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The map label for this gene is gsiC [H]

Identifier: 110634724

GI number: 110634724

Start: 2537435

End: 2538379

Strand: Direct

Name: gsiC [H]

Synonym: Meso_2382

Alternate gene names: 110634724

Gene position: 2537435-2538379 (Clockwise)

Preceding gene: 110634723

Following gene: 110634725

Centisome position: 57.51

GC content: 59.15

Gene sequence:

>945_bases
ATGAACTACTATCTCCGCAGACTGGCTGTCGCGATCGCCACAGTGCTGATCTCGTCCAGCCTGGTCTTCTTCGCCATTCG
CATTCTCCCAGGCGATCCGGTCATGATGCTGCTCGGGGAAAGCGCTGCAACACCGGAGGTCATCGCGCGTATGGCGGAGC
GGCTGGGCATGGACGCGCCGCTCCATGTGCAATACTTCCGCTGGCTTACCGATCTGCTGCAGCTCGACTTCGGGACGTCG
ATCGGGACAGGCCTGCCGGTGGCGAATGAGTTGATCAAACGTTTGCCGCGCTCGTTGGAACTAATGGCGGGCGGCATTCT
TGTCAGCCTGTCAATCGGCATCCCGCTGGGTGTGGTCGCCGCGCGGCGGCCGGACAGCTTCATCGGCAATGCGGCCTCGG
TTCTGGCGCTGATCGGCCTGTCGGCTCCAACCTTCGTCAAAGGCCTGATCCTGATCATCATCTTCAGCATCACACTCGGC
CTTCTGCCGTCATCCGGCTTTACGCCCTTCACTCAGGATCCGGCCGCCAATCTGAGAAACCTTATTCTGCCCTCGCTCAC
GCTGGGATTGGGTTTTGCTGGCGTCGTGCAGCGGATAACGCGGGCGAGCTTGGCCGAAACGCTAGGTAAAGACTACGTCC
GTACGGTCCGAGCCAAGGGCGTTTCCGAAAACGCCTCCGTATATCGACATGCCCTACCGAATGCCATGATTCCCGTTATT
GCCGTCGTGGGTATCCGTATCGGCTCAATGCTGGGCGGCATGGTCGTGATCGAGAACCTATTCAACTGGCCTGGCCTCAG
CTCCTATTTGATCGAGGCCTGCTATGCCCGCGATTATCCAGCCATACAGGCCTGCCTTGTCGTCATCTTCTTTGTCTTCT
CCCTGGTCAGTCTTTCGATGGACGTGCTCATGGGCATCATCAATCCGAGGCGCCGCGATGTCTGA

Upstream 100 bases:

>100_bases
TCCGGCTGAGCATCGGGCTCGAGGACGAAAGGGATCTGCGCGAGGATCTGGACCGCATCTTCGGATATCTTGACGCGGCT
CTGGTGGAGACAGCCGCCCA

Downstream 100 bases:

>100_bases
TTCGAGTCTCACTTTCACTCGGCAGTCCGACTGGCGGGTCTGGTTCGCCATCCCCGTTCTGGCGGTAGCGGGCCTGTTCG
CCCTGCTGGGTGAATGGATC

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 314; Mature: 314

Protein sequence:

>314_residues
MNYYLRRLAVAIATVLISSSLVFFAIRILPGDPVMMLLGESAATPEVIARMAERLGMDAPLHVQYFRWLTDLLQLDFGTS
IGTGLPVANELIKRLPRSLELMAGGILVSLSIGIPLGVVAARRPDSFIGNAASVLALIGLSAPTFVKGLILIIIFSITLG
LLPSSGFTPFTQDPAANLRNLILPSLTLGLGFAGVVQRITRASLAETLGKDYVRTVRAKGVSENASVYRHALPNAMIPVI
AVVGIRIGSMLGGMVVIENLFNWPGLSSYLIEACYARDYPAIQACLVVIFFVFSLVSLSMDVLMGIINPRRRDV

Sequences:

>Translated_314_residues
MNYYLRRLAVAIATVLISSSLVFFAIRILPGDPVMMLLGESAATPEVIARMAERLGMDAPLHVQYFRWLTDLLQLDFGTS
IGTGLPVANELIKRLPRSLELMAGGILVSLSIGIPLGVVAARRPDSFIGNAASVLALIGLSAPTFVKGLILIIIFSITLG
LLPSSGFTPFTQDPAANLRNLILPSLTLGLGFAGVVQRITRASLAETLGKDYVRTVRAKGVSENASVYRHALPNAMIPVI
AVVGIRIGSMLGGMVVIENLFNWPGLSSYLIEACYARDYPAIQACLVVIFFVFSLVSLSMDVLMGIINPRRRDV
>Mature_314_residues
MNYYLRRLAVAIATVLISSSLVFFAIRILPGDPVMMLLGESAATPEVIARMAERLGMDAPLHVQYFRWLTDLLQLDFGTS
IGTGLPVANELIKRLPRSLELMAGGILVSLSIGIPLGVVAARRPDSFIGNAASVLALIGLSAPTFVKGLILIIIFSITLG
LLPSSGFTPFTQDPAANLRNLILPSLTLGLGFAGVVQRITRASLAETLGKDYVRTVRAKGVSENASVYRHALPNAMIPVI
AVVGIRIGSMLGGMVVIENLFNWPGLSSYLIEACYARDYPAIQACLVVIFFVFSLVSLSMDVLMGIINPRRRDV

Specific function: Part of the ABC transporter complex gsiABCD involved in glutathione import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787053, Length=312, Percent_Identity=40.0641025641026, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1789965, Length=336, Percent_Identity=36.0119047619048, Blast_Score=219, Evalue=2e-58,
Organism=Escherichia coli, GI1789888, Length=314, Percent_Identity=34.7133757961783, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1787761, Length=328, Percent_Identity=35.9756097560976, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787497, Length=313, Percent_Identity=30.9904153354633, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1787550, Length=278, Percent_Identity=31.294964028777, Blast_Score=131, Evalue=7e-32,
Organism=Escherichia coli, GI1788504, Length=355, Percent_Identity=28.4507042253521, Blast_Score=127, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 33769; Mature: 33769

Theoretical pI: Translated: 9.82; Mature: 9.82

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYYLRRLAVAIATVLISSSLVFFAIRILPGDPVMMLLGESAATPEVIARMAERLGMDAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
LHVQYFRWLTDLLQLDFGTSIGTGLPVANELIKRLPRSLELMAGGILVSLSIGIPLGVVA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHCCHHEEEECCCCHHHHH
ARRPDSFIGNAASVLALIGLSAPTFVKGLILIIIFSITLGLLPSSGFTPFTQDPAANLRN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LILPSLTLGLGFAGVVQRITRASLAETLGKDYVRTVRAKGVSENASVYRHALPNAMIPVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHH
AVVGIRIGSMLGGMVVIENLFNWPGLSSYLIEACYARDYPAIQACLVVIFFVFSLVSLSM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DVLMGIINPRRRDV
HHHHHHCCCCCCCC
>Mature Secondary Structure
MNYYLRRLAVAIATVLISSSLVFFAIRILPGDPVMMLLGESAATPEVIARMAERLGMDAP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCC
LHVQYFRWLTDLLQLDFGTSIGTGLPVANELIKRLPRSLELMAGGILVSLSIGIPLGVVA
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHHHHHHHCCHHEEEECCCCHHHHH
ARRPDSFIGNAASVLALIGLSAPTFVKGLILIIIFSITLGLLPSSGFTPFTQDPAANLRN
CCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
LILPSLTLGLGFAGVVQRITRASLAETLGKDYVRTVRAKGVSENASVYRHALPNAMIPVI
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHH
AVVGIRIGSMLGGMVVIENLFNWPGLSSYLIEACYARDYPAIQACLVVIFFVFSLVSLSM
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
DVLMGIINPRRRDV
HHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA