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The map label for this gene is fbcH [H]

Identifier: 110634513

GI number: 110634513

Start: 2313859

End: 2314704

Strand: Reverse

Name: fbcH [H]

Synonym: Meso_2164

Alternate gene names: 110634513

Gene position: 2314704-2313859 (Counterclockwise)

Preceding gene: 110634514

Following gene: 110634512

Centisome position: 52.46

GC content: 61.23

Gene sequence:

>846_bases
ATGAGAATGTTTCTCCACGCTCTGGGGGCTCTCGGGCTTGGTCTTGCGCTCGCCACCTCAGCCGGGGCTCAGGAAGAAGA
AGCGACGCCGCATTATCCGCTGCACCATCCCGAACCGCAGGAATGGTCTTTTGCGGGGCCGTTCGGAACCTATGACAAGG
GGCAGTTGCAGCGCGGCTTCAAGGTCTATCGCGAGGTTTGCTCCGCCTGCCATTCACTCGACATGGTGGCGTTCCGCAAC
CTGGAGGCTCTGGGCTATTCGGATGAGCAGGTGCGCGCCATCGCGGCCGAGTACCAGATACAGGATGGTCCGAACGAGGC
GGGCGACATGTTCGAGCGTCCCGGCACGCCTTCGGACTATTTCCCGTCGCCATTCGCCAACCCGGAGCAGGCAGCGGCAT
CCAATAACGGCGCTCCCCCACCCGATCTATCGTTGATCGCCAAGGCGCGCGGCGTGGAGCGCGGGTTCCCGACCTTCATC
TTCGATATCTTCACGCAATACGCCGAAGGCGGGCCGGACTACATCCATGCTCTGTTGACGGGCTATGACGAAGCCCCGCC
GGAGGGGCTCCAGGTTCCTGAAGGCACCTATTACAATCCTTATTTCATCAGCGGTCCGGCTCTTGCCATGCCGCCTCCGA
TCTCCGACGGCCAGGTGACCTATGACGACGGGGCTCCTGAAACGGTCGATCAGTATTCCCGCGACGTCTCGGCATTCCTG
ATGTGGGCTGCGGAGCCGCATCTGGAGGCACGTAAGCAGACCGGCTTCACGGTGGTGATTTTCCTGCTCCTTTTCGGAGG
GCTGGTCTATCTCACCAAACGCAAGATCTGGGCCGAACTGCACTAG

Upstream 100 bases:

>100_bases
CAACTCGATCACCGAGGCGGTGCTGGAGAAGAACAAGGCCGGTTCCTTGGCCGCCCAGCCGGTCAGCCAACGCTAAGCGA
TGCGCAAGGGGATTTTGGAA

Downstream 100 bases:

>100_bases
CAGTAGGCCTGAAATCGGAACAAAGGGCGCCGAGTGGCGCCCTTTTCTTTGCCGGCAGGAAGAGGCACAAAAGGACAAAC
GGGGGACTTGGCCTCAATGA

Product: cytochrome c1

Products: Q; ferrocytochrome c

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MRMFLHALGALGLGLALATSAGAQEEEATPHYPLHHPEPQEWSFAGPFGTYDKGQLQRGFKVYREVCSACHSLDMVAFRN
LEALGYSDEQVRAIAAEYQIQDGPNEAGDMFERPGTPSDYFPSPFANPEQAAASNNGAPPPDLSLIAKARGVERGFPTFI
FDIFTQYAEGGPDYIHALLTGYDEAPPEGLQVPEGTYYNPYFISGPALAMPPPISDGQVTYDDGAPETVDQYSRDVSAFL
MWAAEPHLEARKQTGFTVVIFLLLFGGLVYLTKRKIWAELH

Sequences:

>Translated_281_residues
MRMFLHALGALGLGLALATSAGAQEEEATPHYPLHHPEPQEWSFAGPFGTYDKGQLQRGFKVYREVCSACHSLDMVAFRN
LEALGYSDEQVRAIAAEYQIQDGPNEAGDMFERPGTPSDYFPSPFANPEQAAASNNGAPPPDLSLIAKARGVERGFPTFI
FDIFTQYAEGGPDYIHALLTGYDEAPPEGLQVPEGTYYNPYFISGPALAMPPPISDGQVTYDDGAPETVDQYSRDVSAFL
MWAAEPHLEARKQTGFTVVIFLLLFGGLVYLTKRKIWAELH
>Mature_281_residues
MRMFLHALGALGLGLALATSAGAQEEEATPHYPLHHPEPQEWSFAGPFGTYDKGQLQRGFKVYREVCSACHSLDMVAFRN
LEALGYSDEQVRAIAAEYQIQDGPNEAGDMFERPGTPSDYFPSPFANPEQAAASNNGAPPPDLSLIAKARGVERGFPTFI
FDIFTQYAEGGPDYIHALLTGYDEAPPEGLQVPEGTYYNPYFISGPALAMPPPISDGQVTYDDGAPETVDQYSRDVSAFL
MWAAEPHLEARKQTGFTVVIFLLLFGGLVYLTKRKIWAELH

Specific function: Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. c1 functions as an electron donor to cytochrome c [H]

COG id: COG2857

COG function: function code C; Cytochrome c1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Homo sapiens, GI21359867, Length=245, Percent_Identity=44.8979591836735, Blast_Score=210, Evalue=1e-54,
Organism=Caenorhabditis elegans, GI17506225, Length=272, Percent_Identity=37.1323529411765, Blast_Score=148, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6324639, Length=272, Percent_Identity=43.3823529411765, Blast_Score=210, Evalue=2e-55,
Organism=Drosophila melanogaster, GI21358225, Length=285, Percent_Identity=38.9473684210526, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24658292, Length=279, Percent_Identity=38.7096774193548, Blast_Score=191, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016175
- InterPro:   IPR005798
- InterPro:   IPR005797
- InterPro:   IPR002326
- InterPro:   IPR021157
- InterPro:   IPR009056
- InterPro:   IPR016174 [H]

Pfam domain/function: PF00032 Cytochrom_B_C; PF00033 Cytochrom_B_N; PF02167 Cytochrom_C1 [H]

EC number: 1.10.2.2

Molecular weight: Translated: 30843; Mature: 30843

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMFLHALGALGLGLALATSAGAQEEEATPHYPLHHPEPQEWSFAGPFGTYDKGQLQRGF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
KVYREVCSACHSLDMVAFRNLEALGYSDEQVRAIAAEYQIQDGPNEAGDMFERPGTPSDY
HHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
FPSPFANPEQAAASNNGAPPPDLSLIAKARGVERGFPTFIFDIFTQYAEGGPDYIHALLT
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
GYDEAPPEGLQVPEGTYYNPYFISGPALAMPPPISDGQVTYDDGAPETVDQYSRDVSAFL
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
MWAAEPHLEARKQTGFTVVIFLLLFGGLVYLTKRKIWAELH
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRMFLHALGALGLGLALATSAGAQEEEATPHYPLHHPEPQEWSFAGPFGTYDKGQLQRGF
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
KVYREVCSACHSLDMVAFRNLEALGYSDEQVRAIAAEYQIQDGPNEAGDMFERPGTPSDY
HHHHHHHHHHHHHHHHHHHCHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCC
FPSPFANPEQAAASNNGAPPPDLSLIAKARGVERGFPTFIFDIFTQYAEGGPDYIHALLT
CCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHH
GYDEAPPEGLQVPEGTYYNPYFISGPALAMPPPISDGQVTYDDGAPETVDQYSRDVSAFL
CCCCCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHH
MWAAEPHLEARKQTGFTVVIFLLLFGGLVYLTKRKIWAELH
HHHCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: QH2; ferricytochrome c

Specific reaction: QH2 + 2 ferricytochrome c = Q + 2 ferrocytochrome c

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2541921; 12597275 [H]