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The map label for this gene is dmsA [H]

Identifier: 110634880

GI number: 110634880

Start: 2718826

End: 2721159

Strand: Reverse

Name: dmsA [H]

Synonym: Meso_2539

Alternate gene names: 110634880

Gene position: 2721159-2718826 (Counterclockwise)

Preceding gene: 110634881

Following gene: 110634878

Centisome position: 61.67

GC content: 62.55

Gene sequence:

>2334_bases
ATGAACAAGTCCCACCGGACTGTCCTGACATCCACGCATTGGGGAACTTACGGCATCCAGCTTGAGGGCGGGCGCATCGC
CGGCGTCGAGCCGTGGCAGGGGGACCCGGATCCTTCACCAATAGGACAATCCCTGGTGGGATCGGTCGACGGCCGGTTGC
GCGTCGCTCGACCGAGTGTGCGCCGCGAGTGGCTTGAACGCACGGGCACGCGCGCCTGCGGCAGGCGCGGCGCCGATCCG
TTCGTGGAACTGGAGTGGGACGAGGCTCTCGACCTCGTCGCCGCCGAACTGAGGCGGATTTCCCTCGCACACGGGAACTC
GGCGATCTTCGGCGGTTCCTATGGCTGGGCGAGCGCGGGCCGTTTCCACCACGCGCAAAGCCAGCTTCATCGGTTCCTGA
ACTCGATCGGCGGATATACCGCATCGGTTCATTCCTATTCCTATGCGGCCGGGCAAGTCATCCTTCCGCACATTATCGGC
AGCATGGACGGATTGACCGGGCATCACTCGACGTGGGACGGGATAGCGGCCGAAGGCCGCCTCGTGGTTTGCTTCGGCGG
GCTGCCGCACCGGAACGCGCAAGTGCAATCCGGCGGCATTGGAAAACACGCGCTTCGCAGTGCCTTGCAAGAGGCGCGCA
AGCGGAATGTTCGCTTCGTCTGCATTTCCCCTGCACGCGACGACGGGCCCGTTGACGTCGACTTTGAATGGCAGCCGCTG
CGGCCCGGCACCGATACGGCAGTGATGCTCGCCATGGCGCATGTGCTGCTGACAGAGGGCCTTGAAGACCGTGCCTTCCT
GGAGCGCTATTGCGTCGGCTTCGAAAGGATCAAGTCCTATATTCTTGGCGAGAAGGACGGCACGGCCAAAACGGCGGAGT
GGGCGGCGGAGATTTCAGGCATCGCGCCGGACTGGATTCGCGACCTCGCCCTCGCCATGGCTGCTAACCGCACGATGCTG
ATGGTCAACTGGGCAATCCAGCGAGCGGATGACGGTGAACAGCCCTATTGGATGGCGGTTACTCTAGCGGCGATGCTGGG
CCAGATTGGCCTTACCGGCGGCGGCGTCGGATTCGGCTATTCATCGACCAACGGCGCGGGGCGCGCGGAAATGCCGTTCA
AATGGCCCTCCCTCCCACAAGGGCAAAATCCGGTCGCCGACTTCATTCCCGTGGCGCGTATTACCGACATGCTGCTCAAT
CCAGGGCAGTCCTTCAATTTCGATGGCCGCCGTTTGACCTATCCGGACATCCGCATGGTGTATTGGGCCGGCGGCAATCC
GTTTCACCATCATCAGGACCTTAATCGCATGGTTGAGGCGTGGCAGCGGCCAGAGACGATCATCGTTCACGAGCCATACT
GGACCGCCGCGGCGCGTCATGCCGACATCGTGCTGCCTGTGACGACGACGCTGGAGCGGGACGACATAGCCTTTTCCAAC
CGCGACAATCTCGTCGTTGGCATGCGGAAAGTCATCGAGTCCGTTGGCAAAGCCCGCAACGATTTCGACATCCTGGCGGA
TCTGGCCGATCGCCTGGGAAAAAGGGACGTCTTCACGGGTGGAAAGACGGCCTGGGAGTGGATCGAGACGCTTTATGAGG
AAGCGCGCGAGCGTGCGGCCGCGCATGGCAGCGATATGCCAGCGTTTCCGGAGTTCTGGGAGCATGCGCATTTCGAGATC
GAGCGAACGGTGCAGTCGTCAACACTGCTTTCGAACTTCCGTAACGATCCTGATAAAAATGCGTTGCCGACGCCGTCCGG
CCGGATCGAGCTTTTCTCGGAGAGGATTGCCGGATTCGGCTATGAAGGCTATCCAGGCCATCCGGTCTGGCGCGAACCGC
GCGAGTGGCTGGGAAGTCCGCTCGCCAGTGAATTTCCGCTGCATCTCCTTTCTCCGCAGCCGGCGGACAAGCTCCACAGC
CAGTACGATCAAGGTAGCGTGAGCCGCGCTGCGAAAATCTCGGGCCGTACGCCGCTCACCATCCACAGACGAGATGCCGA
GGCCCGAGGCATCCGCGACGGCGACGTGGTCAAGGTTTTCAACCGGCGCGGAGCCTGCCTCGCAGGCGCGGTGCTCACCG
ATAATATCCTTCCCGGCGTTGTGCAGTTGCCCACTGGGGCATGGTACGATCCTGAGGACCCGCAGGTTTCTGGTTCGTTG
GAGAGGCACGGCAACCCCAATGTGCTTACGCCCGACAGGGCGACCTCGCCGCTCGGTCAGGGCCCGTCATGCAACTCCAC
GCTTGTGCAGGTGGCGCTTTTTGAAGGGGCGCCTCCGCCGGTTGGCATTTTCGAGCCGCCAGTTATCCTGCCGCGTGACG
GCGAGGTTCGGTAG

Upstream 100 bases:

>100_bases
TGCTAATCGAGCACTGTGCCTAAGCGATTGTTCAACAGCGAGCCGGTCGCCGAACAGCCTTGCACCACGTGCCGGGAAGC
GCCGGCTGGAGGTTGACAAT

Downstream 100 bases:

>100_bases
TGAATGGGCCGGCGGCATTCAACGTGCATTATCGTGCGATCCATTCCGTTGGCGAGCAGCCCATCTCCGTGCGAAAGGCA
TAGGTGAAAGCCGAGGCCGA

Product: molybdopterin oxidoreductase

Products: Biotin [C]

Alternate protein names: DMSO reductase; DMSOR [H]

Number of amino acids: Translated: 777; Mature: 777

Protein sequence:

>777_residues
MNKSHRTVLTSTHWGTYGIQLEGGRIAGVEPWQGDPDPSPIGQSLVGSVDGRLRVARPSVRREWLERTGTRACGRRGADP
FVELEWDEALDLVAAELRRISLAHGNSAIFGGSYGWASAGRFHHAQSQLHRFLNSIGGYTASVHSYSYAAGQVILPHIIG
SMDGLTGHHSTWDGIAAEGRLVVCFGGLPHRNAQVQSGGIGKHALRSALQEARKRNVRFVCISPARDDGPVDVDFEWQPL
RPGTDTAVMLAMAHVLLTEGLEDRAFLERYCVGFERIKSYILGEKDGTAKTAEWAAEISGIAPDWIRDLALAMAANRTML
MVNWAIQRADDGEQPYWMAVTLAAMLGQIGLTGGGVGFGYSSTNGAGRAEMPFKWPSLPQGQNPVADFIPVARITDMLLN
PGQSFNFDGRRLTYPDIRMVYWAGGNPFHHHQDLNRMVEAWQRPETIIVHEPYWTAAARHADIVLPVTTTLERDDIAFSN
RDNLVVGMRKVIESVGKARNDFDILADLADRLGKRDVFTGGKTAWEWIETLYEEARERAAAHGSDMPAFPEFWEHAHFEI
ERTVQSSTLLSNFRNDPDKNALPTPSGRIELFSERIAGFGYEGYPGHPVWREPREWLGSPLASEFPLHLLSPQPADKLHS
QYDQGSVSRAAKISGRTPLTIHRRDAEARGIRDGDVVKVFNRRGACLAGAVLTDNILPGVVQLPTGAWYDPEDPQVSGSL
ERHGNPNVLTPDRATSPLGQGPSCNSTLVQVALFEGAPPPVGIFEPPVILPRDGEVR

Sequences:

>Translated_777_residues
MNKSHRTVLTSTHWGTYGIQLEGGRIAGVEPWQGDPDPSPIGQSLVGSVDGRLRVARPSVRREWLERTGTRACGRRGADP
FVELEWDEALDLVAAELRRISLAHGNSAIFGGSYGWASAGRFHHAQSQLHRFLNSIGGYTASVHSYSYAAGQVILPHIIG
SMDGLTGHHSTWDGIAAEGRLVVCFGGLPHRNAQVQSGGIGKHALRSALQEARKRNVRFVCISPARDDGPVDVDFEWQPL
RPGTDTAVMLAMAHVLLTEGLEDRAFLERYCVGFERIKSYILGEKDGTAKTAEWAAEISGIAPDWIRDLALAMAANRTML
MVNWAIQRADDGEQPYWMAVTLAAMLGQIGLTGGGVGFGYSSTNGAGRAEMPFKWPSLPQGQNPVADFIPVARITDMLLN
PGQSFNFDGRRLTYPDIRMVYWAGGNPFHHHQDLNRMVEAWQRPETIIVHEPYWTAAARHADIVLPVTTTLERDDIAFSN
RDNLVVGMRKVIESVGKARNDFDILADLADRLGKRDVFTGGKTAWEWIETLYEEARERAAAHGSDMPAFPEFWEHAHFEI
ERTVQSSTLLSNFRNDPDKNALPTPSGRIELFSERIAGFGYEGYPGHPVWREPREWLGSPLASEFPLHLLSPQPADKLHS
QYDQGSVSRAAKISGRTPLTIHRRDAEARGIRDGDVVKVFNRRGACLAGAVLTDNILPGVVQLPTGAWYDPEDPQVSGSL
ERHGNPNVLTPDRATSPLGQGPSCNSTLVQVALFEGAPPPVGIFEPPVILPRDGEVR
>Mature_777_residues
MNKSHRTVLTSTHWGTYGIQLEGGRIAGVEPWQGDPDPSPIGQSLVGSVDGRLRVARPSVRREWLERTGTRACGRRGADP
FVELEWDEALDLVAAELRRISLAHGNSAIFGGSYGWASAGRFHHAQSQLHRFLNSIGGYTASVHSYSYAAGQVILPHIIG
SMDGLTGHHSTWDGIAAEGRLVVCFGGLPHRNAQVQSGGIGKHALRSALQEARKRNVRFVCISPARDDGPVDVDFEWQPL
RPGTDTAVMLAMAHVLLTEGLEDRAFLERYCVGFERIKSYILGEKDGTAKTAEWAAEISGIAPDWIRDLALAMAANRTML
MVNWAIQRADDGEQPYWMAVTLAAMLGQIGLTGGGVGFGYSSTNGAGRAEMPFKWPSLPQGQNPVADFIPVARITDMLLN
PGQSFNFDGRRLTYPDIRMVYWAGGNPFHHHQDLNRMVEAWQRPETIIVHEPYWTAAARHADIVLPVTTTLERDDIAFSN
RDNLVVGMRKVIESVGKARNDFDILADLADRLGKRDVFTGGKTAWEWIETLYEEARERAAAHGSDMPAFPEFWEHAHFEI
ERTVQSSTLLSNFRNDPDKNALPTPSGRIELFSERIAGFGYEGYPGHPVWREPREWLGSPLASEFPLHLLSPQPADKLHS
QYDQGSVSRAAKISGRTPLTIHRRDAEARGIRDGDVVKVFNRRGACLAGAVLTDNILPGVVQLPTGAWYDPEDPQVSGSL
ERHGNPNVLTPDRATSPLGQGPSCNSTLVQVALFEGAPPPVGIFEPPVILPRDGEVR

Specific function: Terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI87081994, Length=780, Percent_Identity=39.6153846153846, Blast_Score=570, Evalue=1e-163,
Organism=Escherichia coli, GI145693196, Length=782, Percent_Identity=40.0255754475703, Blast_Score=551, Evalue=1e-158,
Organism=Escherichia coli, GI1787231, Length=787, Percent_Identity=37.4841168996188, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI87081797, Length=743, Percent_Identity=31.628532974428, Blast_Score=303, Evalue=3e-83,
Organism=Escherichia coli, GI1787870, Length=722, Percent_Identity=31.994459833795, Blast_Score=284, Evalue=1e-77,
Organism=Escherichia coli, GI171474008, Length=716, Percent_Identity=31.5642458100559, Blast_Score=281, Evalue=1e-76,
Organism=Escherichia coli, GI3868721, Length=663, Percent_Identity=20.5128205128205, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006658
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006655
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.7.2.3 [C]

Molecular weight: Translated: 85447; Mature: 85447

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: PS00490 MOLYBDOPTERIN_PROK_2 ; PS00932 MOLYBDOPTERIN_PROK_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSHRTVLTSTHWGTYGIQLEGGRIAGVEPWQGDPDPSPIGQSLVGSVDGRLRVARPSV
CCCCCCEEEEECCCCEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCCEEECCHHH
RREWLERTGTRACGRRGADPFVELEWDEALDLVAAELRRISLAHGNSAIFGGSYGWASAG
HHHHHHHHCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
RFHHAQSQLHRFLNSIGGYTASVHSYSYAAGQVILPHIIGSMDGLTGHHSTWDGIAAEGR
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCE
LVVCFGGLPHRNAQVQSGGIGKHALRSALQEARKRNVRFVCISPARDDGPVDVDFEWQPL
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEECC
RPGTDTAVMLAMAHVLLTEGLEDRAFLERYCVGFERIKSYILGEKDGTAKTAEWAAEISG
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
IAPDWIRDLALAMAANRTMLMVNWAIQRADDGEQPYWMAVTLAAMLGQIGLTGGGVGFGY
CCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SSTNGAGRAEMPFKWPSLPQGQNPVADFIPVARITDMLLNPGQSFNFDGRRLTYPDIRMV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEE
YWAGGNPFHHHQDLNRMVEAWQRPETIIVHEPYWTAAARHADIVLPVTTTLERDDIAFSN
EEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCEEEEEEECCCCCCCCCCCC
RDNLVVGMRKVIESVGKARNDFDILADLADRLGKRDVFTGGKTAWEWIETLYEEARERAA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHGSDMPAFPEFWEHAHFEIERTVQSSTLLSNFRNDPDKNALPTPSGRIELFSERIAGFG
HCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
YEGYPGHPVWREPREWLGSPLASEFPLHLLSPQPADKLHSQYDQGSVSRAAKISGRTPLT
CCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCHHHHHHHCCCCCHHHHHHCCCCCCEE
IHRRDAEARGIRDGDVVKVFNRRGACLAGAVLTDNILPGVVQLPTGAWYDPEDPQVSGSL
EEECCCHHCCCCCCCEEEEECCCCCEEECHHHHCCCCCCEEECCCCCCCCCCCCCCCCCH
ERHGNPNVLTPDRATSPLGQGPSCNSTLVQVALFEGAPPPVGIFEPPVILPRDGEVR
HHCCCCCEECCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCCCEECCCCCCCC
>Mature Secondary Structure
MNKSHRTVLTSTHWGTYGIQLEGGRIAGVEPWQGDPDPSPIGQSLVGSVDGRLRVARPSV
CCCCCCEEEEECCCCEEEEEECCCEEECCCCCCCCCCCCHHHHHHHHCCCCCEEECCHHH
RREWLERTGTRACGRRGADPFVELEWDEALDLVAAELRRISLAHGNSAIFGGSYGWASAG
HHHHHHHHCCHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCC
RFHHAQSQLHRFLNSIGGYTASVHSYSYAAGQVILPHIIGSMDGLTGHHSTWDGIAAEGR
HHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCE
LVVCFGGLPHRNAQVQSGGIGKHALRSALQEARKRNVRFVCISPARDDGPVDVDFEWQPL
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEEEECC
RPGTDTAVMLAMAHVLLTEGLEDRAFLERYCVGFERIKSYILGEKDGTAKTAEWAAEISG
CCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCC
IAPDWIRDLALAMAANRTMLMVNWAIQRADDGEQPYWMAVTLAAMLGQIGLTGGGVGFGY
CCHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
SSTNGAGRAEMPFKWPSLPQGQNPVADFIPVARITDMLLNPGQSFNFDGRRLTYPDIRMV
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCEEEE
YWAGGNPFHHHQDLNRMVEAWQRPETIIVHEPYWTAAARHADIVLPVTTTLERDDIAFSN
EEECCCCCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHCCCEEEEEEECCCCCCCCCCCC
RDNLVVGMRKVIESVGKARNDFDILADLADRLGKRDVFTGGKTAWEWIETLYEEARERAA
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AHGSDMPAFPEFWEHAHFEIERTVQSSTLLSNFRNDPDKNALPTPSGRIELFSERIAGFG
HCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCC
YEGYPGHPVWREPREWLGSPLASEFPLHLLSPQPADKLHSQYDQGSVSRAAKISGRTPLT
CCCCCCCCCCCCHHHHCCCCCCCCCCEEECCCCCHHHHHHHCCCCCHHHHHHCCCCCCEE
IHRRDAEARGIRDGDVVKVFNRRGACLAGAVLTDNILPGVVQLPTGAWYDPEDPQVSGSL
EEECCCHHCCCCCCCEEEEECCCCCEEECHHHHCCCCCCEEECCCCCCCCCCCCCCCCCH
ERHGNPNVLTPDRATSPLGQGPSCNSTLVQVALFEGAPPPVGIFEPPVILPRDGEVR
HHCCCCCEECCCCCCCCCCCCCCCCHHEEEEEEECCCCCCCCCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds) [C]

Specific reaction: Reduces A Spontaneous Oxidation Product Of Biotin, D-Biotin D-Sulfoxide (Bso Or Bds), Back To Biotin. [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8645727; 8534974; 7625833; 8658134 [H]