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The map label for this gene is iolE [H]

Identifier: 110677631

GI number: 110677631

Start: 222774

End: 223670

Strand: Direct

Name: iolE [H]

Synonym: RD1_0223

Alternate gene names: 110677631

Gene position: 222774-223670 (Clockwise)

Preceding gene: 110677630

Following gene: 110677632

Centisome position: 5.39

GC content: 59.75

Gene sequence:

>897_bases
ATGACCATCAAAATAGGCAATGCCCCCTGTTCATGGGGTGTGGAGTTTGCGGACGACCCGCGCAACCCCGCGTGGCGCGA
TGTTCTGCGTGAGAACGCCGAAGCCGGATACAAGGGCATCGAACTTGGTCCTGTGGGCTATGTCCCGGAGGACCCGGCGA
TACTGGCAGACGCTTTGGCGGAGTATGATCTGAGCCTGATCGGTGGCGTGGTGTTCCGCCCCTTTCATGACCCGGCGGCC
TGGGATGATGTGCTGGATGCCGCGGTGCGCACCTGCAAAGCGCTCAAGGCGCATGGGGCGGAGCATCTGGTTCTGATCGA
TTCCACCTCGCCGCGACGGGCTGGCACTGCGGGCCGCGCGAATGATGCCGAACAGATGGACAAGGCGGAATGGAGCGCGT
TTCGGGATCGCATCGCCGCCGTCGCGCGCATCGGTGCCGAAGACTACGGGCTGACCGTCGGCATGCATGCGCACGCAGCA
GGCTTTCTCGATTTTGAACCCGAACTTGAGCGGCTCATGAACGAGATCGACGAGAACACGCTCAAGATATGTTTTGATAC
CGGCCACCATTCCTACGCGGGCTTTGACCCCGTCGCCTTTATGGAAAAACACATCGGCCGCATCAGCTACATGCATTTCA
AGGACATCGATCCGGTTGTAAAAGCGGATGTCATCGCCAAGAGCACCGGGTTTTATGACGCCTGCGGGCAGGGTATCTTT
TGCAACCTTGGGGACGGGGATGTGGATTTCCCAAGGGTGCGCGAAATCCTGCTGGAGAGCGGGTTTGACGGCTGGTGCAC
CGTCGAACAGGATTGCGACCCGACCTTGCCCGATACGGATTCGCTGCGGGATGCCAAGCTGAACCGGGCCTATCTCGAAA
CCATCGGTTTTAGCTGA

Upstream 100 bases:

>100_bases
CGGGCTTGAGGTTTCCAATATCGTAGAGGCGGCGCGCCGATCTCATGCGGCGCGCGCATGGCAAGATGTCAACCACGGCT
AACCCGAAGGGAGCAGACAA

Downstream 100 bases:

>100_bases
GAAAGAAGCGGATATGACACGATTGAACTGGGGTATGATCGGCGGCGGCGAAGGCAGCCAGATTGGCCCCGCGCACCGTC
TCGGCGCGCAGGCTGATGGC

Product: hypothetical protein

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTIKIGNAPCSWGVEFADDPRNPAWRDVLRENAEAGYKGIELGPVGYVPEDPAILADALAEYDLSLIGGVVFRPFHDPAA
WDDVLDAAVRTCKALKAHGAEHLVLIDSTSPRRAGTAGRANDAEQMDKAEWSAFRDRIAAVARIGAEDYGLTVGMHAHAA
GFLDFEPELERLMNEIDENTLKICFDTGHHSYAGFDPVAFMEKHIGRISYMHFKDIDPVVKADVIAKSTGFYDACGQGIF
CNLGDGDVDFPRVREILLESGFDGWCTVEQDCDPTLPDTDSLRDAKLNRAYLETIGFS

Sequences:

>Translated_298_residues
MTIKIGNAPCSWGVEFADDPRNPAWRDVLRENAEAGYKGIELGPVGYVPEDPAILADALAEYDLSLIGGVVFRPFHDPAA
WDDVLDAAVRTCKALKAHGAEHLVLIDSTSPRRAGTAGRANDAEQMDKAEWSAFRDRIAAVARIGAEDYGLTVGMHAHAA
GFLDFEPELERLMNEIDENTLKICFDTGHHSYAGFDPVAFMEKHIGRISYMHFKDIDPVVKADVIAKSTGFYDACGQGIF
CNLGDGDVDFPRVREILLESGFDGWCTVEQDCDPTLPDTDSLRDAKLNRAYLETIGFS
>Mature_297_residues
TIKIGNAPCSWGVEFADDPRNPAWRDVLRENAEAGYKGIELGPVGYVPEDPAILADALAEYDLSLIGGVVFRPFHDPAAW
DDVLDAAVRTCKALKAHGAEHLVLIDSTSPRRAGTAGRANDAEQMDKAEWSAFRDRIAAVARIGAEDYGLTVGMHAHAAG
FLDFEPELERLMNEIDENTLKICFDTGHHSYAGFDPVAFMEKHIGRISYMHFKDIDPVVKADVIAKSTGFYDACGQGIFC
NLGDGDVDFPRVREILLESGFDGWCTVEQDCDPTLPDTDSLRDAKLNRAYLETIGFS

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 32701; Mature: 32570

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIGNAPCSWGVEFADDPRNPAWRDVLRENAEAGYKGIELGPVGYVPEDPAILADALA
CEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHH
EYDLSLIGGVVFRPFHDPAAWDDVLDAAVRTCKALKAHGAEHLVLIDSTSPRRAGTAGRA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
NDAEQMDKAEWSAFRDRIAAVARIGAEDYGLTVGMHAHAAGFLDFEPELERLMNEIDENT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHCCCE
LKICFDTGHHSYAGFDPVAFMEKHIGRISYMHFKDIDPVVKADVIAKSTGFYDACGQGIF
EEEEEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCEE
CNLGDGDVDFPRVREILLESGFDGWCTVEQDCDPTLPDTDSLRDAKLNRAYLETIGFS
EECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TIKIGNAPCSWGVEFADDPRNPAWRDVLRENAEAGYKGIELGPVGYVPEDPAILADALA
EEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHHHHHH
EYDLSLIGGVVFRPFHDPAAWDDVLDAAVRTCKALKAHGAEHLVLIDSTSPRRAGTAGRA
HHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCC
NDAEQMDKAEWSAFRDRIAAVARIGAEDYGLTVGMHAHAAGFLDFEPELERLMNEIDENT
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCHHHHHHHHHHCCCE
LKICFDTGHHSYAGFDPVAFMEKHIGRISYMHFKDIDPVVKADVIAKSTGFYDACGQGIF
EEEEEECCCCCCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHCCCCHHHCCCCEE
CNLGDGDVDFPRVREILLESGFDGWCTVEQDCDPTLPDTDSLRDAKLNRAYLETIGFS
EECCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA