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The map label for this gene is clpB [H]

Identifier: 110678091

GI number: 110678091

Start: 696573

End: 699191

Strand: Direct

Name: clpB [H]

Synonym: RD1_0721

Alternate gene names: 110678091

Gene position: 696573-699191 (Clockwise)

Preceding gene: 110678088

Following gene: 110678093

Centisome position: 16.85

GC content: 61.13

Gene sequence:

>2619_bases
ATGGACTTGAGCAAGTTCACGGAACGGTCGCGCGGTTTCATCCAGGCGGCACAGACGATAGCGGCGCGCGAAAGCCATCA
GAGGCTGGCCGCCGAACACTTACTGAAAGCATTGATGGACGATGATCAGGGGCTGGCCAGCAATCTGATCTCGGCCGCGG
GCGGGCAACCGGCGCGGGTTCTGGAGTCTGTTGATCTGGCACTGGGTAAAATGCCCAAGGTGACAGGCGATGCGGCACAG
GTATATGTGGATGGCACCACGACCAAGGTTCTCGCCGAGGCGGAGCAACTGGCCAAGAAGGCCGGTGACAGCTTTGTCCC
CGTCGAACGTATATTGATGGCGCTGTGCATGGTGAAATCGGGGGCCAAAACGGCCTTGGATGCAGGAAATGTAACTGCGC
AGGCGTTGAACGGTGCGATCAATGATGTGCGCAAGGGGCGCACAGCGGACACGGCCACTGCCGAAGAAGGCTATGACGCG
TTGAAGAAATACGCGATGGACCTGACGGAGCGGGCCGAGGCGGGCAAGATCGACCCGATTATCGGGCGGGACGAGGAAAT
CCGCCGCGCCATGCAGGTTCTGAGCCGCCGGACCAAGAACAACCCGGTGCTGATCGGGGAGCCGGGTGTCGGTAAAACCG
CGATTGCCGAAGGATTGGCCCTGCGGATCGTGAACGGCGATGTGCCTGAATCCCTGCGCAACAAGAAACTGTTGGCGCTG
GACATGGGCGCGTTGATCGCCGGTGCCAAATTCCGCGGTGAATTCGAAGAGCGTCTTAAGGCGGTGCTGACCGAAGTCAC
CGAGGCGGCGGGGGAGATCATCCTGTTCATTGACGAGATGCACACGCTTGTCGGCGCGGGCAAGGCGGATGGCGCGATGG
ACGCGGCCAACCTCATCAAACCTGCCCTTGCGCGCGGTGAACTGCATTGTGTCGGCGCAACCACGCTGGATGAATACCGC
AAATACGTCGAGAAAGACGCGGCACTGGCCCGTCGGTTCCAGCCTGTGATGGTTCAGGAGCCAACGGTCGAGGATACCGT
TTCGATCCTGCGCGGCATCAAGGAGAAATACGAACTGCACCACGGTGTGCGGATTTCGGATTCGTCTTTGGTTGCCGCTG
CGACGCTGAGCCATCGGTATATCACGGACCGGTTTTTGCCGGATAAGGCGATTGACCTGATGGATGAGGCGGCGTCGCGG
TTGCGCATGGAAGTGGACAGCAAGCCCGAAGAGCTGGATGCGATCGACCGTCAGATCCTGCAGATGCAGATCGAGGCCGA
AGCGCTTCGGCTTGAGGATGACGCGGCGAGCAAGGACCGTCTTGAAACGCTCGAAAAGGAGTTGGCCGAATTGCAGGAGC
GCAGTGATGCGATGACCGCGAAATGGCAGGCAGAGCGGGACAAGATGGCGGGTGCGCGCGACCTCAAGGAGCAGCTTGAT
CACGCCCGCGCGGAGCTGGAAATCGCCAAGCGCGAGGGGAACCTCGGCCGGGCGGGCGAATTGTCCTATGGTGTGATCCC
ACAACTGGAAAAGCAACTGGAGGCTGCCGAGGGGCGGGACGACGGCGACGTGATGGTCGAAGAGGCCGTGCGCCCTGAGC
AGATCGCCAGCGTGGTGGAGCGTTGGACCGGTATCCCGGCGGGCAAGATGCTGGAAGGCGAACGCGATAAACTGCTGCGC
ATGGAAGATCAGTTGCATGGCCGCGTGATCGGGCAGAATTCCGCGGTGCGGGCGATTTCCAACGCGGTGCGGCGTGCCCG
CGCGGGTCTGAACGATGAGAACCGGCCTTTGGGTTCGTTCCTGTTCCTCGGGCCAACCGGTGTTGGTAAAACCGAATTGA
CCAAGGCGGTCGCGGAATTCCTGTTTGACGATGACAATGCGATGGTGCGCATCGACATGTCGGAGTTCATGGAAAAACAC
GCGGTTGCCCGACTGATCGGGGCGCCTCCCGGATATGTCGGCTATGATGAGGGCGGTGTGCTGACCGAAGCTGTGCGGCG
CAGACCCTATCAGGTGGTTCTGTTCGATGAGGTTGAAAAGGCCCATCCGGATGTCTTCAACGTGCTGTTGCAGGTGCTGG
ACGACGGGGTCTTGACCGACGGTCAGGGTCGCACGGTGGATTTCAAGCAAACCTTGATCGTGCTGACGTCAAACCTTGGG
GCGCAGGCGCTCAGCCAGCTGCCCGACGGGGCGGATGCCTCTGCGGCCAAGCGCGATGTGATGGATGCCGTGCGCGCCCA
TTTCCGGCCTGAGTTCCTGAACCGTCTGGACGAGACGATCATCTTTGATCGCCTTGGTCGGGCCGACATGGACGGAATCG
TGGAAATTCAGATGGCGCGTCTGCTCAAGCGGCTGGCCGGGCGCAAGATCGCGCTGGAACTGGATGACGCGGCGCGCATG
TGGCTTGCGGATGAAGGGTATGACCCCGTGTTCGGCGCAAGGCCGTTGAAACGTGTGATACAGCGCGCCTTGCAGGACCC
GCTTGCCGAGATGATTCTGGCAGGGGACGTCAAGGACGGTGATGTCATTCAGGTCAGTGTCGGCAGCGAAGGGCTGCTGA
TCGGAGACCGCGTCGCGGCCACCAACAGGCCCAAGCCGGATGAAGCGGTCGTACACTGA

Upstream 100 bases:

>100_bases
TCGGGTTCCGCTTCCCAAGTAATTGGAAAGGTCCAGGACGCTGACGTGCCGCCAAGCCGGGCGCAGCGCAAAAGGGACGC
TTAACGAAAAGGAGATAGCC

Downstream 100 bases:

>100_bases
CCCACCTTGAAAATTGAAATGGCCCGGCAAATCAGTTTTGCCGGGCCATTGTTTTGCGCAATTGTGAATTAAAGCGTGTG
ACGAAATGCCTGAAACATCA

Product: ATP-dependent Clp protease, ATP-binding subunit ClpB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 872

Protein sequence:

>872_residues
MDLSKFTERSRGFIQAAQTIAARESHQRLAAEHLLKALMDDDQGLASNLISAAGGQPARVLESVDLALGKMPKVTGDAAQ
VYVDGTTTKVLAEAEQLAKKAGDSFVPVERILMALCMVKSGAKTALDAGNVTAQALNGAINDVRKGRTADTATAEEGYDA
LKKYAMDLTERAEAGKIDPIIGRDEEIRRAMQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLRNKKLLAL
DMGALIAGAKFRGEFEERLKAVLTEVTEAAGEIILFIDEMHTLVGAGKADGAMDAANLIKPALARGELHCVGATTLDEYR
KYVEKDAALARRFQPVMVQEPTVEDTVSILRGIKEKYELHHGVRISDSSLVAAATLSHRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEELDAIDRQILQMQIEAEALRLEDDAASKDRLETLEKELAELQERSDAMTAKWQAERDKMAGARDLKEQLD
HARAELEIAKREGNLGRAGELSYGVIPQLEKQLEAAEGRDDGDVMVEEAVRPEQIASVVERWTGIPAGKMLEGERDKLLR
MEDQLHGRVIGQNSAVRAISNAVRRARAGLNDENRPLGSFLFLGPTGVGKTELTKAVAEFLFDDDNAMVRIDMSEFMEKH
AVARLIGAPPGYVGYDEGGVLTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGVLTDGQGRTVDFKQTLIVLTSNLG
AQALSQLPDGADASAAKRDVMDAVRAHFRPEFLNRLDETIIFDRLGRADMDGIVEIQMARLLKRLAGRKIALELDDAARM
WLADEGYDPVFGARPLKRVIQRALQDPLAEMILAGDVKDGDVIQVSVGSEGLLIGDRVAATNRPKPDEAVVH

Sequences:

>Translated_872_residues
MDLSKFTERSRGFIQAAQTIAARESHQRLAAEHLLKALMDDDQGLASNLISAAGGQPARVLESVDLALGKMPKVTGDAAQ
VYVDGTTTKVLAEAEQLAKKAGDSFVPVERILMALCMVKSGAKTALDAGNVTAQALNGAINDVRKGRTADTATAEEGYDA
LKKYAMDLTERAEAGKIDPIIGRDEEIRRAMQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLRNKKLLAL
DMGALIAGAKFRGEFEERLKAVLTEVTEAAGEIILFIDEMHTLVGAGKADGAMDAANLIKPALARGELHCVGATTLDEYR
KYVEKDAALARRFQPVMVQEPTVEDTVSILRGIKEKYELHHGVRISDSSLVAAATLSHRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEELDAIDRQILQMQIEAEALRLEDDAASKDRLETLEKELAELQERSDAMTAKWQAERDKMAGARDLKEQLD
HARAELEIAKREGNLGRAGELSYGVIPQLEKQLEAAEGRDDGDVMVEEAVRPEQIASVVERWTGIPAGKMLEGERDKLLR
MEDQLHGRVIGQNSAVRAISNAVRRARAGLNDENRPLGSFLFLGPTGVGKTELTKAVAEFLFDDDNAMVRIDMSEFMEKH
AVARLIGAPPGYVGYDEGGVLTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGVLTDGQGRTVDFKQTLIVLTSNLG
AQALSQLPDGADASAAKRDVMDAVRAHFRPEFLNRLDETIIFDRLGRADMDGIVEIQMARLLKRLAGRKIALELDDAARM
WLADEGYDPVFGARPLKRVIQRALQDPLAEMILAGDVKDGDVIQVSVGSEGLLIGDRVAATNRPKPDEAVVH
>Mature_872_residues
MDLSKFTERSRGFIQAAQTIAARESHQRLAAEHLLKALMDDDQGLASNLISAAGGQPARVLESVDLALGKMPKVTGDAAQ
VYVDGTTTKVLAEAEQLAKKAGDSFVPVERILMALCMVKSGAKTALDAGNVTAQALNGAINDVRKGRTADTATAEEGYDA
LKKYAMDLTERAEAGKIDPIIGRDEEIRRAMQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLRNKKLLAL
DMGALIAGAKFRGEFEERLKAVLTEVTEAAGEIILFIDEMHTLVGAGKADGAMDAANLIKPALARGELHCVGATTLDEYR
KYVEKDAALARRFQPVMVQEPTVEDTVSILRGIKEKYELHHGVRISDSSLVAAATLSHRYITDRFLPDKAIDLMDEAASR
LRMEVDSKPEELDAIDRQILQMQIEAEALRLEDDAASKDRLETLEKELAELQERSDAMTAKWQAERDKMAGARDLKEQLD
HARAELEIAKREGNLGRAGELSYGVIPQLEKQLEAAEGRDDGDVMVEEAVRPEQIASVVERWTGIPAGKMLEGERDKLLR
MEDQLHGRVIGQNSAVRAISNAVRRARAGLNDENRPLGSFLFLGPTGVGKTELTKAVAEFLFDDDNAMVRIDMSEFMEKH
AVARLIGAPPGYVGYDEGGVLTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGVLTDGQGRTVDFKQTLIVLTSNLG
AQALSQLPDGADASAAKRDVMDAVRAHFRPEFLNRLDETIIFDRLGRADMDGIVEIQMARLLKRLAGRKIALELDDAARM
WLADEGYDPVFGARPLKRVIQRALQDPLAEMILAGDVKDGDVIQVSVGSEGLLIGDRVAATNRPKPDEAVVH

Specific function: Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the clpA/clpB family [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=317, Percent_Identity=36.5930599369085, Blast_Score=197, Evalue=3e-50,
Organism=Escherichia coli, GI1788943, Length=864, Percent_Identity=55.787037037037, Blast_Score=974, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=316, Percent_Identity=45.8860759493671, Blast_Score=290, Evalue=3e-79,
Organism=Saccharomyces cerevisiae, GI6320464, Length=701, Percent_Identity=54.2082738944365, Blast_Score=782, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=863, Percent_Identity=43.6848203939745, Blast_Score=673, Evalue=0.0,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR017730
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small [H]

EC number: NA

Molecular weight: Translated: 95250; Mature: 95250

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLSKFTERSRGFIQAAQTIAARESHQRLAAEHLLKALMDDDQGLASNLISAAGGQPARV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
LESVDLALGKMPKVTGDAAQVYVDGTTTKVLAEAEQLAKKAGDSFVPVERILMALCMVKS
HHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GAKTALDAGNVTAQALNGAINDVRKGRTADTATAEEGYDALKKYAMDLTERAEAGKIDPI
CCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDEEIRRAMQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLRNKKLLAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCHHHHCCEEEEE
DMGALIAGAKFRGEFEERLKAVLTEVTEAAGEIILFIDEMHTLVGAGKADGAMDAANLIK
EHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHH
PALARGELHCVGATTLDEYRKYVEKDAALARRFQPVMVQEPTVEDTVSILRGIKEKYELH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHH
HGVRISDSSLVAAATLSHRYITDRFLPDKAIDLMDEAASRLRMEVDSKPEELDAIDRQIL
CCCEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QMQIEAEALRLEDDAASKDRLETLEKELAELQERSDAMTAKWQAERDKMAGARDLKEQLD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HARAELEIAKREGNLGRAGELSYGVIPQLEKQLEAAEGRDDGDVMVEEAVRPEQIASVVE
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHH
RWTGIPAGKMLEGERDKLLRMEDQLHGRVIGQNSAVRAISNAVRRARAGLNDENRPLGSF
HHCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
LFLGPTGVGKTELTKAVAEFLFDDDNAMVRIDMSEFMEKHAVARLIGAPPGYVGYDEGGV
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGVLTDGQGRTVDFKQTLIVLTSNLG
HHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCEECCCCCEEHHHHEEEHHCCCCC
AQALSQLPDGADASAAKRDVMDAVRAHFRPEFLNRLDETIIFDRLGRADMDGIVEIQMAR
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLKRLAGRKIALELDDAARMWLADEGYDPVFGARPLKRVIQRALQDPLAEMILAGDVKDG
HHHHHCCCEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DVIQVSVGSEGLLIGDRVAATNRPKPDEAVVH
CEEEEEECCCCEEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDLSKFTERSRGFIQAAQTIAARESHQRLAAEHLLKALMDDDQGLASNLISAAGGQPARV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
LESVDLALGKMPKVTGDAAQVYVDGTTTKVLAEAEQLAKKAGDSFVPVERILMALCMVKS
HHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
GAKTALDAGNVTAQALNGAINDVRKGRTADTATAEEGYDALKKYAMDLTERAEAGKIDPI
CCCHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCC
IGRDEEIRRAMQVLSRRTKNNPVLIGEPGVGKTAIAEGLALRIVNGDVPESLRNKKLLAL
CCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHCCCEEEEECCCCCHHHHCCEEEEE
DMGALIAGAKFRGEFEERLKAVLTEVTEAAGEIILFIDEMHTLVGAGKADGAMDAANLIK
EHHHHHHCHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHHCCCCCCCCHHHHHHHH
PALARGELHCVGATTLDEYRKYVEKDAALARRFQPVMVQEPTVEDTVSILRGIKEKYELH
HHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHH
HGVRISDSSLVAAATLSHRYITDRFLPDKAIDLMDEAASRLRMEVDSKPEELDAIDRQIL
CCCEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
QMQIEAEALRLEDDAASKDRLETLEKELAELQERSDAMTAKWQAERDKMAGARDLKEQLD
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
HARAELEIAKREGNLGRAGELSYGVIPQLEKQLEAAEGRDDGDVMVEEAVRPEQIASVVE
HHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHH
RWTGIPAGKMLEGERDKLLRMEDQLHGRVIGQNSAVRAISNAVRRARAGLNDENRPLGSF
HHCCCCCCCCCCCCHHHHHHHHHHHCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCE
LFLGPTGVGKTELTKAVAEFLFDDDNAMVRIDMSEFMEKHAVARLIGAPPGYVGYDEGGV
EEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCCH
LTEAVRRRPYQVVLFDEVEKAHPDVFNVLLQVLDDGVLTDGQGRTVDFKQTLIVLTSNLG
HHHHHHCCCCEEEEECCHHHHCCHHHHHHHHHHCCCCEECCCCCEEHHHHEEEHHCCCCC
AQALSQLPDGADASAAKRDVMDAVRAHFRPEFLNRLDETIIFDRLGRADMDGIVEIQMAR
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
LLKRLAGRKIALELDDAARMWLADEGYDPVFGARPLKRVIQRALQDPLAEMILAGDVKDG
HHHHHCCCEEEEEECHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DVIQVSVGSEGLLIGDRVAATNRPKPDEAVVH
CEEEEEECCCCEEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]