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The map label for this gene is hprK [H]

Identifier: 110678699

GI number: 110678699

Start: 1325898

End: 1326314

Strand: Direct

Name: hprK [H]

Synonym: RD1_1379

Alternate gene names: 110678699

Gene position: 1325898-1326314 (Clockwise)

Preceding gene: 110678698

Following gene: 110678700

Centisome position: 32.08

GC content: 57.79

Gene sequence:

>417_bases
ATGCTGCATGCGACTTGTGTGGATTATCACGCCAAAGGGGTCTTGATCACAGGGCGCTCCGGTCAGGGTAAATCCGCGCT
TGCACTGCAGCTTATGGCTCATGGCGCTGTGCTTGTCGCGGACGATCAGACCGAGGTTTGTGCAAAGGACGGCGGGGCAT
TTGCCCGCGCCCCGGAGCCGACCCAGGGCATGATCGAAGCCAGAGGCATCGGCCTGCTGAACGCGCAGACGCTCGAAAAA
ACGAAGGTCGAACTGGTGATCGATCTGGACCGGCAGGAGGCAGAACGGCTCCCACAGCTGCACAGTAGGGATGTTTGTGG
GGTCATGTTGCCCTGTTTGTATCATTTTGATGCTCCCTATTTCCCTGCCAGCATTCTGCAATACCTTAAGGCGGGCAGAA
GAGAGCCGCATGACTGA

Upstream 100 bases:

>100_bases
CCCGACCGAAGCGGATATTACCTCTGAACCACTGGGGGCGCGTTTTGTTGTCGGGCTGCCGATCTAATCGAAGGAGAGAG
TGAGCGAAGTGTCCTGGCAA

Downstream 100 bases:

>100_bases
CACATCAACCACCGCACGTCGCATTGTATTTGTCACCGGACCGTCGGGGGCGGGGCGTTCAAGTGCCCTCAACGTGCTCG
AAGATGCGGGTTTCGAAGTC

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 138; Mature: 138

Protein sequence:

>138_residues
MLHATCVDYHAKGVLITGRSGQGKSALALQLMAHGAVLVADDQTEVCAKDGGAFARAPEPTQGMIEARGIGLLNAQTLEK
TKVELVIDLDRQEAERLPQLHSRDVCGVMLPCLYHFDAPYFPASILQYLKAGRREPHD

Sequences:

>Translated_138_residues
MLHATCVDYHAKGVLITGRSGQGKSALALQLMAHGAVLVADDQTEVCAKDGGAFARAPEPTQGMIEARGIGLLNAQTLEK
TKVELVIDLDRQEAERLPQLHSRDVCGVMLPCLYHFDAPYFPASILQYLKAGRREPHD
>Mature_138_residues
MLHATCVDYHAKGVLITGRSGQGKSALALQLMAHGAVLVADDQTEVCAKDGGAFARAPEPTQGMIEARGIGLLNAQTLEK
TKVELVIDLDRQEAERLPQLHSRDVCGVMLPCLYHFDAPYFPASILQYLKAGRREPHD

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 15008; Mature: 15008

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLHATCVDYHAKGVLITGRSGQGKSALALQLMAHGAVLVADDQTEVCAKDGGAFARAPEP
CCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCCCC
TQGMIEARGIGLLNAQTLEKTKVELVIDLDRQEAERLPQLHSRDVCGVMLPCLYHFDAPY
CCCCHHHCCCCEECCCHHCCCEEEEEEECCHHHHHHCHHHCCCCHHHHHHHHHHHCCCCC
FPASILQYLKAGRREPHD
CHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MLHATCVDYHAKGVLITGRSGQGKSALALQLMAHGAVLVADDQTEVCAKDGGAFARAPEP
CCCCEEECCCCCEEEEECCCCCCCHHHHHHHHHCCEEEEECCCHHHHHCCCCCCCCCCCC
TQGMIEARGIGLLNAQTLEKTKVELVIDLDRQEAERLPQLHSRDVCGVMLPCLYHFDAPY
CCCCHHHCCCCEECCCHHCCCEEEEEEECCHHHHHHCHHHCCCCHHHHHHHHHHHCCCCC
FPASILQYLKAGRREPHD
CHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA