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The map label for this gene is hisC [H]

Identifier: 110679052

GI number: 110679052

Start: 1679185

End: 1680288

Strand: Reverse

Name: hisC [H]

Synonym: RD1_1752

Alternate gene names: 110679052

Gene position: 1680288-1679185 (Counterclockwise)

Preceding gene: 110679054

Following gene: 110679051

Centisome position: 40.65

GC content: 61.14

Gene sequence:

>1104_bases
ATGATTCGTTTTCGCCTGACCAAAATCGCCGAAACCCTGCCAGCCACTGTTCCCTTTGTCGGCCCCGAAACGCAGGAACG
CGCGCGCGGCATGCGCTTTGATGCGCGGCTTGGAGCCAATGAAAGCGTCTTTGGTCCCTCCCCGAGTGCGGTGCGCGCGA
TGGCGGAAACCCCGCAGTGGATGTATGGCGATCCGGAAAACCATGACCTGCGCAACGCTCTTGCACAGCATCTCGGCACC
CCGCCCGATACGATCATGATCGGTGAAGGGATCGACGGGCTGCTTGGCAATCTGGTGCGGCTTTTTGTGGGCCCGGGCGA
TGCGGTTGTGACCTCGGACGGAGCCTATCCGACGTTCAACTATCATGTCGCGGGTTTTGGCGGGATTGTGCATAAAGTCC
CGTATAATAAGGACTTTGAAGATCTCGCGGCCCTGTTCGAAACGGCCGGTGAGGTGGATGCAAAACTGGTCTACATGTCC
AACCCTGACAACCCCATGGGCACGGTCCACAGCGGCTCCGACATCGCCGCAGCCCTCGATGCGCTGCCCTCCGGCACGCT
GCTCGTGCTGGATGAGGCCTATCTCGAATGCGCCCCGGAAAGCAGCGCGGTGCCGGTCGCCTATGACGATCCGCGCGTGA
TCCGGCTGCGCACCTTCTCCAAAGCGTATGGGCTTGCAGGGGCACGCGTCGGGTATGCGATAGGACATGCGGATGTCATA
TCGGCCTTCAACAAGGTCAGAAACCACTTCGGGATGAACCGCTCCGCACAGGAAGGCGCACTGGCGGCACTGTCCGATCA
GACATGGCTGCGCTCGGTGGTGGCACGTATCACCTCGTCCCGGCTGCGGATCGCCAAGATCGCCACATCCTGCGGATTGA
AGCCAATCAAATCCGCAACAAACTTCGTTGCCATTGATTGCTGCCGCGACAGCGCCTTTGCCAGCCGCGTGTTGGAAGAG
ATGCTGGCGCAGGGCATCTTTGTGCGCATGCCCATGGTCGCCCCCCTCAATCGTTGCGTCAGGGTCAGCTGCGGCACACC
CGCGGACCTTGACCTTCTGGCCGAAGTTCTGCCAGAGGCCCTGCGGCGCGCAGAAAAAGGCTGA

Upstream 100 bases:

>100_bases
TTCTGATAGCTGTAGAAATCCTGACACACATTTCACTGCCTGCGCAACGTCACTGCAAAGCGGGCTTGCTCAAGACGCAT
ACCTTGATTTATCACGCCGC

Downstream 100 bases:

>100_bases
CGTCCACGCGTGCCGCTCTATACTCTTTGAAAAGAGCGGTCAGCGAGGTGTGATATGGAAGGTCACAAGCTTGGGCGGGC
TCCGAATTTCACAGGTGCCT

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 367; Mature: 367

Protein sequence:

>367_residues
MIRFRLTKIAETLPATVPFVGPETQERARGMRFDARLGANESVFGPSPSAVRAMAETPQWMYGDPENHDLRNALAQHLGT
PPDTIMIGEGIDGLLGNLVRLFVGPGDAVVTSDGAYPTFNYHVAGFGGIVHKVPYNKDFEDLAALFETAGEVDAKLVYMS
NPDNPMGTVHSGSDIAAALDALPSGTLLVLDEAYLECAPESSAVPVAYDDPRVIRLRTFSKAYGLAGARVGYAIGHADVI
SAFNKVRNHFGMNRSAQEGALAALSDQTWLRSVVARITSSRLRIAKIATSCGLKPIKSATNFVAIDCCRDSAFASRVLEE
MLAQGIFVRMPMVAPLNRCVRVSCGTPADLDLLAEVLPEALRRAEKG

Sequences:

>Translated_367_residues
MIRFRLTKIAETLPATVPFVGPETQERARGMRFDARLGANESVFGPSPSAVRAMAETPQWMYGDPENHDLRNALAQHLGT
PPDTIMIGEGIDGLLGNLVRLFVGPGDAVVTSDGAYPTFNYHVAGFGGIVHKVPYNKDFEDLAALFETAGEVDAKLVYMS
NPDNPMGTVHSGSDIAAALDALPSGTLLVLDEAYLECAPESSAVPVAYDDPRVIRLRTFSKAYGLAGARVGYAIGHADVI
SAFNKVRNHFGMNRSAQEGALAALSDQTWLRSVVARITSSRLRIAKIATSCGLKPIKSATNFVAIDCCRDSAFASRVLEE
MLAQGIFVRMPMVAPLNRCVRVSCGTPADLDLLAEVLPEALRRAEKG
>Mature_367_residues
MIRFRLTKIAETLPATVPFVGPETQERARGMRFDARLGANESVFGPSPSAVRAMAETPQWMYGDPENHDLRNALAQHLGT
PPDTIMIGEGIDGLLGNLVRLFVGPGDAVVTSDGAYPTFNYHVAGFGGIVHKVPYNKDFEDLAALFETAGEVDAKLVYMS
NPDNPMGTVHSGSDIAAALDALPSGTLLVLDEAYLECAPESSAVPVAYDDPRVIRLRTFSKAYGLAGARVGYAIGHADVI
SAFNKVRNHFGMNRSAQEGALAALSDQTWLRSVVARITSSRLRIAKIATSCGLKPIKSATNFVAIDCCRDSAFASRVLEE
MLAQGIFVRMPMVAPLNRCVRVSCGTPADLDLLAEVLPEALRRAEKG

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=333, Percent_Identity=28.5285285285285, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786816, Length=207, Percent_Identity=28.0193236714976, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322075, Length=359, Percent_Identity=23.6768802228412, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 39393; Mature: 39393

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRFRLTKIAETLPATVPFVGPETQERARGMRFDARLGANESVFGPSPSAVRAMAETPQW
CCEEEHHHHHHHCCCCCCCCCCCHHHHHCCCEEEHHCCCCCCCCCCCHHHHHHHHCCCCC
MYGDPENHDLRNALAQHLGTPPDTIMIGEGIDGLLGNLVRLFVGPGDAVVTSDGAYPTFN
CCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEE
YHVAGFGGIVHKVPYNKDFEDLAALFETAGEVDAKLVYMSNPDNPMGTVHSGSDIAAALD
EEEECCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
ALPSGTLLVLDEAYLECAPESSAVPVAYDDPRVIRLRTFSKAYGLAGARVGYAIGHADVI
HCCCCCEEEEEHHHHHCCCCCCCCCEEECCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHH
SAFNKVRNHFGMNRSAQEGALAALSDQTWLRSVVARITSSRLRIAKIATSCGLKPIKSAT
HHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
NFVAIDCCRDSAFASRVLEEMLAQGIFVRMPMVAPLNRCVRVSCGTPADLDLLAEVLPEA
CEEEEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHEEEECCCCCCHHHHHHHHHHH
LRRAEKG
HHHHCCC
>Mature Secondary Structure
MIRFRLTKIAETLPATVPFVGPETQERARGMRFDARLGANESVFGPSPSAVRAMAETPQW
CCEEEHHHHHHHCCCCCCCCCCCHHHHHCCCEEEHHCCCCCCCCCCCHHHHHHHHCCCCC
MYGDPENHDLRNALAQHLGTPPDTIMIGEGIDGLLGNLVRLFVGPGDAVVTSDGAYPTFN
CCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCEEE
YHVAGFGGIVHKVPYNKDFEDLAALFETAGEVDAKLVYMSNPDNPMGTVHSGSDIAAALD
EEEECCCCHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHH
ALPSGTLLVLDEAYLECAPESSAVPVAYDDPRVIRLRTFSKAYGLAGARVGYAIGHADVI
HCCCCCEEEEEHHHHHCCCCCCCCCEEECCCCEEEEEEHHHHHCCCCHHHHHHHHHHHHH
SAFNKVRNHFGMNRSAQEGALAALSDQTWLRSVVARITSSRLRIAKIATSCGLKPIKSAT
HHHHHHHHHHCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCC
NFVAIDCCRDSAFASRVLEEMLAQGIFVRMPMVAPLNRCVRVSCGTPADLDLLAEVLPEA
CEEEEEECCCHHHHHHHHHHHHHCCEEEECCHHHHHHHHEEEECCCCCCHHHHHHHHHHH
LRRAEKG
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA