Click here to switch to the map view.

The map label for this gene is dcp [H]

Identifier: 110678531

GI number: 110678531

Start: 1165211

End: 1167226

Strand: Direct

Name: dcp [H]

Synonym: RD1_1203

Alternate gene names: 110678531

Gene position: 1165211-1167226 (Clockwise)

Preceding gene: 110678530

Following gene: 110678540

Centisome position: 28.19

GC content: 59.62

Gene sequence:

>2016_bases
ATGACCAATCCATTGCTGCAAGACTGGGCGACACCCTTTCAGATCGCACCCTTTGATGTCATATCTGACGCTGATTTCGC
GCCAGCACTGGACACAGCACTTGCGGCGCACCGCAGCGAGATTGACGCCATTGCCACCTGCGACGAAGCGCCAAGTTTTG
CCAATACAATCGAGGCGCTTGAGGCTGCTGGCGCCGACCTCGACAAGGTTCTTTCGGTGTTCTTCACCGTCGCGGGGGCC
GACAGCAACCCGACGCGCGAGGACCTGCAGCGCCAGTTCTCTCCAATACTCGCCGCGCATTTTTCCGAAATTTCCAGCAA
CAAGGCCCTGTTCAGCAGGGTCAACGCATTGTGGGAAACCCGCGAAACGCTGGGCCTTGGGCCTGAACAGGACCGTGTTT
TGATGCTCACCCACCGTGGGTTTGTGCGCGCGGGGGCTGCACTGACCGGGGCGGAAGACGCACGCATGAAGGAAATCAAG
GCACGCCTTGCCGTTCTGGGGACGGAGTTCACGCAAAACCTTTTGGCGGATGAGCGGGCGTGGTTCATGCCGCTTGCCGA
AGACGATCTTGAGGGCTTGCCCGAATTTGTCGTGGACACCGCGCGCGCGGCGGGTGACGAGAAGGGGGCTGATGGCCCGG
TTGTGACCCTTTCGCGGTCGCTCATCGTTCCGTTTTTGCAGTTTTCCCCACGGCGCGATCTAAGGAAAACCGCCTTTGAA
GCCTGGGTCGCGCGGGGTGCAAATGGGGGTCAGACGGATAACCGCGCCATCGCAGCGGAGATCCTGTCCTTGCGCCAAGA
GCGGGCAAAGCTGTTGGGCTATGAGTCTTTTGCGGATTTCAAACTTGAAACCGAAATGGCCAAGACACCCGCTGCCGTGA
GAGATCTGCTGATGTCGGTGTGGGAGCCAGCGCGTGCGCAGGCGGATGCTGACGCTGCGCGTCTCGCCGAGATGATGCGC
AAGGATGGCATCAACGATGATCTGGCCCCTTGGGACTGGCGCTATTACGCTGAAAAACGGCGCGCCGCAGAACACGATCT
GGATGAGGCAGAGCTGAAGCCATATTTCCAACTGGACCGCATGATCGCGGCCAGCTTTGCCTGTGCACAGCGGCTGTTCG
GGTTGCAGTTCAAGCCATTGGACATACCGCTTTACCACCCGGATTGCCGGGCTTGGGAAGTGACGCGCAACGGCGAACAT
ATCGCCGTGTTCATTGGTGACTATTTCGCCCGTGGGTCCAAAAGATCGGGTGCCTGGTGTTCTGCGATGCGTTCGCAGGC
GAAATTCCCCAAGCCGCAGGCACCGATTGTCATCAATGTGTGCAATTTTGCCAAGGGCGACCCGGCGCTGTTGTCTTATG
ATGACGCGCGCACGCTATTTCACGAATTCGGCCATGCGCTGCACCAGATGCTGTCAGATGTGACCTACGAGAGCATTTCT
GGCACGTCCGTTGCGCGCGACTTTGTTGAGCTTCCCAGCCAGCTTTACGAACACTGGCTGGATGTCCCGGAGGTGCTGTC
AGAATTTGCTGTTCATGCAGAGACTGGCGCGCCCATTCCCCCCGACATGCTGCAGAAAGTGCTCGACGCCTCGACGTTTG
ATATGGGGTTCCAGACCGTGGAATATGTGGCCTCGGCCCTCGTCGATCTGGCGTTTCATGACGGCCCGGCACCTGCGGAC
CCGATGGACAAGCAGCGCGAAGTTCTTGATGCTATCGGCATGCCGCCAGCGATTACGATGCGCCACGCCACGCCGCATTT
TGCCCATGTTTTTGCCGGTGATGGGTATTCCAGCGGGTACTACAGCTACATGTGGTCGGAAGTGATGGATGCGGACGCCT
TTGCCGCCTTCGAAGAAGCGGGCGGTGCGTTTGACCCTGAACGTGCCTCGGCACTTGAACGGCACATATTATCCACGGGT
GGCAGTTCAGACGCGGCGGAGCTTTACATCGCCTTCCGCGGGCGGCTGCCGGGGGTGGATGCGCTGCTCAAAGGGCGCGG
GCTGGCCGCTGAGTAG

Upstream 100 bases:

>100_bases
CTGCCCGAGTTGTGGACCACTTCAGGCGAAAGCGTCCTGATCCGCACGGTTGCTCTGGCGTCTGACGCGCCCTAGCTATG
CAAGAACAAGGAGAGCCATG

Downstream 100 bases:

>100_bases
CGCTCAATAGCCTCGCGCACGGTCAACGAGGTTCAAAAAAGCCTCACCTTTTTCACCGCGTACGATGTTGCGGGCAATTT
CTTTTGCGGAAGTCACCGGG

Product: dipeptidyl carboxypeptidase, putative

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MTNPLLQDWATPFQIAPFDVISDADFAPALDTALAAHRSEIDAIATCDEAPSFANTIEALEAAGADLDKVLSVFFTVAGA
DSNPTREDLQRQFSPILAAHFSEISSNKALFSRVNALWETRETLGLGPEQDRVLMLTHRGFVRAGAALTGAEDARMKEIK
ARLAVLGTEFTQNLLADERAWFMPLAEDDLEGLPEFVVDTARAAGDEKGADGPVVTLSRSLIVPFLQFSPRRDLRKTAFE
AWVARGANGGQTDNRAIAAEILSLRQERAKLLGYESFADFKLETEMAKTPAAVRDLLMSVWEPARAQADADAARLAEMMR
KDGINDDLAPWDWRYYAEKRRAAEHDLDEAELKPYFQLDRMIAASFACAQRLFGLQFKPLDIPLYHPDCRAWEVTRNGEH
IAVFIGDYFARGSKRSGAWCSAMRSQAKFPKPQAPIVINVCNFAKGDPALLSYDDARTLFHEFGHALHQMLSDVTYESIS
GTSVARDFVELPSQLYEHWLDVPEVLSEFAVHAETGAPIPPDMLQKVLDASTFDMGFQTVEYVASALVDLAFHDGPAPAD
PMDKQREVLDAIGMPPAITMRHATPHFAHVFAGDGYSSGYYSYMWSEVMDADAFAAFEEAGGAFDPERASALERHILSTG
GSSDAAELYIAFRGRLPGVDALLKGRGLAAE

Sequences:

>Translated_671_residues
MTNPLLQDWATPFQIAPFDVISDADFAPALDTALAAHRSEIDAIATCDEAPSFANTIEALEAAGADLDKVLSVFFTVAGA
DSNPTREDLQRQFSPILAAHFSEISSNKALFSRVNALWETRETLGLGPEQDRVLMLTHRGFVRAGAALTGAEDARMKEIK
ARLAVLGTEFTQNLLADERAWFMPLAEDDLEGLPEFVVDTARAAGDEKGADGPVVTLSRSLIVPFLQFSPRRDLRKTAFE
AWVARGANGGQTDNRAIAAEILSLRQERAKLLGYESFADFKLETEMAKTPAAVRDLLMSVWEPARAQADADAARLAEMMR
KDGINDDLAPWDWRYYAEKRRAAEHDLDEAELKPYFQLDRMIAASFACAQRLFGLQFKPLDIPLYHPDCRAWEVTRNGEH
IAVFIGDYFARGSKRSGAWCSAMRSQAKFPKPQAPIVINVCNFAKGDPALLSYDDARTLFHEFGHALHQMLSDVTYESIS
GTSVARDFVELPSQLYEHWLDVPEVLSEFAVHAETGAPIPPDMLQKVLDASTFDMGFQTVEYVASALVDLAFHDGPAPAD
PMDKQREVLDAIGMPPAITMRHATPHFAHVFAGDGYSSGYYSYMWSEVMDADAFAAFEEAGGAFDPERASALERHILSTG
GSSDAAELYIAFRGRLPGVDALLKGRGLAAE
>Mature_670_residues
TNPLLQDWATPFQIAPFDVISDADFAPALDTALAAHRSEIDAIATCDEAPSFANTIEALEAAGADLDKVLSVFFTVAGAD
SNPTREDLQRQFSPILAAHFSEISSNKALFSRVNALWETRETLGLGPEQDRVLMLTHRGFVRAGAALTGAEDARMKEIKA
RLAVLGTEFTQNLLADERAWFMPLAEDDLEGLPEFVVDTARAAGDEKGADGPVVTLSRSLIVPFLQFSPRRDLRKTAFEA
WVARGANGGQTDNRAIAAEILSLRQERAKLLGYESFADFKLETEMAKTPAAVRDLLMSVWEPARAQADADAARLAEMMRK
DGINDDLAPWDWRYYAEKRRAAEHDLDEAELKPYFQLDRMIAASFACAQRLFGLQFKPLDIPLYHPDCRAWEVTRNGEHI
AVFIGDYFARGSKRSGAWCSAMRSQAKFPKPQAPIVINVCNFAKGDPALLSYDDARTLFHEFGHALHQMLSDVTYESISG
TSVARDFVELPSQLYEHWLDVPEVLSEFAVHAETGAPIPPDMLQKVLDASTFDMGFQTVEYVASALVDLAFHDGPAPADP
MDKQREVLDAIGMPPAITMRHATPHFAHVFAGDGYSSGYYSYMWSEVMDADAFAAFEEAGGAFDPERASALERHILSTGG
SSDAAELYIAFRGRLPGVDALLKGRGLAAE

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=581, Percent_Identity=30.6368330464716, Blast_Score=238, Evalue=2e-62,
Organism=Homo sapiens, GI14149738, Length=584, Percent_Identity=27.2260273972603, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI156105687, Length=581, Percent_Identity=25.1290877796902, Blast_Score=145, Evalue=1e-34,
Organism=Escherichia coli, GI1787819, Length=678, Percent_Identity=38.0530973451327, Blast_Score=427, Evalue=1e-120,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=31.970802919708, Blast_Score=344, Evalue=9e-96,
Organism=Caenorhabditis elegans, GI32565901, Length=557, Percent_Identity=21.0053859964093, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI71999758, Length=214, Percent_Identity=27.1028037383178, Blast_Score=68, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319793, Length=650, Percent_Identity=23.6923076923077, Blast_Score=170, Evalue=7e-43,
Organism=Saccharomyces cerevisiae, GI6322715, Length=590, Percent_Identity=24.0677966101695, Blast_Score=129, Evalue=2e-30,
Organism=Drosophila melanogaster, GI21356111, Length=494, Percent_Identity=26.1133603238866, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI20129717, Length=403, Percent_Identity=26.5508684863524, Blast_Score=135, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 73773; Mature: 73641

