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The map label for this gene is phnN [C]

Identifier: 110678840

GI number: 110678840

Start: 1450893

End: 1452926

Strand: Direct

Name: phnN [C]

Synonym: RD1_1528

Alternate gene names: 110678840

Gene position: 1450893-1452926 (Clockwise)

Preceding gene: 110678839

Following gene: 110678842

Centisome position: 35.1

GC content: 60.37

Gene sequence:

>2034_bases
GTGCCGGGTACGCTGTTTCTCATTGTCGGTCCAAGTGGCGTTGGCAAGGACACCTTGCTGGAGGGCGCGCGCGATCGTCT
GGCAACGAGCCGGTGGTTTTCCTTCCCGCAGCGGGTTGTCACGCGGGCCGCTGATGCGGGCGGGGAGGATTACATTCCCG
TAACCCCGTCCGAATTCGAACAGCAACTGGCCGCCGGGGCGTTCTGGCATCAATGGCACGCGCATGGCCTGTCCTACGGC
ATCCCCATGCAGGTCGCGCGCGATCTGGACAACGGCATCAACGTCGTGCTGAACGCGTCACGCAATGAGATTGGCGCGTT
TCGTGACAAGGCGACGCATGTCGTGACCATTGGAATTTCTGCGCCGCCCGGCATCGTTGAAGAACGCCTTCATGAGCGCG
GGCGCGAGAGCGAAGAAGAAATAAAGCGGCGTCTGGCGCGCCTTGTGGAGCAAGCCCCCCTGACAGGCTATGCGCTGGAA
ATCGTGAATGACAGAACCATCGAGGAAGGCATAACAGCGCTTGTCGACCTGATCGCCGGGGCGTGCGATCTGAATGCAGA
AATCACCCGCTTTCCGGTCACGATCGGGTCAAAACAGGTTTGTCTGGTTCACAAGGGTAATCAGATCGCCAGCCGCGTGC
TGGCGGGGTCGTCGCGGGTCACACTGTCTTTGCGGGGCAAATCCGTCTCTGCGGAACTGGGCGAAACGTGGAGCGATGAA
ATCGTGTCGCAAGACCTCTGTGCGTTGTCCGAGGGCGCGATGGCGGCGCTGGACGCGGTGGAGGGCGATGTCGTCTCAAT
CGAGCGGTCGCCGACGCCCAAAAGCCGGTCCATCTTGCAAAAGAAAGTGCGCGGCGGTGAGTTGTCTCACGCCGAGATGG
AAGCCTTCATCCACGATCTGGTCAACGGGCGGTTCAGTACCTCGGAAATCGCGGGGTTTCTTGTCGCGGCATCGAACAAC
CTGACGATGGACGAAGTGATCTCGCTGACGCAGGTACGTGCCGCCTTCGCGCATCGCCATGATTGGGGCAAGGCGATCGT
CGTCGACAAACACTCCATGGGGGGCGTGCCGGGCAATCGCATCACACCGATCATCATTCCCATTCTGGCAGCCTTTGGCC
TGACCGTGCCCAAGACATCATCGCGGGCCATCACTTCGGCGGCAGGGACGGCGGATATGATGGAAGTGCTTTCGCGCGTT
GATTTGTCCCCGGACGAAATGAAATCGGTCGTGGAACAGACAAATGGCTGCATCGCATGGAACGGCAACTTGACTCATTC
CCCGGTGGATGACGTCATGAATGCGATAAACCGGCCGCTGGGCTTGCAATCCACATTGCTGGATGTGTCGTCGATCATGT
CCAAAAAGCTTGCGGCAGGGTCCACCCATGTGCTGATCGACATGCCGGTGGGGCCAAAAGCCAAGACGCGCACCCAAGGC
GAAGCGGGCGCGTTGAAAAACCTGTTTGAATCGGTGGGGCAGGGCATCGGGCTGAACACAAAGGTGCAGATATCGGATGG
CACAAAACCCATCGGGCGCGGGGTCGGGCCGGTGCTCGAGGCCTTGGATGTCTTGAGTGTATTGCGTGGAGAGGCAGGCG
CGCCGACCGATTTGCTCGATAAATCCATCGGCTATGCGGCGACGATACTGGAATGGTCCGGGGCCGTGTCCCAGGGGCAG
GGCGCACAGGTGACCCGCGATCTGGTGTCCAGCGGAAAGGCCTTCGAAAAGCTGTTTGAGATCAGGGATGCGCAGGGGCG
CCAACACGACCCGCTCCAGCCCGGGCAATTCACCGAAGATATATGCGCCGACAGATCGGGCCGCGTTGAGGCCATCGACA
TACAAGGGATTTCGGAAGTCGCGCGTTTGTCTGGCGCGCCCAAGGACAAGGCCGCCGGCGTGGTTTTGAACGTTCAGGTC
GGGGATCAGATCGCGGAAAAACAGCCGCTGCTCAGGGTCCATTCCTCCAGTCTGCGCGGGATAGAGGAGGCAGTCTGTGC
CGCTCAGGCGCAGAGCGCTTTCAAAATCCTGTAG

Upstream 100 bases:

>100_bases
CCGGCGTGGATTTTGTGTCGGTGGGCCGCATCACGCAGTCAGCGACCTGTGTTGATATCGGCCTCGACGACCTCTGATCT
GGACCAGGAAAGGGTTAATC

Downstream 100 bases:

>100_bases
GTAAAACGCGCGGGCTGCATGACCGTCCGGCGGCGGAATACCCCAAAGAGATCAGACTGGCCTGACCCCAAACCCGCGCA
AATGCAAACGACGCCGCATG

Product: nucleoside phosphorylase

Products: NA

Alternate protein names: TdRPase

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MPGTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFEQQLAAGAFWHQWHAHGLSYG
IPMQVARDLDNGINVVLNASRNEIGAFRDKATHVVTIGISAPPGIVEERLHERGRESEEEIKRRLARLVEQAPLTGYALE
IVNDRTIEEGITALVDLIAGACDLNAEITRFPVTIGSKQVCLVHKGNQIASRVLAGSSRVTLSLRGKSVSAELGETWSDE
IVSQDLCALSEGAMAALDAVEGDVVSIERSPTPKSRSILQKKVRGGELSHAEMEAFIHDLVNGRFSTSEIAGFLVAASNN
LTMDEVISLTQVRAAFAHRHDWGKAIVVDKHSMGGVPGNRITPIIIPILAAFGLTVPKTSSRAITSAAGTADMMEVLSRV
DLSPDEMKSVVEQTNGCIAWNGNLTHSPVDDVMNAINRPLGLQSTLLDVSSIMSKKLAAGSTHVLIDMPVGPKAKTRTQG
EAGALKNLFESVGQGIGLNTKVQISDGTKPIGRGVGPVLEALDVLSVLRGEAGAPTDLLDKSIGYAATILEWSGAVSQGQ
GAQVTRDLVSSGKAFEKLFEIRDAQGRQHDPLQPGQFTEDICADRSGRVEAIDIQGISEVARLSGAPKDKAAGVVLNVQV
GDQIAEKQPLLRVHSSSLRGIEEAVCAAQAQSAFKIL

Sequences:

