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The map label for this gene is ddpA [H]

Identifier: 110634967

GI number: 110634967

Start: 2842419

End: 2843966

Strand: Reverse

Name: ddpA [H]

Synonym: Meso_2633

Alternate gene names: 110634967

Gene position: 2843966-2842419 (Counterclockwise)

Preceding gene: 110634968

Following gene: 110634966

Centisome position: 64.45

GC content: 58.91

Gene sequence:

>1548_bases
ATGGGACCAAAGCTTTCACGCAGGCATTTCGTAGGAGGAGCGGCCGCACTTTCCGCGCTTGCTCCGCTTGGCATCGTGCC
GGCCTTTTCGCAGGAGCATCAGTCGTTCATCGCGCGCGTCGATCGTGACGTTGAAAATCTCGATCCGGCATTCCGCACCA
GCCTAACCGACTCCAATGTCATCAGGGTGGTCTATCAGCGCCTCATCGACTACAACGTGGGCGCCTATGGCTGGCAGCTG
GACGCTGCCGAAGCGATCGAGCAAAAGTCTGATCTGGAAATCACCTTTAGGCTCAAGCAGGGCATCATGTTCACCGGCGG
CTATGGTGAAATGACCGCCGACGACGTGAAGTTCTCCTTGGAGCGCTTTGCTTTCCCTGACGCCGAGGGGCGCGTTTCGA
GCTACCGCCAGGATTGGGCCGATCTCAAAGAGGTGGTGGTCCACGATAAATATTCCGGCAGCATCATTTTCGAAAGGCCT
GCCCCCAACATCTGGCAATCGGCCTTGCCGCATGCGTCTGGCGCAATCGTATCGCGCAAGGCGGTGGAAAAATTCGGTGC
CCAGTTCGGCCGCAACCCAGTGGGCTCGGGACGTTATGAGGTCGTTTCGTTCAGCGCCCAGGACGGCGTGGTCCTCAAGC
GCAATCCGCTTTTCCTGGATACGCCGGGCGAATTCGAGAGCTTTACCGTCAGGTTCATATCGAACGTCAAGACGGCCCAG
CTTGCCGTCGAGGCCGGTGAAATTGACTTCACTCAGGTTCCCCTGACCACCGTGCCGGAGCTCGAGCGCTCGGGTCGGGT
TGCGGTAAGCGTCATCCCCACGCAGAAGTTCATCTGGCTCGGTCTTAATACGGAGTCGCCCAAGCTGGCCGATATCAAGG
TCCGGCAAGCCATTCGCGCGGCAGTGAATATCGACGAGGTGCTGCTGGGAGCCTATCAGGGTAAGGCGCCGCGTCTCAAC
ACTCTGCTTCCCGCTGGCCTTGCCGGCCACTGGGCTGAGGCGCCCGTCTACACTCAGGATCTCCAGCAAGCACAGGCATT
GCTCGCCGAAGCCAATGTGTCCGGTCCCTTGAAGGTCAAGCTGACGGTTTTGAACGAGCCGGTGTTCAATACCATAGCTC
TCATCGTCCAGGCGCAGCTTGCTGCCGCGGGCATAGAGGTGGAAATCGATCAGCGGGAAGGCGGTAGCTTCTGGTCGGCG
GGCAAGGACGAATCGGGCGAGAACATGGAGCTCTACATCACGAGCTTCAATACCTCGGTTGCCCCGGTCGCCAATACGCG
CTGGTTCCTGCCCAACCAGATCGGCGACTGGAACTGGAGCCGCTGGAACAGCCCCGAATTCGAAGAACTCTACGACAGCA
TCAGCGTGGATTTCGATATCGATTCCCGCTCCGCGAAGTTGATCGAAATGCAGCGGCTGATGGACGAGTCGGCTGCCTTT
ATCTGGCTGACCAGCGATGTCGTGGCCTATGCGCATCAGACCTGGCTCGTACCCATGATTCTTCCCAATGGCGTCGACTG
CCAATACGCCTATTTCAGGCGCGCCTAA

Upstream 100 bases:

>100_bases
CAGGAGCACGCGGTTCGATGCCATTTTCCATTTTCGCTGTCCGCCCAATAGGTCTGGGACAACGCCAGCGGACAGCCAAA
GCGAGGGACAGGAGAAACTA

Downstream 100 bases:

>100_bases
CAATCACTGCCACCAAGCTGCCGGGGCTTCACGTCTGAAGAGCACCGGCCAAGAACCGGATCAATATGTCGAGTTCTGAC
AAAGACCTAGTTCTGGGCAC

Product: twin-arginine translocation pathway signal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MGPKLSRRHFVGGAAALSALAPLGIVPAFSQEHQSFIARVDRDVENLDPAFRTSLTDSNVIRVVYQRLIDYNVGAYGWQL
DAAEAIEQKSDLEITFRLKQGIMFTGGYGEMTADDVKFSLERFAFPDAEGRVSSYRQDWADLKEVVVHDKYSGSIIFERP
APNIWQSALPHASGAIVSRKAVEKFGAQFGRNPVGSGRYEVVSFSAQDGVVLKRNPLFLDTPGEFESFTVRFISNVKTAQ
LAVEAGEIDFTQVPLTTVPELERSGRVAVSVIPTQKFIWLGLNTESPKLADIKVRQAIRAAVNIDEVLLGAYQGKAPRLN
TLLPAGLAGHWAEAPVYTQDLQQAQALLAEANVSGPLKVKLTVLNEPVFNTIALIVQAQLAAAGIEVEIDQREGGSFWSA
GKDESGENMELYITSFNTSVAPVANTRWFLPNQIGDWNWSRWNSPEFEELYDSISVDFDIDSRSAKLIEMQRLMDESAAF
IWLTSDVVAYAHQTWLVPMILPNGVDCQYAYFRRA

Sequences:

>Translated_515_residues
MGPKLSRRHFVGGAAALSALAPLGIVPAFSQEHQSFIARVDRDVENLDPAFRTSLTDSNVIRVVYQRLIDYNVGAYGWQL
DAAEAIEQKSDLEITFRLKQGIMFTGGYGEMTADDVKFSLERFAFPDAEGRVSSYRQDWADLKEVVVHDKYSGSIIFERP
APNIWQSALPHASGAIVSRKAVEKFGAQFGRNPVGSGRYEVVSFSAQDGVVLKRNPLFLDTPGEFESFTVRFISNVKTAQ
LAVEAGEIDFTQVPLTTVPELERSGRVAVSVIPTQKFIWLGLNTESPKLADIKVRQAIRAAVNIDEVLLGAYQGKAPRLN
TLLPAGLAGHWAEAPVYTQDLQQAQALLAEANVSGPLKVKLTVLNEPVFNTIALIVQAQLAAAGIEVEIDQREGGSFWSA
GKDESGENMELYITSFNTSVAPVANTRWFLPNQIGDWNWSRWNSPEFEELYDSISVDFDIDSRSAKLIEMQRLMDESAAF
IWLTSDVVAYAHQTWLVPMILPNGVDCQYAYFRRA
>Mature_514_residues
GPKLSRRHFVGGAAALSALAPLGIVPAFSQEHQSFIARVDRDVENLDPAFRTSLTDSNVIRVVYQRLIDYNVGAYGWQLD
AAEAIEQKSDLEITFRLKQGIMFTGGYGEMTADDVKFSLERFAFPDAEGRVSSYRQDWADLKEVVVHDKYSGSIIFERPA
PNIWQSALPHASGAIVSRKAVEKFGAQFGRNPVGSGRYEVVSFSAQDGVVLKRNPLFLDTPGEFESFTVRFISNVKTAQL
AVEAGEIDFTQVPLTTVPELERSGRVAVSVIPTQKFIWLGLNTESPKLADIKVRQAIRAAVNIDEVLLGAYQGKAPRLNT
LLPAGLAGHWAEAPVYTQDLQQAQALLAEANVSGPLKVKLTVLNEPVFNTIALIVQAQLAAAGIEVEIDQREGGSFWSAG
KDESGENMELYITSFNTSVAPVANTRWFLPNQIGDWNWSRWNSPEFEELYDSISVDFDIDSRSAKLIEMQRLMDESAAFI
WLTSDVVAYAHQTWLVPMILPNGVDCQYAYFRRA

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=458, Percent_Identity=24.4541484716157, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI1789966, Length=497, Percent_Identity=22.7364185110664, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787052, Length=432, Percent_Identity=22.6851851851852, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787495, Length=522, Percent_Identity=22.2222222222222, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57049; Mature: 56918

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGPKLSRRHFVGGAAALSALAPLGIVPAFSQEHQSFIARVDRDVENLDPAFRTSLTDSNV
CCCCCCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCHH
IRVVYQRLIDYNVGAYGWQLDAAEAIEQKSDLEITFRLKQGIMFTGGYGEMTADDVKFSL
HHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCEEEEEEECCEEEECCCCCCCHHHHHHHH
ERFAFPDAEGRVSSYRQDWADLKEVVVHDKYSGSIIFERPAPNIWQSALPHASGAIVSRK
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCCCCHHHHH
AVEKFGAQFGRNPVGSGRYEVVSFSAQDGVVLKRNPLFLDTPGEFESFTVRFISNVKTAQ
HHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCEEEECCCCCHHHHHHHHHCCCEEE
LAVEAGEIDFTQVPLTTVPELERSGRVAVSVIPTQKFIWLGLNTESPKLADIKVRQAIRA
EEEECCCCEEEECCCCCCCCHHCCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHH
AVNIDEVLLGAYQGKAPRLNTLLPAGLAGHWAEAPVYTQDLQQAQALLAEANVSGPLKVK
HCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
LTVLNEPVFNTIALIVQAQLAAAGIEVEIDQREGGSFWSAGKDESGENMELYITSFNTSV
EEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCC
APVANTRWFLPNQIGDWNWSRWNSPEFEELYDSISVDFDIDSRSAKLIEMQRLMDESAAF
CCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCEEEEECCCCCHHHHHHHHHHCCCCEE
IWLTSDVVAYAHQTWLVPMILPNGVDCQYAYFRRA
EEEEHHHHHHHHHHEEEEEECCCCCCCEEHHEECC
>Mature Secondary Structure 
GPKLSRRHFVGGAAALSALAPLGIVPAFSQEHQSFIARVDRDVENLDPAFRTSLTDSNV
CCCCCCHHCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHCCHHHHHCCCCCHH
IRVVYQRLIDYNVGAYGWQLDAAEAIEQKSDLEITFRLKQGIMFTGGYGEMTADDVKFSL
HHHHHHHHHHCCCCCEEEEECHHHHHCCCCCCEEEEEEECCEEEECCCCCCCHHHHHHHH
ERFAFPDAEGRVSSYRQDWADLKEVVVHDKYSGSIIFERPAPNIWQSALPHASGAIVSRK
HHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHCCCCCCCHHHHH
AVEKFGAQFGRNPVGSGRYEVVSFSAQDGVVLKRNPLFLDTPGEFESFTVRFISNVKTAQ
HHHHHHHHHCCCCCCCCCEEEEEEECCCCEEEECCCEEEECCCCCHHHHHHHHHCCCEEE
LAVEAGEIDFTQVPLTTVPELERSGRVAVSVIPTQKFIWLGLNTESPKLADIKVRQAIRA
EEEECCCCEEEECCCCCCCCHHCCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHHH
AVNIDEVLLGAYQGKAPRLNTLLPAGLAGHWAEAPVYTQDLQQAQALLAEANVSGPLKVK
HCCHHHHHHHHHCCCCCCCHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEE
LTVLNEPVFNTIALIVQAQLAAAGIEVEIDQREGGSFWSAGKDESGENMELYITSFNTSV
EEEECCCHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCC
APVANTRWFLPNQIGDWNWSRWNSPEFEELYDSISVDFDIDSRSAKLIEMQRLMDESAAF
CCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCEEEEECCCCCHHHHHHHHHHCCCCEE
IWLTSDVVAYAHQTWLVPMILPNGVDCQYAYFRRA
EEEEHHHHHHHHHHEEEEEECCCCCCCEEHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]