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The map label for this gene is 110634550

Identifier: 110634550

GI number: 110634550

Start: 2349822

End: 2350949

Strand: Direct

Name: 110634550

Synonym: Meso_2201

Alternate gene names: NA

Gene position: 2349822-2350949 (Clockwise)

Preceding gene: 110634546

Following gene: 110634551

Centisome position: 53.25

GC content: 62.68

Gene sequence:

>1128_bases
ATGGCCTGGTCATTCAATATCGGTAAGTTCAGCGGCACCGTTGTGCGCGTGCATGTGACGTTCCTGCTGCTGCTCGTCTG
GATCTGGTTCATGCATTACCGGATCGGCGGCGCGGCCGCCGCATGGGAGGGCGTGGCCTTTATCATCGCGGTCTTCGCCT
GTGTCGTGCTGCACGAATTCGGCCATGCGTTCGCCGCCCGCCGATACGGCATCAAGACGCCAGATATCACACTTCTTCCG
ATCGGCGGGCTCGCCCGACTCGAGCGCATGCCGGAAGAGCCCGGCCAGGAATTTGTGATCGCGGTGGCGGGCCCGCTGGT
CAATGTGATTATCGCGGCGATTATTTTCCTAGCGGTGGGCGGTTCCGCCGGAATAGAGCAGATGATGCAGGTGGAAAATC
CGCGCACGAGCTTTCTCGTGCGGCTTGCCGGCGTGAACGTGTTTCTCGTGCTCTTCAACATGATCCCCGCCTTTCCCATG
GATGGCGGCAGGGTGTTGCGCGCCATTCTCGCCACGCGCATGACCTGGGCGCGCGCCACGCAGATCGCTGCCAATATCGG
CCAGGGGCTCGCCTTCCTGTTCGGCTTTCTCGGTCTATTCTACAATCCGCTGCTCATCTTCATCGCAATCTTCGTCTATC
TCGCCGCCGCCGCCGAGGCGCAGAACGCGCAGATCCGGGACATCTCAAACAGCGTGCTGACGGGCGATGTGATGGTGACG
GAATTCGCCTCTCTCGAGCGCTCATCGACCATCGCCGAGGCCATCGACCGCCTGCTGGCGACCACGCAGAGCGAATTCCC
CGTGCTCGACGCCGATGGTCATCTGACCGGTCTGCTCACCCGAAACGACATGATCGCCGCCTTGAAGGAGACAGGGCCCG
ACGCGCCGGTGGTGAGCGTGATGCGCACGGATGTGCCGAGCGTTCACCGTCTTCAGAGCCTTACTGACGGGTTCCGGCTG
ATGCAGGAGAAAAGCGCGCCCGCCGTCGCCGTGGTGGACAGCGGCGGCCGGCTTGTCGGCTTGCTCACGCACGAGACCAT
TGGCGAAATGATGATGGTGCGCGCGGCCATGCCAGAGGGCTTTCGCTTCGGCCGTTTGCGGCAGACCCCCTTCATTCGCC
GTCCTTGA

Upstream 100 bases:

>100_bases
TTCATTGAGCCTCCATCATTTCAGCGGCTTGAAAATAACGTCGTCGTTCCAAATGTCTTTAATATGTATTTCTCATCCAT
TCCGGCAGGGGCGCGGCAAC

Downstream 100 bases:

>100_bases
CATTGAAAGTCCGGTGGCCCAAGTTAAACCTATGAGCGAAACCGCACCCCGCATATTCTTTCTTTTTAGGGTCTGTCCCA
TCGCCGGACACTAACCCCGG

Product: peptidase M50

Products: NA

Alternate protein names: Site-2-type intermembrane protease [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MAWSFNIGKFSGTVVRVHVTFLLLLVWIWFMHYRIGGAAAAWEGVAFIIAVFACVVLHEFGHAFAARRYGIKTPDITLLP
IGGLARLERMPEEPGQEFVIAVAGPLVNVIIAAIIFLAVGGSAGIEQMMQVENPRTSFLVRLAGVNVFLVLFNMIPAFPM
DGGRVLRAILATRMTWARATQIAANIGQGLAFLFGFLGLFYNPLLIFIAIFVYLAAAAEAQNAQIRDISNSVLTGDVMVT
EFASLERSSTIAEAIDRLLATTQSEFPVLDADGHLTGLLTRNDMIAALKETGPDAPVVSVMRTDVPSVHRLQSLTDGFRL
MQEKSAPAVAVVDSGGRLVGLLTHETIGEMMMVRAAMPEGFRFGRLRQTPFIRRP

Sequences:

>Translated_375_residues
MAWSFNIGKFSGTVVRVHVTFLLLLVWIWFMHYRIGGAAAAWEGVAFIIAVFACVVLHEFGHAFAARRYGIKTPDITLLP
IGGLARLERMPEEPGQEFVIAVAGPLVNVIIAAIIFLAVGGSAGIEQMMQVENPRTSFLVRLAGVNVFLVLFNMIPAFPM
DGGRVLRAILATRMTWARATQIAANIGQGLAFLFGFLGLFYNPLLIFIAIFVYLAAAAEAQNAQIRDISNSVLTGDVMVT
EFASLERSSTIAEAIDRLLATTQSEFPVLDADGHLTGLLTRNDMIAALKETGPDAPVVSVMRTDVPSVHRLQSLTDGFRL
MQEKSAPAVAVVDSGGRLVGLLTHETIGEMMMVRAAMPEGFRFGRLRQTPFIRRP
>Mature_374_residues
AWSFNIGKFSGTVVRVHVTFLLLLVWIWFMHYRIGGAAAAWEGVAFIIAVFACVVLHEFGHAFAARRYGIKTPDITLLPI
GGLARLERMPEEPGQEFVIAVAGPLVNVIIAAIIFLAVGGSAGIEQMMQVENPRTSFLVRLAGVNVFLVLFNMIPAFPMD
GGRVLRAILATRMTWARATQIAANIGQGLAFLFGFLGLFYNPLLIFIAIFVYLAAAAEAQNAQIRDISNSVLTGDVMVTE
FASLERSSTIAEAIDRLLATTQSEFPVLDADGHLTGLLTRNDMIAALKETGPDAPVVSVMRTDVPSVHRLQSLTDGFRLM
QEKSAPAVAVVDSGGRLVGLLTHETIGEMMMVRAAMPEGFRFGRLRQTPFIRRP

Specific function: Unknown

COG id: COG1994

COG function: function code R; Zn-dependent proteases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000644
- InterPro:   IPR008915
- InterPro:   IPR016483 [H]

Pfam domain/function: PF00571 CBS; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 40832; Mature: 40700

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWSFNIGKFSGTVVRVHVTFLLLLVWIWFMHYRIGGAAAAWEGVAFIIAVFACVVLHEF
CCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GHAFAARRYGIKTPDITLLPIGGLARLERMPEEPGQEFVIAVAGPLVNVIIAAIIFLAVG
HHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
GSAGIEQMMQVENPRTSFLVRLAGVNVFLVLFNMIPAFPMDGGRVLRAILATRMTWARAT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QIAANIGQGLAFLFGFLGLFYNPLLIFIAIFVYLAAAAEAQNAQIRDISNSVLTGDVMVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECHHHHH
EFASLERSSTIAEAIDRLLATTQSEFPVLDADGHLTGLLTRNDMIAALKETGPDAPVVSV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEECCHHHHHHHHCCCCCHHHHH
MRTDVPSVHRLQSLTDGFRLMQEKSAPAVAVVDSGGRLVGLLTHETIGEMMMVRAAMPEG
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCC
FRFGRLRQTPFIRRP
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
AWSFNIGKFSGTVVRVHVTFLLLLVWIWFMHYRIGGAAAAWEGVAFIIAVFACVVLHEF
CEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
GHAFAARRYGIKTPDITLLPIGGLARLERMPEEPGQEFVIAVAGPLVNVIIAAIIFLAVG
HHHHHHHHCCCCCCCEEEEECCHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHCC
GSAGIEQMMQVENPRTSFLVRLAGVNVFLVLFNMIPAFPMDGGRVLRAILATRMTWARAT
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
QIAANIGQGLAFLFGFLGLFYNPLLIFIAIFVYLAAAAEAQNAQIRDISNSVLTGDVMVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCEECHHHHH
EFASLERSSTIAEAIDRLLATTQSEFPVLDADGHLTGLLTRNDMIAALKETGPDAPVVSV
HHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEEEECCHHHHHHHHCCCCCHHHHH
MRTDVPSVHRLQSLTDGFRLMQEKSAPAVAVVDSGGRLVGLLTHETIGEMMMVRAAMPEG
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHCCCC
FRFGRLRQTPFIRRP
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]