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The map label for this gene is ytfL [C]

Identifier: 110634471

GI number: 110634471

Start: 2277946

End: 2279256

Strand: Direct

Name: ytfL [C]

Synonym: Meso_2122

Alternate gene names: 110634471

Gene position: 2277946-2279256 (Clockwise)

Preceding gene: 110634470

Following gene: 110634473

Centisome position: 51.63

GC content: 62.32

Gene sequence:

>1311_bases
ATGCTCTTTGTTGAAATCGCCATTCTTCTCGCCCTTATTCTCTTTAATGGCTTTATGGCCATGTCGGAACTGGCCGTCGT
ATCCGCCCGTCCCGCACGTCTGAAGGCCCGCAGTGACAGGGGCGATCGAGGCGCCGCGCGATCCCTGGAGCTCTCCTCTG
AGCCGGGCCGATTTCTTTCCACCGTTCAGATCGGCATTACGCTCGTGGGGGTGCTTTCCGGCGCCTTTTCCGGGGCGACG
ATCGGCGTGCGCCTATCCGCCTGGCTGGCGGGCCTTGGAATGCCCGGAAGCATCGCCAATCCCCTGGGTGTCGGCATTGT
CGTGGCACTCATCACCTATGTCTCGCTTGTGATCGGTGAATTGGTGCCGAAGCAGGTGGCGCTGAAACATGCCGAGACGA
TAGCGGCAAAGGTGGCGCCCTTCATGGCTATGCTCGCCAAGGTCGCCCTTCCGCTCGTCTGGTTGCTGGACATATCCGGC
CGTGGCGTTCTTGCGCTGCTTGGGCAGGGATCGGAGGAAGCGAACCGCGTCACCGACGAGGAGATCAGAACGCTTATCGC
GGAAGCGGAGCATACGGGGACGATCGAGACCGAAGAAAAGCACATGATCGCCGGCGTGATGCGGCTTGCCGACCGAAACG
CCCGCGCGATCATGACCCCCAGGGGGGACGTGGACTGGCTGAACCTCCTCGCTCCCGACGAAGCGATCGAGAAGATGCTG
CGCGAAACGCCGCATACGCGCTTGCCTGCCGCCGAGGGTTCGGTGGACAAGCTGATCGGCGTCGTTAAAACCCGCGACTT
GCTAGTCGCATACCTGACGGAAGAAAAAGTCGATCCGGCCAGCTTCGTCCGGCCCGCCCCCATCGTTCACGATTTCGCCG
ATGCCCTCGACGTGCTCGTAACCTTGCGTCAGGCGGAAGTTCCCATGGCACTAGTCCATGACGAATACGGGACGTTCGAG
GGGGTCATCACCCCCGCCGACATCCTGGGCGCCATCGCGGGCGTATTCCGGGCGGATATCGATGAAGGCGAGGCCGATGT
CGTGCAGCGGGAGGACGGCTCCTGGCTGCTGCCTGGCCTCATGCCGGCCGATGAGATGGCCGACCGCCTCAGCATCAAGC
TTCCCGAGGACCGCGGCTACAGCACGCTTGCGGGTTTCCTGCTCTCATACACACAGGAGCTCCCTGTGACGGGGACAGTG
GTGGAAACGATGGGCTGGCGTTTCGAAGTCGTTGATATGGACGGCCGGCGAGTCGACCGCGTGCTGGCCAGCAAGACCGA
TGGTTCCGCAGGGATCGAAAACATCGAGTAG

Upstream 100 bases:

>100_bases
GAACGGCTATCGCGCCTGCAGGTAGCAGGACCATCCGCAATGTCCTATCTTGGCGCGGGTAGCTTCTGCTGAGCCATCAC
GCTCCCAACCAGAGTCAATC

Downstream 100 bases:

>100_bases
GATCAACTTGCAGCAAGTCGCCTCCTCCGGCTGGCAAGCCGGAGGAGGCGGGGGCAAAGATGAACCTGCGGCAAATACGT
TACGCTGCCTGTGCTTCCTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MLFVEIAILLALILFNGFMAMSELAVVSARPARLKARSDRGDRGAARSLELSSEPGRFLSTVQIGITLVGVLSGAFSGAT
IGVRLSAWLAGLGMPGSIANPLGVGIVVALITYVSLVIGELVPKQVALKHAETIAAKVAPFMAMLAKVALPLVWLLDISG
RGVLALLGQGSEEANRVTDEEIRTLIAEAEHTGTIETEEKHMIAGVMRLADRNARAIMTPRGDVDWLNLLAPDEAIEKML
RETPHTRLPAAEGSVDKLIGVVKTRDLLVAYLTEEKVDPASFVRPAPIVHDFADALDVLVTLRQAEVPMALVHDEYGTFE
GVITPADILGAIAGVFRADIDEGEADVVQREDGSWLLPGLMPADEMADRLSIKLPEDRGYSTLAGFLLSYTQELPVTGTV
VETMGWRFEVVDMDGRRVDRVLASKTDGSAGIENIE

Sequences:

>Translated_436_residues
MLFVEIAILLALILFNGFMAMSELAVVSARPARLKARSDRGDRGAARSLELSSEPGRFLSTVQIGITLVGVLSGAFSGAT
IGVRLSAWLAGLGMPGSIANPLGVGIVVALITYVSLVIGELVPKQVALKHAETIAAKVAPFMAMLAKVALPLVWLLDISG
RGVLALLGQGSEEANRVTDEEIRTLIAEAEHTGTIETEEKHMIAGVMRLADRNARAIMTPRGDVDWLNLLAPDEAIEKML
RETPHTRLPAAEGSVDKLIGVVKTRDLLVAYLTEEKVDPASFVRPAPIVHDFADALDVLVTLRQAEVPMALVHDEYGTFE
GVITPADILGAIAGVFRADIDEGEADVVQREDGSWLLPGLMPADEMADRLSIKLPEDRGYSTLAGFLLSYTQELPVTGTV
VETMGWRFEVVDMDGRRVDRVLASKTDGSAGIENIE
>Mature_436_residues
MLFVEIAILLALILFNGFMAMSELAVVSARPARLKARSDRGDRGAARSLELSSEPGRFLSTVQIGITLVGVLSGAFSGAT
IGVRLSAWLAGLGMPGSIANPLGVGIVVALITYVSLVIGELVPKQVALKHAETIAAKVAPFMAMLAKVALPLVWLLDISG
RGVLALLGQGSEEANRVTDEEIRTLIAEAEHTGTIETEEKHMIAGVMRLADRNARAIMTPRGDVDWLNLLAPDEAIEKML
RETPHTRLPAAEGSVDKLIGVVKTRDLLVAYLTEEKVDPASFVRPAPIVHDFADALDVLVTLRQAEVPMALVHDEYGTFE
GVITPADILGAIAGVFRADIDEGEADVVQREDGSWLLPGLMPADEMADRLSIKLPEDRGYSTLAGFLLSYTQELPVTGTV
VETMGWRFEVVDMDGRRVDRVLASKTDGSAGIENIE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=379, Percent_Identity=26.1213720316623, Blast_Score=164, Evalue=1e-40,
Organism=Escherichia coli, GI1790664, Length=429, Percent_Identity=26.3403263403263, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI145693175, Length=411, Percent_Identity=26.0340632603406, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87082033, Length=280, Percent_Identity=30, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1788119, Length=267, Percent_Identity=34.0823970037453, Blast_Score=119, Evalue=4e-28,
Organism=Escherichia coli, GI1786879, Length=270, Percent_Identity=26.6666666666667, Blast_Score=75, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 46762; Mature: 46762

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFVEIAILLALILFNGFMAMSELAVVSARPARLKARSDRGDRGAARSLELSSEPGRFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEECCCCCCHHHH
TVQIGITLVGVLSGAFSGATIGVRLSAWLAGLGMPGSIANPLGVGIVVALITYVSLVIGE
HHHHHHHHHHHHHCCCCCCEEHEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVPKQVALKHAETIAAKVAPFMAMLAKVALPLVWLLDISGRGVLALLGQGSEEANRVTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHCCCHH
EIRTLIAEAEHTGTIETEEKHMIAGVMRLADRNARAIMTPRGDVDWLNLLAPDEAIEKML
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCHHHHHHHH
RETPHTRLPAAEGSVDKLIGVVKTRDLLVAYLTEEKVDPASFVRPAPIVHDFADALDVLV
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
TLRQAEVPMALVHDEYGTFEGVITPADILGAIAGVFRADIDEGEADVVQREDGSWLLPGL
HHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEECCCCEECCCC
MPADEMADRLSIKLPEDRGYSTLAGFLLSYTQELPVTGTVVETMGWRFEVVDMDGRRVDR
CCHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCCHHHHH
VLASKTDGSAGIENIE
HHHCCCCCCCCCCCCC
>Mature Secondary Structure
MLFVEIAILLALILFNGFMAMSELAVVSARPARLKARSDRGDRGAARSLELSSEPGRFLS
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCEECCCCCCHHHH
TVQIGITLVGVLSGAFSGATIGVRLSAWLAGLGMPGSIANPLGVGIVVALITYVSLVIGE
HHHHHHHHHHHHHCCCCCCEEHEEHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
LVPKQVALKHAETIAAKVAPFMAMLAKVALPLVWLLDISGRGVLALLGQGSEEANRVTDE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCHHHHCCCHH
EIRTLIAEAEHTGTIETEEKHMIAGVMRLADRNARAIMTPRGDVDWLNLLAPDEAIEKML
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCHHHHCCCHHHHHHHH
RETPHTRLPAAEGSVDKLIGVVKTRDLLVAYLTEEKVDPASFVRPAPIVHDFADALDVLV
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHH
TLRQAEVPMALVHDEYGTFEGVITPADILGAIAGVFRADIDEGEADVVQREDGSWLLPGL
HHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEECCCCEECCCC
MPADEMADRLSIKLPEDRGYSTLAGFLLSYTQELPVTGTVVETMGWRFEVVDMDGRRVDR
CCHHHHHHHCEEECCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCEEEEEECCCHHHHH
VLASKTDGSAGIENIE
HHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]