>Translated_677_residues
MPGTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFEQQLAAGAFWHQWHAHGLSYG
IPMQVARDLDNGINVVLNASRNEIGAFRDKATHVVTIGISAPPGIVEERLHERGRESEEEIKRRLARLVEQAPLTGYALE
IVNDRTIEEGITALVDLIAGACDLNAEITRFPVTIGSKQVCLVHKGNQIASRVLAGSSRVTLSLRGKSVSAELGETWSDE
IVSQDLCALSEGAMAALDAVEGDVVSIERSPTPKSRSILQKKVRGGELSHAEMEAFIHDLVNGRFSTSEIAGFLVAASNN
LTMDEVISLTQVRAAFAHRHDWGKAIVVDKHSMGGVPGNRITPIIIPILAAFGLTVPKTSSRAITSAAGTADMMEVLSRV
DLSPDEMKSVVEQTNGCIAWNGNLTHSPVDDVMNAINRPLGLQSTLLDVSSIMSKKLAAGSTHVLIDMPVGPKAKTRTQG
EAGALKNLFESVGQGIGLNTKVQISDGTKPIGRGVGPVLEALDVLSVLRGEAGAPTDLLDKSIGYAATILEWSGAVSQGQ
GAQVTRDLVSSGKAFEKLFEIRDAQGRQHDPLQPGQFTEDICADRSGRVEAIDIQGISEVARLSGAPKDKAAGVVLNVQV
GDQIAEKQPLLRVHSSSLRGIEEAVCAAQAQSAFKIL
>Mature_676_residues
PGTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFEQQLAAGAFWHQWHAHGLSYGI
PMQVARDLDNGINVVLNASRNEIGAFRDKATHVVTIGISAPPGIVEERLHERGRESEEEIKRRLARLVEQAPLTGYALEI
VNDRTIEEGITALVDLIAGACDLNAEITRFPVTIGSKQVCLVHKGNQIASRVLAGSSRVTLSLRGKSVSAELGETWSDEI
VSQDLCALSEGAMAALDAVEGDVVSIERSPTPKSRSILQKKVRGGELSHAEMEAFIHDLVNGRFSTSEIAGFLVAASNNL
TMDEVISLTQVRAAFAHRHDWGKAIVVDKHSMGGVPGNRITPIIIPILAAFGLTVPKTSSRAITSAAGTADMMEVLSRVD
LSPDEMKSVVEQTNGCIAWNGNLTHSPVDDVMNAINRPLGLQSTLLDVSSIMSKKLAAGSTHVLIDMPVGPKAKTRTQGE
AGALKNLFESVGQGIGLNTKVQISDGTKPIGRGVGPVLEALDVLSVLRGEAGAPTDLLDKSIGYAATILEWSGAVSQGQG
AQVTRDLVSSGKAFEKLFEIRDAQGRQHDPLQPGQFTEDICADRSGRVEAIDIQGISEVARLSGAPKDKAAGVVLNVQVG
DQIAEKQPLLRVHSSSLRGIEEAVCAAQAQSAFKIL

Specific function: Belongs To An Operon Involved In Alkylphosphonate Uptake And C-P Lyase. Exact Function Not Known. [C]

COG id: COG0213

COG function: function code F; Thymidine phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI166158925, Length=418, Percent_Identity=29.6650717703349, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI4503445, Length=418, Percent_Identity=29.6650717703349, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI166158922, Length=418, Percent_Identity=29.6650717703349, Blast_Score=124, Evalue=2e-28,
Organism=Escherichia coli, GI1790532, Length=179, Percent_Identity=33.5195530726257, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790842, Length=406, Percent_Identity=26.1083743842365, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1790080, Length=183, Percent_Identity=31.1475409836066, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): TYPH_ROSDO (Q16A32)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681847.1
- ProteinModelPortal:   Q16A32
- STRING:   Q16A32
- GeneID:   4197184
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1528
- NMPDR:   fig|375451.6.peg.1432
- eggNOG:   COG0213
- HOGENOM:   HBG460532
- OMA:   ACADGRM
- PhylomeDB:   Q16A32
- ProtClustDB:   CLSK956389
- BioCyc:   RDEN375451:RD1_1528-MONOMER
- HAMAP:   MF_00703
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR008144
- InterPro:   IPR008145
- InterPro:   IPR012699
- InterPro:   IPR013102
- InterPro:   IPR000053
- InterPro:   IPR017872
- InterPro:   IPR013466
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- PANTHER:   PTHR10515
- SMART:   SM00072
- SMART:   SM00941
- TIGRFAMs:   TIGR02645
- TIGRFAMs:   TIGR02322

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; PF00625 Guanylate_kin; PF07831 PYNP_C; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3; SSF54680 PYNP_C

EC number: =2.4.2.4

Molecular weight: Translated: 72032; Mature: 71901

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS00647 THYMID_PHOSPHORYLASE; PS50052 GUANYLATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFE
CCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QQLAAGAFWHQWHAHGLSYGIPMQVARDLDNGINVVLNASRNEIGAFRDKATHVVTIGIS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEEEECC
APPGIVEERLHERGRESEEEIKRRLARLVEQAPLTGYALEIVNDRTIEEGITALVDLIAG
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ACDLNAEITRFPVTIGSKQVCLVHKGNQIASRVLAGSSRVTLSLRGKSVSAELGETWSDE
HCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHH
IVSQDLCALSEGAMAALDAVEGDVVSIERSPTPKSRSILQKKVRGGELSHAEMEAFIHDL
HHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VNGRFSTSEIAGFLVAASNNLTMDEVISLTQVRAAFAHRHDWGKAIVVDKHSMGGVPGNR
HCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
ITPIIIPILAAFGLTVPKTSSRAITSAAGTADMMEVLSRVDLSPDEMKSVVEQTNGCIAW
CCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEE
NGNLTHSPVDDVMNAINRPLGLQSTLLDVSSIMSKKLAAGSTHVLIDMPVGPKAKTRTQG
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
EAGALKNLFESVGQGIGLNTKVQISDGTKPIGRGVGPVLEALDVLSVLRGEAGAPTDLLD
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHH
KSIGYAATILEWSGAVSQGQGAQVTRDLVSSGKAFEKLFEIRDAQGRQHDPLQPGQFTED
HHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ICADRSGRVEAIDIQGISEVARLSGAPKDKAAGVVLNVQVGDQIAEKQPLLRVHSSSLRG
HHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHH
IEEAVCAAQAQSAFKIL
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PGTLFLIVGPSGVGKDTLLEGARDRLATSRWFSFPQRVVTRAADAGGEDYIPVTPSEFE
CCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHH
QQLAAGAFWHQWHAHGLSYGIPMQVARDLDNGINVVLNASRNEIGAFRDKATHVVTIGIS
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCHHHHHHHCCCCEEEEEECC
APPGIVEERLHERGRESEEEIKRRLARLVEQAPLTGYALEIVNDRTIEEGITALVDLIAG
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHH
ACDLNAEITRFPVTIGSKQVCLVHKGNQIASRVLAGSSRVTLSLRGKSVSAELGETWSDE
HCCCCCCEEEEEEEECCCEEEEEECCHHHHHHHHCCCCEEEEEECCCCCCHHHCCCHHHH
IVSQDLCALSEGAMAALDAVEGDVVSIERSPTPKSRSILQKKVRGGELSHAEMEAFIHDL
HHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHH
VNGRFSTSEIAGFLVAASNNLTMDEVISLTQVRAAFAHRHDWGKAIVVDKHSMGGVPGNR
HCCCCCHHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCC
ITPIIIPILAAFGLTVPKTSSRAITSAAGTADMMEVLSRVDLSPDEMKSVVEQTNGCIAW
CCHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEE
NGNLTHSPVDDVMNAINRPLGLQSTLLDVSSIMSKKLAAGSTHVLIDMPVGPKAKTRTQG
CCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCC
EAGALKNLFESVGQGIGLNTKVQISDGTKPIGRGVGPVLEALDVLSVLRGEAGAPTDLLD
HHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHCCHHHHHHHHHHHHHHHCCCCCCHHHHH
KSIGYAATILEWSGAVSQGQGAQVTRDLVSSGKAFEKLFEIRDAQGRQHDPLQPGQFTED
HHCCHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
ICADRSGRVEAIDIQGISEVARLSGAPKDKAAGVVLNVQVGDQIAEKQPLLRVHSSSLRG
HHCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCEEEEEECCCHHHHCCCHHHHHHHHHHH
IEEAVCAAQAQSAFKIL
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA