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The map label for this gene is hpcG [H]

Identifier: 110634845

GI number: 110634845

Start: 2682848

End: 2683648

Strand: Reverse

Name: hpcG [H]

Synonym: Meso_2504

Alternate gene names: 110634845

Gene position: 2683648-2682848 (Counterclockwise)

Preceding gene: 110634846

Following gene: 110634844

Centisome position: 60.82

GC content: 60.55

Gene sequence:

>801_bases
ATGCTGAGCAGGGCTGAGATCGAACTGGCTGCGGCCGATCTGTTGCGTGCCGAAGAGACGTGCGCTCAGATCGGGCTTCT
GTCCATCCGGCACCCCGAGATCACGCTCGACGATGCCTATGCGATTCAGTCGGCCCAGATGGCGCAAAAGCTCGCCAGAG
GCCGCAAGATCATCGGCTGGAAAATCGGGCTGACTTCGAAGGTCATGCAGGATGCGCTCGGTATCGACACGCCGGACAGC
GGCGTGATCTATGACGATATGGATTTTGCCAGCGGCTCGACGGTCCCCGCAGGCCGGTTCATACAGCCGCGGATCGAGAC
GGAGATCGCCTTCGTCATGAAGTCACCGCTCGACGGCAAGGTGTCACGGGAGGACGTGCTCGCCGCCACGGATTACGTTG
CACCTGCCATCGAGATCCTCGATACGCGAATCCAGCGAAAGGATCACGAGACAGGCCAGACGCGCAGGATCTTCGACACC
GTAGCGGACAATGCCGCCAATGGTGGAATCGTTCTGGGATGCGAACGGCACGGGCCCGAGGACTTCGATCTGCGCTGGGT
TGGCGCTATCGTATCCAAGAACGAGCAGGTGGAGGCAACCGGCCTCGGAGCGGCGATTCTCAACGATCCGGTGCAGGGCA
TTGTTTGGCTCGCGCGCCGTATGAATCAGTATAATCAGCGGATCGAGGCCGGGCAGGTCGTCCTTGCCGGCTCGTTCATC
GCACCGATCGAGTGCCCGCCAGGAACGAAGATCCATGCCGATTTCGGCAGTTTCGGATCTGCTTCGATTACCTTTGCCTG
A

Upstream 100 bases:

>100_bases
GCGCGAGGTTCGATCCGCCGGTTTGGCTCAAGCCCGGCGATGTGGTGGAGGTCGAAGCCGAAGGCATAGGCATCCTGCGC
AACGGCATTGAGGACGAGTG

Downstream 100 bases:

>100_bases
AAGGATTGCATCATGCCAGCACCGAGGAACAGCTTCAAGGCGCGGTTGAAGAAGGGAGAGACCCAGATCGGTCTTTGGCT
GGGACTTGCCGAAGCAACCA

Product: 2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Products: NA

Alternate protein names: OHED hydratase [H]

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MLSRAEIELAAADLLRAEETCAQIGLLSIRHPEITLDDAYAIQSAQMAQKLARGRKIIGWKIGLTSKVMQDALGIDTPDS
GVIYDDMDFASGSTVPAGRFIQPRIETEIAFVMKSPLDGKVSREDVLAATDYVAPAIEILDTRIQRKDHETGQTRRIFDT
VADNAANGGIVLGCERHGPEDFDLRWVGAIVSKNEQVEATGLGAAILNDPVQGIVWLARRMNQYNQRIEAGQVVLAGSFI
APIECPPGTKIHADFGSFGSASITFA

Sequences:

>Translated_266_residues
MLSRAEIELAAADLLRAEETCAQIGLLSIRHPEITLDDAYAIQSAQMAQKLARGRKIIGWKIGLTSKVMQDALGIDTPDS
GVIYDDMDFASGSTVPAGRFIQPRIETEIAFVMKSPLDGKVSREDVLAATDYVAPAIEILDTRIQRKDHETGQTRRIFDT
VADNAANGGIVLGCERHGPEDFDLRWVGAIVSKNEQVEATGLGAAILNDPVQGIVWLARRMNQYNQRIEAGQVVLAGSFI
APIECPPGTKIHADFGSFGSASITFA
>Mature_266_residues
MLSRAEIELAAADLLRAEETCAQIGLLSIRHPEITLDDAYAIQSAQMAQKLARGRKIIGWKIGLTSKVMQDALGIDTPDS
GVIYDDMDFASGSTVPAGRFIQPRIETEIAFVMKSPLDGKVSREDVLAATDYVAPAIEILDTRIQRKDHETGQTRRIFDT
VADNAANGGIVLGCERHGPEDFDLRWVGAIVSKNEQVEATGLGAAILNDPVQGIVWLARRMNQYNQRIEAGQVVLAGSFI
APIECPPGTKIHADFGSFGSASITFA

Specific function: Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4- dihydoxy-hept-2-ene-1,7-dioic acid (HHED) [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=270, Percent_Identity=31.8518518518519, Blast_Score=144, Evalue=6e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234
- InterPro:   IPR012690 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: 4.2.1.-

Molecular weight: Translated: 28765; Mature: 28765

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSRAEIELAAADLLRAEETCAQIGLLSIRHPEITLDDAYAIQSAQMAQKLARGRKIIGW
CCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEECHHHHHHHHHHHHHHHCCCEEEEE
KIGLTSKVMQDALGIDTPDSGVIYDDMDFASGSTVPAGRFIQPRIETEIAFVMKSPLDGK
EECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCC
VSREDVLAATDYVAPAIEILDTRIQRKDHETGQTRRIFDTVADNAANGGIVLGCERHGPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCC
DFDLRWVGAIVSKNEQVEATGLGAAILNDPVQGIVWLARRMNQYNQRIEAGQVVLAGSFI
CCCEEEEEHHHCCCCEEEHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEE
APIECPPGTKIHADFGSFGSASITFA
EECCCCCCCEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MLSRAEIELAAADLLRAEETCAQIGLLSIRHPEITLDDAYAIQSAQMAQKLARGRKIIGW
CCCCHHHHHHHHHHHHHHHHHHHHCCEEECCCCEEECHHHHHHHHHHHHHHHCCCEEEEE
KIGLTSKVMQDALGIDTPDSGVIYDDMDFASGSTVPAGRFIQPRIETEIAFVMKSPLDGK
EECCHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCCHHHHHEEEEECCCCCCC
VSREDVLAATDYVAPAIEILDTRIQRKDHETGQTRRIFDTVADNAANGGIVLGCERHGPE
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCEEEEECCCCCC
DFDLRWVGAIVSKNEQVEATGLGAAILNDPVQGIVWLARRMNQYNQRIEAGQVVLAGSFI
CCCEEEEEHHHCCCCEEEHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCEE
APIECPPGTKIHADFGSFGSASITFA
EECCCCCCCEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7737515 [H]