Click here to switch to the map view.

The map label for this gene is mdtA [H]

Identifier: 110678663

GI number: 110678663

Start: 1292751

End: 1293878

Strand: Reverse

Name: mdtA [H]

Synonym: RD1_1342

Alternate gene names: 110678663

Gene position: 1293878-1292751 (Counterclockwise)

Preceding gene: 110678664

Following gene: 110678662

Centisome position: 31.31

GC content: 64.72

Gene sequence:

>1128_bases
ATGACCCACCCCTTATTCCTATTCCGGCTCACCTGCGCGCTGTTTATCGCGATCTGTCTGAGTGTCCCCTCCATGGCCGC
TGCACAAGGCGGGCCGGCTGCCGTGGGCGTCGAAACCGTCGAGGTCAAAACCATCGCCGACACTGTTCCGCTCTTTGCCG
AGGTGGTGACTGCCCGCGAGGGGACGATTGCCAGCCGCATCGCGGGCACGGTCGATGAAATCATGGTGCTTGAGGGCGCA
TCCGTCGATCAGGGCGAGATGCTGGCAACCCTCGACACCGAGCTTCTGGACATTCTGGCCCGACAGGCCCAGGCACGGCT
GGCAGAGGCCCGCGCAGGCATCGTGATCGCGCAGACGCGCGTCAACCGCGCAGCCAATGCTTTGGCGCGGATCGAGGGTC
TGCGCAACACGGCGTCTTTCTCGACCAGCCGTTTTGATGATGCGCAAAGTGACCTGTTTGAGGCCAACGGGCTGCTCGCC
GAAGCAGAGGCGCGCGTCCAGACCGCCGAGGCGACTTTGGCAGAGACCCGGTATCAACTGGACCGCGCGCGCATCACCGC
CCCCTACGCCGGGATCGTGCTGGAAGTGCAGATCAACCCCGGCGAATTCATCGCATCGGGTGCCGCCGTCGTCACGCTGC
TGGATGTTCAGTCCATGGAGATCGAGGCCAGCGTACCATCGAAATACGTCAGCGTTCTGCAACCCGGACAGGCGGTCGCC
GGAAGCACAGAGACCGGCGTGCCGCTGGATCTGAACGTGCGCGTGTTGCTGCCCGTTGAGGATACCGCCACGCGGACGCG
TCCGGTGCGCTTTACGTCGTCTGATCTGGCCTCTCTGGACCGTTTGGCCATCGGCCAGTCCATCACCATCAACATCCCCA
TCAGCGCCCCGCGCGAGGTTCTGTCGGTGCCCAAAGACGCCTTGGTGCAGGCCCGCGGCGGCTGGACGGTCTTCGTGGCG
GCAGACGGAACGGCGCAACCGCGCACCGTGCAGATCGGTGTCGCACTGGGGGATCGCTTTGAGGTGCTGGATGGGTTGAG
CGAGGGCGACGTCGTTGTGACGCGCGGCAATGAACGGCTGCGCCCCGGACAGGAAATCACGCCGATGACCGGCAGCGAGA
AAGGCTAG

Upstream 100 bases:

>100_bases
ACAGTTCTTCGCGCGCGCACGCGCAGGCCCCGCCCTTGGAGGCGTGCAATTTCGAACTAACTGGTTTACCTGTGCAATGA
TTATTTTACAGGGCGCTCCA

Downstream 100 bases:

>100_bases
CCCATGGACCTGATCCGCTACGCAATTGATCGCCCGATTGCCGTGATGGCTGCCGTCATCATGGCCGTTCTGTTCGGCAC
CATCGCCGTCAGCCGCATTC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MTHPLFLFRLTCALFIAICLSVPSMAAAQGGPAAVGVETVEVKTIADTVPLFAEVVTAREGTIASRIAGTVDEIMVLEGA
SVDQGEMLATLDTELLDILARQAQARLAEARAGIVIAQTRVNRAANALARIEGLRNTASFSTSRFDDAQSDLFEANGLLA
EAEARVQTAEATLAETRYQLDRARITAPYAGIVLEVQINPGEFIASGAAVVTLLDVQSMEIEASVPSKYVSVLQPGQAVA
GSTETGVPLDLNVRVLLPVEDTATRTRPVRFTSSDLASLDRLAIGQSITINIPISAPREVLSVPKDALVQARGGWTVFVA
ADGTAQPRTVQIGVALGDRFEVLDGLSEGDVVVTRGNERLRPGQEITPMTGSEKG

Sequences:

>Translated_375_residues
MTHPLFLFRLTCALFIAICLSVPSMAAAQGGPAAVGVETVEVKTIADTVPLFAEVVTAREGTIASRIAGTVDEIMVLEGA
SVDQGEMLATLDTELLDILARQAQARLAEARAGIVIAQTRVNRAANALARIEGLRNTASFSTSRFDDAQSDLFEANGLLA
EAEARVQTAEATLAETRYQLDRARITAPYAGIVLEVQINPGEFIASGAAVVTLLDVQSMEIEASVPSKYVSVLQPGQAVA
GSTETGVPLDLNVRVLLPVEDTATRTRPVRFTSSDLASLDRLAIGQSITINIPISAPREVLSVPKDALVQARGGWTVFVA
ADGTAQPRTVQIGVALGDRFEVLDGLSEGDVVVTRGNERLRPGQEITPMTGSEKG
>Mature_374_residues
THPLFLFRLTCALFIAICLSVPSMAAAQGGPAAVGVETVEVKTIADTVPLFAEVVTAREGTIASRIAGTVDEIMVLEGAS
VDQGEMLATLDTELLDILARQAQARLAEARAGIVIAQTRVNRAANALARIEGLRNTASFSTSRFDDAQSDLFEANGLLAE
AEARVQTAEATLAETRYQLDRARITAPYAGIVLEVQINPGEFIASGAAVVTLLDVQSMEIEASVPSKYVSVLQPGQAVAG
STETGVPLDLNVRVLLPVEDTATRTRPVRFTSSDLASLDRLAIGQSITINIPISAPREVLSVPKDALVQARGGWTVFVAA
DGTAQPRTVQIGVALGDRFEVLDGLSEGDVVVTRGNERLRPGQEITPMTGSEKG

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=318, Percent_Identity=26.7295597484277, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1789929, Length=395, Percent_Identity=24.8101265822785, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39546; Mature: 39414

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPLFLFRLTCALFIAICLSVPSMAAAQGGPAAVGVETVEVKTIADTVPLFAEVVTARE
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCC
GTIASRIAGTVDEIMVLEGASVDQGEMLATLDTELLDILARQAQARLAEARAGIVIAQTR
CCHHHHHHCCHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHH
VNRAANALARIEGLRNTASFSTSRFDDAQSDLFEANGLLAEAEARVQTAEATLAETRYQL
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
DRARITAPYAGIVLEVQINPGEFIASGAAVVTLLDVQSMEIEASVPSKYVSVLQPGQAVA
HHHEEECCCCCEEEEEEECCCHHHHCCCEEEEEEEEECEEEECCCCHHHHHHHCCCCCCC
GSTETGVPLDLNVRVLLPVEDTATRTRPVRFTSSDLASLDRLAIGQSITINIPISAPREV
CCCCCCCEEEECEEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCCHHH
LSVPKDALVQARGGWTVFVAADGTAQPRTVQIGVALGDRFEVLDGLSEGDVVVTRGNERL
HHCCHHHHEEECCCEEEEEEECCCCCCEEEEEEEEECCHHHHHCCCCCCCEEEECCCCCC
RPGQEITPMTGSEKG
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
THPLFLFRLTCALFIAICLSVPSMAAAQGGPAAVGVETVEVKTIADTVPLFAEVVTARE
CCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHCCC
GTIASRIAGTVDEIMVLEGASVDQGEMLATLDTELLDILARQAQARLAEARAGIVIAQTR
CCHHHHHHCCHHHEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHH
VNRAANALARIEGLRNTASFSTSRFDDAQSDLFEANGLLAEAEARVQTAEATLAETRYQL
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHH
DRARITAPYAGIVLEVQINPGEFIASGAAVVTLLDVQSMEIEASVPSKYVSVLQPGQAVA
HHHEEECCCCCEEEEEEECCCHHHHCCCEEEEEEEEECEEEECCCCHHHHHHHCCCCCCC
GSTETGVPLDLNVRVLLPVEDTATRTRPVRFTSSDLASLDRLAIGQSITINIPISAPREV
CCCCCCCEEEECEEEEEECCCCCCCCCCEEECCHHHHHHHHHHCCCEEEEEECCCCCHHH
LSVPKDALVQARGGWTVFVAADGTAQPRTVQIGVALGDRFEVLDGLSEGDVVVTRGNERL
HHCCHHHHEEECCCEEEEEEECCCCCCEEEEEEEEECCHHHHHCCCCCCCEEEECCCCCC
RPGQEITPMTGSEKG
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA