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The map label for this gene is siaT [H]

Identifier: 110678391

GI number: 110678391

Start: 1011908

End: 1013185

Strand: Reverse

Name: siaT [H]

Synonym: RD1_1049

Alternate gene names: 110678391

Gene position: 1013185-1011908 (Counterclockwise)

Preceding gene: 110678392

Following gene: 110678390

Centisome position: 24.51

GC content: 58.76

Gene sequence:

>1278_bases
ATGGGCCTCACTGTTCTTATTGCCGTTTTCGTCATCGGTCTTGTCGTGGGCATCCCCGTGGCCATCACTCTCGGCCTGAG
CTCCCTCTGCTATCTGCTGGTCACGGGTATTCCTGTGGTCGTCATGCCACAGAAAATGTATGCGGGCATGGATGTTTTCG
TTTTGCTCAGCATCCCCGGCTTTATTCTCGCAGGCAACCTGATGAACCGGGGCGGTATCACGGAACGGATCATCCGCTTT
GCCAATGCGCTGGTCGGTTGGATCAGGGGGGGCCTTGGCCTCACGAACGTGGGCGCGTCGATGCTGTTCGGGGGCATCAC
CGGCACGGCGGTGGCCGATGCGGCATCCATCGGCGGCGTCATGATACCGGGCATGAAAAAGGCCGGATACCCCGCCGATT
TTTCTGCCGCCATCACCGCCGCCTCCTCCACCGTCGGGCCGATCATTCCGCCAAGCGTGCCGATGATCATCGTCGGGGCC
TTGTCCGGTATCTCTGTCGGAAAGATGTTCCTGGCCGGAGCGATACCGGGCATTCTGCTGGGTATGGCGATGATGATCAC
CACCTATGTGATTGCGCGCCGCCGGAATTTTCCCAAACAGGAATGGCAGGGCGTGGGCGAAATCGGGCGGTCCTTTGCGG
GCGCGTTCTGGGCGCTCGCGATGACCGCTTTGATCCTTTACGGTCTGCTCAGCGGCGTGGCGACACCGACGGAAACGGCA
ATCATCGCAAGTGTCTATGCCATGTTCATCGGGCTTGTCGTCTACCGCGAACTTCCGTTCCGTGAAATACCCAGGATCAT
TGTCGACAGCGCTGTTGCCGCATCGGGGATTCTGGTTCTGGTCGGGTTTGCGAATGTGTTCGGCTGGATCCTCGTCTCCG
AGCGTATTCCACAGGCGATCGCCGCCGCTGTGTTGTCGTTCACGGAAAACAAATTCATCATCATCCTGATCATCAACGTC
CTGCTGCTGATTGTCGGCATGTTCATGGAAACGATTGCGGCTCTGATCATCCTCTTTGTCCCGCTTCTGACGCTTGCGAC
CTCCGTGGGGATTGACCCGCTGCATTTTGCGACCTTCGCGGTGCTGAACCTGATGATCGGCCTGACCACCCCGCCCCTTG
GCGTGTGCCTGTTTGTCTGCGCGGGGATCGCGCGATTGCCCTTGACCCCCGTTATCATCGCGATCCTGCCGTTTATCGCG
ACAAACATCATCGTTCTGTTGATGGTGTCCTACTTCCCCCCGCTGGCGACCTGGTTGCCCTCTGTCCTTATACCGTAA

Upstream 100 bases:

>100_bases
CATTGCTCGCCTGCCTTGCGGTTTTTGCCCTGCTGAGGATCGTTTCGATGCTCTTTTTTGCCGGCACGGGTGAGCCGGTC
AAACGTATGGATAGCTGACC

Downstream 100 bases:

>100_bases
AAGGAGGTTTTCGTGACCACCACAATTTGCAGACTTCACAGCAAAGGTGACTTGCGCGTTGAGGAGATCGCTTCACCGCC
TCTGGAAGCGGGCGACGTCG

Product: TRAP dicarboxylate transporter, DctM subunit

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MGLTVLIAVFVIGLVVGIPVAITLGLSSLCYLLVTGIPVVVMPQKMYAGMDVFVLLSIPGFILAGNLMNRGGITERIIRF
ANALVGWIRGGLGLTNVGASMLFGGITGTAVADAASIGGVMIPGMKKAGYPADFSAAITAASSTVGPIIPPSVPMIIVGA
LSGISVGKMFLAGAIPGILLGMAMMITTYVIARRRNFPKQEWQGVGEIGRSFAGAFWALAMTALILYGLLSGVATPTETA
IIASVYAMFIGLVVYRELPFREIPRIIVDSAVAASGILVLVGFANVFGWILVSERIPQAIAAAVLSFTENKFIIILIINV
LLLIVGMFMETIAALIILFVPLLTLATSVGIDPLHFATFAVLNLMIGLTTPPLGVCLFVCAGIARLPLTPVIIAILPFIA
TNIIVLLMVSYFPPLATWLPSVLIP

Sequences:

>Translated_425_residues
MGLTVLIAVFVIGLVVGIPVAITLGLSSLCYLLVTGIPVVVMPQKMYAGMDVFVLLSIPGFILAGNLMNRGGITERIIRF
ANALVGWIRGGLGLTNVGASMLFGGITGTAVADAASIGGVMIPGMKKAGYPADFSAAITAASSTVGPIIPPSVPMIIVGA
LSGISVGKMFLAGAIPGILLGMAMMITTYVIARRRNFPKQEWQGVGEIGRSFAGAFWALAMTALILYGLLSGVATPTETA
IIASVYAMFIGLVVYRELPFREIPRIIVDSAVAASGILVLVGFANVFGWILVSERIPQAIAAAVLSFTENKFIIILIINV
LLLIVGMFMETIAALIILFVPLLTLATSVGIDPLHFATFAVLNLMIGLTTPPLGVCLFVCAGIARLPLTPVIIAILPFIA
TNIIVLLMVSYFPPLATWLPSVLIP
>Mature_424_residues
GLTVLIAVFVIGLVVGIPVAITLGLSSLCYLLVTGIPVVVMPQKMYAGMDVFVLLSIPGFILAGNLMNRGGITERIIRFA
NALVGWIRGGLGLTNVGASMLFGGITGTAVADAASIGGVMIPGMKKAGYPADFSAAITAASSTVGPIIPPSVPMIIVGAL
SGISVGKMFLAGAIPGILLGMAMMITTYVIARRRNFPKQEWQGVGEIGRSFAGAFWALAMTALILYGLLSGVATPTETAI
IASVYAMFIGLVVYRELPFREIPRIIVDSAVAASGILVLVGFANVFGWILVSERIPQAIAAAVLSFTENKFIIILIINVL
LLIVGMFMETIAALIILFVPLLTLATSVGIDPLHFATFAVLNLMIGLTTPPLGVCLFVCAGIARLPLTPVIIAILPFIAT
NIIVLLMVSYFPPLATWLPSVLIP

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG1593

COG function: function code G; TRAP-type C4-dicarboxylate transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=398, Percent_Identity=35.1758793969849, Blast_Score=216, Evalue=2e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 44438; Mature: 44307

Theoretical pI: Translated: 9.38; Mature: 9.38

Prosite motif: PS00457 NA_SOLUT_SYMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLTVLIAVFVIGLVVGIPVAITLGLSSLCYLLVTGIPVVVMPQKMYAGMDVFVLLSIPG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCCHHHHHHHCCH
FILAGNLMNRGGITERIIRFANALVGWIRGGLGLTNVGASMLFGGITGTAVADAASIGGV
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCE
MIPGMKKAGYPADFSAAITAASSTVGPIIPPSVPMIIVGALSGISVGKMFLAGAIPGILL
ECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
GMAMMITTYVIARRRNFPKQEWQGVGEIGRSFAGAFWALAMTALILYGLLSGVATPTETA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IIASVYAMFIGLVVYRELPFREIPRIIVDSAVAASGILVLVGFANVFGWILVSERIPQAI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAVLSFTENKFIIILIINVLLLIVGMFMETIAALIILFVPLLTLATSVGIDPLHFATFA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VLNLMIGLTTPPLGVCLFVCAGIARLPLTPVIIAILPFIATNIIVLLMVSYFPPLATWLP
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SVLIP
HHCCC
>Mature Secondary Structure 
GLTVLIAVFVIGLVVGIPVAITLGLSSLCYLLVTGIPVVVMPQKMYAGMDVFVLLSIPG
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHCCCHHHHHHHCCH
FILAGNLMNRGGITERIIRFANALVGWIRGGLGLTNVGASMLFGGITGTAVADAASIGGV
HHHCCCHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCE
MIPGMKKAGYPADFSAAITAASSTVGPIIPPSVPMIIVGALSGISVGKMFLAGAIPGILL
ECCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHH
GMAMMITTYVIARRRNFPKQEWQGVGEIGRSFAGAFWALAMTALILYGLLSGVATPTETA
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
IIASVYAMFIGLVVYRELPFREIPRIIVDSAVAASGILVLVGFANVFGWILVSERIPQAI
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAVLSFTENKFIIILIINVLLLIVGMFMETIAALIILFVPLLTLATSVGIDPLHFATFA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
VLNLMIGLTTPPLGVCLFVCAGIARLPLTPVIIAILPFIATNIIVLLMVSYFPPLATWLP
HHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH
SVLIP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]