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The map label for this gene is qor [C]

Identifier: 110635276

GI number: 110635276

Start: 3206031

End: 3207038

Strand: Reverse

Name: qor [C]

Synonym: Meso_2947

Alternate gene names: 110635276

Gene position: 3207038-3206031 (Counterclockwise)

Preceding gene: 110635277

Following gene: 110635275

Centisome position: 72.68

GC content: 61.01

Gene sequence:

>1008_bases
ATGAAAGCGGTCGTCAGCCACGAATTCGCACCGTTCAGGCACGTTCTAGTCGAGCAGATGCCCGACCCTGTGCCAGGGAC
TGGCGAGCTTGTGATCGACATCGAAGCCTCCGATGTAAATTTTCCCGATATCCTTCAGATCGAAGGAATGTATCAGGTGC
GCGCTCCGCGTCCGTTCATTCCGGGCCTTGGCGCGATTGGCCGCGTATCCGCTGTCGGACCGGAAGTGGCAGATTTCGTC
TTGGGCCAAAGAGTGCTCGCTCTGCCCGATGGCGCCCATGCGGGAACCCATGCAGAGAAAGCGCGCGTGCCTGCTCGCTT
TTGCTTCATTGCACCAGAAGACGTGCCCAGCGACATCGGGGCCGCACTCGGCCTTGCCTATCAGACGGCTCATGCGGCGC
TGACGCGGCGCGCGTTGCTGCAACCCGGTGAGAGCGTTCTGGTGCTAGGGGCGACCGGTGGAATCGGAATGGCCGCTATC
CAACTTGCCCGCGCCTTGGGCGCAAGCTGTGTGATTGCTGCGACGCGAGGCAAGGAAGGCACGGAAATAGCCAGGGAGAT
GGGTGCCGATCATGTGATCGACACAAGGCAAGGAGAACTCAAAGAGGTCCTGCGCCACGGCGTAAGATCGGTGACGGGCG
GAGCCGGTGTTGATGTGGTGATCGATCCGGTCGGCGGAAGTGTGGGCGAAGCAGCGTTACGCACGCTTGCATGGCACGGC
CGGCTCGTGGTGGTGGGCTTTGCTTCGGGCGACATCCCTTCATTCAAGGGCAATTATCTGTTGATCAAGGGCATCAGCGT
CTGCGGCATGCAGTGGACCGATTACCAGGCTCGCGATCCGCAGGGCATTCGCGACGCACAGGCAAAGATCTTCGATCTGT
GGCGCAGCGGCCGGCTTTCGCCGCGAATTTCGCGCCGGTTGCCGCTATCGCGCGCTGCCGAGGCGTTTGAGGCAGTCGCG
ATGGGCGATGCACGTGGAAAGATAATTCTACTGCCGGAAACTCATTGA

Upstream 100 bases:

>100_bases
CCGTGAGCGGAGAGATCTACCGGCTGACGGGGCTTCCGGCATATGCGCCGGCGCGGCGCGCCGTGGTCGCTGCCGATCGC
GCGGCACAACGAGGCCCCGT

Downstream 100 bases:

>100_bases
AAGAAGAATGATGACGGAAATTCCTAATACTTGCAGCATTGGCGTCATCGGTGCGGGCACCATGGGCGCGGGCATCGCGC
AGGTTGCGGCGGCTGCCGGG

Product: zinc-binding alcohol dehydrogenase

Products: NA

Alternate protein names: Acryloyl-CoA reductase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKAVVSHEFAPFRHVLVEQMPDPVPGTGELVIDIEASDVNFPDILQIEGMYQVRAPRPFIPGLGAIGRVSAVGPEVADFV
LGQRVLALPDGAHAGTHAEKARVPARFCFIAPEDVPSDIGAALGLAYQTAHAALTRRALLQPGESVLVLGATGGIGMAAI
QLARALGASCVIAATRGKEGTEIAREMGADHVIDTRQGELKEVLRHGVRSVTGGAGVDVVIDPVGGSVGEAALRTLAWHG
RLVVVGFASGDIPSFKGNYLLIKGISVCGMQWTDYQARDPQGIRDAQAKIFDLWRSGRLSPRISRRLPLSRAAEAFEAVA
MGDARGKIILLPETH

Sequences:

>Translated_335_residues
MKAVVSHEFAPFRHVLVEQMPDPVPGTGELVIDIEASDVNFPDILQIEGMYQVRAPRPFIPGLGAIGRVSAVGPEVADFV
LGQRVLALPDGAHAGTHAEKARVPARFCFIAPEDVPSDIGAALGLAYQTAHAALTRRALLQPGESVLVLGATGGIGMAAI
QLARALGASCVIAATRGKEGTEIAREMGADHVIDTRQGELKEVLRHGVRSVTGGAGVDVVIDPVGGSVGEAALRTLAWHG
RLVVVGFASGDIPSFKGNYLLIKGISVCGMQWTDYQARDPQGIRDAQAKIFDLWRSGRLSPRISRRLPLSRAAEAFEAVA
MGDARGKIILLPETH
>Mature_335_residues
MKAVVSHEFAPFRHVLVEQMPDPVPGTGELVIDIEASDVNFPDILQIEGMYQVRAPRPFIPGLGAIGRVSAVGPEVADFV
LGQRVLALPDGAHAGTHAEKARVPARFCFIAPEDVPSDIGAALGLAYQTAHAALTRRALLQPGESVLVLGATGGIGMAAI
QLARALGASCVIAATRGKEGTEIAREMGADHVIDTRQGELKEVLRHGVRSVTGGAGVDVVIDPVGGSVGEAALRTLAWHG
RLVVVGFASGDIPSFKGNYLLIKGISVCGMQWTDYQARDPQGIRDAQAKIFDLWRSGRLSPRISRRLPLSRAAEAFEAVA
MGDARGKIILLPETH

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the acryloyl- CoA dependent NADPH oxidation and formation of propionyl-CoA. Inactive towards 3-hydroxypropionyl-CoA, NADH and crotonyl-CoA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=320, Percent_Identity=29.375, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI194239674, Length=333, Percent_Identity=30.9309309309309, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI13236495, Length=333, Percent_Identity=30.9309309309309, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI22538446, Length=328, Percent_Identity=29.5731707317073, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI22538444, Length=328, Percent_Identity=29.5731707317073, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI194239676, Length=333, Percent_Identity=29.1291291291291, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI28557745, Length=357, Percent_Identity=29.6918767507003, Blast_Score=96, Evalue=3e-20,
Organism=Homo sapiens, GI24308257, Length=353, Percent_Identity=26.3456090651558, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI67078404, Length=295, Percent_Identity=26.7796610169492, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI67078406, Length=291, Percent_Identity=27.1477663230241, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI47519420, Length=339, Percent_Identity=27.1386430678466, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI41872631, Length=310, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI197927207, Length=199, Percent_Identity=31.6582914572864, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1790485, Length=315, Percent_Identity=29.2063492063492, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790045, Length=344, Percent_Identity=25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1789651, Length=230, Percent_Identity=30.4347826086957, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71987554, Length=361, Percent_Identity=21.8836565096953, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI212642053, Length=304, Percent_Identity=30.2631578947368, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=330, Percent_Identity=28.1818181818182, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45550423, Length=304, Percent_Identity=25, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.3.1.84 [H]

Molecular weight: Translated: 35387; Mature: 35387

Theoretical pI: Translated: 7.02; Mature: 7.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVVSHEFAPFRHVLVEQMPDPVPGTGELVIDIEASDVNFPDILQIEGMYQVRAPRPFI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEECCEEEECCCCCCC
PGLGAIGRVSAVGPEVADFVLGQRVLALPDGAHAGTHAEKARVPARFCFIAPEDVPSDIG
CCCCCCCCHHHCCHHHHHHHHCCEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCHHHH
AALGLAYQTAHAALTRRALLQPGESVLVLGATGGIGMAAIQLARALGASCVIAATRGKEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCH
TEIAREMGADHVIDTRQGELKEVLRHGVRSVTGGAGVDVVIDPVGGSVGEAALRTLAWHG
HHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
RLVVVGFASGDIPSFKGNYLLIKGISVCGMQWTDYQARDPQGIRDAQAKIFDLWRSGRLS
EEEEEEECCCCCCCCCCCEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
PRISRRLPLSRAAEAFEAVAMGDARGKIILLPETH
CHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCC
>Mature Secondary Structure
MKAVVSHEFAPFRHVLVEQMPDPVPGTGELVIDIEASDVNFPDILQIEGMYQVRAPRPFI
CCCCCCCCCHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCEEEECCEEEECCCCCCC
PGLGAIGRVSAVGPEVADFVLGQRVLALPDGAHAGTHAEKARVPARFCFIAPEDVPSDIG
CCCCCCCCHHHCCHHHHHHHHCCEEEECCCCCCCCCCHHHHCCCEEEEEECCCCCCHHHH
AALGLAYQTAHAALTRRALLQPGESVLVLGATGGIGMAAIQLARALGASCVIAATRGKEG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCH
TEIAREMGADHVIDTRQGELKEVLRHGVRSVTGGAGVDVVIDPVGGSVGEAALRTLAWHG
HHHHHHCCCCCEECCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHCC
RLVVVGFASGDIPSFKGNYLLIKGISVCGMQWTDYQARDPQGIRDAQAKIFDLWRSGRLS
EEEEEEECCCCCCCCCCCEEEEEECEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
PRISRRLPLSRAAEAFEAVAMGDARGKIILLPETH
CHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11572479 [H]