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The map label for this gene is bvgS [H]

Identifier: 110678228

GI number: 110678228

Start: 857107

End: 859299

Strand: Direct

Name: bvgS [H]

Synonym: RD1_0881

Alternate gene names: 110678228

Gene position: 857107-859299 (Clockwise)

Preceding gene: 110678227

Following gene: 110678229

Centisome position: 20.74

GC content: 58.69

Gene sequence:

>2193_bases
ATGCGCCGCGCGGGTCGGCAAAAAGACGTCGGCCCGTCTGCCTACCGTGCCTTTCAGTCTGCCATTGAATTGCAGCAAAA
GATGGCCGCGCAGTCGCTCGAACTTGAAAGTGTCCGCTATGAACGGGAACGCACGCGCAAGACCCTCGCGGAGGCGCTGG
GGTCGATGGAAGGGGGCCTTGCGCTTTTCTCCGACGGGACGCTGAACATCTGCAACGACCTGTTCAAAGGCCTGCTGCCG
GATATTTCGGATCAGATCGTGCCGGGGCTGAGCCTTGCGCGGTACTTTGATCTGATGAGCAGCAGCGAATATCTGATCTC
GACGGATCGCAAGCTGTTCACCATGCGCGGCGCGTTGGAGAGTGATCAGAACGAAGGGTCGGTCGTATCCTTGGTGGCAG
AGGTTGCCAAGGACCGCTGGTATCAGATGAGCACGCAGCAGACATCGCCGGAGAACACGGTTCTGCTGCTGACGGAAATC
ACCGCGCTGGTGCGCCACAACCGGCGCGAAAAAGAGCATTTGATCGACCGTCAGGCGGATTACCTGCAAGCGGTATTCCA
GAACATGAGTTCGGGTGTTTGTACGTTTTCGGCCACCGGCGAGTTGATGATGCAAAACGGCCAGTTCCGCAGTATTCTGG
GTGTGCCACTCAGCGTGTTGCAGCCGGGCACGCCGTTGCAGGAATTGCTGGATTTCATGCGGTCCAAATCGCTGATCACG
GATAACGCCCTGTTGCAGATGGACGCCTGGCGGGACGAACTGAACAGGAAGGGGGCCGTGAGCACGCGGGTGTCGCATGG
TGCCGCGCGGGTGCTTGATGTTCAGGCCAACCTTTTGCCGGATGGCGGTTTTCTGGTGGAGTTGAAAGACGTGACGCTGG
AGGTCCGCTCTACCGAGATGCTGGAAAACCGTGTGATGGAGCGTACCGCAGAGCTGACCCGCGCGAATGCGAATCTGACC
GAACAATATGAGGAAAAAGCCCGCGTTGAAGAAGAACTGCGCGTGGCAAAAGAACGCGCGGAGGCCGCCGTGTCATCAAA
AACACGGTTCCTGGCGGCGGCCAGCCACGATCTTCTGCAGCCGATCAATGCCGCGAAACTGCTGATTTCCTCCTTGCAGG
AAACCACCCGCGAAACGCGCTTTCGCCCGATGGTCGAACGGCTGGAAGGCGCCTTTGCCTCGGCGGAATACCTGCTGCAT
TCGCTGCTGGATATTTCACGACTGGAAAGCGCGGACCTTGACACGGTGACGACGACAAACGTCAGCCTTGAGGGGTTCAT
GCTTGGCATCAAGGCCGATCAGATGATGCTGGCGGCGCAGAAATCGGTTCAGTTTCATGTTGTGCCCTGCAGTCTGGTGG
TGCGCTCTGATCCGGTTTATCTGCTGCGCTCCATTCAGAACCTAGTGGTGAATGCCATTCAATATACCGATCCGGGGGGG
CGGGTGCTGCTGGGGTGCAGGCGCACCGGAGACACGGTCGTGCTGGAGGTCTGGGACACCGGCATCGGGATCAATATCAA
GGACCAGTCGCGTATCTTTGACGCCTTCACACGCGCAGAAAACGTGCCGATAGGTTCCGGGGTTGGTCTGGGTCTGTCGG
TGGTCGACAGAGCGTGCCGTCTGTTGGGTCACAAGCTTTCGGTGCGTTCAAAACCCGGTGTCGGCTCCGTTTTCAGCATT
GAGATGGAGGTGGTCAAGGGCGCGCCCAGCATGCCTATTCTGCAAGGTCCCATTGAGGACACGGCGGATGCGGCCCTAGA
TTACATCGTGATGGTCATCGAAAATGACGCTGATGTGCTTTACGGCGTGACGCAGCGGCTGGAGCTTTGGGGCGCGAGCG
TGCTGGCGGCACGTACCACTGCTGAAGCGCTCGATTTCATTGATGATCTGGGAATGCCACCCGATATCATTCTGGCCGAT
TATCAATTGGACGCCGGTGAAACCGGTGTACAGGCGACCCTTGATCTGCGCGCCAAGACCGGCACTGCGATCCCTGCGAT
CCTGATCACGGCGGACCGTAGCGAAACAGTGCGTCGCCTCGGTGCGCAGCATGATATGTCTGTGATGACCAAACCTGCGG
AGTTGTCGCGCCTGCGACGGCTGGTGGATTGGAAGGTGCGTGGCCGTGCCGCCCGCGCCGATACGTCTCATAAAAGGGTA
CATACAAAAGTCGAAGGTGACAGTCCCGCATGA

Upstream 100 bases:

>100_bases
TTTTTGCACCTGAGCCGAGGGTTTTGTTTTGAGTATGATCAACCCTGATGACCCGCTTGAGGTAAGGGTCGAAAAGCAGG
CCAAGATCATCGAGGCGCTG

Downstream 100 bases:

>100_bases
GGCCCGCACACTCATATTCAGGAGGAAGCCCATATGTTTAGATTCCCAGCCATCCTATTTGCGATGTTTCTGGCCACAGG
AATGGCGGTTGCCGCCCCCG

Product: histidine kinase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 730; Mature: 730

Protein sequence:

>730_residues
MRRAGRQKDVGPSAYRAFQSAIELQQKMAAQSLELESVRYERERTRKTLAEALGSMEGGLALFSDGTLNICNDLFKGLLP
DISDQIVPGLSLARYFDLMSSSEYLISTDRKLFTMRGALESDQNEGSVVSLVAEVAKDRWYQMSTQQTSPENTVLLLTEI
TALVRHNRREKEHLIDRQADYLQAVFQNMSSGVCTFSATGELMMQNGQFRSILGVPLSVLQPGTPLQELLDFMRSKSLIT
DNALLQMDAWRDELNRKGAVSTRVSHGAARVLDVQANLLPDGGFLVELKDVTLEVRSTEMLENRVMERTAELTRANANLT
EQYEEKARVEEELRVAKERAEAAVSSKTRFLAAASHDLLQPINAAKLLISSLQETTRETRFRPMVERLEGAFASAEYLLH
SLLDISRLESADLDTVTTTNVSLEGFMLGIKADQMMLAAQKSVQFHVVPCSLVVRSDPVYLLRSIQNLVVNAIQYTDPGG
RVLLGCRRTGDTVVLEVWDTGIGINIKDQSRIFDAFTRAENVPIGSGVGLGLSVVDRACRLLGHKLSVRSKPGVGSVFSI
EMEVVKGAPSMPILQGPIEDTADAALDYIVMVIENDADVLYGVTQRLELWGASVLAARTTAEALDFIDDLGMPPDIILAD
YQLDAGETGVQATLDLRAKTGTAIPAILITADRSETVRRLGAQHDMSVMTKPAELSRLRRLVDWKVRGRAARADTSHKRV
HTKVEGDSPA

Sequences:

>Translated_730_residues
MRRAGRQKDVGPSAYRAFQSAIELQQKMAAQSLELESVRYERERTRKTLAEALGSMEGGLALFSDGTLNICNDLFKGLLP
DISDQIVPGLSLARYFDLMSSSEYLISTDRKLFTMRGALESDQNEGSVVSLVAEVAKDRWYQMSTQQTSPENTVLLLTEI
TALVRHNRREKEHLIDRQADYLQAVFQNMSSGVCTFSATGELMMQNGQFRSILGVPLSVLQPGTPLQELLDFMRSKSLIT
DNALLQMDAWRDELNRKGAVSTRVSHGAARVLDVQANLLPDGGFLVELKDVTLEVRSTEMLENRVMERTAELTRANANLT
EQYEEKARVEEELRVAKERAEAAVSSKTRFLAAASHDLLQPINAAKLLISSLQETTRETRFRPMVERLEGAFASAEYLLH
SLLDISRLESADLDTVTTTNVSLEGFMLGIKADQMMLAAQKSVQFHVVPCSLVVRSDPVYLLRSIQNLVVNAIQYTDPGG
RVLLGCRRTGDTVVLEVWDTGIGINIKDQSRIFDAFTRAENVPIGSGVGLGLSVVDRACRLLGHKLSVRSKPGVGSVFSI
EMEVVKGAPSMPILQGPIEDTADAALDYIVMVIENDADVLYGVTQRLELWGASVLAARTTAEALDFIDDLGMPPDIILAD
YQLDAGETGVQATLDLRAKTGTAIPAILITADRSETVRRLGAQHDMSVMTKPAELSRLRRLVDWKVRGRAARADTSHKRV
HTKVEGDSPA
>Mature_730_residues
MRRAGRQKDVGPSAYRAFQSAIELQQKMAAQSLELESVRYERERTRKTLAEALGSMEGGLALFSDGTLNICNDLFKGLLP
DISDQIVPGLSLARYFDLMSSSEYLISTDRKLFTMRGALESDQNEGSVVSLVAEVAKDRWYQMSTQQTSPENTVLLLTEI
TALVRHNRREKEHLIDRQADYLQAVFQNMSSGVCTFSATGELMMQNGQFRSILGVPLSVLQPGTPLQELLDFMRSKSLIT
DNALLQMDAWRDELNRKGAVSTRVSHGAARVLDVQANLLPDGGFLVELKDVTLEVRSTEMLENRVMERTAELTRANANLT
EQYEEKARVEEELRVAKERAEAAVSSKTRFLAAASHDLLQPINAAKLLISSLQETTRETRFRPMVERLEGAFASAEYLLH
SLLDISRLESADLDTVTTTNVSLEGFMLGIKADQMMLAAQKSVQFHVVPCSLVVRSDPVYLLRSIQNLVVNAIQYTDPGG
RVLLGCRRTGDTVVLEVWDTGIGINIKDQSRIFDAFTRAENVPIGSGVGLGLSVVDRACRLLGHKLSVRSKPGVGSVFSI
EMEVVKGAPSMPILQGPIEDTADAALDYIVMVIENDADVLYGVTQRLELWGASVLAARTTAEALDFIDDLGMPPDIILAD
YQLDAGETGVQATLDLRAKTGTAIPAILITADRSETVRRLGAQHDMSVMTKPAELSRLRRLVDWKVRGRAARADTSHKRV
HTKVEGDSPA

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=254, Percent_Identity=32.2834645669291, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789149, Length=327, Percent_Identity=27.82874617737, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI87081816, Length=362, Percent_Identity=26.7955801104972, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI48994928, Length=310, Percent_Identity=25.1612903225806, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788713, Length=248, Percent_Identity=26.6129032258064, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=206, Percent_Identity=28.1553398058252, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=238, Percent_Identity=24.3697478991597, Blast_Score=67, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 80454; Mature: 80454

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRAGRQKDVGPSAYRAFQSAIELQQKMAAQSLELESVRYERERTRKTLAEALGSMEGGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ALFSDGTLNICNDLFKGLLPDISDQIVPGLSLARYFDLMSSSEYLISTDRKLFTMRGALE
EEECCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCEEEECCCHHEEECCCCC
SDQNEGSVVSLVAEVAKDRWYQMSTQQTSPENTVLLLTEITALVRHNRREKEHLIDRQAD
CCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHH
YLQAVFQNMSSGVCTFSATGELMMQNGQFRSILGVPLSVLQPGTPLQELLDFMRSKSLIT
HHHHHHHHHCCCEEEEECCCHHEECCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCCCCCC
DNALLQMDAWRDELNRKGAVSTRVSHGAARVLDVQANLLPDGGFLVELKDVTLEVRSTEM
CCHHEEHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEEECCEEEHHHHHH
LENRVMERTAELTRANANLTEQYEEKARVEEELRVAKERAEAAVSSKTRFLAAASHDLLQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PINAAKLLISSLQETTRETRFRPMVERLEGAFASAEYLLHSLLDISRLESADLDTVTTTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
VSLEGFMLGIKADQMMLAAQKSVQFHVVPCSLVVRSDPVYLLRSIQNLVVNAIQYTDPGG
EEEEEEEEEECHHHHHHHHHCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
RVLLGCRRTGDTVVLEVWDTGIGINIKDQSRIFDAFTRAENVPIGSGVGLGLSVVDRACR
CEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LLGHKLSVRSKPGVGSVFSIEMEVVKGAPSMPILQGPIEDTADAALDYIVMVIENDADVL
HHCCCCCCCCCCCCCCEEEEEEHEECCCCCCCEECCCCCHHHHHHHHEEEEEEECCCHHH
YGVTQRLELWGASVLAARTTAEALDFIDDLGMPPDIILADYQLDAGETGVQATLDLRAKT
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCC
GTAIPAILITADRSETVRRLGAQHDMSVMTKPAELSRLRRLVDWKVRGRAARADTSHKRV
CCCCCEEEEECCCHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHE
HTKVEGDSPA
EEECCCCCCC
>Mature Secondary Structure
MRRAGRQKDVGPSAYRAFQSAIELQQKMAAQSLELESVRYERERTRKTLAEALGSMEGGL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCE
ALFSDGTLNICNDLFKGLLPDISDQIVPGLSLARYFDLMSSSEYLISTDRKLFTMRGALE
EEECCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHCCCCEEEECCCHHEEECCCCC
SDQNEGSVVSLVAEVAKDRWYQMSTQQTSPENTVLLLTEITALVRHNRREKEHLIDRQAD
CCCCCCHHHHHHHHHHHHHHEECCCCCCCCCCEEEEHHHHHHHHHCCCHHHHHHHHHHHH
YLQAVFQNMSSGVCTFSATGELMMQNGQFRSILGVPLSVLQPGTPLQELLDFMRSKSLIT
HHHHHHHHHCCCEEEEECCCHHEECCCCCHHHHCCCHHHCCCCCCHHHHHHHHHCCCCCC
DNALLQMDAWRDELNRKGAVSTRVSHGAARVLDVQANLLPDGGFLVELKDVTLEVRSTEM
CCHHEEHHHHHHHHCCCCCCHHHHHCCCEEEEEEECCCCCCCCEEEEEECCEEEHHHHHH
LENRVMERTAELTRANANLTEQYEEKARVEEELRVAKERAEAAVSSKTRFLAAASHDLLQ
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PINAAKLLISSLQETTRETRFRPMVERLEGAFASAEYLLHSLLDISRLESADLDTVTTTN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECC
VSLEGFMLGIKADQMMLAAQKSVQFHVVPCSLVVRSDPVYLLRSIQNLVVNAIQYTDPGG
EEEEEEEEEECHHHHHHHHHCCCEEEEEEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCC
RVLLGCRRTGDTVVLEVWDTGIGINIKDQSRIFDAFTRAENVPIGSGVGLGLSVVDRACR
CEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
LLGHKLSVRSKPGVGSVFSIEMEVVKGAPSMPILQGPIEDTADAALDYIVMVIENDADVL
HHCCCCCCCCCCCCCCEEEEEEHEECCCCCCCEECCCCCHHHHHHHHEEEEEEECCCHHH
YGVTQRLELWGASVLAARTTAEALDFIDDLGMPPDIILADYQLDAGETGVQATLDLRAKT
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCEEEEEEECCC
GTAIPAILITADRSETVRRLGAQHDMSVMTKPAELSRLRRLVDWKVRGRAARADTSHKRV
CCCCCEEEEECCCHHHHHHHCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHE
HTKVEGDSPA
EEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]