHHH
GIGQAISEHVVFDEQGQLLTASFMDYAMPRADGVPNIRFTSEPVPSTANIMGMKGCGEAG
HHHHHHHHHEEECCCCCEEEHHHHHHHCCCCCCCCCCEECCCCCCCCCCEEECCCCCCCC
TVGALAAVANAVQDALWEHGVRQADMPFTPLKVWELLNSEAIAAE
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]