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The map label for this gene is pcm [H]

Identifier: 110679041

GI number: 110679041

Start: 1669444

End: 1670097

Strand: Direct

Name: pcm [H]

Synonym: RD1_1741

Alternate gene names: 110679041

Gene position: 1669444-1670097 (Clockwise)

Preceding gene: 110679037

Following gene: 110679042

Centisome position: 40.39

GC content: 59.02

Gene sequence:

>654_bases
ATGGCCGACTTTTTATCACGACGCACGATGATGGTGGACACGCAGGTGCGCCCGTCCGATGTGACAAAGTTCCCAATCAT
AGATGCGATGCTGACCATCCCGCGCGAGGAATTTGTACCTGCTGCACAACGCGAGGCGGCCTATCTGGGCGAAAACCTCC
CAATCGGCGGTCACCGGGTGATCCTTGAACCCAGAACGCTGGCCAAGATGCTGGATGCGCTTGATGTATCTGTGGATGAA
CTGGTTCTGGATGTGGGGTCGGCACTGGGGTATTCGGCAGCGGTCATCGCGCGCATGGCCGAGGCGGTTGTCGCGGTCGA
GGAAGACGAAGCGCTGGCGTCAGAGGCACAGGAAGCCCTGAGTGCTGCGGGTGTCGACAACGTGATCTTGCATGTTGCGC
CACTGGCCGAAGGGGCTGCACAGCACGGTCCCTATGATGTGATGCTGGTGCAGGGCGGCGTGGTTGAATTCCCCCAGACA
TTGGCCGATCAACTCAATGAGGGCGGGCGTGTTGCCTGTATCTTCATGGTGGGCGCTCTGGGCGAGGTGCGCATTGGGCG
CAAGCAAAATGGGAAAATAAGCTGGCGGATGGCGTTTAATGCAGGTGCGCCCGTTCTGCCCGGCTTTGAAAAGGCTGCGG
CATTTCAGTTTTAG

Upstream 100 bases:

>100_bases
AGTGTCACAGCCACATAAAATCCCGTTGTGAAGCGTTGCCGAGCAAACTGAGATGTGCGACATGTTGAAAAGAAACTTCT
AAACGAAAGAGTTTAGCCAA

Downstream 100 bases:

>100_bases
GCGGTGTGGGACAGTAAACAGGCTCTCGGAGAGGCATAATAAATGGCAGTAAGAAGAAAAACCAGAAGCGCTGCGCAAGT
TATGCGCAAAGCGGCATTCT

Product: protein-L-isoaspartate O-methyltransferase, putative

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase 1; Protein L-isoaspartyl methyltransferase 1; Protein-beta-aspartate methyltransferase 1; PIMT 1 [H]

Number of amino acids: Translated: 217; Mature: 216

Protein sequence:

>217_residues
MADFLSRRTMMVDTQVRPSDVTKFPIIDAMLTIPREEFVPAAQREAAYLGENLPIGGHRVILEPRTLAKMLDALDVSVDE
LVLDVGSALGYSAAVIARMAEAVVAVEEDEALASEAQEALSAAGVDNVILHVAPLAEGAAQHGPYDVMLVQGGVVEFPQT
LADQLNEGGRVACIFMVGALGEVRIGRKQNGKISWRMAFNAGAPVLPGFEKAAAFQF

Sequences:

>Translated_217_residues
MADFLSRRTMMVDTQVRPSDVTKFPIIDAMLTIPREEFVPAAQREAAYLGENLPIGGHRVILEPRTLAKMLDALDVSVDE
LVLDVGSALGYSAAVIARMAEAVVAVEEDEALASEAQEALSAAGVDNVILHVAPLAEGAAQHGPYDVMLVQGGVVEFPQT
LADQLNEGGRVACIFMVGALGEVRIGRKQNGKISWRMAFNAGAPVLPGFEKAAAFQF
>Mature_216_residues
ADFLSRRTMMVDTQVRPSDVTKFPIIDAMLTIPREEFVPAAQREAAYLGENLPIGGHRVILEPRTLAKMLDALDVSVDEL
VLDVGSALGYSAAVIARMAEAVVAVEEDEALASEAQEALSAAGVDNVILHVAPLAEGAAQHGPYDVMLVQGGVVEFPQTL
ADQLNEGGRVACIFMVGALGEVRIGRKQNGKISWRMAFNAGAPVLPGFEKAAAFQF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1789100, Length=166, Percent_Identity=29.5180722891566, Blast_Score=87, Evalue=6e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 23118; Mature: 22987

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFLSRRTMMVDTQVRPSDVTKFPIIDAMLTIPREEFVPAAQREAAYLGENLPIGGHRV
CCCHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCCCEE
ILEPRTLAKMLDALDVSVDELVLDVGSALGYSAAVIARMAEAVVAVEEDEALASEAQEAL
EECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
SAAGVDNVILHVAPLAEGAAQHGPYDVMLVQGGVVEFPQTLADQLNEGGRVACIFMVGAL
HHCCCCCEEEEEECHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GEVRIGRKQNGKISWRMAFNAGAPVLPGFEKAAAFQF
CCEEECCCCCCEEEEEEEECCCCCCCCCCHHHHCCCC
>Mature Secondary Structure 
ADFLSRRTMMVDTQVRPSDVTKFPIIDAMLTIPREEFVPAAQREAAYLGENLPIGGHRV
CCHHHCCEEEEECCCCCCCCCCCHHHHHHHHCCHHHCCCCHHHHHHHHCCCCCCCCCEE
ILEPRTLAKMLDALDVSVDELVLDVGSALGYSAAVIARMAEAVVAVEEDEALASEAQEAL
EECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHHHHHH
SAAGVDNVILHVAPLAEGAAQHGPYDVMLVQGGVVEFPQTLADQLNEGGRVACIFMVGAL
HHCCCCCEEEEEECHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCCCCCEEEEEEECCC
GEVRIGRKQNGKISWRMAFNAGAPVLPGFEKAAAFQF
CCEEECCCCCCEEEEEEEECCCCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA