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The map label for this gene is ccrA [H]

Identifier: 110678943

GI number: 110678943

Start: 1576775

End: 1578055

Strand: Direct

Name: ccrA [H]

Synonym: RD1_1637

Alternate gene names: 110678943

Gene position: 1576775-1578055 (Clockwise)

Preceding gene: 110678942

Following gene: 110678944

Centisome position: 38.15

GC content: 57.14

Gene sequence:

>1281_bases
ATGGCACTGGATACGACCGTCGCACATTACGAAGCACCCGAAAAAGATCTCTATGAGGTCGGTGAGATGCCCCCCATGGG
CTATGTGCCAAAGCAAATGTATGCTTGGGCCATCCGTCGCGAACGCCATGGCGAGCCTGACAAGGCAATGCTGCAGGAAG
TGGTGGATGTGCCGGAACTCGACAGCCAGGACGTGCTGATATTGGTGATGGCGGCCGGGGTGAATTACAACGGTGTCTGG
GCTGCGCTGGGTAAGCCGATCAGCTTTTTTGACAGCCACGATGAACCGTATCAGATCTGCGGGTCGGATGCGGCCGGGAT
CGTTTGGGCGGTCGGAGATCGTGTGACGCGCTGGAAAGTGGGCGATGAAGTGGTCGTGCATTGCAACCAAGACGATGGCG
ATGACGAGGAATGCAACGGGGGCGATCCGATGTATTCGCCATCGCAGCGTATCTGGGGATATGAAACCGCGGATGGGTCC
TTCGCGCAATTCACACGCGTTCAGAGCCAACAGCTTATGCCCCGCCCCAAACACCTCACCTGGGAAGAGTCTGCGTGCTA
CACGCTGACACTGGCAACGGCGTATCGGATGCTGTTTGGTCATGAGCCGCATGACCTCAAGCCGGGGCAGAACGTGCTGG
TCTGGGGCGCATCGGGCGGGCTTGGATCCTATGCGATCCAGTTGATCAACACGGCTGGTGCCAATGCGATCGGCGTGATT
TCGGATGAAAGCAAACGCCAGTTCGTGATGGACCTCGGTGCCAAAGGCGTTCTGAACCGCAAGGATTTCAACTGCTGGGG
ACAATTGCCCACGGTGAACACGCCTGAATATGCCACATGGTTTACTGAAGCCCGCAAATTCGGCAAGGCGATCTGGGACA
TCACGGGCAAAGGCGTGAATGTCGATATGGTGTTTGAACATCCCGGCGAAAGCACGTTCCCGGTGTCGACCTTCGTCGTT
AAGAAAGGCGGTATGGTCGTCATTTGTGCGGGGACCACGGGTTTCAACCTGACGTTTGACGTGCGCTACATGTGGATGCA
TCAGAAGCGTTTGCAAGGCAGCCACTTCGCCCACCTCAAACAGGCGAGTGCGGCGAACAAGTTGATGCTGGAACGGCGGC
TCGATCCCTGCATGTCCGAAGTCTTCAGCTGGGCTGACCTGCCGCTGGCACATATGAAAATGCTGCGCAATCAGCACAAG
CCGGGTAACATGTCGGTCCTGGTACAAGCGCCGACAACGGGACTGCGTACATTGGAAGACGCTTTGGAGGCGCGCAGTTA
A

Upstream 100 bases:

>100_bases
GAGGTCTCATATGTTGCAATGTTGCGTATGAGAACTTATTCAGAGCGCAGAGCGACGCGATTCTGCGGCGCGGCATGAAT
GAAACAGGCTGGAGACTGCA

Downstream 100 bases:

>100_bases
CCGCAAACCGAGTCGTTTTGAATGCTGAAGCCCGCGAATCACCACAGTGAATCGCGGGTTTTTTACTTCAAGAAACTGAC
GCTGTGCAGGATCAACAGGT

Product: crotonyl-CoA reductase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 425

Protein sequence:

>426_residues
MALDTTVAHYEAPEKDLYEVGEMPPMGYVPKQMYAWAIRRERHGEPDKAMLQEVVDVPELDSQDVLILVMAAGVNYNGVW
AALGKPISFFDSHDEPYQICGSDAAGIVWAVGDRVTRWKVGDEVVVHCNQDDGDDEECNGGDPMYSPSQRIWGYETADGS
FAQFTRVQSQQLMPRPKHLTWEESACYTLTLATAYRMLFGHEPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVI
SDESKRQFVMDLGAKGVLNRKDFNCWGQLPTVNTPEYATWFTEARKFGKAIWDITGKGVNVDMVFEHPGESTFPVSTFVV
KKGGMVVICAGTTGFNLTFDVRYMWMHQKRLQGSHFAHLKQASAANKLMLERRLDPCMSEVFSWADLPLAHMKMLRNQHK
PGNMSVLVQAPTTGLRTLEDALEARS

Sequences:

>Translated_426_residues
MALDTTVAHYEAPEKDLYEVGEMPPMGYVPKQMYAWAIRRERHGEPDKAMLQEVVDVPELDSQDVLILVMAAGVNYNGVW
AALGKPISFFDSHDEPYQICGSDAAGIVWAVGDRVTRWKVGDEVVVHCNQDDGDDEECNGGDPMYSPSQRIWGYETADGS
FAQFTRVQSQQLMPRPKHLTWEESACYTLTLATAYRMLFGHEPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVI
SDESKRQFVMDLGAKGVLNRKDFNCWGQLPTVNTPEYATWFTEARKFGKAIWDITGKGVNVDMVFEHPGESTFPVSTFVV
KKGGMVVICAGTTGFNLTFDVRYMWMHQKRLQGSHFAHLKQASAANKLMLERRLDPCMSEVFSWADLPLAHMKMLRNQHK
PGNMSVLVQAPTTGLRTLEDALEARS
>Mature_425_residues
ALDTTVAHYEAPEKDLYEVGEMPPMGYVPKQMYAWAIRRERHGEPDKAMLQEVVDVPELDSQDVLILVMAAGVNYNGVWA
ALGKPISFFDSHDEPYQICGSDAAGIVWAVGDRVTRWKVGDEVVVHCNQDDGDDEECNGGDPMYSPSQRIWGYETADGSF
AQFTRVQSQQLMPRPKHLTWEESACYTLTLATAYRMLFGHEPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVIS
DESKRQFVMDLGAKGVLNRKDFNCWGQLPTVNTPEYATWFTEARKFGKAIWDITGKGVNVDMVFEHPGESTFPVSTFVVK
KGGMVVICAGTTGFNLTFDVRYMWMHQKRLQGSHFAHLKQASAANKLMLERRLDPCMSEVFSWADLPLAHMKMLRNQHKP
GNMSVLVQAPTTGLRTLEDALEARS

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI194239676, Length=247, Percent_Identity=27.5303643724696, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI194239674, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI13236495, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17507255, Length=384, Percent_Identity=24.21875, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=205, Percent_Identity=27.8048780487805, Blast_Score=69, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=287, Percent_Identity=26.4808362369338, Blast_Score=80, Evalue=8e-16,
Organism=Saccharomyces cerevisiae, GI6319621, Length=217, Percent_Identity=29.9539170506912, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323729, Length=205, Percent_Identity=30.7317073170732, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6324486, Length=365, Percent_Identity=23.5616438356164, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=301, Percent_Identity=23.2558139534884, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: NA

Molecular weight: Translated: 47431; Mature: 47300

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDTTVAHYEAPEKDLYEVGEMPPMGYVPKQMYAWAIRRERHGEPDKAMLQEVVDVPEL
CCCCCCHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
DSQDVLILVMAAGVNYNGVWAALGKPISFFDSHDEPYQICGSDAAGIVWAVGDRVTRWKV
CCCCEEEEEEECCCCCCCEEHHHCCCCHHHCCCCCCCEECCCCCCEEEEEECCCEEEEEC
GDEVVVHCNQDDGDDEECNGGDPMYSPSQRIWGYETADGSFAQFTRVQSQQLMPRPKHLT
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCC
WEESACYTLTLATAYRMLFGHEPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVI
CCCCCEEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEE
SDESKRQFVMDLGAKGVLNRKDFNCWGQLPTVNTPEYATWFTEARKFGKAIWDITGKGVN
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCE
VDMVFEHPGESTFPVSTFVVKKGGMVVICAGTTGFNLTFDVRYMWMHQKRLQGSHFAHLK
EEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEEEEEEEHHHHHCCCHHHHHH
QASAANKLMLERRLDPCMSEVFSWADLPLAHMKMLRNQHKPGNMSVLVQAPTTGLRTLED
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
ALEARS
HHHCCC
>Mature Secondary Structure 
ALDTTVAHYEAPEKDLYEVGEMPPMGYVPKQMYAWAIRRERHGEPDKAMLQEVVDVPEL
CCCCCHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
DSQDVLILVMAAGVNYNGVWAALGKPISFFDSHDEPYQICGSDAAGIVWAVGDRVTRWKV
CCCCEEEEEEECCCCCCCEEHHHCCCCHHHCCCCCCCEECCCCCCEEEEEECCCEEEEEC
GDEVVVHCNQDDGDDEECNGGDPMYSPSQRIWGYETADGSFAQFTRVQSQQLMPRPKHLT
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCCCCCC
WEESACYTLTLATAYRMLFGHEPHDLKPGQNVLVWGASGGLGSYAIQLINTAGANAIGVI
CCCCCEEEEEHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEE
SDESKRQFVMDLGAKGVLNRKDFNCWGQLPTVNTPEYATWFTEARKFGKAIWDITGKGVN
CCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCE
VDMVFEHPGESTFPVSTFVVKKGGMVVICAGTTGFNLTFDVRYMWMHQKRLQGSHFAHLK
EEEEEECCCCCCCCEEEEEEECCCEEEEEECCCCCEEEEEEEEEEEHHHHHCCCHHHHHH
QASAANKLMLERRLDPCMSEVFSWADLPLAHMKMLRNQHKPGNMSVLVQAPTTGLRTLED
HHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
ALEARS
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]