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The map label for this gene is kefC [H]

Identifier: 110678992

GI number: 110678992

Start: 1622598

End: 1624169

Strand: Reverse

Name: kefC [H]

Synonym: RD1_1689

Alternate gene names: 110678992

Gene position: 1624169-1622598 (Counterclockwise)

Preceding gene: 110678993

Following gene: 110678986

Centisome position: 39.3

GC content: 60.75

Gene sequence:

>1572_bases
ATGGTTTTTGAAGTCTTCGCAATCGGCGCTGCATTCATCTTTGGCCTTGCGGCAAAACCGCTGGGGCTGCCACCGCTGGT
GGGTTTTCTGACTGCGGGATTCGTCATCAACGCCGCCGGGCCGCGTGTCGGCATGCCCGATACGACCGGGCCGATCCTTG
AATATATCGCAAACCTCGGTGTCTTGATTCTACTCTTCACGGTGGGCCTCAAGCTGAAGATCAAACAGATCGGCGAGCCG
CATGTTGTCGGTGTGTCCCTGCTGCACTTTGCCTTGTCGGTTGCGCTTTTCACCCCGCTGGCGCGCGCATTTTTCACCGA
TGACTGGACGGTGGCCCTGCTGGTCGGCATCGCACTGGCGTTTTCCTCGACCGTGCTGGCCGCCAAAATGCTGGAATCCA
AACGCGAAATGGGCACATTCCATGGCCGCACCGCCATCGGCATTTTGATCGTGCAGGACATCATCGCGCTTGTTGTGCTG
GCGATCTTTTCGGGCAAGGTGCCGGGACCCTGGGCGCTGCTGATCTTTGCCACGCCCCTGTTGCGCCCGTTTTTGCACAA
GCTGCTCGACTGGGCGGGCCATGACGAGGTGCTGGTGCTCGCAGGCATGGCGCTTGCGCTTGTCATCGGCGGTTACGGGT
TCGAGGTCATCGGGCTAAAGGGCGAGATCGGCGCGCTTGTGATGGGCCTGCTGTTGTCCAATCACCCGCGCGCAAGCGAG
TTGTCAGACGCCCTTTGGTCGCTGAAGGAGGTATTCCTCGTCGGGTTCTTTCTGTCGATTGGCATGTCGGGCTTGCCGGA
CTGGGACGCGCTCGTCTTTGCCATCGTGCTGGGGCTGATGCTGCCGCTCAAGGGGATCCTGTTCTTTTTCCTGCTTGTAG
CCTTCCGCCTGCGGGCCAGAACCGCGTTTCTGTCCGCCCTCTCGCTGACGGTCTACAGCGAATTCGGCCTGATCGTGGCC
ACCGGCATACCGGCAGCGGAACCCTTCGTGGTGCCGCTTGCCATCGCTGTATCGGTATCCTTCCTGATCGCGGCACCAGT
CAACCGGCTGGCCCATCCGCTTTACGAACGCTTTGAAAACCGTTTGCACCGGTTTGAGCGGGTGACGCGCCACCCCGATG
AGCAGCCCGCGGATCTCGGGGATGCGGATGTGATGATTTTCGGCATGGGACGCACCGGCTCCGCCACGTATGAGGTGCTG
ATCCACAACGGGTCCCGCCCGATCGGGCTGGATGCGGACACCTACAAGGCCGCAGCCCACGTCAAAGCCGGGCGCAATGT
GGTATTTGCCGATGCCGAAGACAGCAATTTCTGGAGCAGTGTCGATCTGAGCAAGATCAAATCGGCGGTTCTGGCGATGG
ATGATCTGGAGGCAAAGCTGATCGCGACCCGCACGTTGCGCGCCAAAGGGTTTACAGGTCCGATCGTGACCCATGCCCTG
CATGAGGAGCACATTGATCTGATGAAAGAGGCCGGCGCCAATCAGACCTATCTGACCATGCAGGAAGCGGGGCGCAGCCT
CGCGCACCACGCCGCCGGCACCACGGGCGTCGATCCCTTGTCGGACAAATGA

Upstream 100 bases:

>100_bases
TGCATGACGTGCGGTCGTTCGACATGCTTTGGTGCAACCGCAAGACGCGCACCGGCAAAACCGAACCGGTGGCACAGCAA
CAAAAGAACGACCCGGCATT

Downstream 100 bases:

>100_bases
CCGGCGCGTGCTGCGTCAATGCGGCTTGGGGCGGGGTTGGTTTTCCCGCTCTGCATCAAGTGCCTCTTGCAAAGCATCCG
CATCGTCCGGGTTTTCGGAG

Product: putative potassium efflux transporter

Products: Proton [Cytoplasm]; K (I) [Periplasm] [C]

Alternate protein names: K(+)/H(+) antiporter [H]

Number of amino acids: Translated: 523; Mature: 523

Protein sequence:

>523_residues
MVFEVFAIGAAFIFGLAAKPLGLPPLVGFLTAGFVINAAGPRVGMPDTTGPILEYIANLGVLILLFTVGLKLKIKQIGEP
HVVGVSLLHFALSVALFTPLARAFFTDDWTVALLVGIALAFSSTVLAAKMLESKREMGTFHGRTAIGILIVQDIIALVVL
AIFSGKVPGPWALLIFATPLLRPFLHKLLDWAGHDEVLVLAGMALALVIGGYGFEVIGLKGEIGALVMGLLLSNHPRASE
LSDALWSLKEVFLVGFFLSIGMSGLPDWDALVFAIVLGLMLPLKGILFFFLLVAFRLRARTAFLSALSLTVYSEFGLIVA
TGIPAAEPFVVPLAIAVSVSFLIAAPVNRLAHPLYERFENRLHRFERVTRHPDEQPADLGDADVMIFGMGRTGSATYEVL
IHNGSRPIGLDADTYKAAAHVKAGRNVVFADAEDSNFWSSVDLSKIKSAVLAMDDLEAKLIATRTLRAKGFTGPIVTHAL
HEEHIDLMKEAGANQTYLTMQEAGRSLAHHAAGTTGVDPLSDK

Sequences:

>Translated_523_residues
MVFEVFAIGAAFIFGLAAKPLGLPPLVGFLTAGFVINAAGPRVGMPDTTGPILEYIANLGVLILLFTVGLKLKIKQIGEP
HVVGVSLLHFALSVALFTPLARAFFTDDWTVALLVGIALAFSSTVLAAKMLESKREMGTFHGRTAIGILIVQDIIALVVL
AIFSGKVPGPWALLIFATPLLRPFLHKLLDWAGHDEVLVLAGMALALVIGGYGFEVIGLKGEIGALVMGLLLSNHPRASE
LSDALWSLKEVFLVGFFLSIGMSGLPDWDALVFAIVLGLMLPLKGILFFFLLVAFRLRARTAFLSALSLTVYSEFGLIVA
TGIPAAEPFVVPLAIAVSVSFLIAAPVNRLAHPLYERFENRLHRFERVTRHPDEQPADLGDADVMIFGMGRTGSATYEVL
IHNGSRPIGLDADTYKAAAHVKAGRNVVFADAEDSNFWSSVDLSKIKSAVLAMDDLEAKLIATRTLRAKGFTGPIVTHAL
HEEHIDLMKEAGANQTYLTMQEAGRSLAHHAAGTTGVDPLSDK
>Mature_523_residues
MVFEVFAIGAAFIFGLAAKPLGLPPLVGFLTAGFVINAAGPRVGMPDTTGPILEYIANLGVLILLFTVGLKLKIKQIGEP
HVVGVSLLHFALSVALFTPLARAFFTDDWTVALLVGIALAFSSTVLAAKMLESKREMGTFHGRTAIGILIVQDIIALVVL
AIFSGKVPGPWALLIFATPLLRPFLHKLLDWAGHDEVLVLAGMALALVIGGYGFEVIGLKGEIGALVMGLLLSNHPRASE
LSDALWSLKEVFLVGFFLSIGMSGLPDWDALVFAIVLGLMLPLKGILFFFLLVAFRLRARTAFLSALSLTVYSEFGLIVA
TGIPAAEPFVVPLAIAVSVSFLIAAPVNRLAHPLYERFENRLHRFERVTRHPDEQPADLGDADVMIFGMGRTGSATYEVL
IHNGSRPIGLDADTYKAAAHVKAGRNVVFADAEDSNFWSSVDLSKIKSAVLAMDDLEAKLIATRTLRAKGFTGPIVTHAL
HEEHIDLMKEAGANQTYLTMQEAGRSLAHHAAGTTGVDPLSDK

Specific function: Transport system that facilitates potassium-efflux, possibly by potassium-proton antiport [H]

COG id: COG4651

COG function: function code P; Kef-type K+ transport system, predicted NAD-binding component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RCK N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1786232, Length=551, Percent_Identity=26.3157894736842, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1786685, Length=537, Percent_Identity=24.3947858472998, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789749, Length=466, Percent_Identity=24.6781115879828, Blast_Score=75, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006153
- InterPro:   IPR004771
- InterPro:   IPR006036
- InterPro:   IPR016040
- InterPro:   IPR003148 [H]

Pfam domain/function: PF00999 Na_H_Exchanger; PF02254 TrkA_N [H]

EC number: NA

Molecular weight: Translated: 56044; Mature: 56044

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFEVFAIGAAFIFGLAAKPLGLPPLVGFLTAGFVINAAGPRVGMPDTTGPILEYIANLG
CEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHH
VLILLFTVGLKLKIKQIGEPHVVGVSLLHFALSVALFTPLARAFFTDDWTVALLVGIALA
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FSSTVLAAKMLESKREMGTFHGRTAIGILIVQDIIALVVLAIFSGKVPGPWALLIFATPL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRPFLHKLLDWAGHDEVLVLAGMALALVIGGYGFEVIGLKGEIGALVMGLLLSNHPRASE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCHHH
LSDALWSLKEVFLVGFFLSIGMSGLPDWDALVFAIVLGLMLPLKGILFFFLLVAFRLRAR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLSALSLTVYSEFGLIVATGIPAAEPFVVPLAIAVSVSFLIAAPVNRLAHPLYERFEN
HHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHRFERVTRHPDEQPADLGDADVMIFGMGRTGSATYEVLIHNGSRPIGLDADTYKAAAH
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
VKAGRNVVFADAEDSNFWSSVDLSKIKSAVLAMDDLEAKLIATRTLRAKGFTGPIVTHAL
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HEEHIDLMKEAGANQTYLTMQEAGRSLAHHAAGTTGVDPLSDK
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MVFEVFAIGAAFIFGLAAKPLGLPPLVGFLTAGFVINAAGPRVGMPDTTGPILEYIANLG
CEEEHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHHH
VLILLFTVGLKLKIKQIGEPHVVGVSLLHFALSVALFTPLARAFFTDDWTVALLVGIALA
HHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
FSSTVLAAKMLESKREMGTFHGRTAIGILIVQDIIALVVLAIFSGKVPGPWALLIFATPL
HHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LRPFLHKLLDWAGHDEVLVLAGMALALVIGGYGFEVIGLKGEIGALVMGLLLSNHPRASE
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHCCCCCHHH
LSDALWSLKEVFLVGFFLSIGMSGLPDWDALVFAIVLGLMLPLKGILFFFLLVAFRLRAR
HHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAFLSALSLTVYSEFGLIVATGIPAAEPFVVPLAIAVSVSFLIAAPVNRLAHPLYERFEN
HHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLHRFERVTRHPDEQPADLGDADVMIFGMGRTGSATYEVLIHNGSRPIGLDADTYKAAAH
HHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCHHHHHHHH
VKAGRNVVFADAEDSNFWSSVDLSKIKSAVLAMDDLEAKLIATRTLRAKGFTGPIVTHAL
HHCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
HEEHIDLMKEAGANQTYLTMQEAGRSLAHHAAGTTGVDPLSDK
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Cytoplasm] = Proton [Cytoplasm] + K (I) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA