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The map label for this gene is sseA [H]

Identifier: 110635956

GI number: 110635956

Start: 3919495

End: 3920343

Strand: Reverse

Name: sseA [H]

Synonym: Meso_3630

Alternate gene names: 110635956

Gene position: 3920343-3919495 (Counterclockwise)

Preceding gene: 110635957

Following gene: 110635955

Centisome position: 88.85

GC content: 65.72

Gene sequence:

>849_bases
ATGACTGATCCGCTTGTCGACCCCGCCTGGCTCACCGCACGGCTGGACGATCCGCTGGTCGTGCCGCTCGACTGCACCTG
GTACGTGCCGGAGGTGGGAATTTCGGGCCGTGCTCGCTTCGAAGAAGGCCATGTCCCCGGCGCGGTCTATGTCGATCTCG
ACGAAATCTCCGACTCCGCCTCGCCCTATGTCAACATGATGTGCACGTCCGAGACCTTCGAACGCGTCATGAGCGCGCTC
GGCATCGGCAGCGACACCCATGTCGTGGTCTACAACGCCAACTACGTCTCCGCGCGCCTGTGGTGGATGTTCAGGCATTT
CGGCCACGAGGAGGTGTCGATCCTCGACGGCGGCTGGGCGCGCTGGCTGGCGGAGAGACGCCCCGTCGAGACCGGCCCTG
CACGGCCACGGCCGCTCCGCCGGTTCGTCGCCGGAAAGCCCAAGAATGACATTGTAACAGCAGAGATCGTCCTCAACGCT
CTCCGGTCAGGCGATGCGCAGGTGGTCGACGTTCGCCCCAGGGGCAAGTTCGACGGCACCGAACCGACCGGCTATCCCGG
CGTTTTGCCTGGCCACATGCCCGGCGCGGTGAATATCCCCTGGGCCGAGCTCTTCACCGCCGATGCCGAGCGGCGCTTCA
TTGCGCCCGACCGGTTCGAGGCGCTTCTGGCCGAAAGAGGCGTTGACGCGGACAGGCCGATCATCGCCACCTGCGGCTCC
GGCGTCACGGCCGCTATCCTGGCGTTCCACCTCGAACGCATCGGCAGGCATGGCTGGCACATCTATGACGGCTCCTGGCA
CGAGTGGGGCCAGCGGGACGATCTACCCAAGGAGACGTCGAATGGCTGA

Upstream 100 bases:

>100_bases
CGCCGCGGCAGCTGGAACAAGCCGTCTACGAAGGAGCGAAAGTTGCCCGCCAGATATAGACCGGGGGCATATCTGGCGGA
AACAGCTGAAGGAGGCCATC

Downstream 100 bases:

>100_bases
GAACAACGAGGACATGCGCACGACGCTGGTCCATGCGGGGCGAGGTCCGCAATACCGGGGAAACACGGTCAGCCCGCCCG
TGCACCGCGCGTCGACCTTC

Product: rhodanese-like protein

Products: NA

Alternate protein names: MST; Rhodanese-like protein [H]

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MTDPLVDPAWLTARLDDPLVVPLDCTWYVPEVGISGRARFEEGHVPGAVYVDLDEISDSASPYVNMMCTSETFERVMSAL
GIGSDTHVVVYNANYVSARLWWMFRHFGHEEVSILDGGWARWLAERRPVETGPARPRPLRRFVAGKPKNDIVTAEIVLNA
LRSGDAQVVDVRPRGKFDGTEPTGYPGVLPGHMPGAVNIPWAELFTADAERRFIAPDRFEALLAERGVDADRPIIATCGS
GVTAAILAFHLERIGRHGWHIYDGSWHEWGQRDDLPKETSNG

Sequences:

>Translated_282_residues
MTDPLVDPAWLTARLDDPLVVPLDCTWYVPEVGISGRARFEEGHVPGAVYVDLDEISDSASPYVNMMCTSETFERVMSAL
GIGSDTHVVVYNANYVSARLWWMFRHFGHEEVSILDGGWARWLAERRPVETGPARPRPLRRFVAGKPKNDIVTAEIVLNA
LRSGDAQVVDVRPRGKFDGTEPTGYPGVLPGHMPGAVNIPWAELFTADAERRFIAPDRFEALLAERGVDADRPIIATCGS
GVTAAILAFHLERIGRHGWHIYDGSWHEWGQRDDLPKETSNG
>Mature_281_residues
TDPLVDPAWLTARLDDPLVVPLDCTWYVPEVGISGRARFEEGHVPGAVYVDLDEISDSASPYVNMMCTSETFERVMSALG
IGSDTHVVVYNANYVSARLWWMFRHFGHEEVSILDGGWARWLAERRPVETGPARPRPLRRFVAGKPKNDIVTAEIVLNAL
RSGDAQVVDVRPRGKFDGTEPTGYPGVLPGHMPGAVNIPWAELFTADAERRFIAPDRFEALLAERGVDADRPIIATCGSG
VTAAILAFHLERIGRHGWHIYDGSWHEWGQRDDLPKETSNG

Specific function: Transfers a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. Its participation in detoxification of cyanide may be small. May be involved in the enhancement of serine sensitivity [H]

COG id: COG2897

COG function: function code P; Rhodanese-related sulfurtransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 rhodanese domains [H]

Homologues:

Organism=Homo sapiens, GI194473668, Length=263, Percent_Identity=42.5855513307985, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI61835204, Length=263, Percent_Identity=42.5855513307985, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI194473681, Length=263, Percent_Identity=42.5855513307985, Blast_Score=209, Evalue=3e-54,
Organism=Homo sapiens, GI17402865, Length=288, Percent_Identity=39.9305555555556, Blast_Score=188, Evalue=5e-48,
Organism=Escherichia coli, GI87082121, Length=274, Percent_Identity=40.1459854014599, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI87081967, Length=281, Percent_Identity=25.9786476868327, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17561888, Length=298, Percent_Identity=26.510067114094, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17559150, Length=266, Percent_Identity=28.5714285714286, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71997283, Length=299, Percent_Identity=26.0869565217391, Blast_Score=91, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115534702, Length=247, Percent_Identity=29.1497975708502, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17543836, Length=301, Percent_Identity=22.5913621262458, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17543838, Length=301, Percent_Identity=22.5913621262458, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324825, Length=268, Percent_Identity=29.8507462686567, Blast_Score=131, Evalue=1e-31,

Paralogues:

None

Copy number: 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001763
- InterPro:   IPR001307 [H]

Pfam domain/function: PF00581 Rhodanese [H]

EC number: =2.8.1.2 [H]

Molecular weight: Translated: 31313; Mature: 31181

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00380 RHODANESE_1 ; PS50206 RHODANESE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPLVDPAWLTARLDDPLVVPLDCTWYVPEVGISGRARFEEGHVPGAVYVDLDEISDSA
CCCCCCCCCEEEEECCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCC
SPYVNMMCTSETFERVMSALGIGSDTHVVVYNANYVSARLWWMFRHFGHEEVSILDGGWA
CCEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHH
RWLAERRPVETGPARPRPLRRFVAGKPKNDIVTAEIVLNALRSGDAQVVDVRPRGKFDGT
HHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCC
EPTGYPGVLPGHMPGAVNIPWAELFTADAERRFIAPDRFEALLAERGVDADRPIIATCGS
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCC
GVTAAILAFHLERIGRHGWHIYDGSWHEWGQRDDLPKETSNG
CHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDPLVDPAWLTARLDDPLVVPLDCTWYVPEVGISGRARFEEGHVPGAVYVDLDEISDSA
CCCCCCCCEEEEECCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCC
SPYVNMMCTSETFERVMSALGIGSDTHVVVYNANYVSARLWWMFRHFGHEEVSILDGGWA
CCEEEEEECHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHCCCCEEEEECCHHH
RWLAERRPVETGPARPRPLRRFVAGKPKNDIVTAEIVLNALRSGDAQVVDVRPRGKFDGT
HHHHHCCCCCCCCCCCHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCEEEEECCCCCCCCC
EPTGYPGVLPGHMPGAVNIPWAELFTADAERRFIAPDRFEALLAERGVDADRPIIATCGS
CCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCC
GVTAAILAFHLERIGRHGWHIYDGSWHEWGQRDDLPKETSNG
CHHHHHHHHHHHHHCCCCCEEECCCHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]