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The map label for this gene is siaP [H]

Identifier: 110634830

GI number: 110634830

Start: 2667153

End: 2668199

Strand: Direct

Name: siaP [H]

Synonym: Meso_2489

Alternate gene names: 110634830

Gene position: 2667153-2668199 (Clockwise)

Preceding gene: 110634828

Following gene: 110634831

Centisome position: 60.45

GC content: 61.22

Gene sequence:

>1047_bases
ATGATCAGGCGCAGAGATTTTCTGGTAGGTTCGGCGTCCGCGCTGGCGCTGCCGGCTTATATTCGCTCCAGCTTCGCGCA
GAGCGCAGAGTACACGCTGAAGCTGCATCACTTTTTGGGCCCCCAAGCACCAGCTCAGACGCAGATGCTGGAGCCTTGGG
CCAAGCGGATCGAGGATGATTCCGGCGGCCGAGTGAAGATAGAGCTCTACCCCGCTATGTCGCTTGGGGGCGCGCCGAAC
CAGCTTTTCCGGCAGGCGGCGGAAGGCGTCGTCGACATTATCTGGGCTGTCAACGGCTACACGCCGGGCCTTTTCCCGCG
CTCGGAGGTGTTCGAGCTTCCGACAATTTTCACCAATGACATCGTGGCGGCGAATCTCGCCATGCGCGATCTGTTCGAAA
GCCATCTCGCTCCTGAATTCGCCGATGTGCACGTGCTTTTCATGCATGTCCATGCCGGTCAGGCGCTTCATATGGCCAGT
GAACTCGTTCGCACGCCCGACGATACCAAAGGCAAGAAGCTGCGTGTGCCCGGCCCGACCGGTAATGCGGTGGTCGAGGC
CATGGGCGCAACACCCGTCACCATGCCGGTGCCGGACCTGCCTCAGGCGCTAACCACAAACGCCGTCGATGGAGCGCTGA
TACCCTGGGAGATCATTCCTGCGCTGCAGCTTTGGGAAACCACGAAATACCAGATCGAAGGACCTGATAACAACCGCTTC
GGCACGACCACCTTCCAGGTCTCGATGAACCAGGGGCGGTGGGAAGAACTGCCTGATGATCTCAAGGAGGTCTTCAACAA
GCACTCCGGCGAGGACTGGTTGCGCGAAGTCGGCCAGATCTGGCGCGGTATCGACGACCGTGGCATTCAACTCGCGGTGG
AGCAAGGTAACGAGCATGTGGTGCTCACCGAGGAGGAAATGGGTGCCTTCAATACCGCGCTCGCGCCGGTCGTCGACCGG
TGGGTCGCGGAACATTCAAATGCGGGCTTCGACCCCGCCGAGCTGGTCGAGGCCGCCAGGCAGGCGCTGGCGGCGCACCA
GTCTTGA

Upstream 100 bases:

>100_bases
CCCTTGAACCACTGCCTTAGCTTGTGTCGGATTATATGCGTGGAGGAAAGTCGCATATAGAATGACGGGTGATCATCAGG
ATCGCAGACGGGAGGAAAAT

Downstream 100 bases:

>100_bases
GCAAGATACCCGGCAGACAGGCGGAGACGGGCGATAAGCCGCCCGTTACGCCGGTCCTCGCGCAGATCGCCGCCCTGATT
GCCAGCCTCTCCCGCTGGTG

Product: TRAP dicarboxylate transporter- DctP subunit

Products: NA

Alternate protein names: Extracytoplasmic solute receptor protein siaP; N-acetylneuraminic-binding protein; Neu5Ac-binding protein [H]

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MIRRRDFLVGSASALALPAYIRSSFAQSAEYTLKLHHFLGPQAPAQTQMLEPWAKRIEDDSGGRVKIELYPAMSLGGAPN
QLFRQAAEGVVDIIWAVNGYTPGLFPRSEVFELPTIFTNDIVAANLAMRDLFESHLAPEFADVHVLFMHVHAGQALHMAS
ELVRTPDDTKGKKLRVPGPTGNAVVEAMGATPVTMPVPDLPQALTTNAVDGALIPWEIIPALQLWETTKYQIEGPDNNRF
GTTTFQVSMNQGRWEELPDDLKEVFNKHSGEDWLREVGQIWRGIDDRGIQLAVEQGNEHVVLTEEEMGAFNTALAPVVDR
WVAEHSNAGFDPAELVEAARQALAAHQS

Sequences:

>Translated_348_residues
MIRRRDFLVGSASALALPAYIRSSFAQSAEYTLKLHHFLGPQAPAQTQMLEPWAKRIEDDSGGRVKIELYPAMSLGGAPN
QLFRQAAEGVVDIIWAVNGYTPGLFPRSEVFELPTIFTNDIVAANLAMRDLFESHLAPEFADVHVLFMHVHAGQALHMAS
ELVRTPDDTKGKKLRVPGPTGNAVVEAMGATPVTMPVPDLPQALTTNAVDGALIPWEIIPALQLWETTKYQIEGPDNNRF
GTTTFQVSMNQGRWEELPDDLKEVFNKHSGEDWLREVGQIWRGIDDRGIQLAVEQGNEHVVLTEEEMGAFNTALAPVVDR
WVAEHSNAGFDPAELVEAARQALAAHQS
>Mature_348_residues
MIRRRDFLVGSASALALPAYIRSSFAQSAEYTLKLHHFLGPQAPAQTQMLEPWAKRIEDDSGGRVKIELYPAMSLGGAPN
QLFRQAAEGVVDIIWAVNGYTPGLFPRSEVFELPTIFTNDIVAANLAMRDLFESHLAPEFADVHVLFMHVHAGQALHMAS
ELVRTPDDTKGKKLRVPGPTGNAVVEAMGATPVTMPVPDLPQALTTNAVDGALIPWEIIPALQLWETTKYQIEGPDNNRF
GTTTFQVSMNQGRWEELPDDLKEVFNKHSGEDWLREVGQIWRGIDDRGIQLAVEQGNEHVVLTEEEMGAFNTALAPVVDR
WVAEHSNAGFDPAELVEAARQALAAHQS

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid. This protein specifically binds sialic acid [H]

COG id: COG1638

COG function: function code G; TRAP-type C4-dicarboxylate transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 7 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018389
- InterPro:   IPR004682 [H]

Pfam domain/function: PF03480 SBP_bac_7 [H]

EC number: NA

Molecular weight: Translated: 38361; Mature: 38361

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRRRDFLVGSASALALPAYIRSSFAQSAEYTLKLHHFLGPQAPAQTQMLEPWAKRIEDD
CCCCCCEEECCCHHHHHHHHHHHHHHCCHHHEEEEHHHCCCCCCCHHHHHHHHHHHCCCC
SGGRVKIELYPAMSLGGAPNQLFRQAAEGVVDIIWAVNGYTPGLFPRSEVFELPTIFTND
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEHHEECCCCCCCCCCHHHHHCCCHHHCH
IVAANLAMRDLFESHLAPEFADVHVLFMHVHAGQALHMASELVRTPDDTKGKKLRVPGPT
HHHHHHHHHHHHHHHCCCCHHCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCCCC
GNAVVEAMGATPVTMPVPDLPQALTTNAVDGALIPWEIIPALQLWETTKYQIEGPDNNRF
CCHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
GTTTFQVSMNQGRWEELPDDLKEVFNKHSGEDWLREVGQIWRGIDDRGIQLAVEQGNEHV
CCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
VLTEEEMGAFNTALAPVVDRWVAEHSNAGFDPAELVEAARQALAAHQS
EEEHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRRRDFLVGSASALALPAYIRSSFAQSAEYTLKLHHFLGPQAPAQTQMLEPWAKRIEDD
CCCCCCEEECCCHHHHHHHHHHHHHHCCHHHEEEEHHHCCCCCCCHHHHHHHHHHHCCCC
SGGRVKIELYPAMSLGGAPNQLFRQAAEGVVDIIWAVNGYTPGLFPRSEVFELPTIFTND
CCCEEEEEEEECCCCCCCHHHHHHHHHHHHEEEHHEECCCCCCCCCCHHHHHCCCHHHCH
IVAANLAMRDLFESHLAPEFADVHVLFMHVHAGQALHMASELVRTPDDTKGKKLRVPGPT
HHHHHHHHHHHHHHHCCCCHHCEEEEEEEECCCHHHHHHHHHHCCCCCCCCCEEECCCCC
GNAVVEAMGATPVTMPVPDLPQALTTNAVDGALIPWEIIPALQLWETTKYQIEGPDNNRF
CCHHHHCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCCC
GTTTFQVSMNQGRWEELPDDLKEVFNKHSGEDWLREVGQIWRGIDDRGIQLAVEQGNEHV
CCEEEEEECCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCEE
VLTEEEMGAFNTALAPVVDRWVAEHSNAGFDPAELVEAARQALAAHQS
EEEHHHHCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA