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The map label for this gene is nudF [H]

Identifier: 110677922

GI number: 110677922

Start: 522162

End: 522704

Strand: Direct

Name: nudF [H]

Synonym: RD1_0538

Alternate gene names: 110677922

Gene position: 522162-522704 (Clockwise)

Preceding gene: 110677921

Following gene: 110677924

Centisome position: 12.63

GC content: 54.88

Gene sequence:

>543_bases
ATGAGCGAAATCAAAAGGCAATTCCGCCGGACCGTTTATGAAAACAGATGGATGAAGGTGCACGAGGATGCGGTGACTTT
TCCCGATGGATCAGACGGGATTTACGGCGTCGTTGACAAAGAAGACTTTGTTCTGATTGTCCCGCAGCATGCAGATGGGC
GGTTTCAACTGGTGCAGCAGTTTCGCTATCCGGTGGGCGGGCGCTATTGGGAATTCCCGCAAGGGTCATGGGAAACGAGG
CCGGGCACGGACCCGGAAAAGGTCGCCCTCGCCGAATTGGAGGAGGAGACCGGCTTTCGCGCGCAATCCCTCATCAGGTT
GGGGCATCTTTTCGAGGCATACGGTTTTTCAAATCAGGGGTTTCACGCGTTTCTGGCAACCGGTCTGCAAGCGGGGCGCG
TAAATCGCGACAAAGAAGAACAGGATATGCAAACCGCGTCGTTCAGTCTTGAGGCGATACATGACATGATCCGCGCTGGG
CAGATCAAGGATGCGCCGAGTATAGCCGCACTTGGGCTATTGGCCATTTCCGAACATGGATAG

Upstream 100 bases:

>100_bases
TGGCCGCCTTCGACCATCGCGCCAGCCTTTGAAGGCCATTCAAGACGTCACGCAGAGCCGGTGCATCGACAGGCGCGTGC
ACCTGAAGGGGAGTGTTGCG

Downstream 100 bases:

>100_bases
AAACCGCGCAACAGGTCAGCGCAAAGAGGGGACCGCGGCGCGCCGTTGCGCCACGGTCCAAACGCATTCTTATGTGGCCG
CGTTATGCAAACGGTGCGTG

Product: hydrolase, putative

Products: NA

Alternate protein names: ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ASPPase; Adenosine diphosphoribose pyrophosphatase; ADPR-PPase [H]

Number of amino acids: Translated: 180; Mature: 179

Protein sequence:

>180_residues
MSEIKRQFRRTVYENRWMKVHEDAVTFPDGSDGIYGVVDKEDFVLIVPQHADGRFQLVQQFRYPVGGRYWEFPQGSWETR
PGTDPEKVALAELEEETGFRAQSLIRLGHLFEAYGFSNQGFHAFLATGLQAGRVNRDKEEQDMQTASFSLEAIHDMIRAG
QIKDAPSIAALGLLAISEHG

Sequences:

>Translated_180_residues
MSEIKRQFRRTVYENRWMKVHEDAVTFPDGSDGIYGVVDKEDFVLIVPQHADGRFQLVQQFRYPVGGRYWEFPQGSWETR
PGTDPEKVALAELEEETGFRAQSLIRLGHLFEAYGFSNQGFHAFLATGLQAGRVNRDKEEQDMQTASFSLEAIHDMIRAG
QIKDAPSIAALGLLAISEHG
>Mature_179_residues
SEIKRQFRRTVYENRWMKVHEDAVTFPDGSDGIYGVVDKEDFVLIVPQHADGRFQLVQQFRYPVGGRYWEFPQGSWETRP
GTDPEKVALAELEEETGFRAQSLIRLGHLFEAYGFSNQGFHAFLATGLQAGRVNRDKEEQDMQTASFSLEAIHDMIRAGQ
IKDAPSIAALGLLAISEHG

Specific function: Acts on ADP-mannose and ADP-glucose as well as ADP- ribose. Prevents glycogen biosynthesis. The reaction catalyzed by this enzyme is a limiting step of the gluconeogenic process [H]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004385
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00293 NUDIX [H]

EC number: =3.6.1.13 [H]

Molecular weight: Translated: 20376; Mature: 20245

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIKRQFRRTVYENRWMKVHEDAVTFPDGSDGIYGVVDKEDFVLIVPQHADGRFQLVQQ
CHHHHHHHHHHHHHCCCEEEECCEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHH
FRYPVGGRYWEFPQGSWETRPGTDPEKVALAELEEETGFRAQSLIRLGHLFEAYGFSNQG
HCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
FHAFLATGLQAGRVNRDKEEQDMQTASFSLEAIHDMIRAGQIKDAPSIAALGLLAISEHG
HHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SEIKRQFRRTVYENRWMKVHEDAVTFPDGSDGIYGVVDKEDFVLIVPQHADGRFQLVQQ
HHHHHHHHHHHHHCCCEEEECCEEECCCCCCCEEEEECCCCEEEEEECCCCCHHHHHHH
FRYPVGGRYWEFPQGSWETRPGTDPEKVALAELEEETGFRAQSLIRLGHLFEAYGFSNQG
HCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC
FHAFLATGLQAGRVNRDKEEQDMQTASFSLEAIHDMIRAGQIKDAPSIAALGLLAISEHG
HHHHHHHCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377; 10542272 [H]