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The map label for this gene is coxM [H]

Identifier: 110634815

GI number: 110634815

Start: 2652626

End: 2653447

Strand: Direct

Name: coxM [H]

Synonym: Meso_2474

Alternate gene names: 110634815

Gene position: 2652626-2653447 (Clockwise)

Preceding gene: 110634814

Following gene: 110634816

Centisome position: 60.12

GC content: 57.79

Gene sequence:

>822_bases
ATGGTCCCGGCATTTATACTCGTCCTCGTTGTCCTGGGCTCGATATTGTTTCACATTTTGAGCCCATGGTGGTGGCCGCC
CATAGCTTCGAACTGGAGCTATATAGACCATACGCTCGTCATCACATTCTGGATCACGGGAGCCGTATTTTCCGCGGTCG
TCCTGTTCATGGCGTATTGCGTCTACCGGTTCCGGCACCGCCCGGGCTCCAAGGCCGCCTATGAACCGGAAAGCAAGAAG
CTGGAATGGTGGCTCACCATCGGCACGGCAGTAGGGGTGGCGGCCATGCTTGCGCCCGGCCTCTATGTCTGGGCGCAGTT
TGTCACCGTCCCCGATGACGCGACCGAGATAGAGGTGGTCGCGCAGCAGTGGCAGTGGAACTACAGGTTGCCGGGCGAAG
ACGGAAGGCTCGGCAAATCCGATAGTCAGCTCATCTCATTCGAAAACCCGTTAGGCATCAACCCTGATGATCCCAATGGC
CAAGACGATATCGTGATCGAAGCAAGCGATCTGCATCTGCCGGTCGATAAGCCCGTGAAGGTGCTGCTGCGCTCGATCGA
TGTTCTCCACGATTTCTATGTACCCGAGTTCCGCGCCAAGATGGACATGGTGCCTGGCATGGTCACCTATTTCTGGTTCA
CGCCCACGAAGACCGGAACCTATGAAGTCTTGTGCGCGGAGCTGTGCGGCGTGGGCCATAGCTATATGCGCGGCGCGGTT
CTGGTCGACACCGAGGAGGATTACCAGGCCTGGCTGCAGGAACAATCAACCTTTGCAGAGCTAACCGACCTCCGGAACGT
GGCTGAGGAGGTCAAGCCGTGA

Upstream 100 bases:

>100_bases
CCGTCTTCCCCTAGACTGGAAATCTCAAATCATTTCAGGTTATGATGAACGCGGTCCCCTAGTGGATAGGAGGTCCCAGG
GGACCGGGAGGAACGGGAAG

Downstream 100 bases:

>100_bases
TCAGGGAGACCCAAGCATAGCGCAAGCAATTCCATTGCAGGCGGGATCAGCCTGCAATGGAGCCAGGGAGGATGAGCGAT
GGTCGACGCCACGCCCCGAA

Product: cytochrome c oxidase, subunit II

Products: NA

Alternate protein names: Alternative cytochrome c oxidase polypeptide II; Cytochrome BB3 subunit 2; Oxidase BB(3) subunit 2 [H]

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MVPAFILVLVVLGSILFHILSPWWWPPIASNWSYIDHTLVITFWITGAVFSAVVLFMAYCVYRFRHRPGSKAAYEPESKK
LEWWLTIGTAVGVAAMLAPGLYVWAQFVTVPDDATEIEVVAQQWQWNYRLPGEDGRLGKSDSQLISFENPLGINPDDPNG
QDDIVIEASDLHLPVDKPVKVLLRSIDVLHDFYVPEFRAKMDMVPGMVTYFWFTPTKTGTYEVLCAELCGVGHSYMRGAV
LVDTEEDYQAWLQEQSTFAELTDLRNVAEEVKP

Sequences:

>Translated_273_residues
MVPAFILVLVVLGSILFHILSPWWWPPIASNWSYIDHTLVITFWITGAVFSAVVLFMAYCVYRFRHRPGSKAAYEPESKK
LEWWLTIGTAVGVAAMLAPGLYVWAQFVTVPDDATEIEVVAQQWQWNYRLPGEDGRLGKSDSQLISFENPLGINPDDPNG
QDDIVIEASDLHLPVDKPVKVLLRSIDVLHDFYVPEFRAKMDMVPGMVTYFWFTPTKTGTYEVLCAELCGVGHSYMRGAV
LVDTEEDYQAWLQEQSTFAELTDLRNVAEEVKP
>Mature_273_residues
MVPAFILVLVVLGSILFHILSPWWWPPIASNWSYIDHTLVITFWITGAVFSAVVLFMAYCVYRFRHRPGSKAAYEPESKK
LEWWLTIGTAVGVAAMLAPGLYVWAQFVTVPDDATEIEVVAQQWQWNYRLPGEDGRLGKSDSQLISFENPLGINPDDPNG
QDDIVIEASDLHLPVDKPVKVLLRSIDVLHDFYVPEFRAKMDMVPGMVTYFWFTPTKTGTYEVLCAELCGVGHSYMRGAV
LVDTEEDYQAWLQEQSTFAELTDLRNVAEEVKP

Specific function: Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A ce

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=160, Percent_Identity=28.75, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6226540, Length=209, Percent_Identity=24.4019138755981, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 30950; Mature: 30950

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS00078 COX2 ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVPAFILVLVVLGSILFHILSPWWWPPIASNWSYIDHTLVITFWITGAVFSAVVLFMAYC
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYRFRHRPGSKAAYEPESKKLEWWLTIGTAVGVAAMLAPGLYVWAQFVTVPDDATEIEVV
HHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCHHHHHHHHEECCCCCHHHHHH
AQQWQWNYRLPGEDGRLGKSDSQLISFENPLGINPDDPNGQDDIVIEASDLHLPVDKPVK
HHHCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHH
VLLRSIDVLHDFYVPEFRAKMDMVPGMVTYFWFTPTKTGTYEVLCAELCGVGHSYMRGAV
HHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCE
LVDTEEDYQAWLQEQSTFAELTDLRNVAEEVKP
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVPAFILVLVVLGSILFHILSPWWWPPIASNWSYIDHTLVITFWITGAVFSAVVLFMAYC
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
VYRFRHRPGSKAAYEPESKKLEWWLTIGTAVGVAAMLAPGLYVWAQFVTVPDDATEIEVV
HHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHCHHHHHHHHEECCCCCHHHHHH
AQQWQWNYRLPGEDGRLGKSDSQLISFENPLGINPDDPNGQDDIVIEASDLHLPVDKPVK
HHHCCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHH
VLLRSIDVLHDFYVPEFRAKMDMVPGMVTYFWFTPTKTGTYEVLCAELCGVGHSYMRGAV
HHHHHHHHHHHHCCCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHCCCHHHHCCCE
LVDTEEDYQAWLQEQSTFAELTDLRNVAEEVKP
EEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1444719; 12597275 [H]