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The map label for this gene is moeB [H]

Identifier: 110678530

GI number: 110678530

Start: 1164089

End: 1165150

Strand: Direct

Name: moeB [H]

Synonym: RD1_1202

Alternate gene names: 110678530

Gene position: 1164089-1165150 (Clockwise)

Preceding gene: 110678529

Following gene: 110678531

Centisome position: 28.17

GC content: 58.95

Gene sequence:

>1062_bases
ATGCTATTGGTTTTTGGGCTATGCGCCGTTTTATGGGGCATTGGCAGCCTTATGGGCGCGCCGCGTTCCGCCCGCGCAAT
GATGATCGGCATCCTGTATGTCGGCGTTCTGGCCATGCATATCGCGTTGCCGGACCGCCACCCGCTGCGTTTGGCGACGG
GTGAAAGTCCGGCGCTGTGGTTGCTGATCGGTGGTTTCGCGCTGGTGATCTTTTCATACCGTCAGGTGATCACGAGGCTG
CGCACCCGCGCGAAAGCGGTCGAAAAGCAGAGCGACGACGCCCTCGACAGGCCGCTGTTCAATACCAGCGAGTTGAACCG
TTACGCGCGGCATATGGTGCTGCGAGAAATTGGTGGTCCGGGGCAAAAACGGCTGAAAGAAGCAAAGGTTCTGGTCATCG
GCGCGGGTGGGCTTGGTGCGCCCATTTTGCAGTATCTGGCGGCGGCTGGGGTCGGGACGATTGGTGTCATTGATGATGAT
ATGGTCGAAAACGCTAACCTGCAGCGGCAGGTCATTCACCGCGATGCGTCGATTGGCATGGCCAAGGTGTTTTCCGCGCA
GGCCGAAATGACGGCGCAAAACCCCTATGTCGAGGTGCGCCCCTACAACCGCCGCCTGACGGCGGATATCGCGGATGCGT
TGTTTGAGGAGTACGACCTCGTTCTGGATGGGACGGATAATTTCGACACGCGCTATTTGGTGAACGAAACGGCGGTCAAA
GCCGGTATTCCATTGATTTCAGGCGCATTAAGTCAGTGGGAAGGGCAGTTGAGCGTCTTTGACCCCGCCTATGGGGCCCC
GTGTTACCGCTGCGTTTTCAAAAGCGCGCCTGCAGCCGAACTGGCCTCGTCCTGCGCGGAGGCGGGTGTGCTTGGCCCAT
TGCCGGGGGTGATCGGCACAATGATGGCGGTTGAGGCAATCAAGTTGATCACGGATGCAGGCACACCGCTGCGGGGCCAG
ATGCTGATCTATGACGCACTTTATGGTGAAAGCCGAACGATCGCCATCAAACCACGTAGCGACTGCCCGAGTTGTGGACC
ACTTCAGGCGAAAGCGTCCTGA

Upstream 100 bases:

>100_bases
TGGTGGTCGCGCCTGTTGTTCAGGCTAGCTTTGAATTGTCCGATAGCCTGAGCGAAACAGATCGTGGTTCAGGCGGGTTT
GGGTCCACAGGAGGCGATTG

Downstream 100 bases:

>100_bases
TCCGCACGGTTGCTCTGGCGTCTGACGCGCCCTAGCTATGCAAGAACAAGGAGAGCCATGATGACCAATCCATTGCTGCA
AGACTGGGCGACACCCTTTC

Product: molybdopterin biosynthesis protein MoeB, putative

Products: NA

Alternate protein names: Sulfur carrier protein CysO adenylyltransferase; Sulfur carrier protein CysO sulfurtransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MLLVFGLCAVLWGIGSLMGAPRSARAMMIGILYVGVLAMHIALPDRHPLRLATGESPALWLLIGGFALVIFSYRQVITRL
RTRAKAVEKQSDDALDRPLFNTSELNRYARHMVLREIGGPGQKRLKEAKVLVIGAGGLGAPILQYLAAAGVGTIGVIDDD
MVENANLQRQVIHRDASIGMAKVFSAQAEMTAQNPYVEVRPYNRRLTADIADALFEEYDLVLDGTDNFDTRYLVNETAVK
AGIPLISGALSQWEGQLSVFDPAYGAPCYRCVFKSAPAAELASSCAEAGVLGPLPGVIGTMMAVEAIKLITDAGTPLRGQ
MLIYDALYGESRTIAIKPRSDCPSCGPLQAKAS

Sequences:

>Translated_353_residues
MLLVFGLCAVLWGIGSLMGAPRSARAMMIGILYVGVLAMHIALPDRHPLRLATGESPALWLLIGGFALVIFSYRQVITRL
RTRAKAVEKQSDDALDRPLFNTSELNRYARHMVLREIGGPGQKRLKEAKVLVIGAGGLGAPILQYLAAAGVGTIGVIDDD
MVENANLQRQVIHRDASIGMAKVFSAQAEMTAQNPYVEVRPYNRRLTADIADALFEEYDLVLDGTDNFDTRYLVNETAVK
AGIPLISGALSQWEGQLSVFDPAYGAPCYRCVFKSAPAAELASSCAEAGVLGPLPGVIGTMMAVEAIKLITDAGTPLRGQ
MLIYDALYGESRTIAIKPRSDCPSCGPLQAKAS
>Mature_353_residues
MLLVFGLCAVLWGIGSLMGAPRSARAMMIGILYVGVLAMHIALPDRHPLRLATGESPALWLLIGGFALVIFSYRQVITRL
RTRAKAVEKQSDDALDRPLFNTSELNRYARHMVLREIGGPGQKRLKEAKVLVIGAGGLGAPILQYLAAAGVGTIGVIDDD
MVENANLQRQVIHRDASIGMAKVFSAQAEMTAQNPYVEVRPYNRRLTADIADALFEEYDLVLDGTDNFDTRYLVNETAVK
AGIPLISGALSQWEGQLSVFDPAYGAPCYRCVFKSAPAAELASSCAEAGVLGPLPGVIGTMMAVEAIKLITDAGTPLRGQ
MLIYDALYGESRTIAIKPRSDCPSCGPLQAKAS

Specific function: Catalyzes the conversion of the sulfur carrier protein CysO to CysO-thiocarboxylate. The reaction is thought to proceed in two steps:first, ATP-dependent activation of CysO as acyl- adenylate (CysO-COOAMP), followed by sulfur transfer to give CysO- thioca

COG id: COG0476

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=248, Percent_Identity=45.9677419354839, Blast_Score=194, Evalue=9e-50,
Organism=Homo sapiens, GI38045944, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI38045942, Length=168, Percent_Identity=31.547619047619, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI4885649, Length=144, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI23510338, Length=166, Percent_Identity=28.3132530120482, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI23510340, Length=166, Percent_Identity=28.3132530120482, Blast_Score=69, Evalue=9e-12,
Organism=Escherichia coli, GI1787048, Length=247, Percent_Identity=42.914979757085, Blast_Score=201, Evalue=4e-53,
Organism=Escherichia coli, GI87082356, Length=247, Percent_Identity=38.4615384615385, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17540406, Length=241, Percent_Identity=43.5684647302905, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193203301, Length=162, Percent_Identity=32.0987654320988, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71984476, Length=175, Percent_Identity=29.1428571428571, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321903, Length=266, Percent_Identity=42.8571428571429, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6325323, Length=163, Percent_Identity=29.4478527607362, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320598, Length=166, Percent_Identity=27.1084337349398, Blast_Score=73, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582879, Length=277, Percent_Identity=39.7111913357401, Blast_Score=205, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24660640, Length=155, Percent_Identity=32.258064516129, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI20129973, Length=164, Percent_Identity=29.8780487804878, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573937, Length=149, Percent_Identity=29.5302013422819, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007901
- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR001763
- InterPro:   IPR000594 [H]

Pfam domain/function: PF05237 MoeZ_MoeB; PF00581 Rhodanese; PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 37893; Mature: 37893

Theoretical pI: Translated: 7.37; Mature: 7.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVFGLCAVLWGIGSLMGAPRSARAMMIGILYVGVLAMHIALPDRHPLRLATGESPALW
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEE
LLIGGFALVIFSYRQVITRLRTRAKAVEKQSDDALDRPLFNTSELNRYARHMVLREIGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GQKRLKEAKVLVIGAGGLGAPILQYLAAAGVGTIGVIDDDMVENANLQRQVIHRDASIGM
CHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCHHHHHHHHHHCCCH
AKVFSAQAEMTAQNPYVEVRPYNRRLTADIADALFEEYDLVLDGTDNFDTRYLVNETAVK
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEHHHHH
AGIPLISGALSQWEGQLSVFDPAYGAPCYRCVFKSAPAAELASSCAEAGVLGPLPGVIGT
HCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
MMAVEAIKLITDAGTPLRGQMLIYDALYGESRTIAIKPRSDCPSCGPLQAKAS
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLLVFGLCAVLWGIGSLMGAPRSARAMMIGILYVGVLAMHIALPDRHPLRLATGESPALW
CCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEEE
LLIGGFALVIFSYRQVITRLRTRAKAVEKQSDDALDRPLFNTSELNRYARHMVLREIGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCC
GQKRLKEAKVLVIGAGGLGAPILQYLAAAGVGTIGVIDDDMVENANLQRQVIHRDASIGM
CHHHHHHCCEEEEECCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCHHHHHHHHHHCCCH
AKVFSAQAEMTAQNPYVEVRPYNRRLTADIADALFEEYDLVLDGTDNFDTRYLVNETAVK
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHCCEEECCCCCCCCEEEEEHHHHH
AGIPLISGALSQWEGQLSVFDPAYGAPCYRCVFKSAPAAELASSCAEAGVLGPLPGVIGT
HCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHH
MMAVEAIKLITDAGTPLRGQMLIYDALYGESRTIAIKPRSDCPSCGPLQAKAS
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]