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The map label for this gene is aatB [H]

Identifier: 110635952

GI number: 110635952

Start: 3913910

End: 3915145

Strand: Reverse

Name: aatB [H]

Synonym: Meso_3626

Alternate gene names: 110635952

Gene position: 3915145-3913910 (Counterclockwise)

Preceding gene: 110635953

Following gene: 110635950

Centisome position: 88.73

GC content: 62.06

Gene sequence:

>1236_bases
ATGGACACGCAGACGGCTATCTCCGACGCATCGTTCCGGCCCGCAACGCGGGTCGCCTCGCTCGGGGTATCTGAGATCCT
GCAGATCGGCGCACGTGCCGCGCAGATGAAGCGCGCAGGCGAGGACGTCATCGTGCTGGGCGCCGGCGAGCCTGACTTCG
ACACGCCGGAAAATGTGAAGGACGCCGCCACGCGCGCAATGGCGCGCGGGGAGACCAAGTACACCCATCTCGACGGCTCG
CCGGCAATGAAGGAGGCGGTGCGGCACAAATTTCTCTCCGAGAACAGGCTCGACTTCACCACCGATGAGATCACCGTATC
GGCCGGCGCCAAGCAGATCATCTACAACGCCTTCATGGCCACGCTCGATCCCGGCGACGAGGTCATCCTGCCGGCGCCTT
ACTGGACCTCTTATATGGATGTCGTGCGTATCTGCGGCGCAACGCCGGTCGTAGTCGCGTGCGATGCGGAAAACGGCTTC
CGTGCGACCGCTGAGCAGATTGAACGTGCTATCACGCCGCGCACCCGATGGCTTCTTCTCAATTCACCCTCGAATCCCAG
CGGCGCGGCCTATGGCGCGGAAGATTATCGTCCTATCCTCGATATGCTTATGCGGAACCCGCATGTCTGGCTGATGGCGG
ACGATATCTACGAGCATATCGTCTATGACGGGTTCGAATTCGTCACGCCCCTAGCGCTCGAGCCACGGCTCCGCGGCCGC
ACGCTGACGATCAACGGTGTCTCGAAAGCCTATGCCATGACCGGCTGGCGGATCGGCTATGGCGCAGGACCGCAGCCGCT
CGTCAAAGCGATGTCGGTCATTCAGAGCCAGAGCACCTCCAACCCATGTTCCATCAGTCAGGCTGCCGCCATAGAGGCGC
TCACCGGCCCGCAAGAGTTCCTTGCCGAACGCCGCGAGAGCTTCCGCGAGCGACGTGACCTCGTCGTCACTGGCCTGAAT
ACCATCGAAGGTATCGAATGCCGCGTGCCGGAAGGTGCATTCTACGCCTTCGCGGGCTGCGGCGGCCTGCTCGGACGTCG
AACTTCGGACGGCAGTGAAATCGTGAGCGACCGCGATCTGGCGAACTACCTTCTCAAAGACGCCAAAGTGGCGGTCGTCC
CGGGCTCCGCCTTTGGGCTCTCACCCTTCTTCCGCATCTCTTATGCCACCTCCAAATCAGAATTGACGGAAGCATTGCGG
AGAATTGGGGAGGCCTGCCGACGGCTCGTGAGCTAA

Upstream 100 bases:

>100_bases
TGGAAGGCCTATATGCGCCGCGCCACCAACACGGTGAACTATTCGACCGCGCTGCCGCTGGCGCAGGGCGTCAGCTTCGA
TATCGAGTGAGAGCTGGCTG

Downstream 100 bases:

>100_bases
CCCGGTATGGCGAAGCCAGCCGCGCATGCTCTTGGGCTGTCTGCACCAAGTGCTCGGGCGAAACCTCCCGCTATTCCCGG
CTCGGGGGGACGTAGTCCAC

Product: aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MDTQTAISDASFRPATRVASLGVSEILQIGARAAQMKRAGEDVIVLGAGEPDFDTPENVKDAATRAMARGETKYTHLDGS
PAMKEAVRHKFLSENRLDFTTDEITVSAGAKQIIYNAFMATLDPGDEVILPAPYWTSYMDVVRICGATPVVVACDAENGF
RATAEQIERAITPRTRWLLLNSPSNPSGAAYGAEDYRPILDMLMRNPHVWLMADDIYEHIVYDGFEFVTPLALEPRLRGR
TLTINGVSKAYAMTGWRIGYGAGPQPLVKAMSVIQSQSTSNPCSISQAAAIEALTGPQEFLAERRESFRERRDLVVTGLN
TIEGIECRVPEGAFYAFAGCGGLLGRRTSDGSEIVSDRDLANYLLKDAKVAVVPGSAFGLSPFFRISYATSKSELTEALR
RIGEACRRLVS

Sequences:

>Translated_411_residues
MDTQTAISDASFRPATRVASLGVSEILQIGARAAQMKRAGEDVIVLGAGEPDFDTPENVKDAATRAMARGETKYTHLDGS
PAMKEAVRHKFLSENRLDFTTDEITVSAGAKQIIYNAFMATLDPGDEVILPAPYWTSYMDVVRICGATPVVVACDAENGF
RATAEQIERAITPRTRWLLLNSPSNPSGAAYGAEDYRPILDMLMRNPHVWLMADDIYEHIVYDGFEFVTPLALEPRLRGR
TLTINGVSKAYAMTGWRIGYGAGPQPLVKAMSVIQSQSTSNPCSISQAAAIEALTGPQEFLAERRESFRERRDLVVTGLN
TIEGIECRVPEGAFYAFAGCGGLLGRRTSDGSEIVSDRDLANYLLKDAKVAVVPGSAFGLSPFFRISYATSKSELTEALR
RIGEACRRLVS
>Mature_411_residues
MDTQTAISDASFRPATRVASLGVSEILQIGARAAQMKRAGEDVIVLGAGEPDFDTPENVKDAATRAMARGETKYTHLDGS
PAMKEAVRHKFLSENRLDFTTDEITVSAGAKQIIYNAFMATLDPGDEVILPAPYWTSYMDVVRICGATPVVVACDAENGF
RATAEQIERAITPRTRWLLLNSPSNPSGAAYGAEDYRPILDMLMRNPHVWLMADDIYEHIVYDGFEFVTPLALEPRLRGR
TLTINGVSKAYAMTGWRIGYGAGPQPLVKAMSVIQSQSTSNPCSISQAAAIEALTGPQEFLAERRESFRERRDLVVTGLN
TIEGIECRVPEGAFYAFAGCGGLLGRRTSDGSEIVSDRDLANYLLKDAKVAVVPGSAFGLSPFFRISYATSKSELTEALR
RIGEACRRLVS

Specific function: Involved in symbiotic nitrogen fixation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=387, Percent_Identity=26.8733850129199, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI56713256, Length=387, Percent_Identity=26.8733850129199, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI95147551, Length=398, Percent_Identity=25.6281407035176, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881279, Length=398, Percent_Identity=25.6281407035176, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI169881281, Length=336, Percent_Identity=23.8095238095238, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI4507369, Length=315, Percent_Identity=24.4444444444444, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI7705897, Length=316, Percent_Identity=22.1518987341772, Blast_Score=72, Evalue=8e-13,
Organism=Homo sapiens, GI33469970, Length=316, Percent_Identity=22.1518987341772, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1786816, Length=398, Percent_Identity=26.8844221105528, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788722, Length=384, Percent_Identity=28.90625, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788627, Length=358, Percent_Identity=27.9329608938547, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1790797, Length=345, Percent_Identity=26.0869565217391, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567369, Length=396, Percent_Identity=27.5252525252525, Blast_Score=132, Evalue=4e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=390, Percent_Identity=26.1538461538462, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI71994472, Length=390, Percent_Identity=26.1538461538462, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17567663, Length=399, Percent_Identity=24.3107769423559, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71981209, Length=314, Percent_Identity=23.8853503184713, Blast_Score=72, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=359, Percent_Identity=23.6768802228412, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI28573069, Length=424, Percent_Identity=25, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24646114, Length=424, Percent_Identity=25, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573067, Length=424, Percent_Identity=25, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573065, Length=424, Percent_Identity=25, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI18859735, Length=381, Percent_Identity=23.3595800524934, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24641770, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551451, Length=305, Percent_Identity=26.5573770491803, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44763; Mature: 44763

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQTAISDASFRPATRVASLGVSEILQIGARAAQMKRAGEDVIVLGAGEPDFDTPENVK
CCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
DAATRAMARGETKYTHLDGSPAMKEAVRHKFLSENRLDFTTDEITVSAGAKQIIYNAFMA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHH
TLDPGDEVILPAPYWTSYMDVVRICGATPVVVACDAENGFRATAEQIERAITPRTRWLLL
HCCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEE
NSPSNPSGAAYGAEDYRPILDMLMRNPHVWLMADDIYEHIVYDGFEFVTPLALEPRLRGR
ECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHCCCCCCCCCCCC
TLTINGVSKAYAMTGWRIGYGAGPQPLVKAMSVIQSQSTSNPCSISQAAAIEALTGPQEF
EEEEECCHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHH
LAERRESFRERRDLVVTGLNTIEGIECRVPEGAFYAFAGCGGLLGRRTSDGSEIVSDRDL
HHHHHHHHHHHHCEEEECCCCCCCCEEECCCCCEEEEECCCHHHCCCCCCCHHHHHHHHH
ANYLLKDAKVAVVPGSAFGLSPFFRISYATSKSELTEALRRIGEACRRLVS
HHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTQTAISDASFRPATRVASLGVSEILQIGARAAQMKRAGEDVIVLGAGEPDFDTPENVK
CCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHH
DAATRAMARGETKYTHLDGSPAMKEAVRHKFLSENRLDFTTDEITVSAGAKQIIYNAFMA
HHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCEEECCCHHHHHHHHHHH
TLDPGDEVILPAPYWTSYMDVVRICGATPVVVACDAENGFRATAEQIERAITPRTRWLLL
HCCCCCCEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHCCCCEEEEEE
NSPSNPSGAAYGAEDYRPILDMLMRNPHVWLMADDIYEHIVYDGFEFVTPLALEPRLRGR
ECCCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEHHHHHHHHHCCHHHHCCCCCCCCCCCC
TLTINGVSKAYAMTGWRIGYGAGPQPLVKAMSVIQSQSTSNPCSISQAAAIEALTGPQEF
EEEEECCHHHHHHCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCHHHH
LAERRESFRERRDLVVTGLNTIEGIECRVPEGAFYAFAGCGGLLGRRTSDGSEIVSDRDL
HHHHHHHHHHHHCEEEECCCCCCCCEEECCCCCEEEEECCCHHHCCCCCCCHHHHHHHHH
ANYLLKDAKVAVVPGSAFGLSPFFRISYATSKSELTEALRRIGEACRRLVS
HHHHHCCCEEEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11481430 [H]