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The map label for this gene is ygjG [C]

Identifier: 110677583

GI number: 110677583

Start: 170510

End: 171907

Strand: Direct

Name: ygjG [C]

Synonym: RD1_0172

Alternate gene names: 110677583

Gene position: 170510-171907 (Clockwise)

Preceding gene: 110677582

Following gene: 110677584

Centisome position: 4.13

GC content: 58.58

Gene sequence:

>1398_bases
ATGTCCGCTATCTCGAATCATATGCCAACTGCCGAGTTGCAGGCGTTGGATGCAGCACATCACATGCACCCTTTCACATC
CAACGAGGTGTTGGCCACAAAGGGCGCGCGGGTCATAACGCGCGCTGACGGTGTGTATCTGACGGACAGCGACGGCAACC
GCATTCTGGATGGCATGGCGGGTCTGTGGTGTGTCAACATCGGCTATGGCCGCCCGGAACTCGCAGAGGTAGCCGCGCGG
CAGATGAAAGAGCTGCCTTATTACAACACGTTCTTCATGACGACGCATGTCCCCGCAATTGCCCTTGCGCAAGAGGTCAC
CAAGCTTGCGCCGGCGGGGATGAACAACATCTTCTTTGCCAGCTCCGGGTCGGAGGCAAACGACACGAACATCCGTCTCG
TGCGCACGTACTGGGCGCAAAAGGGCAAGCCGCAGAAATCCCACATCATCAGCCGCAAAAACGCCTACCACGGATCGTCC
GTCGGATCGGGCAGCCTCGGTGGTATGACCTACATGCACGAGCAGGGCGGCATGCCCATTGCCGGCATTCATCACATCAA
CCAGCCCGACTGGTGGTCCGAGGGGGGCGATATGACGCCCGAGGAATTCGGCGTCGCGCGGGCCAAAGAGCTTGAAGCCA
AGATTAACGAGTTGGGCGAAGATAACGTCGCCGCCTTTATCGCAGAGCCTGTGCAGGGCGCGGGCGGCGTGATCGTGCCA
CCTGAGACTTATTGGCCTGAAATCCAGCGCATCTGCGATGAATATGAAATCCTGCTGATCGCCGACGAAGTCATCTGTGG
ATTTGGGCGCCTAGGTGCGTGGTTCGGCTCTGAGGTGATGGGCATTAAACCGCACATCATGACCGTCGCGAAGGGTCTGT
CGTCAGGCTATCAACCCATCGGCGGGTCGATCGTCTGTGACGAGGTGGCCGAAGTGATCGGGCAAACCGAATTCAATCAT
GGCTATACATATTCCGGGCACCCTGTCGCCGCAGCCGTTGCGTTGGAAAACCTGCGCATCCTGCAGGAAGAAAACATCGT
CGAACATGTACGCACCGTGGCGGCCCCTGCGCTGAAGGCGGGGCTTGAAACGCTTGCCGATCATCCGCTGGTCGGTGACG
TGAGTTGCAAGGGCCTGATGGCCTCCCTGGCGCTGACCCCTCATAAGGAGAGTCGGGCAAAGTTCGCATCAGAGCGCGGC
ACGATTGGCACGATCTGCCGCGAGAGAGCTTTCGCGAATAACCTCGTCATGCGCCATGTTGGCGACCGAATGGTGGTATC
TCCCCCGCTGATCATCCAGCAGAACGATATCGACACGCTGGTTGAGCGCGCAGGCAAAGCGCTTGATGAAGCCTATTCCG
AAATCAAATCCGAAGGGCTTCTGAAAGCCGCTTCCTGA

Upstream 100 bases:

>100_bases
ATGCGACAATGAAACCGGATTGATTCGATTGACTCCTCGTAATTTGATCATATTCTGAAATCGAAACCCTATTGTACATT
TCAACAAAGGCAGGTGCCCT

Downstream 100 bases:

>100_bases
CATCAGCAACTTGATATTACATAGAAATAGCAAGCCGCCTAATATGTATCCCGTGCGGATAATCCGACAGCCTGCATGAT
CCACGTCATGCGGGCCGTTT

Product: putative aminotransferase

Products: L-Glutamate; L-Glutamate 5-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 464

Protein sequence:

>465_residues
MSAISNHMPTAELQALDAAHHMHPFTSNEVLATKGARVITRADGVYLTDSDGNRILDGMAGLWCVNIGYGRPELAEVAAR
QMKELPYYNTFFMTTHVPAIALAQEVTKLAPAGMNNIFFASSGSEANDTNIRLVRTYWAQKGKPQKSHIISRKNAYHGSS
VGSGSLGGMTYMHEQGGMPIAGIHHINQPDWWSEGGDMTPEEFGVARAKELEAKINELGEDNVAAFIAEPVQGAGGVIVP
PETYWPEIQRICDEYEILLIADEVICGFGRLGAWFGSEVMGIKPHIMTVAKGLSSGYQPIGGSIVCDEVAEVIGQTEFNH
GYTYSGHPVAAAVALENLRILQEENIVEHVRTVAAPALKAGLETLADHPLVGDVSCKGLMASLALTPHKESRAKFASERG
TIGTICRERAFANNLVMRHVGDRMVVSPPLIIQQNDIDTLVERAGKALDEAYSEIKSEGLLKAAS

Sequences:

>Translated_465_residues
MSAISNHMPTAELQALDAAHHMHPFTSNEVLATKGARVITRADGVYLTDSDGNRILDGMAGLWCVNIGYGRPELAEVAAR
QMKELPYYNTFFMTTHVPAIALAQEVTKLAPAGMNNIFFASSGSEANDTNIRLVRTYWAQKGKPQKSHIISRKNAYHGSS
VGSGSLGGMTYMHEQGGMPIAGIHHINQPDWWSEGGDMTPEEFGVARAKELEAKINELGEDNVAAFIAEPVQGAGGVIVP
PETYWPEIQRICDEYEILLIADEVICGFGRLGAWFGSEVMGIKPHIMTVAKGLSSGYQPIGGSIVCDEVAEVIGQTEFNH
GYTYSGHPVAAAVALENLRILQEENIVEHVRTVAAPALKAGLETLADHPLVGDVSCKGLMASLALTPHKESRAKFASERG
TIGTICRERAFANNLVMRHVGDRMVVSPPLIIQQNDIDTLVERAGKALDEAYSEIKSEGLLKAAS
>Mature_464_residues
SAISNHMPTAELQALDAAHHMHPFTSNEVLATKGARVITRADGVYLTDSDGNRILDGMAGLWCVNIGYGRPELAEVAARQ
MKELPYYNTFFMTTHVPAIALAQEVTKLAPAGMNNIFFASSGSEANDTNIRLVRTYWAQKGKPQKSHIISRKNAYHGSSV
GSGSLGGMTYMHEQGGMPIAGIHHINQPDWWSEGGDMTPEEFGVARAKELEAKINELGEDNVAAFIAEPVQGAGGVIVPP
ETYWPEIQRICDEYEILLIADEVICGFGRLGAWFGSEVMGIKPHIMTVAKGLSSGYQPIGGSIVCDEVAEVIGQTEFNHG
YTYSGHPVAAAVALENLRILQEENIVEHVRTVAAPALKAGLETLADHPLVGDVSCKGLMASLALTPHKESRAKFASERGT
IGTICRERAFANNLVMRHVGDRMVVSPPLIIQQNDIDTLVERAGKALDEAYSEIKSEGLLKAAS

Specific function: Unknown

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=427, Percent_Identity=28.8056206088993, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI4557809, Length=433, Percent_Identity=25.4041570438799, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI37574042, Length=423, Percent_Identity=27.1867612293144, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=27.1428571428571, Blast_Score=129, Evalue=7e-30,
Organism=Homo sapiens, GI226442709, Length=391, Percent_Identity=26.8542199488491, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI24119277, Length=432, Percent_Identity=24.3055555555556, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI284507298, Length=331, Percent_Identity=27.4924471299094, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI188536080, Length=420, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38679950, Length=420, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38679946, Length=420, Percent_Identity=23.3333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI145693181, Length=406, Percent_Identity=28.0788177339901, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1786991, Length=456, Percent_Identity=30.4824561403509, Blast_Score=158, Evalue=7e-40,
Organism=Escherichia coli, GI1789759, Length=409, Percent_Identity=26.8948655256724, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1788044, Length=418, Percent_Identity=27.0334928229665, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1789016, Length=421, Percent_Identity=27.3159144893112, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=26.1658031088083, Blast_Score=121, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI32564660, Length=443, Percent_Identity=27.5395033860045, Blast_Score=141, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI71992977, Length=435, Percent_Identity=24.8275862068966, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=404, Percent_Identity=27.4752475247525, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=31.1787072243346, Blast_Score=119, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323470, Length=452, Percent_Identity=25.6637168141593, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6324386, Length=375, Percent_Identity=28.8, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6324432, Length=354, Percent_Identity=26.5536723163842, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6321456, Length=310, Percent_Identity=26.1290322580645, Blast_Score=70, Evalue=8e-13,
Organism=Drosophila melanogaster, GI161085790, Length=454, Percent_Identity=28.4140969162996, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI28574759, Length=455, Percent_Identity=27.9120879120879, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21356575, Length=366, Percent_Identity=28.9617486338798, Blast_Score=142, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21357415, Length=422, Percent_Identity=25.8293838862559, Blast_Score=137, Evalue=2e-32,
Organism=Drosophila melanogaster, GI281366494, Length=357, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667139, Length=357, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667143, Length=357, Percent_Identity=25.4901960784314, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.13 [C]

Molecular weight: Translated: 50216; Mature: 50084

Theoretical pI: Translated: 5.54; Mature: 5.54

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAISNHMPTAELQALDAAHHMHPFTSNEVLATKGARVITRADGVYLTDSDGNRILDGMA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCEEEECCCCCHHHHCCC
GLWCVNIGYGRPELAEVAARQMKELPYYNTFFMTTHVPAIALAQEVTKLAPAGMNNIFFA
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEE
SSGSEANDTNIRLVRTYWAQKGKPQKSHIISRKNAYHGSSVGSGSLGGMTYMHEQGGMPI
CCCCCCCCCCEEEEEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCE
AGIHHINQPDWWSEGGDMTPEEFGVARAKELEAKINELGEDNVAAFIAEPVQGAGGVIVP
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCCCCCCEEEC
PETYWPEIQRICDEYEILLIADEVICGFGRLGAWFGSEVMGIKPHIMTVAKGLSSGYQPI
CCCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
GGSIVCDEVAEVIGQTEFNHGYTYSGHPVAAAVALENLRILQEENIVEHVRTVAAPALKA
CCCEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLETLADHPLVGDVSCKGLMASLALTPHKESRAKFASERGTIGTICRERAFANNLVMRHV
HHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GDRMVVSPPLIIQQNDIDTLVERAGKALDEAYSEIKSEGLLKAAS
CCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEECCC
>Mature Secondary Structure 
SAISNHMPTAELQALDAAHHMHPFTSNEVLATKGARVITRADGVYLTDSDGNRILDGMA
CCCCCCCCCHHHHHHHHHHHCCCCCCCCEEECCCCEEEEECCCEEEECCCCCHHHHCCC
GLWCVNIGYGRPELAEVAARQMKELPYYNTFFMTTHVPAIALAQEVTKLAPAGMNNIFFA
CEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHCCCCCCCEEEE
SSGSEANDTNIRLVRTYWAQKGKPQKSHIISRKNAYHGSSVGSGSLGGMTYMHEQGGMPI
CCCCCCCCCCEEEEEEEHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCE
AGIHHINQPDWWSEGGDMTPEEFGVARAKELEAKINELGEDNVAAFIAEPVQGAGGVIVP
EEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEHEECCCCCCCCEEEC
PETYWPEIQRICDEYEILLIADEVICGFGRLGAWFGSEVMGIKPHIMTVAKGLSSGYQPI
CCCCCHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCC
GGSIVCDEVAEVIGQTEFNHGYTYSGHPVAAAVALENLRILQEENIVEHVRTVAAPALKA
CCCEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLETLADHPLVGDVSCKGLMASLALTPHKESRAKFASERGTIGTICRERAFANNLVMRHV
HHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHC
GDRMVVSPPLIIQQNDIDTLVERAGKALDEAYSEIKSEGLLKAAS
CCCEEECCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2-Oxoglutarate; Ornithine [C]

Specific reaction: 2-Oxoglutarate + Ornithine --> L-Glutamate + L-Glutamate 5-semialdehyde [C]

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]