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The map label for this gene is kipR [H]

Identifier: 110635939

GI number: 110635939

Start: 3898293

End: 3899126

Strand: Reverse

Name: kipR [H]

Synonym: Meso_3613

Alternate gene names: 110635939

Gene position: 3899126-3898293 (Counterclockwise)

Preceding gene: 110635946

Following gene: 110635938

Centisome position: 88.37

GC content: 60.55

Gene sequence:

>834_bases
ATGGAGGAGCCGTCGGGAAGTCAAAGCGTCGAACGTGCCATGCACCTGCTGGCGCTAGTCGCTGAACGGCACAAGAACGG
CGCCACGCTCGCGGAGCTCGTCCGTGCCAGCGGCTTCAAGCAACCCACTACGAGACGGTTGCTGGTCGCATTGATCCGCT
CGGGATTGGTTTCGCAGAACGAAACAACGAGACGCTATCAGCTCGGTGTGTCGGCATATCTTTACGGCACAATCGCTTCG
GATCGCTTTGCCGTGCACACGATGGCCGACGAATCAGTCCGGCGCTTGGCGGAGCGATCGGAGGACACAGCCTTCTTCTG
TTTACGGCAGGGCCTGCATACCCTTTGTATGCAGCGCGAAGAGGGGTTGCACCCCATTCGTTCCCATGTGCTCAACGTCG
GCCAGCGTCATCCGCTCGGCGTGGCCGCTCATGGAATCGCCATCCTGGCGAGCCTGGAGGACCGTGAAATCGACATGATT
GTCGCGGTTCACCGCGACTATTACGCCAGTCATTATCCGATGCTGACGGAGCCGGTCCTGAGGCAGGCGATCGCAGAAAC
GCGAAGGCGCGGCTGCGCGATCAACAGGGGCATTTTCCACGCCGGTGCATGGGCGATCGCAGTCGCCATTCGCGACCATA
CCGGTCGGGTGACTGGCGCCTTGTCGATCGGTGCCATCGAGTCGCGGCTCAACGAAAGCCGCCAGCCGGAAATCATCACT
ATGCTTAAAAGCGAGGCGCGGAAGCTCGAAACGCGTCTCACGGCACTCAGCACCCAGTTTTCCCCTGAAAGTCAAGCGGC
GCAAATGCGCACGTCTACCGCGGTACAGGAATGA

Upstream 100 bases:

>100_bases
AGTAGTTTGTGAAAAAACATGACATGTCAAAAAAAAGTCGTTATAAATCATCGAATTAAAAATTTTACCAGTCCATAATA
TGGACCGTATGGAGGAGTCG

Downstream 100 bases:

>100_bases
TCTGAGCCATGCACGACGCAACAGCCTACGGTAAAGCTCTGAACTCAGCACGCCACCTGACCCATCCGGGTCCGATCGAT
CCGACACGTGTGCGGAGTTA

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Kip operon repressor protein [H]

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MEEPSGSQSVERAMHLLALVAERHKNGATLAELVRASGFKQPTTRRLLVALIRSGLVSQNETTRRYQLGVSAYLYGTIAS
DRFAVHTMADESVRRLAERSEDTAFFCLRQGLHTLCMQREEGLHPIRSHVLNVGQRHPLGVAAHGIAILASLEDREIDMI
VAVHRDYYASHYPMLTEPVLRQAIAETRRRGCAINRGIFHAGAWAIAVAIRDHTGRVTGALSIGAIESRLNESRQPEIIT
MLKSEARKLETRLTALSTQFSPESQAAQMRTSTAVQE

Sequences:

>Translated_277_residues
MEEPSGSQSVERAMHLLALVAERHKNGATLAELVRASGFKQPTTRRLLVALIRSGLVSQNETTRRYQLGVSAYLYGTIAS
DRFAVHTMADESVRRLAERSEDTAFFCLRQGLHTLCMQREEGLHPIRSHVLNVGQRHPLGVAAHGIAILASLEDREIDMI
VAVHRDYYASHYPMLTEPVLRQAIAETRRRGCAINRGIFHAGAWAIAVAIRDHTGRVTGALSIGAIESRLNESRQPEIIT
MLKSEARKLETRLTALSTQFSPESQAAQMRTSTAVQE
>Mature_277_residues
MEEPSGSQSVERAMHLLALVAERHKNGATLAELVRASGFKQPTTRRLLVALIRSGLVSQNETTRRYQLGVSAYLYGTIAS
DRFAVHTMADESVRRLAERSEDTAFFCLRQGLHTLCMQREEGLHPIRSHVLNVGQRHPLGVAAHGIAILASLEDREIDMI
VAVHRDYYASHYPMLTEPVLRQAIAETRRRGCAINRGIFHAGAWAIAVAIRDHTGRVTGALSIGAIESRLNESRQPEIIT
MLKSEARKLETRLTALSTQFSPESQAAQMRTSTAVQE

Specific function: Transcriptional repressor of the kip gene-containing operon [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789999, Length=268, Percent_Identity=26.865671641791, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1786468, Length=228, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87082359, Length=247, Percent_Identity=26.7206477732794, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1786715, Length=248, Percent_Identity=24.5967741935484, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 30730; Mature: 30730

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEPSGSQSVERAMHLLALVAERHKNGATLAELVRASGFKQPTTRRLLVALIRSGLVSQN
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
ETTRRYQLGVSAYLYGTIASDRFAVHTMADESVRRLAERSEDTAFFCLRQGLHTLCMQRE
CCHHHHHHCHHHHEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EGLHPIRSHVLNVGQRHPLGVAAHGIAILASLEDREIDMIVAVHRDYYASHYPMLTEPVL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCEEEEEEEHHHHHHHCCCCHHHHHH
RQAIAETRRRGCAINRGIFHAGAWAIAVAIRDHTGRVTGALSIGAIESRLNESRQPEIIT
HHHHHHHHHHCCCCCCCHHHHCCEEEEEEEECCCCCEEEEEHHHHHHHHHCCCCCCHHHH
MLKSEARKLETRLTALSTQFSPESQAAQMRTSTAVQE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEEPSGSQSVERAMHLLALVAERHKNGATLAELVRASGFKQPTTRRLLVALIRSGLVSQN
CCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCC
ETTRRYQLGVSAYLYGTIASDRFAVHTMADESVRRLAERSEDTAFFCLRQGLHTLCMQRE
CCHHHHHHCHHHHEEEECCCCCEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EGLHPIRSHVLNVGQRHPLGVAAHGIAILASLEDREIDMIVAVHRDYYASHYPMLTEPVL
CCCCHHHHHHHHCCCCCCCCHHHHHHHHEEECCCCCEEEEEEEHHHHHHHCCCCHHHHHH
RQAIAETRRRGCAINRGIFHAGAWAIAVAIRDHTGRVTGALSIGAIESRLNESRQPEIIT
HHHHHHHHHHCCCCCCCHHHHCCEEEEEEEECCCCCEEEEEHHHHHHHHHCCCCCCHHHH
MLKSEARKLETRLTALSTQFSPESQAAQMRTSTAVQE
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377 [H]