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNPLLQDWATPFQIAPFDVISDADFAPALDTALAAHRSEIDAIATCDEAPSFANTIEAL
CCCCCHHHCCCCCEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EAAGADLDKVLSVFFTVAGADSNPTREDLQRQFSPILAAHFSEISSNKALFSRVNALWET
HHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RETLGLGPEQDRVLMLTHRGFVRAGAALTGAEDARMKEIKARLAVLGTEFTQNLLADERA
HHHHCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WFMPLAEDDLEGLPEFVVDTARAAGDEKGADGPVVTLSRSLIVPFLQFSPRRDLRKTAFE
HCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHH
AWVARGANGGQTDNRAIAAEILSLRQERAKLLGYESFADFKLETEMAKTPAAVRDLLMSV
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEHHHHHHCHHHHHHHHHHH
WEPARAQADADAARLAEMMRKDGINDDLAPWDWRYYAEKRRAAEHDLDEAELKPYFQLDR
CCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHH
MIAASFACAQRLFGLQFKPLDIPLYHPDCRAWEVTRNGEHIAVFIGDYFARGSKRSGAWC
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCEEEEEEEHHHHCCCCCCCHHH
SAMRSQAKFPKPQAPIVINVCNFAKGDPALLSYDDARTLFHEFGHALHQMLSDVTYESIS
HHHHHHCCCCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTSVARDFVELPSQLYEHWLDVPEVLSEFAVHAETGAPIPPDMLQKVLDASTFDMGFQTV
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHH
EYVASALVDLAFHDGPAPADPMDKQREVLDAIGMPPAITMRHATPHFAHVFAGDGYSSGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCH
YSYMWSEVMDADAFAAFEEAGGAFDPERASALERHILSTGGSSDAAELYIAFRGRLPGVD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCHH
ALLKGRGLAAE
HHHCCCCCCCC
>Mature Secondary Structure 
TNPLLQDWATPFQIAPFDVISDADFAPALDTALAAHRSEIDAIATCDEAPSFANTIEAL
CCCCHHHCCCCCEECCHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
EAAGADLDKVLSVFFTVAGADSNPTREDLQRQFSPILAAHFSEISSNKALFSRVNALWET
HHCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
RETLGLGPEQDRVLMLTHRGFVRAGAALTGAEDARMKEIKARLAVLGTEFTQNLLADERA
HHHHCCCCCCCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
WFMPLAEDDLEGLPEFVVDTARAAGDEKGADGPVVTLSRSLIVPFLQFSPRRDLRKTAFE
HCCCCCHHHHHCCHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHCCCCHHHHHHHHH
AWVARGANGGQTDNRAIAAEILSLRQERAKLLGYESFADFKLETEMAKTPAAVRDLLMSV
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCEEHHHHHHCHHHHHHHHHHH
WEPARAQADADAARLAEMMRKDGINDDLAPWDWRYYAEKRRAAEHDLDEAELKPYFQLDR
CCHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCHHHHHHH
MIAASFACAQRLFGLQFKPLDIPLYHPDCRAWEVTRNGEHIAVFIGDYFARGSKRSGAWC
HHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEEECCCCEEEEEEEHHHHCCCCCCCHHH
SAMRSQAKFPKPQAPIVINVCNFAKGDPALLSYDDARTLFHEFGHALHQMLSDVTYESIS
HHHHHHCCCCCCCCCEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCC
GTSVARDFVELPSQLYEHWLDVPEVLSEFAVHAETGAPIPPDMLQKVLDASTFDMGFQTV
CHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCHHHHHHHHH
EYVASALVDLAFHDGPAPADPMDKQREVLDAIGMPPAITMRHATPHFAHVFAGDGYSSGY
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCEEEEEECCCCCCCH
YSYMWSEVMDADAFAAFEEAGGAFDPERASALERHILSTGGSSDAAELYIAFRGRLPGVD
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCHH
ALLKGRGLAAE
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]