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The map label for this gene is ftsY [H]

Identifier: 110635717

GI number: 110635717

Start: 3662700

End: 3664202

Strand: Reverse

Name: ftsY [H]

Synonym: Meso_3389

Alternate gene names: 110635717

Gene position: 3664202-3662700 (Counterclockwise)

Preceding gene: 110635718

Following gene: 110635716

Centisome position: 83.04

GC content: 63.27

Gene sequence:

>1503_bases
ATGGCATTCGGCTTCATCAAGAAAGTCTTTTCCTTCGGCAAGAAGGAGGTCGAGGAGCGGACTGAACCAGCCGAAGCCGC
TTCTGCCGATGCGCCGGCGGTTGAACCGAAGCCCGAAATCCAGCCTGCGACTCCAATCCAGCCGGAACCTGAAAAGCCGG
CCGAAATACCGCCTGCGCCAGAGCCGCCGGCACCGCGCGAACCGACGGAGCCGTCGCCTCCTTCGCCCGAGATACCGCAG
CAGCCCGAGCCGGCGCCTTCTCCCGCGCCTGGCGAGCCGGTCATTCCCAAACCGGAGATTCCCGAACCTTCTCCCGACCT
GCCGCCTGAGCTACCGGAGCCACCGCAGGAGGTGCCGCAACCGGCTCCAGAGCAACCGCCAGGTCCCGCGCCGGAAATTC
CGCAACCCTCGCCGCCTTCGCAGCCCTCCGTTCCGCCTGAGGTTTCTGCGCCTTCTGTAGAGCCAACACCAAGCTCCCGC
TTGGGGGAAGGATCGACCGGCGAGGCTGGGCGGGGCCGCGTCACCGTCTCGACTGCTGTCGAGCGCGCTGGCGAAGCAAA
ATCAGTGTCTGTCGTTGAAGAGCCTCGAAAACCCTGGTTCCAACGGCTGCGCGAAGGGCTCTACCGTTCCTCCCGCGAAC
TGCGCGACAACATTGCCGGTATCTTTCTCAAGCGGAAGCTTGACGAGGATACACTTCAGGATCTGGAAGACGTGCTGCTG
CGCGCCGATCTTGGGCTGGAGACGGCTATGCGCGTCACGGATGCCCTTTCCGTCGGCCGCTACGGGAAGGATATCACCGG
CGCCGAAGTGCAGGCGGTCATGGCTGAAGAGATCGAGAAGGTGCTGAAGCCGGTGGCCCTGCCGCTGGAGCTCGATCTTT
CCCACAAGCCCCATGTAATCCTTGTGGTGGGCGTGAACGGCACAGGCAAGACGACCACGATCGGTAAGCTTGCGGCGAAG
CTCGCCCAGGGTGGGCTCAACGTGATGCTGGCCGCAGGCGATACCTTCCGCGCGGCAGCGATCGAGCAGTTGAAGATCTG
GGGCGAGCGTACCGGCTCTGCCGTAATCTCCTCCAGGCTGGGGGCGGACGCGGCTGGTCTTGCCTACGAGGCCTATGAAA
AGGCGAAGGCTGCGGGCAGCGACGTTCTTATCATCGACACGGCCGGCCGCTTGCAGAACAAGGCCGAGCTGATGGCGGAG
CTGGAAAAGATCGTTCGCGTGCTCGGCAAGCACGATCCGGAAGCGCCTCACACGGTTTTGCAGACGCTCGACGCCACCAC
CGGCCAGAACGCCCTTAATCAGGTCGAAATCTTCCGCAATGTTGCGGGTGTCTCCGGGCTGGTGATGACGAAGCTCGATG
GCACGGCCCGCGGCGGCATCCTGGTGGCGATCGCCGCCAAGCACAAGCTGCCGGTCTATTTTATCGGTGTCGGCGAGGGT
GTCGACGATCTGGAACCTTTTTCGGCAAGCGATTTTGCCAAGGCAATTGCGGGAGTAAGCTGA

Upstream 100 bases:

>100_bases
CAAGCCGGGCGAAATCGTCGAAAGTCTCATTACCGGCCATGACGGCGAACGGCTGACAGCAACGCCGCTGCTGGAAGCGG
CTTGAGGATCTGAGAGGCCA

Downstream 100 bases:

>100_bases
GTGGCGGACGAGAATACGATCTTCGAGCGCGATCCGTCTGATCCCAAGCGCAAGGAAATGAATTCGCTGCTCAAGCTGGC
GCTTGAGCTCGGGCCGCTGC

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MAFGFIKKVFSFGKKEVEERTEPAEAASADAPAVEPKPEIQPATPIQPEPEKPAEIPPAPEPPAPREPTEPSPPSPEIPQ
QPEPAPSPAPGEPVIPKPEIPEPSPDLPPELPEPPQEVPQPAPEQPPGPAPEIPQPSPPSQPSVPPEVSAPSVEPTPSSR
LGEGSTGEAGRGRVTVSTAVERAGEAKSVSVVEEPRKPWFQRLREGLYRSSRELRDNIAGIFLKRKLDEDTLQDLEDVLL
RADLGLETAMRVTDALSVGRYGKDITGAEVQAVMAEEIEKVLKPVALPLELDLSHKPHVILVVGVNGTGKTTTIGKLAAK
LAQGGLNVMLAAGDTFRAAAIEQLKIWGERTGSAVISSRLGADAAGLAYEAYEKAKAAGSDVLIIDTAGRLQNKAELMAE
LEKIVRVLGKHDPEAPHTVLQTLDATTGQNALNQVEIFRNVAGVSGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEG
VDDLEPFSASDFAKAIAGVS

Sequences:

>Translated_500_residues
MAFGFIKKVFSFGKKEVEERTEPAEAASADAPAVEPKPEIQPATPIQPEPEKPAEIPPAPEPPAPREPTEPSPPSPEIPQ
QPEPAPSPAPGEPVIPKPEIPEPSPDLPPELPEPPQEVPQPAPEQPPGPAPEIPQPSPPSQPSVPPEVSAPSVEPTPSSR
LGEGSTGEAGRGRVTVSTAVERAGEAKSVSVVEEPRKPWFQRLREGLYRSSRELRDNIAGIFLKRKLDEDTLQDLEDVLL
RADLGLETAMRVTDALSVGRYGKDITGAEVQAVMAEEIEKVLKPVALPLELDLSHKPHVILVVGVNGTGKTTTIGKLAAK
LAQGGLNVMLAAGDTFRAAAIEQLKIWGERTGSAVISSRLGADAAGLAYEAYEKAKAAGSDVLIIDTAGRLQNKAELMAE
LEKIVRVLGKHDPEAPHTVLQTLDATTGQNALNQVEIFRNVAGVSGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEG
VDDLEPFSASDFAKAIAGVS
>Mature_499_residues
AFGFIKKVFSFGKKEVEERTEPAEAASADAPAVEPKPEIQPATPIQPEPEKPAEIPPAPEPPAPREPTEPSPPSPEIPQQ
PEPAPSPAPGEPVIPKPEIPEPSPDLPPELPEPPQEVPQPAPEQPPGPAPEIPQPSPPSQPSVPPEVSAPSVEPTPSSRL
GEGSTGEAGRGRVTVSTAVERAGEAKSVSVVEEPRKPWFQRLREGLYRSSRELRDNIAGIFLKRKLDEDTLQDLEDVLLR
ADLGLETAMRVTDALSVGRYGKDITGAEVQAVMAEEIEKVLKPVALPLELDLSHKPHVILVVGVNGTGKTTTIGKLAAKL
AQGGLNVMLAAGDTFRAAAIEQLKIWGERTGSAVISSRLGADAAGLAYEAYEKAKAAGSDVLIIDTAGRLQNKAELMAEL
EKIVRVLGKHDPEAPHTVLQTLDATTGQNALNQVEIFRNVAGVSGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEGV
DDLEPFSASDFAKAIAGVS

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=204, Percent_Identity=34.3137254901961, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4507215, Length=204, Percent_Identity=34.3137254901961, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI295424842, Length=302, Percent_Identity=28.1456953642384, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI23308697, Length=302, Percent_Identity=28.1456953642384, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI89061728, Length=133, Percent_Identity=32.3308270676692, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1789874, Length=311, Percent_Identity=47.2668810289389, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1788963, Length=309, Percent_Identity=34.3042071197411, Blast_Score=125, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI17539958, Length=273, Percent_Identity=28.9377289377289, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193206261, Length=211, Percent_Identity=35.0710900473934, Blast_Score=103, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6325345, Length=205, Percent_Identity=36.0975609756098, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6320498, Length=222, Percent_Identity=27.9279279279279, Blast_Score=88, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24641198, Length=294, Percent_Identity=27.891156462585, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17647949, Length=230, Percent_Identity=30.8695652173913, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI221472639, Length=154, Percent_Identity=31.8181818181818, Blast_Score=65, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 52766; Mature: 52635

Theoretical pI: Translated: 4.57; Mature: 4.57

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFGFIKKVFSFGKKEVEERTEPAEAASADAPAVEPKPEIQPATPIQPEPEKPAEIPPAP
CCHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPPAPREPTEPSPPSPEIPQQPEPAPSPAPGEPVIPKPEIPEPSPDLPPELPEPPQEVPQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PAPEQPPGPAPEIPQPSPPSQPSVPPEVSAPSVEPTPSSRLGEGSTGEAGRGRVTVSTAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHH
ERAGEAKSVSVVEEPRKPWFQRLREGLYRSSRELRDNIAGIFLKRKLDEDTLQDLEDVLL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RADLGLETAMRVTDALSVGRYGKDITGAEVQAVMAEEIEKVLKPVALPLELDLSHKPHVI
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
LVVGVNGTGKTTTIGKLAAKLAQGGLNVMLAAGDTFRAAAIEQLKIWGERTGSAVISSRL
EEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHC
GADAAGLAYEAYEKAKAAGSDVLIIDTAGRLQNKAELMAELEKIVRVLGKHDPEAPHTVL
CCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QTLDATTGQNALNQVEIFRNVAGVSGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEG
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCC
VDDLEPFSASDFAKAIAGVS
CCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure 
AFGFIKKVFSFGKKEVEERTEPAEAASADAPAVEPKPEIQPATPIQPEPEKPAEIPPAP
CHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
EPPAPREPTEPSPPSPEIPQQPEPAPSPAPGEPVIPKPEIPEPSPDLPPELPEPPQEVPQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCC
PAPEQPPGPAPEIPQPSPPSQPSVPPEVSAPSVEPTPSSRLGEGSTGEAGRGRVTVSTAV
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEHHHHH
ERAGEAKSVSVVEEPRKPWFQRLREGLYRSSRELRDNIAGIFLKRKLDEDTLQDLEDVLL
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RADLGLETAMRVTDALSVGRYGKDITGAEVQAVMAEEIEKVLKPVALPLELDLSHKPHVI
HHCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCEE
LVVGVNGTGKTTTIGKLAAKLAQGGLNVMLAAGDTFRAAAIEQLKIWGERTGSAVISSRL
EEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHC
GADAAGLAYEAYEKAKAAGSDVLIIDTAGRLQNKAELMAELEKIVRVLGKHDPEAPHTVL
CCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
QTLDATTGQNALNQVEIFRNVAGVSGLVMTKLDGTARGGILVAIAAKHKLPVYFIGVGEG
HHHHCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCC
VDDLEPFSASDFAKAIAGVS
CCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]