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The map label for this gene is crt [H]

Identifier: 110635966

GI number: 110635966

Start: 3932359

End: 3933129

Strand: Reverse

Name: crt [H]

Synonym: Meso_3640

Alternate gene names: 110635966

Gene position: 3933129-3932359 (Counterclockwise)

Preceding gene: 110635967

Following gene: 110635965

Centisome position: 89.14

GC content: 63.94

Gene sequence:

>771_bases
ATGGATGATTTCGTCCTTCTCGAGCGCCGTGGAACCATCGCGGTCCTGACTCTTAACCGTCCGCAAATCCTCAACGCGTG
GCATAGACCGATGCGGGAGCAGCTTCATGCCCATCTTGACGCGCTTGACGGGGAGGAAAGCTGCCGCGCGATCGTGCTGA
CGGGAGCCGGCGACCGGGCGTTCGGCGCCGGCCAAGACCTCAACGAAACGAAGACCTTCGACGAGGACCGTGCCGAAGAG
TGGATCGAGGAGTGGCGGCGCCTCTACCTGCGCATCCGCACCTTGACCAAGCCGCTGGTCTGCGCGCTCAACGGGCTGGC
CGCCGGCTCGGCATTCCAGGTTGCGCTTCTGTGCGACATCCGCGTCGGGCACGAGGGTTCGAAGATGGGCCAGCCGGAAA
TCAACTCCGGCATCGCCAGTTCGCTCGGGCCGTGGATCATGCGCGAAATGCTCGGCCTTTCGCGCACGACGGAACTGGTC
CTGACCGGCCGCATGATGTCCGGCGCGGAGGCGCATCAGATCGGCCTCATCCATCATCTCGTGCCCGCTAGTGAGGTTCT
GCCCAAGGCTCTTGAGATCGCTGCGGAATTGGCGCTGAAGGCGCCGCTGGCGATGCGGCTGAACAAAGCGCGGCTGCACG
AGATGACTGTCGACGGCCTGCTCGACGGGCTCAACGCCGGCATTGCCATGCAGCGCCAGAGCTACGGCAGCGGCGAGCCT
GCCGTGATGATGGAGAACTTTCTCAAGCGAAACAACAAGGCATCGGCGTGA

Upstream 100 bases:

>100_bases
ACAGCGAATCTTACGAAGGAGGCCACCTTGGCGGTTGACAGCGGCGCACAAACATAGCGTAATGTGATATGTAAAATTGC
AATGCAATACGGAATGCAAA

Downstream 100 bases:

>100_bases
GCGCGGAGCAGCCCTGCATGACCTCTCCGTTTCTCCGAATCTTCGACCTTGCGCAGATGGACCCAGAGCGCCTCTATGCA
CGCTTCGGAGAACGCGACAT

Product: enoyl-CoA hydratase/isomerase

Products: NA

Alternate protein names: Crotonase [H]

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MDDFVLLERRGTIAVLTLNRPQILNAWHRPMREQLHAHLDALDGEESCRAIVLTGAGDRAFGAGQDLNETKTFDEDRAEE
WIEEWRRLYLRIRTLTKPLVCALNGLAAGSAFQVALLCDIRVGHEGSKMGQPEINSGIASSLGPWIMREMLGLSRTTELV
LTGRMMSGAEAHQIGLIHHLVPASEVLPKALEIAAELALKAPLAMRLNKARLHEMTVDGLLDGLNAGIAMQRQSYGSGEP
AVMMENFLKRNNKASA

Sequences:

>Translated_256_residues
MDDFVLLERRGTIAVLTLNRPQILNAWHRPMREQLHAHLDALDGEESCRAIVLTGAGDRAFGAGQDLNETKTFDEDRAEE
WIEEWRRLYLRIRTLTKPLVCALNGLAAGSAFQVALLCDIRVGHEGSKMGQPEINSGIASSLGPWIMREMLGLSRTTELV
LTGRMMSGAEAHQIGLIHHLVPASEVLPKALEIAAELALKAPLAMRLNKARLHEMTVDGLLDGLNAGIAMQRQSYGSGEP
AVMMENFLKRNNKASA
>Mature_256_residues
MDDFVLLERRGTIAVLTLNRPQILNAWHRPMREQLHAHLDALDGEESCRAIVLTGAGDRAFGAGQDLNETKTFDEDRAEE
WIEEWRRLYLRIRTLTKPLVCALNGLAAGSAFQVALLCDIRVGHEGSKMGQPEINSGIASSLGPWIMREMLGLSRTTELV
LTGRMMSGAEAHQIGLIHHLVPASEVLPKALEIAAELALKAPLAMRLNKARLHEMTVDGLLDGLNAGIAMQRQSYGSGEP
AVMMENFLKRNNKASA

Specific function: Could Possibly Oxidizes Fatty Acids Using Specific Components (By Similarity). [C]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI194097323, Length=224, Percent_Identity=30.8035714285714, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI4502327, Length=239, Percent_Identity=30.5439330543933, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI37594469, Length=201, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI37594471, Length=201, Percent_Identity=28.3582089552239, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI20127408, Length=182, Percent_Identity=28.021978021978, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI70995211, Length=211, Percent_Identity=27.9620853080569, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI31542718, Length=201, Percent_Identity=25.3731343283582, Blast_Score=68, Evalue=8e-12,
Organism=Escherichia coli, GI1787659, Length=233, Percent_Identity=33.4763948497854, Blast_Score=117, Evalue=5e-28,
Organism=Escherichia coli, GI1788597, Length=207, Percent_Identity=28.0193236714976, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI221142681, Length=206, Percent_Identity=30.5825242718447, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787660, Length=230, Percent_Identity=31.7391304347826, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788682, Length=211, Percent_Identity=29.8578199052133, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082183, Length=248, Percent_Identity=25.4032258064516, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI1790281, Length=179, Percent_Identity=24.5810055865922, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17540714, Length=225, Percent_Identity=28.8888888888889, Blast_Score=119, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17554946, Length=229, Percent_Identity=30.5676855895196, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI25145438, Length=241, Percent_Identity=31.1203319502075, Blast_Score=109, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17534483, Length=221, Percent_Identity=26.2443438914027, Blast_Score=85, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI25144160, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI25144157, Length=190, Percent_Identity=29.4736842105263, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17536985, Length=235, Percent_Identity=26.8085106382979, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17560910, Length=206, Percent_Identity=24.2718446601942, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17558304, Length=183, Percent_Identity=24.5901639344262, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17508951, Length=230, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25144276, Length=230, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17508953, Length=230, Percent_Identity=26.0869565217391, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320241, Length=188, Percent_Identity=26.063829787234, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129971, Length=215, Percent_Identity=32.093023255814, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24653477, Length=215, Percent_Identity=32.093023255814, Blast_Score=114, Evalue=9e-26,
Organism=Drosophila melanogaster, GI24653139, Length=228, Percent_Identity=33.3333333333333, Blast_Score=112, Evalue=2e-25,
Organism=Drosophila melanogaster, GI21357171, Length=199, Percent_Identity=32.1608040201005, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI19920382, Length=210, Percent_Identity=29.5238095238095, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24650670, Length=208, Percent_Identity=30.2884615384615, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24654903, Length=261, Percent_Identity=26.0536398467433, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24583165, Length=215, Percent_Identity=27.4418604651163, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921018, Length=205, Percent_Identity=28.780487804878, Blast_Score=71, Evalue=7e-13,
Organism=Drosophila melanogaster, GI19922422, Length=245, Percent_Identity=24.4897959183673, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.55 [H]

Molecular weight: Translated: 28153; Mature: 28153

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDFVLLERRGTIAVLTLNRPQILNAWHRPMREQLHAHLDALDGEESCRAIVLTGAGDRA
CCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
FGAGQDLNETKTFDEDRAEEWIEEWRRLYLRIRTLTKPLVCALNGLAAGSAFQVALLCDI
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
RVGHEGSKMGQPEINSGIASSLGPWIMREMLGLSRTTELVLTGRMMSGAEAHQIGLIHHL
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHEEECCHHCCCCHHHHHHHHHH
VPASEVLPKALEIAAELALKAPLAMRLNKARLHEMTVDGLLDGLNAGIAMQRQSYGSGEP
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCCC
AVMMENFLKRNNKASA
HHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDDFVLLERRGTIAVLTLNRPQILNAWHRPMREQLHAHLDALDGEESCRAIVLTGAGDRA
CCCEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
FGAGQDLNETKTFDEDRAEEWIEEWRRLYLRIRTLTKPLVCALNGLAAGSAFQVALLCDI
CCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEE
RVGHEGSKMGQPEINSGIASSLGPWIMREMLGLSRTTELVLTGRMMSGAEAHQIGLIHHL
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHEEECCHHCCCCHHHHHHHHHH
VPASEVLPKALEIAAELALKAPLAMRLNKARLHEMTVDGLLDGLNAGIAMQRQSYGSGEP
CCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEHHCCCCCCC
AVMMENFLKRNNKASA
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]