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The map label for this gene is lysK

Identifier: 110678572

GI number: 110678572

Start: 1208693

End: 1210276

Strand: Direct

Name: lysK

Synonym: RD1_1246

Alternate gene names: 110678572

Gene position: 1208693-1210276 (Clockwise)

Preceding gene: 110678570

Following gene: 110678573

Centisome position: 29.24

GC content: 58.33

Gene sequence:

>1584_bases
ATGTCCGACACCCGTACCGCCGCGATGACGAGCAAAGCATGGCCCTTTGAAGAGGCGCGCCGCGTGCTCAAGCGATACGA
AAAGAACCCGCCGGAGAAAGGCTATGTCCTGTTCGAAACGGGCTATGGCCCATCGGGCCTGCCGCATATCGGCACCTTTG
GCGAGGTGGCGCGCACCTCGATGGTGATGCGGGCGTTTCAGGAAATATCGGATATTCCGACCAGGCTGATCTGCTTTTCC
GATGATCTGGACGGGATGCGCAAAGTGCCGGGCAATGTGCCCAATCCCGACGCGCTGACCGAGCATTTGCAGCGCCCGCT
GACCAGCGTGCCGGACCCGTTCGGGACGCATGCCAGTTTTGGCGCGCATAACAACGCCATGCTGCGCCGGTTTCTGGACA
CTTTCGGGTTCGAGTATGAATTCATTTCCGCGACCGAGTTCTATAACACCGGGCAGTTTGATGAGATTCTGCTGCGCGCC
GCCGCGAAATACGATGAAATCATGGCTGTGATGCTGAAATCGCTGCGCGAGGAGCGGCGCCAGACCTATTCGATTTTCCT
GCCGATCCATCCCGAAAGCGGGCGCGTGATGTATGTCCCGATGAAAGAGGTCAACGCGCAGGCGGGCACCATCACCTTTG
ACAGCGAAGATGGTGAAGAGATGACGCTGCCGGTCACCGGTGGTGCCGTCAAATTGCAGTGGAAGCCAGACTTTGGCGCG
CGTTGGGCGGCCCTCGGCGTGGATTTCGAGATGTATGGCAAGGACCATTCCACCAATACGCCGATCTATGACAAGATCTG
CCGTATCCTGGGCCAGCGCCCGCCGGAGCATTTCACCTATGAGTTGTTTCTGGATGAAAACGGGCAAAAAATTTCCAAAT
CCTCCGGCAATGGGGTCAGCATTGACGAATGGCTGACCTATGCCAGCACCGAGAGCCTGTCGTATTTCATGTACCAAAAG
CCGAAGACGGCCAAGCGCATGTATTTCGACGTGATCCCGAAGGCTGTGGACGAATACCATCAGCAATTGCGCGCCTATGC
CGGTCAGGACACAGCGCAGCGGTTGAACAACCCGGTGTGGCATATCCATGGGGGCGATGTGCCGGCGTCGAATATGCTGG
TGCCGTTTTCCATGCTGCTCAATCTGGCGAGCGTGTCCTCCGCTGAGGATAAATCGCAGCTTTGGGGGTTCATCCAGCGC
TATGCGCCTGAAAGCAATCCGGAAAACAATCCGGATATGGACGCAGCGGCAGATTTCGCCGTGCGGTATTTCAACGATTT
CGTGAAGCCGAAAAAGGTCTATCGCGCGGCCAGTGATCTGGAGCGTGAGGCGCTGGAGGACCTGCGCGACCAGCTCAAGG
CCTATGACGGGCCGGTGGATGATGAGGCGTTGCAGTCCATCGTCTATGCCTGCGGGCGCGAGCGGTTTGATCCCTTGCGC
GGATGGTTCACGGCCCTTTATGAGGTGCTGCTGGGCGCGTCGCAGGGGCCGCGTTTTGGTGGCTTCATCGCCCTTTACGG
GGTGCAGGAAACGGTCGCTCTGATTGATGCCGCGCTTGCCGGTGAATTGCTGAGCGACGACTGA

Upstream 100 bases:

>100_bases
AAAAGGTTACAGGCGCAGATTATTGACGCCGCTATGACAAGGCAATAGGGACGGGCGGAACGTCGCGCAAGAGGCGCGGC
ACCCAGAGGTTTGATATATC

Downstream 100 bases:

>100_bases
CACCCTTGCCGGATGGCGCTGGCGGTTTACCCTTGATCTATCGGATCAAGGAGAATGCCCATGCGTGCAGTTGTTCTAGG
CGTTGTGTTCACGGTTCTGG

Product: lysyl-tRNA synthetase

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSDTRTAAMTSKAWPFEEARRVLKRYEKNPPEKGYVLFETGYGPSGLPHIGTFGEVARTSMVMRAFQEISDIPTRLICFS
DDLDGMRKVPGNVPNPDALTEHLQRPLTSVPDPFGTHASFGAHNNAMLRRFLDTFGFEYEFISATEFYNTGQFDEILLRA
AAKYDEIMAVMLKSLREERRQTYSIFLPIHPESGRVMYVPMKEVNAQAGTITFDSEDGEEMTLPVTGGAVKLQWKPDFGA
RWAALGVDFEMYGKDHSTNTPIYDKICRILGQRPPEHFTYELFLDENGQKISKSSGNGVSIDEWLTYASTESLSYFMYQK
PKTAKRMYFDVIPKAVDEYHQQLRAYAGQDTAQRLNNPVWHIHGGDVPASNMLVPFSMLLNLASVSSAEDKSQLWGFIQR
YAPESNPENNPDMDAAADFAVRYFNDFVKPKKVYRAASDLEREALEDLRDQLKAYDGPVDDEALQSIVYACGRERFDPLR
GWFTALYEVLLGASQGPRFGGFIALYGVQETVALIDAALAGELLSDD

Sequences:

>Translated_527_residues
MSDTRTAAMTSKAWPFEEARRVLKRYEKNPPEKGYVLFETGYGPSGLPHIGTFGEVARTSMVMRAFQEISDIPTRLICFS
DDLDGMRKVPGNVPNPDALTEHLQRPLTSVPDPFGTHASFGAHNNAMLRRFLDTFGFEYEFISATEFYNTGQFDEILLRA
AAKYDEIMAVMLKSLREERRQTYSIFLPIHPESGRVMYVPMKEVNAQAGTITFDSEDGEEMTLPVTGGAVKLQWKPDFGA
RWAALGVDFEMYGKDHSTNTPIYDKICRILGQRPPEHFTYELFLDENGQKISKSSGNGVSIDEWLTYASTESLSYFMYQK
PKTAKRMYFDVIPKAVDEYHQQLRAYAGQDTAQRLNNPVWHIHGGDVPASNMLVPFSMLLNLASVSSAEDKSQLWGFIQR
YAPESNPENNPDMDAAADFAVRYFNDFVKPKKVYRAASDLEREALEDLRDQLKAYDGPVDDEALQSIVYACGRERFDPLR
GWFTALYEVLLGASQGPRFGGFIALYGVQETVALIDAALAGELLSDD
>Mature_526_residues
SDTRTAAMTSKAWPFEEARRVLKRYEKNPPEKGYVLFETGYGPSGLPHIGTFGEVARTSMVMRAFQEISDIPTRLICFSD
DLDGMRKVPGNVPNPDALTEHLQRPLTSVPDPFGTHASFGAHNNAMLRRFLDTFGFEYEFISATEFYNTGQFDEILLRAA
AKYDEIMAVMLKSLREERRQTYSIFLPIHPESGRVMYVPMKEVNAQAGTITFDSEDGEEMTLPVTGGAVKLQWKPDFGAR
WAALGVDFEMYGKDHSTNTPIYDKICRILGQRPPEHFTYELFLDENGQKISKSSGNGVSIDEWLTYASTESLSYFMYQKP
KTAKRMYFDVIPKAVDEYHQQLRAYAGQDTAQRLNNPVWHIHGGDVPASNMLVPFSMLLNLASVSSAEDKSQLWGFIQRY
APESNPENNPDMDAAADFAVRYFNDFVKPKKVYRAASDLEREALEDLRDQLKAYDGPVDDEALQSIVYACGRERFDPLRG
WFTALYEVLLGASQGPRFGGFIALYGVQETVALIDAALAGELLSDD

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SYK_ROSDO (Q16AV0)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_681579.1
- STRING:   Q16AV0
- GeneID:   4197453
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_1246
- NMPDR:   fig|375451.6.peg.1163
- eggNOG:   COG1384
- HOGENOM:   HBG294650
- OMA:   SKGNGLT
- ProtClustDB:   PRK00750
- BioCyc:   RDEN375451:RD1_1246-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00177
- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- Gene3D:   G3DSA:1.10.10.350
- TIGRFAMs:   TIGR00467

Pfam domain/function: PF01921 tRNA-synt_1f; SSF48163 tRNA-synt_bind

EC number: =6.1.1.6

Molecular weight: Translated: 59384; Mature: 59253

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 293-293

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDTRTAAMTSKAWPFEEARRVLKRYEKNPPEKGYVLFETGYGPSGLPHIGTFGEVARTS
CCCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
MVMRAFQEISDIPTRLICFSDDLDGMRKVPGNVPNPDALTEHLQRPLTSVPDPFGTHASF
HHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
GAHNNAMLRRFLDTFGFEYEFISATEFYNTGQFDEILLRAAAKYDEIMAVMLKSLREERR
CCCCHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTYSIFLPIHPESGRVMYVPMKEVNAQAGTITFDSEDGEEMTLPVTGGAVKLQWKPDFGA
CEEEEEEEEECCCCCEEEEEHHHCCCCCCEEEECCCCCCEEEEEEECCEEEEEECCCCCC
RWAALGVDFEMYGKDHSTNTPIYDKICRILGQRPPEHFTYELFLDENGQKISKSSGNGVS
CEEEECCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCC
IDEWLTYASTESLSYFMYQKPKTAKRMYFDVIPKAVDEYHQQLRAYAGQDTAQRLNNPVW
HHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEE
HIHGGDVPASNMLVPFSMLLNLASVSSAEDKSQLWGFIQRYAPESNPENNPDMDAAADFA
EEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VRYFNDFVKPKKVYRAASDLEREALEDLRDQLKAYDGPVDDEALQSIVYACGRERFDPLR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHCHHHH
GWFTALYEVLLGASQGPRFGGFIALYGVQETVALIDAALAGELLSDD
HHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SDTRTAAMTSKAWPFEEARRVLKRYEKNPPEKGYVLFETGYGPSGLPHIGTFGEVARTS
CCCHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHH
MVMRAFQEISDIPTRLICFSDDLDGMRKVPGNVPNPDALTEHLQRPLTSVPDPFGTHASF
HHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
GAHNNAMLRRFLDTFGFEYEFISATEFYNTGQFDEILLRAAAKYDEIMAVMLKSLREERR
CCCCHHHHHHHHHHHCCCEEEEEHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QTYSIFLPIHPESGRVMYVPMKEVNAQAGTITFDSEDGEEMTLPVTGGAVKLQWKPDFGA
CEEEEEEEEECCCCCEEEEEHHHCCCCCCEEEECCCCCCEEEEEEECCEEEEEECCCCCC
RWAALGVDFEMYGKDHSTNTPIYDKICRILGQRPPEHFTYELFLDENGQKISKSSGNGVS
CEEEECCCCEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCEECCCCCCCCC
IDEWLTYASTESLSYFMYQKPKTAKRMYFDVIPKAVDEYHQQLRAYAGQDTAQRLNNPVW
HHHHHHHHCCCHHEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEE
HIHGGDVPASNMLVPFSMLLNLASVSSAEDKSQLWGFIQRYAPESNPENNPDMDAAADFA
EEECCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VRYFNDFVKPKKVYRAASDLEREALEDLRDQLKAYDGPVDDEALQSIVYACGRERFDPLR
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCHHHCHHHH
GWFTALYEVLLGASQGPRFGGFIALYGVQETVALIDAALAGELLSDD
HHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA