Click here to switch to the map view.

The map label for this gene is frc [H]

Identifier: 110635614

GI number: 110635614

Start: 3552040

End: 3553245

Strand: Reverse

Name: frc [H]

Synonym: Meso_3286

Alternate gene names: 110635614

Gene position: 3553245-3552040 (Counterclockwise)

Preceding gene: 110635629

Following gene: 110635601

Centisome position: 80.53

GC content: 63.93

Gene sequence:

>1206_bases
ATGACTGACATCAAGATTGCTCCCGGCCCGCTGTCCGGAATTCGTGTGCTGGACTTCACGAGTGTGCTTTCCGGCCCCTA
CTGCACGCGTCTGCTGGCGGATCTCGGCGCCGAAGTGCTGAAGATCGAGCCGCCGGAGGGCGATCACAAACGGCTGGTTC
CACCGCTGCGCAGCGGCCATGGATCCACCTTCGCTCACGTGAACAGCGGGAAGAAGAGCGTGGTGCTGGACCTGAAGTCA
CCGGAGGGCGCACAGGCGGCATGCGAGCTTTCTGCCCGGTCAGCGGTCGTGGTACAGAACTGGCGGCCGGACGTGGCGGT
CCGGCTCGGGCTGGATTATGCGGCGCTCTCGAAGGAAAACCCTGCCCTCGTCTATTGTGCGATCTCGGGCTATGGTCAGG
AAGGCGAAAGGGCCATGCGCCCCGCCTATGCGCCGATCGTGCACGCCGCAAGCGGCTACGAACTGGCCCAGATGCAATAT
CAGCCCGGCGCGACAGAGCCAGCGGCAACCGGTATCTTCATCGCCGATATTTTCGCCGGCATGTCGGCCTTCGGCGCAAT
TAACGCTGCCCTGCTGCGCCGGCAGAGGACGGGAAGGGGTCAGTTCATCGACGTTTCGATGTATGATGGAATGCTCAACC
TGCTCATGTTCGAATGGCACCAGGCGCAGTTTTTCGAGGTGCCTCGAAGGATTTATCCGCCGCTGCGCGCCAGCGACGGC
TTCATCGTGGTAGCGCCGGTCACGCAGCGCAATTTTCACGCACTGGCAGATTGCATCGGCAGGCCGGAGATCAAGAGCGA
TCCGAGATTTTCGAGCCCCTCGGCGCGCGTGAGCAACTGGCAGGAGCTGATGGTGCTCGCGGCGGAATGGGTGCGCGAGC
GCACCGCGCAAGAGTGCGAGGAACTGATGACAGCCCATCAGGTGCCCTGCGCGCGCTACCGCACGGTCGCCGAATCGCTC
AGCGATCCCGCGCTTGCCGAACGGGGCTCTTTGGCCACCGTCGTTGATGGCGCGGGCGATGTGCTGATCCCAACCGCACC
TTGGCAGATGCCCGGTGTGGACGCGCGCCCCCGCACGGATGTACCGGCGCTCGGCGCCTCGACGGAAGAGGTTTTGTCGG
AGCTTCTGGGCTATGGTAAGGAGACAATCCGCGCCTGCCAGGGCTCTCGCACGAAAGAGCCGCCACAGGTCGCGCCCGTG
AAGTGA

Upstream 100 bases:

>100_bases
AGATTGGCTTGGAACGGCAATTTGGCATGGCCGGGGCAATATGTATTGTCCCAAACGTAACCTGAATGTACCGGCCCGCG
GAGATGGAATTGGAAACTGA

Downstream 100 bases:

>100_bases
AGCAGGAGCGGGCGTGCTCTCGCGGCCTACTCGCTTGAAAACCTCGGGCTTCAGCGGCCGCGGAATTCGGGCTTTCGCTT
TTCCTTGAAGGCAGCTACCG

Product: L-carnitine dehydratase/bile acid-inducible protein F

Products: NA

Alternate protein names: Formyl-CoA transferase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTDIKIAPGPLSGIRVLDFTSVLSGPYCTRLLADLGAEVLKIEPPEGDHKRLVPPLRSGHGSTFAHVNSGKKSVVLDLKS
PEGAQAACELSARSAVVVQNWRPDVAVRLGLDYAALSKENPALVYCAISGYGQEGERAMRPAYAPIVHAASGYELAQMQY
QPGATEPAATGIFIADIFAGMSAFGAINAALLRRQRTGRGQFIDVSMYDGMLNLLMFEWHQAQFFEVPRRIYPPLRASDG
FIVVAPVTQRNFHALADCIGRPEIKSDPRFSSPSARVSNWQELMVLAAEWVRERTAQECEELMTAHQVPCARYRTVAESL
SDPALAERGSLATVVDGAGDVLIPTAPWQMPGVDARPRTDVPALGASTEEVLSELLGYGKETIRACQGSRTKEPPQVAPV
K

Sequences:

>Translated_401_residues
MTDIKIAPGPLSGIRVLDFTSVLSGPYCTRLLADLGAEVLKIEPPEGDHKRLVPPLRSGHGSTFAHVNSGKKSVVLDLKS
PEGAQAACELSARSAVVVQNWRPDVAVRLGLDYAALSKENPALVYCAISGYGQEGERAMRPAYAPIVHAASGYELAQMQY
QPGATEPAATGIFIADIFAGMSAFGAINAALLRRQRTGRGQFIDVSMYDGMLNLLMFEWHQAQFFEVPRRIYPPLRASDG
FIVVAPVTQRNFHALADCIGRPEIKSDPRFSSPSARVSNWQELMVLAAEWVRERTAQECEELMTAHQVPCARYRTVAESL
SDPALAERGSLATVVDGAGDVLIPTAPWQMPGVDARPRTDVPALGASTEEVLSELLGYGKETIRACQGSRTKEPPQVAPV
K
>Mature_400_residues
TDIKIAPGPLSGIRVLDFTSVLSGPYCTRLLADLGAEVLKIEPPEGDHKRLVPPLRSGHGSTFAHVNSGKKSVVLDLKSP
EGAQAACELSARSAVVVQNWRPDVAVRLGLDYAALSKENPALVYCAISGYGQEGERAMRPAYAPIVHAASGYELAQMQYQ
PGATEPAATGIFIADIFAGMSAFGAINAALLRRQRTGRGQFIDVSMYDGMLNLLMFEWHQAQFFEVPRRIYPPLRASDGF
IVVAPVTQRNFHALADCIGRPEIKSDPRFSSPSARVSNWQELMVLAAEWVRERTAQECEELMTAHQVPCARYRTVAESLS
DPALAERGSLATVVDGAGDVLIPTAPWQMPGVDARPRTDVPALGASTEEVLSELLGYGKETIRACQGSRTKEPPQVAPVK

Specific function: Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate [H]

COG id: COG1804

COG function: function code C; Predicted acyl-CoA transferases/carnitine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CaiB/BaiF CoA-transferase family [H]

Homologues:

Organism=Homo sapiens, GI300863128, Length=404, Percent_Identity=29.9504950495049, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI300863124, Length=430, Percent_Identity=29.3023255813954, Blast_Score=170, Evalue=2e-42,
Organism=Homo sapiens, GI13376042, Length=430, Percent_Identity=26.7441860465116, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI300863126, Length=391, Percent_Identity=27.6214833759591, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI42794625, Length=403, Percent_Identity=29.7766749379653, Blast_Score=128, Evalue=1e-29,
Organism=Homo sapiens, GI266456254, Length=399, Percent_Identity=29.8245614035088, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI266458393, Length=264, Percent_Identity=32.1969696969697, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI266458397, Length=258, Percent_Identity=32.1705426356589, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI42822893, Length=125, Percent_Identity=36, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI266458395, Length=125, Percent_Identity=36, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI87082093, Length=358, Percent_Identity=31.0055865921788, Blast_Score=165, Evalue=5e-42,
Organism=Escherichia coli, GI1788717, Length=416, Percent_Identity=28.125, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786222, Length=408, Percent_Identity=26.9607843137255, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32564160, Length=309, Percent_Identity=28.1553398058252, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI115535051, Length=307, Percent_Identity=27.3615635179153, Blast_Score=91, Evalue=7e-19,
Organism=Drosophila melanogaster, GI24648431, Length=393, Percent_Identity=32.3155216284987, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI24585488, Length=204, Percent_Identity=36.2745098039216, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003673
- InterPro:   IPR017659 [H]

Pfam domain/function: PF02515 CoA_transf_3 [H]

EC number: =2.8.3.16 [H]

Molecular weight: Translated: 43380; Mature: 43249

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIKIAPGPLSGIRVLDFTSVLSGPYCTRLLADLGAEVLKIEPPEGDHKRLVPPLRSGH
CCCCEECCCCCCCEEEEEHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCC
GSTFAHVNSGKKSVVLDLKSPEGAQAACELSARSAVVVQNWRPDVAVRLGLDYAALSKEN
CCEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHCCCC
PALVYCAISGYGQEGERAMRPAYAPIVHAASGYELAQMQYQPGATEPAATGIFIADIFAG
CEEEEEEECCCCCCCHHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
MSAFGAINAALLRRQRTGRGQFIDVSMYDGMLNLLMFEWHQAQFFEVPRRIYPPLRASDG
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FIVVAPVTQRNFHALADCIGRPEIKSDPRFSSPSARVSNWQELMVLAAEWVRERTAQECE
EEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMTAHQVPCARYRTVAESLSDPALAERGSLATVVDGAGDVLIPTAPWQMPGVDARPRTD
HHHHHHCCCHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCC
VPALGASTEEVLSELLGYGKETIRACQGSRTKEPPQVAPVK
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TDIKIAPGPLSGIRVLDFTSVLSGPYCTRLLADLGAEVLKIEPPEGDHKRLVPPLRSGH
CCCEECCCCCCCEEEEEHHHHHCCHHHHHHHHHCCCEEEEECCCCCCCCCCCCHHHCCC
GSTFAHVNSGKKSVVLDLKSPEGAQAACELSARSAVVVQNWRPDVAVRLGLDYAALSKEN
CCEEEEECCCCEEEEEEECCCCCCHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHCCCC
PALVYCAISGYGQEGERAMRPAYAPIVHAASGYELAQMQYQPGATEPAATGIFIADIFAG
CEEEEEEECCCCCCCHHHHCCCHHHHHCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHHH
MSAFGAINAALLRRQRTGRGQFIDVSMYDGMLNLLMFEWHQAQFFEVPRRIYPPLRASDG
HHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FIVVAPVTQRNFHALADCIGRPEIKSDPRFSSPSARVSNWQELMVLAAEWVRERTAQECE
EEEEEECCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ELMTAHQVPCARYRTVAESLSDPALAERGSLATVVDGAGDVLIPTAPWQMPGVDARPRTD
HHHHHHCCCHHHHHHHHHHCCCCHHHHCCCEEEEECCCCCEEECCCCCCCCCCCCCCCCC
VPALGASTEEVLSELLGYGKETIRACQGSRTKEPPQVAPVK
CCCCCCCHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]