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The map label for this gene is argD [H]

Identifier: 110678979

GI number: 110678979

Start: 1611561

End: 1612736

Strand: Direct

Name: argD [H]

Synonym: RD1_1676

Alternate gene names: 110678979

Gene position: 1611561-1612736 (Clockwise)

Preceding gene: 110678971

Following gene: 110678980

Centisome position: 38.99

GC content: 62.24

Gene sequence:

>1176_bases
ATGATCCCCACACTACTGCCGACCTATGCCCGTGCCCCCCTGAGCTTTGTAAAAGGCGAAGGTTCCTGGTTGATCGAGGC
GGATGGGCGATGCTTTCTGGATCTGGCGGCGGGGATTGCGGTCACGGCTCTGGGGCACGCGCATCCCAAGCTGGTCAAGG
CGCTCAGCGATCAGGCAGAGGCCCTGTGGCATACCTCGAACCTCTATCAGATCCCGCAACAGCAAGACCTCGCCGACAGG
CTGACTGACCTGACCTTTGCCGATACGGTCTTTTTCACCAACTCGGGCACCGAGGCTTGCGAATTGGCCGTCAAGATGGC
GCGCAAATACTGGAATGACAAAGGCCAGCCGGAGAAATCGCAGATACTGGCCTTTTCAGGGTCGTTTCACGGGCGCTCCG
CCGCCGGGATCGCCGCGGCGGGGTCGGAGAAGATGACCAAGGGCTTTGGCCCGCTCTTGCCCGGTTTCACGCATTTGGAC
TTTGGCGATCACGATGCGCTGAATGCCGCGTTTGACGAGACCACAGCGGCGGTTATCATCGAACCCGTTCAGGGGGAGGG
CGGCATTCGCCCCGTGCCGGATCAATGCCTCAAGGGCTTGCGCGATCTGTGTGACACCCATGGTGTTTTGCTGATCTTTG
ACGAAGTGCAATGCGGCGTGGCGCGCACGGGGCGGCTTTTTGCACATGAATGGGCCGGGGTGACACCGGACATCATGATG
GTCGCCAAAGGCATCGGCGGCGGGTTTCCCATTGGCGCGGTGCTGGCCACCGAAGAGGCCGCCAGCGGCATGACGCTGGG
CACGCATGGGTCGACCTATGGCGGTAATCCGCTCGGTTGCGCGGTGGGTTGCGCGGTGCTGGATCACGTTGCCGATCCTG
CGTTTTTGGCGGATGTGGCGCGCAAGGGCGCCTTGATGCGCCAGCGGCTTGAGGGGCTCGTGGCGGAGCATCCGGAGGTC
TTTGACAGCGTGCGCGGCGCGGGTCTGATGCTGGGCATCAAATGCCGTGCGACCAACTCGGATGTTGTGGCGGCGGGGTA
TGAGGAGTTGATCCTGACGGTCCCTGCCGCTGACAATGTGGTGCGCCTGTTGCCGCCGCTTACAATTTCGGACGATGAAA
TATCGGAGGCCATTGCGCGTCTTGATGCCGCCGCGCGTCGTGTCTCAACGGCCTGA

Upstream 100 bases:

>100_bases
CACTGACACCAACTGAAAACCCTTAAACATTATTGACCTGTGTCCCCGGCTCATGCACGTTCCGCGCTCTGGCCTGAGAT
ACCTACCTGAGGATGATCCG

Downstream 100 bases:

>100_bases
ACCTCGAACCTTTAGTATGCAGGGCGCGACAGTCGCCCGCCTTGAGCAGAGAAAATATAATGAACCACTTTCTCGACATC
CACCTGACGGACCCTGCGGA

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MIPTLLPTYARAPLSFVKGEGSWLIEADGRCFLDLAAGIAVTALGHAHPKLVKALSDQAEALWHTSNLYQIPQQQDLADR
LTDLTFADTVFFTNSGTEACELAVKMARKYWNDKGQPEKSQILAFSGSFHGRSAAGIAAAGSEKMTKGFGPLLPGFTHLD
FGDHDALNAAFDETTAAVIIEPVQGEGGIRPVPDQCLKGLRDLCDTHGVLLIFDEVQCGVARTGRLFAHEWAGVTPDIMM
VAKGIGGGFPIGAVLATEEAASGMTLGTHGSTYGGNPLGCAVGCAVLDHVADPAFLADVARKGALMRQRLEGLVAEHPEV
FDSVRGAGLMLGIKCRATNSDVVAAGYEELILTVPAADNVVRLLPPLTISDDEISEAIARLDAAARRVSTA

Sequences:

>Translated_391_residues
MIPTLLPTYARAPLSFVKGEGSWLIEADGRCFLDLAAGIAVTALGHAHPKLVKALSDQAEALWHTSNLYQIPQQQDLADR
LTDLTFADTVFFTNSGTEACELAVKMARKYWNDKGQPEKSQILAFSGSFHGRSAAGIAAAGSEKMTKGFGPLLPGFTHLD
FGDHDALNAAFDETTAAVIIEPVQGEGGIRPVPDQCLKGLRDLCDTHGVLLIFDEVQCGVARTGRLFAHEWAGVTPDIMM
VAKGIGGGFPIGAVLATEEAASGMTLGTHGSTYGGNPLGCAVGCAVLDHVADPAFLADVARKGALMRQRLEGLVAEHPEV
FDSVRGAGLMLGIKCRATNSDVVAAGYEELILTVPAADNVVRLLPPLTISDDEISEAIARLDAAARRVSTA
>Mature_391_residues
MIPTLLPTYARAPLSFVKGEGSWLIEADGRCFLDLAAGIAVTALGHAHPKLVKALSDQAEALWHTSNLYQIPQQQDLADR
LTDLTFADTVFFTNSGTEACELAVKMARKYWNDKGQPEKSQILAFSGSFHGRSAAGIAAAGSEKMTKGFGPLLPGFTHLD
FGDHDALNAAFDETTAAVIIEPVQGEGGIRPVPDQCLKGLRDLCDTHGVLLIFDEVQCGVARTGRLFAHEWAGVTPDIMM
VAKGIGGGFPIGAVLATEEAASGMTLGTHGSTYGGNPLGCAVGCAVLDHVADPAFLADVARKGALMRQRLEGLVAEHPEV
FDSVRGAGLMLGIKCRATNSDVVAAGYEELILTVPAADNVVRLLPPLTISDDEISEAIARLDAAARRVSTA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=380, Percent_Identity=35.7894736842105, Blast_Score=228, Evalue=5e-60,
Organism=Homo sapiens, GI284507298, Length=294, Percent_Identity=38.4353741496599, Blast_Score=189, Evalue=5e-48,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=30.2272727272727, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI37574042, Length=429, Percent_Identity=27.039627039627, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI24119277, Length=415, Percent_Identity=26.7469879518072, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI226442705, Length=429, Percent_Identity=26.3403263403263, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI226442709, Length=388, Percent_Identity=27.8350515463918, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI188536080, Length=413, Percent_Identity=23.0024213075061, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679950, Length=413, Percent_Identity=23.0024213075061, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679946, Length=413, Percent_Identity=23.0024213075061, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1788044, Length=388, Percent_Identity=44.5876288659794, Blast_Score=330, Evalue=9e-92,
Organism=Escherichia coli, GI1789759, Length=389, Percent_Identity=43.9588688946015, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI145693181, Length=389, Percent_Identity=36.2467866323907, Blast_Score=226, Evalue=2e-60,
Organism=Escherichia coli, GI1789016, Length=401, Percent_Identity=33.6658354114713, Blast_Score=194, Evalue=6e-51,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=35.0746268656716, Blast_Score=182, Evalue=3e-47,
Organism=Escherichia coli, GI1786991, Length=409, Percent_Identity=31.0513447432763, Blast_Score=138, Evalue=8e-34,
Organism=Escherichia coli, GI1786349, Length=298, Percent_Identity=31.8791946308725, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI25144271, Length=377, Percent_Identity=35.0132625994695, Blast_Score=223, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=441, Percent_Identity=29.2517006802721, Blast_Score=168, Evalue=4e-42,
Organism=Caenorhabditis elegans, GI25144274, Length=256, Percent_Identity=35.9375, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI71992977, Length=427, Percent_Identity=28.1030444964871, Blast_Score=128, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI71981843, Length=158, Percent_Identity=33.5443037974684, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17541228, Length=380, Percent_Identity=25.5263157894737, Blast_Score=90, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6324432, Length=398, Percent_Identity=38.6934673366834, Blast_Score=285, Evalue=9e-78,
Organism=Saccharomyces cerevisiae, GI6323470, Length=398, Percent_Identity=32.1608040201005, Blast_Score=202, Evalue=9e-53,
Organism=Saccharomyces cerevisiae, GI6321456, Length=367, Percent_Identity=27.5204359673025, Blast_Score=116, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6324386, Length=300, Percent_Identity=26.3333333333333, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=33.9522546419098, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI161085790, Length=443, Percent_Identity=30.2483069977427, Blast_Score=177, Evalue=7e-45,
Organism=Drosophila melanogaster, GI28574759, Length=378, Percent_Identity=32.8042328042328, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI21356575, Length=416, Percent_Identity=27.4038461538462, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI281366494, Length=383, Percent_Identity=23.7597911227154, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667139, Length=383, Percent_Identity=23.7597911227154, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24667143, Length=383, Percent_Identity=23.7597911227154, Blast_Score=97, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 41173; Mature: 41173

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPTLLPTYARAPLSFVKGEGSWLIEADGRCFLDLAAGIAVTALGHAHPKLVKALSDQAE
CCCCCCCHHHHCCHHEEECCCCEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
ALWHTSNLYQIPQQQDLADRLTDLTFADTVFFTNSGTEACELAVKMARKYWNDKGQPEKS
HHHHCCCCEECCCHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHH
QILAFSGSFHGRSAAGIAAAGSEKMTKGFGPLLPGFTHLDFGDHDALNAAFDETTAAVII
EEEEEECCCCCCCCCCEEECCCHHHHHCCCCCCCCCEECCCCCCHHHHHHHCCCCEEEEE
EPVQGEGGIRPVPDQCLKGLRDLCDTHGVLLIFDEVQCGVARTGRLFAHEWAGVTPDIMM
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCHHHHHHCCCCHHHHH
VAKGIGGGFPIGAVLATEEAASGMTLGTHGSTYGGNPLGCAVGCAVLDHVADPAFLADVA
HHHHCCCCCCHHHEEECHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
RKGALMRQRLEGLVAEHPEVFDSVRGAGLMLGIKCRATNSDVVAAGYEELILTVPAADNV
HHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCC
VRLLPPLTISDDEISEAIARLDAAARRVSTA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIPTLLPTYARAPLSFVKGEGSWLIEADGRCFLDLAAGIAVTALGHAHPKLVKALSDQAE
CCCCCCCHHHHCCHHEEECCCCEEEEECCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHH
ALWHTSNLYQIPQQQDLADRLTDLTFADTVFFTNSGTEACELAVKMARKYWNDKGQPEKS
HHHHCCCCEECCCHHHHHHHHHCCEEEEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHH
QILAFSGSFHGRSAAGIAAAGSEKMTKGFGPLLPGFTHLDFGDHDALNAAFDETTAAVII
EEEEEECCCCCCCCCCEEECCCHHHHHCCCCCCCCCEECCCCCCHHHHHHHCCCCEEEEE
EPVQGEGGIRPVPDQCLKGLRDLCDTHGVLLIFDEVQCGVARTGRLFAHEWAGVTPDIMM
EECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCHHHCCCHHHHHHCCCCHHHHH
VAKGIGGGFPIGAVLATEEAASGMTLGTHGSTYGGNPLGCAVGCAVLDHVADPAFLADVA
HHHHCCCCCCHHHEEECHHHHCCCEECCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHH
RKGALMRQRLEGLVAEHPEVFDSVRGAGLMLGIKCRATNSDVVAAGYEELILTVPAADNV
HHHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEEECCCCCEEECCCEEEEEECCCCCCC
VRLLPPLTISDDEISEAIARLDAAARRVSTA
HHHCCCCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]