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The map label for this gene is merA [H]

Identifier: 110678777

GI number: 110678777

Start: 1387141

End: 1387872

Strand: Direct

Name: merA [H]

Synonym: RD1_1463

Alternate gene names: 110678777

Gene position: 1387141-1387872 (Clockwise)

Preceding gene: 110678763

Following gene: 110678778

Centisome position: 33.56

GC content: 58.74

Gene sequence:

>732_bases
ATGCTTGAAATGACACAAATCCAAAAATCCGGCTGGACGCGCCGACTGCCGCTGATCCTTATTCTGGCGGTGGCGGCGAT
CGGGGCGTTCACGCTCAAGGATTATCTGTCGTTCGAGGCCTTGCGCGACAATCGAGAGGCGCTGATTGCGGTGCGCGACA
GTCACTTCGCGATAACCGTGCTGGGCTTTGTGCTGACCTATGTCGTGATTGTTGCATTCTCACTGCCCGGCGCATTGATC
GCAACGCTGACGGGCGGCTTTCTGTTCGGCACCTTTGGCGGCTCCGCGCTAAGCGTTACCGCTGCAACGCTGGGGGCGAC
GGTCATTTTTCTGGCCGCGCGCAACGGTTTGGGTGAAAAGCTCAAGGCGCGGATGGATGCAGCCGAGGGCACCGTGGGCA
AGATCAGCAAGGGGCTGGATGAAAATCAGTGGTCGATGCTGTTTTTCATGCGGCTGGTGCCTGTGGTGCCGTTCTTCGTG
GCCAACCTCGTTCCCGCCTTTCTGGCGGTGCCGCTGCATCGCTATGTCATCTCGACCTTTCTGGGGATTATCCCCGGCTC
GCTTGTGTATTCATCGGTGGGTGCGGGGCTGGGGGAGGTGTTCGCCCGAGGCGAGACGCCCAACTTCGGCATCATCTTTG
AACCACATATATTACTGCCGATCCTGGGGTTGAGTGCGCTGTCAGTGCTTCCCGTCCTCATCAAGGCCATCACTGGCAAG
AAAGACCTCTGA

Upstream 100 bases:

>100_bases
CTGTCACGCCGGATCAAGCGCGCGTGAGGGGGCTATCGCCACGCCGGCGCAGGCGTCATGTAAAGTGTCAATTGCAACCG
GGCCGCAAAAGGTGACAGTA

Downstream 100 bases:

>100_bases
CATGAAACGTATCAAAACCGATGTCCTGATCATTGGCGCCGGGTCGGGTGGTTTGTCCGTCGCCGCGGGTGCCGCCCAGA
TGGGGGCAAATGTTGTCCTG

Product: mercuric reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MLEMTQIQKSGWTRRLPLILILAVAAIGAFTLKDYLSFEALRDNREALIAVRDSHFAITVLGFVLTYVVIVAFSLPGALI
ATLTGGFLFGTFGGSALSVTAATLGATVIFLAARNGLGEKLKARMDAAEGTVGKISKGLDENQWSMLFFMRLVPVVPFFV
ANLVPAFLAVPLHRYVISTFLGIIPGSLVYSSVGAGLGEVFARGETPNFGIIFEPHILLPILGLSALSVLPVLIKAITGK
KDL

Sequences:

>Translated_243_residues
MLEMTQIQKSGWTRRLPLILILAVAAIGAFTLKDYLSFEALRDNREALIAVRDSHFAITVLGFVLTYVVIVAFSLPGALI
ATLTGGFLFGTFGGSALSVTAATLGATVIFLAARNGLGEKLKARMDAAEGTVGKISKGLDENQWSMLFFMRLVPVVPFFV
ANLVPAFLAVPLHRYVISTFLGIIPGSLVYSSVGAGLGEVFARGETPNFGIIFEPHILLPILGLSALSVLPVLIKAITGK
KDL
>Mature_243_residues
MLEMTQIQKSGWTRRLPLILILAVAAIGAFTLKDYLSFEALRDNREALIAVRDSHFAITVLGFVLTYVVIVAFSLPGALI
ATLTGGFLFGTFGGSALSVTAATLGATVIFLAARNGLGEKLKARMDAAEGTVGKISKGLDENQWSMLFFMRLVPVVPFFV
ANLVPAFLAVPLHRYVISTFLGIIPGSLVYSSVGAGLGEVFARGETPNFGIIFEPHILLPILGLSALSVLPVLIKAITGK
KDL

Specific function: Unknown

COG id: COG0398

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TVP38/TMEM64 family [H]

Homologues:

Organism=Escherichia coli, GI87081964, Length=182, Percent_Identity=30.2197802197802, Blast_Score=67, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115533785, Length=166, Percent_Identity=32.5301204819277, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17532687, Length=216, Percent_Identity=25, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015414 [H]

Pfam domain/function: PF09335 SNARE_assoc [H]

EC number: NA

Molecular weight: Translated: 25893; Mature: 25893

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEMTQIQKSGWTRRLPLILILAVAAIGAFTLKDYLSFEALRDNREALIAVRDSHFAITV
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHH
LGFVLTYVVIVAFSLPGALIATLTGGFLFGTFGGSALSVTAATLGATVIFLAARNGLGEK
HHHHHHHHHHHHHHCCHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LKARMDAAEGTVGKISKGLDENQWSMLFFMRLVPVVPFFVANLVPAFLAVPLHRYVISTF
HHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIIPGSLVYSSVGAGLGEVFARGETPNFGIIFEPHILLPILGLSALSVLPVLIKAITGK
HHHHCHHHHHHHHCCCHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
KDL
CCC
>Mature Secondary Structure
MLEMTQIQKSGWTRRLPLILILAVAAIGAFTLKDYLSFEALRDNREALIAVRDSHFAITV
CCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCHHHHH
LGFVLTYVVIVAFSLPGALIATLTGGFLFGTFGGSALSVTAATLGATVIFLAARNGLGEK
HHHHHHHHHHHHHHCCHHHHHHHHCCHHEECCCCCHHHHHHHHHHHHHHHHHHCCCCHHH
LKARMDAAEGTVGKISKGLDENQWSMLFFMRLVPVVPFFVANLVPAFLAVPLHRYVISTF
HHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGIIPGSLVYSSVGAGLGEVFARGETPNFGIIFEPHILLPILGLSALSVLPVLIKAITGK
HHHHCHHHHHHHHCCCHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHCCC
KDL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]