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The map label for this gene is fadH [H]

Identifier: 110678304

GI number: 110678304

Start: 924183

End: 926210

Strand: Reverse

Name: fadH [H]

Synonym: RD1_0957

Alternate gene names: 110678304

Gene position: 926210-924183 (Counterclockwise)

Preceding gene: 110678306

Following gene: 110678302

Centisome position: 22.41

GC content: 60.06

Gene sequence:

>2028_bases
ATGGCCAACTATCCAAATCTACTGGCGCCGCTGGATCTTGGCTTTACGACGCTGAAAAACCGCGTGTTGATGGGGTCGAT
GCACACTGGCCTTGAAGAAACCAAGGACTGGAACCGGGTCGCTGAGTTTTATGCCGAACGCGCCAGAGGCGAGGTCGCCC
TGATGGTCACAGGCGGGATTGGCCCCAACCTCGAAGGCTCTGTCCTGCCGGGTGCGGCCATGATGGTCAGCGATCAGGAT
GTGGCAAACCACAAGGTCATTACGGATCGGGTGCATGAGGCGGGCGGCAAAATCGCCATGCAAATCCTGCATGCGGGCCG
CTACGCCTATGGGCCCAAATGCGTCGCACCCTCGGCCATCAAATCCCCGATCTCGCCTTTCGCACCGGCCGAGTTGGACG
CCGACGGGATCGAAAAACAGATCAGCGATATCGTTGCCTGCGCCGCCCGCGCGCAGGAGGCCGGATATGACGGCGTCGAG
ATCATGGGATCTGAGGGATATTTCCTGAACCAGTTTCTGGTCACCCATACCAACAAGCGCACGGACGAATGGGGCGGGTC
ATATGAAAACCGCATGCGCCTGCCTGTTGAGGTCGTGCGCCGCGTGCGCGCGGCTGTGGGCACCGATTTCATCATCATCT
ACCGGCTGTCGATGATTGACCTGATTCCGAACGGCTCCACCCATGACGAGGTCGTTCAGCTTGCACAGGCGGTCGAGGCG
GCAGGCGCCACGATCATCAACACCGGCATCGGCTGGCACGAAGCGCGCATTCCGACAATCGCCACATCCGTTCCCCGCGC
GGCCTTTGCATGGGTCACCAAAAAGCTGATGGGCAAGGTCGGGATTCCGGTCATTACCTCCAACCGCATCAACACGCCAG
ACGTTGCCGAGGAGGTACTTGCCACCGGCTGCGCCGATATGGTGTCGATGGCGCGCCCGATGCTGGCAGATGCGGATTTT
GTGCTCAAAGCCATGCGCGGTAAATCGGGCGAAATCGCACCCTGCATCGCCTGTAATCAGGCCTGTCTGGACCATACGTT
CAGCGGGAAAATATCCAGTTGCCTTGTGAACCCGCGCGCCTGTTATGAGACCGAATTGAAAATCGAACCCGTCACACGAC
CAAAGGCAATTGCCATCGTCGGCGCAGGCCCTGCGGGCCTTTCCACCGCAATCACAGCAGCGCAGCGGGGCCATAATGTC
ACCCTGTTCGATCAGGCGGATGAAATCGGCGGCCAGCTCAACATGGCGAAACAAGTGCCGGGGAAGGAAGAGTTCTGGGG
CCTTGTGGATTGGTACCGCATCATGCTGGACACCACCGGCGTCACGGTATCACTGGGGCAGCCCGTAGGTGCGGATGATT
TAAAAACCTTTGATGAGGTAGTTGTTGCGACAGGCGTGGTCCCGCGCGACCCCGGCATCGAGGGGCAGAATGCGCCGAAT
GTTGTCAGCTACATCGAAGTTCTGCGCGGTACGGCTCAGGTCGGAAAACGCGTCGTGATCGTGGGCGCGGGCGGCATCGG
GTTCGATGTGGCTGAATACCTTGTGCACGAAGGTGAAAGCCCCACGGTAAATCTGCCCGAATGGATGCGCGAATGGGGTG
TTTCTGACCCGGGCGAAAACCGGTCGGGCCTTGCACCGGAAGGTCCGCAGCCCGCCCCGCCCGCGCGCGATGTCACCTTG
CTGCAGCGCAAGGCGGAGAAGCCCGGGAAACGGCTGGGCAAGACCACAGGCTGGATTCACCGGGCGGCGCTTGCCATGAA
AAACGTCAAAATGAAGGGCGGCGTCAATTACGAGAGCGTTAAGGACGGCGGGCTTTTGGTGTCCTTCGGTGAGGCCCGCG
AAAATCCCACTCTGATCGAGGCCGACACAATCGTGTTATGCGCGGGGCAACTGCCCGAAAGATCGCTTGCGGATGCACTT
GATGCTGCTGGCACGCCCTATCACATCATCGGCGGTGCAGATGTGGCCGCAGAACTGGATGCCAAACGCGCAATTGATCA
GGGCACGCGTTTGGCGGCAGTACTTTAG

Upstream 100 bases:

>100_bases
ATCCCGGCATGCGCATTTGCGATTGTGACGCGGCGTTGCGCGTGACAGGCTTTGCCGGATAATGCCATGTCACGACAATA
ATGACCGGGGAGGGTTTCGA

Downstream 100 bases:

>100_bases
AAACTCACTCGACGGTAATGGTAATTACCTCGGACACGATGGGCGTTGCATGTGGTACATGCCCCGAGTCTCCCAAAACA
AGCTGGAGCGTGTGCTGACC

Product: 2,4-dienoyl-CoA reductase

Products: NA

Alternate protein names: 2,4-dienoyl coenzyme A reductase [H]

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MANYPNLLAPLDLGFTTLKNRVLMGSMHTGLEETKDWNRVAEFYAERARGEVALMVTGGIGPNLEGSVLPGAAMMVSDQD
VANHKVITDRVHEAGGKIAMQILHAGRYAYGPKCVAPSAIKSPISPFAPAELDADGIEKQISDIVACAARAQEAGYDGVE
IMGSEGYFLNQFLVTHTNKRTDEWGGSYENRMRLPVEVVRRVRAAVGTDFIIIYRLSMIDLIPNGSTHDEVVQLAQAVEA
AGATIINTGIGWHEARIPTIATSVPRAAFAWVTKKLMGKVGIPVITSNRINTPDVAEEVLATGCADMVSMARPMLADADF
VLKAMRGKSGEIAPCIACNQACLDHTFSGKISSCLVNPRACYETELKIEPVTRPKAIAIVGAGPAGLSTAITAAQRGHNV
TLFDQADEIGGQLNMAKQVPGKEEFWGLVDWYRIMLDTTGVTVSLGQPVGADDLKTFDEVVVATGVVPRDPGIEGQNAPN
VVSYIEVLRGTAQVGKRVVIVGAGGIGFDVAEYLVHEGESPTVNLPEWMREWGVSDPGENRSGLAPEGPQPAPPARDVTL
LQRKAEKPGKRLGKTTGWIHRAALAMKNVKMKGGVNYESVKDGGLLVSFGEARENPTLIEADTIVLCAGQLPERSLADAL
DAAGTPYHIIGGADVAAELDAKRAIDQGTRLAAVL

Sequences:

>Translated_675_residues
MANYPNLLAPLDLGFTTLKNRVLMGSMHTGLEETKDWNRVAEFYAERARGEVALMVTGGIGPNLEGSVLPGAAMMVSDQD
VANHKVITDRVHEAGGKIAMQILHAGRYAYGPKCVAPSAIKSPISPFAPAELDADGIEKQISDIVACAARAQEAGYDGVE
IMGSEGYFLNQFLVTHTNKRTDEWGGSYENRMRLPVEVVRRVRAAVGTDFIIIYRLSMIDLIPNGSTHDEVVQLAQAVEA
AGATIINTGIGWHEARIPTIATSVPRAAFAWVTKKLMGKVGIPVITSNRINTPDVAEEVLATGCADMVSMARPMLADADF
VLKAMRGKSGEIAPCIACNQACLDHTFSGKISSCLVNPRACYETELKIEPVTRPKAIAIVGAGPAGLSTAITAAQRGHNV
TLFDQADEIGGQLNMAKQVPGKEEFWGLVDWYRIMLDTTGVTVSLGQPVGADDLKTFDEVVVATGVVPRDPGIEGQNAPN
VVSYIEVLRGTAQVGKRVVIVGAGGIGFDVAEYLVHEGESPTVNLPEWMREWGVSDPGENRSGLAPEGPQPAPPARDVTL
LQRKAEKPGKRLGKTTGWIHRAALAMKNVKMKGGVNYESVKDGGLLVSFGEARENPTLIEADTIVLCAGQLPERSLADAL
DAAGTPYHIIGGADVAAELDAKRAIDQGTRLAAVL
>Mature_674_residues
ANYPNLLAPLDLGFTTLKNRVLMGSMHTGLEETKDWNRVAEFYAERARGEVALMVTGGIGPNLEGSVLPGAAMMVSDQDV
ANHKVITDRVHEAGGKIAMQILHAGRYAYGPKCVAPSAIKSPISPFAPAELDADGIEKQISDIVACAARAQEAGYDGVEI
MGSEGYFLNQFLVTHTNKRTDEWGGSYENRMRLPVEVVRRVRAAVGTDFIIIYRLSMIDLIPNGSTHDEVVQLAQAVEAA
GATIINTGIGWHEARIPTIATSVPRAAFAWVTKKLMGKVGIPVITSNRINTPDVAEEVLATGCADMVSMARPMLADADFV
LKAMRGKSGEIAPCIACNQACLDHTFSGKISSCLVNPRACYETELKIEPVTRPKAIAIVGAGPAGLSTAITAAQRGHNVT
LFDQADEIGGQLNMAKQVPGKEEFWGLVDWYRIMLDTTGVTVSLGQPVGADDLKTFDEVVVATGVVPRDPGIEGQNAPNV
VSYIEVLRGTAQVGKRVVIVGAGGIGFDVAEYLVHEGESPTVNLPEWMREWGVSDPGENRSGLAPEGPQPAPPARDVTLL
QRKAEKPGKRLGKTTGWIHRAALAMKNVKMKGGVNYESVKDGGLLVSFGEARENPTLIEADTIVLCAGQLPERSLADALD
AAGTPYHIIGGADVAAELDAKRAIDQGTRLAAVL

Specific function: Catalyzes the NADP-dependent reduction of 2,4-dienoyl- CoA to yield trans-2- enoyl-CoA [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789463, Length=672, Percent_Identity=58.3333333333333, Blast_Score=802, Evalue=0.0,
Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=29.3948126801153, Blast_Score=105, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=316, Percent_Identity=26.2658227848101, Blast_Score=94, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17559804, Length=318, Percent_Identity=25.4716981132075, Blast_Score=90, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564188, Length=317, Percent_Identity=23.9747634069401, Blast_Score=89, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17565138, Length=312, Percent_Identity=24.0384615384615, Blast_Score=88, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17540738, Length=271, Percent_Identity=26.1992619926199, Blast_Score=83, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI72001454, Length=256, Percent_Identity=25.390625, Blast_Score=80, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17566914, Length=217, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6321973, Length=235, Percent_Identity=30.6382978723404, Blast_Score=95, Evalue=4e-20,
Organism=Saccharomyces cerevisiae, GI6325086, Length=235, Percent_Identity=30.6382978723404, Blast_Score=93, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR013027
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN; PF07992 Pyr_redox_2 [H]

EC number: =1.3.1.34 [H]

Molecular weight: Translated: 71881; Mature: 71750

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANYPNLLAPLDLGFTTLKNRVLMGSMHTGLEETKDWNRVAEFYAERARGEVALMVTGGI
CCCCCCCCCHHHCCHHHHHCEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GPNLEGSVLPGAAMMVSDQDVANHKVITDRVHEAGGKIAMQILHAGRYAYGPKCVAPSAI
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHH
KSPISPFAPAELDADGIEKQISDIVACAARAQEAGYDGVEIMGSEGYFLNQFLVTHTNKR
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHCCCCC
TDEWGGSYENRMRLPVEVVRRVRAAVGTDFIIIYRLSMIDLIPNGSTHDEVVQLAQAVEA
CHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHH
AGATIINTGIGWHEARIPTIATSVPRAAFAWVTKKLMGKVGIPVITSNRINTPDVAEEVL
CCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
ATGCADMVSMARPMLADADFVLKAMRGKSGEIAPCIACNQACLDHTFSGKISSCLVNPRA
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHCHHHHCCCCCCCHHHHCCCCHH
CYETELKIEPVTRPKAIAIVGAGPAGLSTAITAAQRGHNVTLFDQADEIGGQLNMAKQVP
HCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHCCCEEHHHCCC
GKEEFWGLVDWYRIMLDTTGVTVSLGQPVGADDLKTFDEVVVATGVVPRDPGIEGQNAPN
CHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
VVSYIEVLRGTAQVGKRVVIVGAGGIGFDVAEYLVHEGESPTVNLPEWMREWGVSDPGEN
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC
RSGLAPEGPQPAPPARDVTLLQRKAEKPGKRLGKTTGWIHRAALAMKNVKMKGGVNYESV
CCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCC
KDGGLLVSFGEARENPTLIEADTIVLCAGQLPERSLADALDAAGTPYHIIGGADVAAELD
CCCCEEEEECCCCCCCCEEECCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHH
AKRAIDQGTRLAAVL
HHHHHHCCCEEEEEC
>Mature Secondary Structure 
ANYPNLLAPLDLGFTTLKNRVLMGSMHTGLEETKDWNRVAEFYAERARGEVALMVTGGI
CCCCCCCCHHHCCHHHHHCEEEECHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
GPNLEGSVLPGAAMMVSDQDVANHKVITDRVHEAGGKIAMQILHAGRYAYGPKCVAPSAI
CCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCHHH
KSPISPFAPAELDADGIEKQISDIVACAARAQEAGYDGVEIMGSEGYFLNQFLVTHTNKR
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCEEHHHHHHCCCCC
TDEWGGSYENRMRLPVEVVRRVRAAVGTDFIIIYRLSMIDLIPNGSTHDEVVQLAQAVEA
CHHCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHH
AGATIINTGIGWHEARIPTIATSVPRAAFAWVTKKLMGKVGIPVITSNRINTPDVAEEVL
CCCEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHH
ATGCADMVSMARPMLADADFVLKAMRGKSGEIAPCIACNQACLDHTFSGKISSCLVNPRA
HHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHCHHHHCCCCCCCHHHHCCCCHH
CYETELKIEPVTRPKAIAIVGAGPAGLSTAITAAQRGHNVTLFDQADEIGGQLNMAKQVP
HCCCCEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCCCEEEECCHHHHCCCEEHHHCCC
GKEEFWGLVDWYRIMLDTTGVTVSLGQPVGADDLKTFDEVVVATGVVPRDPGIEGQNAPN
CHHHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
VVSYIEVLRGTAQVGKRVVIVGAGGIGFDVAEYLVHEGESPTVNLPEWMREWGVSDPGEN
HHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCCC
RSGLAPEGPQPAPPARDVTLLQRKAEKPGKRLGKTTGWIHRAALAMKNVKMKGGVNYESV
CCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHCCHHHHHHHHHHHHHHEECCCCCCCCCC
KDGGLLVSFGEARENPTLIEADTIVLCAGQLPERSLADALDAAGTPYHIIGGADVAAELD
CCCCEEEEECCCCCCCCEEECCEEEEECCCCCCHHHHHHHHCCCCCEEEECCCCHHHHHH
AKRAIDQGTRLAAVL
HHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9346310; 9278503 [H]