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The map label for this gene is engD [H]

Identifier: 110634508

GI number: 110634508

Start: 2309156

End: 2310259

Strand: Direct

Name: engD [H]

Synonym: Meso_2159

Alternate gene names: 110634508

Gene position: 2309156-2310259 (Clockwise)

Preceding gene: 110634507

Following gene: 110634509

Centisome position: 52.33

GC content: 61.96

Gene sequence:

>1104_bases
ATGGGTTTCAAATGCGGCATCGTCGGCTTGCCCAATGTCGGCAAATCGACGCTCTTTAATGCGCTGACCAAGACAGCTGC
CGCCCAGGCCGCGAATTATCCCTTCTGCACCATCGAGCCCAATACGGGCGAGGTGGCCGTGCCCGACCCGCGCCTGAAAA
AGATCGCCGAGATCGCGGCATCCAAGGAGACCGTGCCGACGCGCATTTCCTTCGTCGATATTGCCGGCCTCGTGCGCGGC
GCCTCCAAGGGCGAAGGGCTCGGCAACCAGTTCCTCGCCAATATTCGCGAGGTGGACGCCGTCGTGCATGTGCTGCGCTG
CTTTGAGGACGACGACATCACCCATGTGGAGGGCCGCATCGATCCGGTAGCCGATGCCGATACGGTTGAAACCGAGTTGA
TGCTGGCGGATCTGGAAAGCCTTGAGCGGCGCATCGTGCAGGTCAGGAAGCGCGCCACCGGCAAGGAAAAGGAGGCTATG
TCCATCCTTCCCGTAATGGAAGAAGCGCTCAAGCTGCTTCAGGACGGCAAGCCGGTACGCCTCGTTGCGGCGGAGCTCGA
CCCGGAGGGAATGCGGATCCTCCGCTCGCTCAACCTGCTTACTTCCAAGCCGGTGCTCTATGTCTGCAATGTCGCAGAAG
GTGACGCGGCGACGGGCAATGCTCACACATCGGCCGTCGAGAAAATGGCCGAGGCACAGGGCGCCAGGACCGTAATCATC
TCCGCCGCGATCGAGGCCGAGGTGGCCCAGCTGCCTCAAGAGGAAGCTGCCGAGTATCTGGAAGCCATGGGCTTGCATGA
GCCCGGGCTCGACCGGCTCATCCGTGCCGGCTATGAGCTTTTGGACCTCATAACCTTCTTCACCGCCGGCCCGAAGGAAG
CCCGAGCCTGGACCGTGCAGAAGGGAGCCAAGGCGCCTCAGGCAGCCGGCGTGATCCATACGGATTTCGAGCGCGGCTTC
ATTCGGGCGCAAACGATCGCCTATGACGATTTCGTGCAGCTGGGCGGCGAAACCGCCGCACGGGAGGCCGGAAAGGCGCG
CGACGAAGGCAAGGACTATGTCGTGCAGGACGGCGATGTCATGCTGTTCAAATTCAACGTGTAA

Upstream 100 bases:

>100_bases
TTTGAAAGCTTTTCCGGGCTTGACGATGGTCGGTTCCTTCGCCCATAGCCCCTCCCAGCATTACTTGAACGGCTACCAAA
AACGACAGGACAGATAATCC

Downstream 100 bases:

>100_bases
AGCGCGCTACGTTCCCGAAGACCGGGTCTGGTCGAGGATTCCCGAATGACCAAGCCATGGGCCTATGAGGACATGACGGA
GGGCCGGGTGTTCGACCTCG

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRLKKIAEIAASKETVPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAVVHVLRCFEDDDITHVEGRIDPVADADTVETELMLADLESLERRIVQVRKRATGKEKEAM
SILPVMEEALKLLQDGKPVRLVAAELDPEGMRILRSLNLLTSKPVLYVCNVAEGDAATGNAHTSAVEKMAEAQGARTVII
SAAIEAEVAQLPQEEAAEYLEAMGLHEPGLDRLIRAGYELLDLITFFTAGPKEARAWTVQKGAKAPQAAGVIHTDFERGF
IRAQTIAYDDFVQLGGETAAREAGKARDEGKDYVVQDGDVMLFKFNV

Sequences:

>Translated_367_residues
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRLKKIAEIAASKETVPTRISFVDIAGLVRG
ASKGEGLGNQFLANIREVDAVVHVLRCFEDDDITHVEGRIDPVADADTVETELMLADLESLERRIVQVRKRATGKEKEAM
SILPVMEEALKLLQDGKPVRLVAAELDPEGMRILRSLNLLTSKPVLYVCNVAEGDAATGNAHTSAVEKMAEAQGARTVII
SAAIEAEVAQLPQEEAAEYLEAMGLHEPGLDRLIRAGYELLDLITFFTAGPKEARAWTVQKGAKAPQAAGVIHTDFERGF
IRAQTIAYDDFVQLGGETAAREAGKARDEGKDYVVQDGDVMLFKFNV
>Mature_366_residues
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRLKKIAEIAASKETVPTRISFVDIAGLVRGA
SKGEGLGNQFLANIREVDAVVHVLRCFEDDDITHVEGRIDPVADADTVETELMLADLESLERRIVQVRKRATGKEKEAMS
ILPVMEEALKLLQDGKPVRLVAAELDPEGMRILRSLNLLTSKPVLYVCNVAEGDAATGNAHTSAVEKMAEAQGARTVIIS
AAIEAEVAQLPQEEAAEYLEAMGLHEPGLDRLIRAGYELLDLITFFTAGPKEARAWTVQKGAKAPQAAGVIHTDFERGFI
RAQTIAYDDFVQLGGETAAREAGKARDEGKDYVVQDGDVMLFKFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=368, Percent_Identity=44.5652173913043, Blast_Score=309, Evalue=3e-84,
Organism=Homo sapiens, GI58761502, Length=198, Percent_Identity=42.9292929292929, Blast_Score=166, Evalue=4e-41,
Organism=Escherichia coli, GI1787454, Length=367, Percent_Identity=57.7656675749319, Blast_Score=430, Evalue=1e-122,
Organism=Escherichia coli, GI1789574, Length=145, Percent_Identity=32.4137931034483, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=42.7027027027027, Blast_Score=295, Evalue=2e-80,
Organism=Saccharomyces cerevisiae, GI6319499, Length=375, Percent_Identity=39.7333333333333, Blast_Score=272, Evalue=8e-74,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=36.9393139841689, Blast_Score=240, Evalue=2e-64,
Organism=Saccharomyces cerevisiae, GI6321649, Length=291, Percent_Identity=28.8659793814433, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24640873, Length=369, Percent_Identity=42.2764227642276, Blast_Score=287, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24640877, Length=369, Percent_Identity=42.2764227642276, Blast_Score=287, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24640875, Length=369, Percent_Identity=42.2764227642276, Blast_Score=287, Evalue=6e-78,
Organism=Drosophila melanogaster, GI24640879, Length=329, Percent_Identity=39.8176291793313, Blast_Score=233, Evalue=1e-61,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39589; Mature: 39457

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRLKKIAEIAA
CCEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKETVPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAVVHVLRCFEDDDITHVEGRI
CCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
DPVADADTVETELMLADLESLERRIVQVRKRATGKEKEAMSILPVMEEALKLLQDGKPVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LVAAELDPEGMRILRSLNLLTSKPVLYVCNVAEGDAATGNAHTSAVEKMAEAQGARTVII
EEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
SAAIEAEVAQLPQEEAAEYLEAMGLHEPGLDRLIRAGYELLDLITFFTAGPKEARAWTVQ
EHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHH
KGAKAPQAAGVIHTDFERGFIRAQTIAYDDFVQLGGETAAREAGKARDEGKDYVVQDGDV
CCCCCCCCCCCEEECHHCCEEEHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEECCCE
MLFKFNV
EEEEECC
>Mature Secondary Structure 
GFKCGIVGLPNVGKSTLFNALTKTAAAQAANYPFCTIEPNTGEVAVPDPRLKKIAEIAA
CEEECEEECCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEECCCHHHHHHHHHHH
SKETVPTRISFVDIAGLVRGASKGEGLGNQFLANIREVDAVVHVLRCFEDDDITHVEGRI
CCCCCCCEEHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCC
DPVADADTVETELMLADLESLERRIVQVRKRATGKEKEAMSILPVMEEALKLLQDGKPVR
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCEE
LVAAELDPEGMRILRSLNLLTSKPVLYVCNVAEGDAATGNAHTSAVEKMAEAQGARTVII
EEEECCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEE
SAAIEAEVAQLPQEEAAEYLEAMGLHEPGLDRLIRAGYELLDLITFFTAGPKEARAWTVQ
EHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHEEEHH
KGAKAPQAAGVIHTDFERGFIRAQTIAYDDFVQLGGETAAREAGKARDEGKDYVVQDGDV
CCCCCCCCCCCEEECHHCCEEEHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCEEEECCCE
MLFKFNV
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA