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The map label for this gene is ahpF [C]

Identifier: 110634555

GI number: 110634555

Start: 2355319

End: 2356209

Strand: Reverse

Name: ahpF [C]

Synonym: Meso_2206

Alternate gene names: 110634555

Gene position: 2356209-2355319 (Counterclockwise)

Preceding gene: 110634558

Following gene: 110634554

Centisome position: 53.4

GC content: 65.99

Gene sequence:

>891_bases
ATGGATTATGATGTGATCGTGGTCGGCGGCAGCTATGCCGGCCTTGCGGCGGCACTGCAGCTCGGGCGCGCACGCCGCCG
TGTGCTGGTGATAGACGAGGGACAGCCCCGCAACCGCTTTGCCAAGAGCTCCCACGGGTTTCTGACGCAGGACGGCGCAT
CTCCCAACGAGATCGCCGCACGCGGCCGCGCGGAAGTGATGGCCTACCCCACCGTGGAGTGGAAACAGGGCAGGGCCGAA
ACCGCGGGGAGGGGAGAGGAGGGCTTCCTCGTGGGAACTTCAACCGGCGACAGCTATGAAGCACGGCGCCTGATCCTCGC
AACCGGTGTCGTCGATGACCTGCCGCAGGTTCCCGGCCTCGCGGAGCGTTGGGGAAAGAGCGTCTTCCACTGCCCTTATT
GCCATGGGTACGAACTCGAAGGCGGACGCATCGGCGTGCTTGCCTCCCAGCCGGCGTCGATGCATCACGCGCTGCTGCTG
CCCGAGTGGGGCAAGACCATCTTCTTCCTCAACGGCATTTTTGCGCCGACCGAGAAAGAGCAGGCGGAGCTGAACCGGCG
CGACGTGGTGATGGAGACCGGATTGATCGAGAGGATCGACGGCGAGGCCGATGTTGTAATGAGCGACGGGAGGGTGTTCT
CGCCTGCCGCCCTCTTCACCGCCACGATCACGCGCCTTTCGGGCACGCTCGCCGAGCAGCTCGGCTGCGAGCTGGACCAG
GGAGCCGTCGGCACGTTCATCAAGACCAATTCCTTCAAGGAGACGTCTGTGCCGGGGGTGTTCGCCTGCGGTGATGCCGG
CCGGCCGGCGGGCTCCGTCCCGCTTGCCGTGGGCGAAGGAACCTTGGCGGGGATCGGGGCGCACCAGTCGCTGGTGTTTC
CGGAGGGGTAG

Upstream 100 bases:

>100_bases
CATTTCCCAGTGGCCGGGCGGGGATATCACTCTAGCTAAGCTTGCCACGGATATCGATCGGGCTCCGCTCATCGTTACAG
CCACAAGCAAAGGCATTCGA

Downstream 100 bases:

>100_bases
AGCAAACATCGGAAAAGGTTATCGCCGGCGTCGGCAATGCCTCTGACGTGCGGCTTGCCGCGGGCCTGCATTGTGATGGA
GCCCAAAACCGCCTATCTGA

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: an alcohol; H2O; NAD [C]

Alternate protein names: Thioredoxin Reductase; FAD-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Oxidoreductase; Reductase; Pyridine Nucleotide-Disulphide Oxidoreductase Class II; FAD Dependent Oxidoreductase; Pyridine Nucleotide-Disulphide Oxidoreductase; Thioredoxin-Disulfide Reductase; Pyridine Nucleotide-Disulfide Oxidoreductase; Thioredoxin Reductase Protein; Pyridine Nucleotide-Disulfide Oxidoreductase Domain Protein; Methyltransferase Type; Fad-Dependent Pyridine Nucleotide-Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase; Pyridine Nucleotide-Disulfide Oxidoreductase Family Protein; Oxidoreductase Protein; Methyltransferase; Disulfide Oxidoreductase; Alkyl Hydroperoxide Reductase Large Subunit

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MDYDVIVVGGSYAGLAAALQLGRARRRVLVIDEGQPRNRFAKSSHGFLTQDGASPNEIAARGRAEVMAYPTVEWKQGRAE
TAGRGEEGFLVGTSTGDSYEARRLILATGVVDDLPQVPGLAERWGKSVFHCPYCHGYELEGGRIGVLASQPASMHHALLL
PEWGKTIFFLNGIFAPTEKEQAELNRRDVVMETGLIERIDGEADVVMSDGRVFSPAALFTATITRLSGTLAEQLGCELDQ
GAVGTFIKTNSFKETSVPGVFACGDAGRPAGSVPLAVGEGTLAGIGAHQSLVFPEG

Sequences:

>Translated_296_residues
MDYDVIVVGGSYAGLAAALQLGRARRRVLVIDEGQPRNRFAKSSHGFLTQDGASPNEIAARGRAEVMAYPTVEWKQGRAE
TAGRGEEGFLVGTSTGDSYEARRLILATGVVDDLPQVPGLAERWGKSVFHCPYCHGYELEGGRIGVLASQPASMHHALLL
PEWGKTIFFLNGIFAPTEKEQAELNRRDVVMETGLIERIDGEADVVMSDGRVFSPAALFTATITRLSGTLAEQLGCELDQ
GAVGTFIKTNSFKETSVPGVFACGDAGRPAGSVPLAVGEGTLAGIGAHQSLVFPEG
>Mature_296_residues
MDYDVIVVGGSYAGLAAALQLGRARRRVLVIDEGQPRNRFAKSSHGFLTQDGASPNEIAARGRAEVMAYPTVEWKQGRAE
TAGRGEEGFLVGTSTGDSYEARRLILATGVVDDLPQVPGLAERWGKSVFHCPYCHGYELEGGRIGVLASQPASMHHALLL
PEWGKTIFFLNGIFAPTEKEQAELNRRDVVMETGLIERIDGEADVVMSDGRVFSPAALFTATITRLSGTLAEQLGCELDQ
GAVGTFIKTNSFKETSVPGVFACGDAGRPAGSVPLAVGEGTLAGIGAHQSLVFPEG

Specific function: Serves To Protect The Cell Against DNA Damage By Alkyl Hydroperoxides. It Can Use Either NADH Or NADPH As Electron Donor For Direct Reduction Of Redox Dyes Or Of Alkyl Hydroperoxides When Combined With The Ahpc Protein. [C]

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 1.6.4.- [C]

Molecular weight: Translated: 31421; Mature: 31421

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYDVIVVGGSYAGLAAALQLGRARRRVLVIDEGQPRNRFAKSSHGFLTQDGASPNEIAA
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCEEEECCCCHHHHHH
RGRAEVMAYPTVEWKQGRAETAGRGEEGFLVGTSTGDSYEARRLILATGVVDDLPQVPGL
CCCEEEEEECCCHHCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEEECCHHHCCCCCCH
AERWGKSVFHCPYCHGYELEGGRIGVLASQPASMHHALLLPEWGKTIFFLNGIFAPTEKE
HHHHCCCEEECCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEECEECCCCHH
QAELNRRDVVMETGLIERIDGEADVVMSDGRVFSPAALFTATITRLSGTLAEQLGCELDQ
HHHCCHHHEEECCCCHHHCCCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCC
GAVGTFIKTNSFKETSVPGVFACGDAGRPAGSVPLAVGEGTLAGIGAHQSLVFPEG
CCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEECCCCCEEECCCC
>Mature Secondary Structure
MDYDVIVVGGSYAGLAAALQLGRARRRVLVIDEGQPRNRFAKSSHGFLTQDGASPNEIAA
CCEEEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCEEEECCCCHHHHHH
RGRAEVMAYPTVEWKQGRAETAGRGEEGFLVGTSTGDSYEARRLILATGVVDDLPQVPGL
CCCEEEEEECCCHHCCCCCCCCCCCCCCEEEECCCCCCHHHEEEEEEECCHHHCCCCCCH
AERWGKSVFHCPYCHGYELEGGRIGVLASQPASMHHALLLPEWGKTIFFLNGIFAPTEKE
HHHHCCCEEECCCCCCEEECCCEEEEEECCCCCCCEEEEECCCCCEEEEEECEECCCCHH
QAELNRRDVVMETGLIERIDGEADVVMSDGRVFSPAALFTATITRLSGTLAEQLGCELDQ
HHHCCHHHEEECCCCHHHCCCCEEEEEECCCEECHHHHHHHHHHHHHHHHHHHHCCCCCC
GAVGTFIKTNSFKETSVPGVFACGDAGRPAGSVPLAVGEGTLAGIGAHQSLVFPEG
CCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCEEEECCCCEEECCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ROOH; Proton; NADH [C]

Specific reaction: ROOH + Proton + NADH = an alcohol + H2O + NAD [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA