Click here to switch to the map view.

The map label for this gene is moeA [H]

Identifier: 110634775

GI number: 110634775

Start: 2610889

End: 2612016

Strand: Reverse

Name: moeA [H]

Synonym: Meso_2434

Alternate gene names: 110634775

Gene position: 2612016-2610889 (Counterclockwise)

Preceding gene: 110634776

Following gene: 110634774

Centisome position: 59.2

GC content: 66.58

Gene sequence:

>1128_bases
ATGATGACGACGCCTCCTCCAGCCGGCATTCTGACCAATCTCAAAGCGGCGCTCGCCGCACTGCTTGATGGCGTGAGGCC
GGTTGCCCCTTGTTTTGTGCCGCTCGAACAGGCGCTGGGCCGCGTTGCCGCCGAGATGCCGGGCATAGCGGCGCAGCCCC
AGCGGAATATCGCTGCCATCGACGGCTGGGCGTGCCGGGCGCTGGATCTTGTGGGAGCGTCTTCCTATTCGCCACTGGCG
CTGCCTACGGTTCCGATCTGGGTGGAAACGGGCGAAGTCATGCCGGAGGATTGTGACTGCGTACTCGAAGCAGATCTGGT
CGATTGCAGCGGCCCGATGGCCCAGGCCGTCGGCGAGGCCGCGCCCGGCCAAGGCATGCGTCGGGCGGGCGAGGATTTGG
CGGCCGGCCGCCCGCCGGCCGTTGCAGGAAATATGATCTGCAGCATCGACCTGCTGGTCGCGCGGAGGCTAGGGTTGGAC
AAGCTTGCCGTGCGGACTCCGCGTGCTCACATGATAAATGTCGCCGCCGTGAGCCAGGAGACCTTCTCGGGGCAGTTCGT
CGCCGAGTATCTGATGGAGGCGGGCGCGACCGTTACCGCGATGGAAACCACGGCGCGAGACGCAGCCTCGATTGCCGCCG
CGCTTGATGGAGAGAGCTGCGACCTGCTCCTCCTGATCGGAGGCACGGGCGACGGTCGCTCCGATATGACCGCCGAGGCG
CTTGCGCGGCGCGGGGTGCTGATTGCGCACCGGCTCGCCTTGCGGCCCGGCGGGACCACGGCAATCGGCCGGCTCGGAAA
AGTTCCGGTGATTGCGTTGCCCGGCTCGCCCGACCAGGCCTTTGCCGCCTTTCTCGCACTCGTCCAGCCAGTCCTCGATC
ACTTGTCCGGCCGTTCCGAACGGAGCGGCATCACCTTGCCGTTGTCGCGGAAGGTCCCGTCAGCCATCGGATTAAGCGAG
ATCGCCCTGCTTGGCCTGGAGCAAGGAGCGTGGGCGCCGCTCGCTGTCGGTAATTTCTCGCTGGACGCCATGCGGCTGGC
TGACGCCTGGCTTGCGGTGCCGGATGACAGCGAGGGATATGCCGCCGGCACGCCTGTCGCAGCTTTTCCGCTCCGCAGCA
TGAATTGA

Upstream 100 bases:

>100_bases
AATATAAGATTGGTGGCCAGCAGCTGTTCTTCCCGAACGCGGAGCAGGATCGTTCCTGAGGACAGTTGCAAACCCCTTGG
CGACTGTCCATCATCGGGAG

Downstream 100 bases:

>100_bases
GCCCGGACATGTCTCAGTCTCCCAACTCCATCCGGCACGATTCCCATCAGGAGCAGTTCCTAACGATCTTGTCGCGCGAG
GAGGCGCTGGCCCGCTTTGA

Product: molybdopterin binding domain-containing protein

Products: NA

Alternate protein names: MPT Mo-transferase [H]

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MMTTPPPAGILTNLKAALAALLDGVRPVAPCFVPLEQALGRVAAEMPGIAAQPQRNIAAIDGWACRALDLVGASSYSPLA
LPTVPIWVETGEVMPEDCDCVLEADLVDCSGPMAQAVGEAAPGQGMRRAGEDLAAGRPPAVAGNMICSIDLLVARRLGLD
KLAVRTPRAHMINVAAVSQETFSGQFVAEYLMEAGATVTAMETTARDAASIAAALDGESCDLLLLIGGTGDGRSDMTAEA
LARRGVLIAHRLALRPGGTTAIGRLGKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSERSGITLPLSRKVPSAIGLSE
IALLGLEQGAWAPLAVGNFSLDAMRLADAWLAVPDDSEGYAAGTPVAAFPLRSMN

Sequences:

>Translated_375_residues
MMTTPPPAGILTNLKAALAALLDGVRPVAPCFVPLEQALGRVAAEMPGIAAQPQRNIAAIDGWACRALDLVGASSYSPLA
LPTVPIWVETGEVMPEDCDCVLEADLVDCSGPMAQAVGEAAPGQGMRRAGEDLAAGRPPAVAGNMICSIDLLVARRLGLD
KLAVRTPRAHMINVAAVSQETFSGQFVAEYLMEAGATVTAMETTARDAASIAAALDGESCDLLLLIGGTGDGRSDMTAEA
LARRGVLIAHRLALRPGGTTAIGRLGKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSERSGITLPLSRKVPSAIGLSE
IALLGLEQGAWAPLAVGNFSLDAMRLADAWLAVPDDSEGYAAGTPVAAFPLRSMN
>Mature_375_residues
MMTTPPPAGILTNLKAALAALLDGVRPVAPCFVPLEQALGRVAAEMPGIAAQPQRNIAAIDGWACRALDLVGASSYSPLA
LPTVPIWVETGEVMPEDCDCVLEADLVDCSGPMAQAVGEAAPGQGMRRAGEDLAAGRPPAVAGNMICSIDLLVARRLGLD
KLAVRTPRAHMINVAAVSQETFSGQFVAEYLMEAGATVTAMETTARDAASIAAALDGESCDLLLLIGGTGDGRSDMTAEA
LARRGVLIAHRLALRPGGTTAIGRLGKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSERSGITLPLSRKVPSAIGLSE
IALLGLEQGAWAPLAVGNFSLDAMRLADAWLAVPDDSEGYAAGTPVAAFPLRSMN

Specific function: Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP [H]

COG id: COG0303

COG function: function code H; Molybdopterin biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moeA family [H]

Homologues:

Organism=Escherichia coli, GI1787049, Length=340, Percent_Identity=27.9411764705882, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR008284
- InterPro:   IPR005111
- InterPro:   IPR005110
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth; PF03454 MoeA_C; PF03453 MoeA_N [H]

EC number: NA

Molecular weight: Translated: 38551; Mature: 38551

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS01078 MOCF_BIOSYNTHESIS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTPPPAGILTNLKAALAALLDGVRPVAPCFVPLEQALGRVAAEMPGIAAQPQRNIAAI
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
DGWACRALDLVGASSYSPLALPTVPIWVETGEVMPEDCDCVLEADLVDCSGPMAQAVGEA
CCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHCCC
APGQGMRRAGEDLAAGRPPAVAGNMICSIDLLVARRLGLDKLAVRTPRAHMINVAAVSQE
CCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHEEEEEEECCH
TFSGQFVAEYLMEAGATVTAMETTARDAASIAAALDGESCDLLLLIGGTGDGRSDMTAEA
HCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHH
LARRGVLIAHRLALRPGGTTAIGRLGKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSE
HHHCCHHEEHHEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
RSGITLPLSRKVPSAIGLSEIALLGLEQGAWAPLAVGNFSLDAMRLADAWLAVPDDSEGY
CCCEEEEECCCCCCCCCHHHHHHEECCCCCCCCEEECCCCHHHHHHHHHHEECCCCCCCC
AAGTPVAAFPLRSMN
CCCCCHHCCCCCCCC
>Mature Secondary Structure
MMTTPPPAGILTNLKAALAALLDGVRPVAPCFVPLEQALGRVAAEMPGIAAQPQRNIAAI
CCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
DGWACRALDLVGASSYSPLALPTVPIWVETGEVMPEDCDCVLEADLVDCSGPMAQAVGEA
CCHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCCCHHHHHHCCC
APGQGMRRAGEDLAAGRPPAVAGNMICSIDLLVARRLGLDKLAVRTPRAHMINVAAVSQE
CCCCHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCHHEEEEEEECCH
TFSGQFVAEYLMEAGATVTAMETTARDAASIAAALDGESCDLLLLIGGTGDGRSDMTAEA
HCCHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCHHHHHH
LARRGVLIAHRLALRPGGTTAIGRLGKVPVIALPGSPDQAFAAFLALVQPVLDHLSGRSE
HHHCCHHEEHHEEECCCCCHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
RSGITLPLSRKVPSAIGLSEIALLGLEQGAWAPLAVGNFSLDAMRLADAWLAVPDDSEGY
CCCEEEEECCCCCCCCCHHHHHHEECCCCCCCCEEECCCCHHHHHHHHHHEECCCCCCCC
AAGTPVAAFPLRSMN
CCCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3045084; 8905232; 9278503; 9515915 [H]