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The map label for this gene is rnhA

Identifier: 110678672

GI number: 110678672

Start: 1302630

End: 1303082

Strand: Reverse

Name: rnhA

Synonym: RD1_1351

Alternate gene names: 110678672

Gene position: 1303082-1302630 (Counterclockwise)

Preceding gene: 110678673

Following gene: 110678671

Centisome position: 31.53

GC content: 61.81

Gene sequence:

>453_bases
ATGCCTGAGTTGTTCGCCTATACGGATGGTGCCTGTTCGGGCAACCCGGGCCCCGGCGGCTGGGGCGTTTTGCTGCAGGC
CAAAGAGGGCGACAGGCTGGTCAAGGAACGCGCGCTCAAGGGCGGTGAGGCACATACCACCAACAACCGGATGGAGCTTT
TGGCCGCCATCAACGCGCTGGAATCCCTCAGCCGCGCCAGCACGATCACCGTCGTGACCGACAGCAACTACGTCAAAAAT
GGCATCACCGGCTGGATTCATGGCTGGAAGCGAAACGGCTGGAAAAATGCCGCCAAGAAACCCGTCGCGAACGCAGAACT
CTGGCAAAGGCTGGATGAGGCCAACGCACGTCACGACGTCACGTGGAAATGGGTCAAGGGGCACGCCGGGCATGCGGAAA
ACGAACGCGCGGACGAATTGGCGCGCGCGGGCATGGCCCCGTTCAAACCATGA

Upstream 100 bases:

>100_bases
GACCTGCTGGCGGCGGCGGGGCTCACGGTATTTGATCGCCGCGAAGGCTGCGACACGGGTCTGGACGGCGTTGATGCCCA
TTGGATTGTACTGGCCGCCC

Downstream 100 bases:

>100_bases
GCGTGATCGGTTTCCTTGACTATGCGAGCGTGTTTATTTTTGCCCTGACCGGTGGGCTGGCCGCCAGCAGGCAGCAGTTG
GACATCGTTGGCTTTGCCTT

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MPELFAYTDGACSGNPGPGGWGVLLQAKEGDRLVKERALKGGEAHTTNNRMELLAAINALESLSRASTITVVTDSNYVKN
GITGWIHGWKRNGWKNAAKKPVANAELWQRLDEANARHDVTWKWVKGHAGHAENERADELARAGMAPFKP

Sequences:

>Translated_150_residues
MPELFAYTDGACSGNPGPGGWGVLLQAKEGDRLVKERALKGGEAHTTNNRMELLAAINALESLSRASTITVVTDSNYVKN
GITGWIHGWKRNGWKNAAKKPVANAELWQRLDEANARHDVTWKWVKGHAGHAENERADELARAGMAPFKP
>Mature_149_residues
PELFAYTDGACSGNPGPGGWGVLLQAKEGDRLVKERALKGGEAHTTNNRMELLAAINALESLSRASTITVVTDSNYVKNG
ITGWIHGWKRNGWKNAAKKPVANAELWQRLDEANARHDVTWKWVKGHAGHAENERADELARAGMAPFKP

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain

Homologues:

Organism=Homo sapiens, GI21359816, Length=150, Percent_Identity=38, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1786408, Length=143, Percent_Identity=55.2447552447552, Blast_Score=170, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI115532542, Length=148, Percent_Identity=38.5135135135135, Blast_Score=89, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45552509, Length=153, Percent_Identity=35.2941176470588, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137476, Length=153, Percent_Identity=35.2941176470588, Blast_Score=84, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH_ROSDO (Q16AK0)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681679.1
- ProteinModelPortal:   Q16AK0
- STRING:   Q16AK0
- GeneID:   4197364
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1351
- NMPDR:   fig|375451.6.peg.1265
- eggNOG:   COG0328
- HOGENOM:   HBG742437
- OMA:   NGWRTAD
- PhylomeDB:   Q16AK0
- ProtClustDB:   PRK00203
- BioCyc:   RDEN375451:RD1_1351-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00042
- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156

Pfam domain/function: PF00075 RnaseH; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 16399; Mature: 16267

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPELFAYTDGACSGNPGPGGWGVLLQAKEGDRLVKERALKGGEAHTTNNRMELLAAINAL
CCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ESLSRASTITVVTDSNYVKNGITGWIHGWKRNGWKNAAKKPVANAELWQRLDEANARHDV
HHHHCCCEEEEEECCCHHHCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCC
TWKWVKGHAGHAENERADELARAGMAPFKP
EEEEECCCCCCCCCHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PELFAYTDGACSGNPGPGGWGVLLQAKEGDRLVKERALKGGEAHTTNNRMELLAAINAL
CCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
ESLSRASTITVVTDSNYVKNGITGWIHGWKRNGWKNAAKKPVANAELWQRLDEANARHDV
HHHHCCCEEEEEECCCHHHCCCCHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHCCCCCCC
TWKWVKGHAGHAENERADELARAGMAPFKP
EEEEECCCCCCCCCHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA