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The map label for this gene is fusA [C]

Identifier: 110634459

GI number: 110634459

Start: 2265808

End: 2267823

Strand: Direct

Name: fusA [C]

Synonym: Meso_2110

Alternate gene names: 110634459

Gene position: 2265808-2267823 (Clockwise)

Preceding gene: 110634458

Following gene: 110634462

Centisome position: 51.35

GC content: 61.46

Gene sequence:

>2016_bases
ATGGGTAACCGAGCCGGAGACAGGTTCAAGGGACCGAAATGCATCGCCATTCTCGGTCCCCTTGCCAGCGGAAAGACAAC
GCTTTTTGAAGCCATCCTGCGACGCACGGGCGCGATTTCGGGCCAAGGCGGCCCCAGCGCAGACACACGCACCCACACGA
TGAGCGTCGAAGCGAGCTTTGCCACCACGAGCTTCATGGGAGAAAGCATCACCTTCGTCGATTGTCCCGGTTCCATCGAA
TTCGCCGAGGAGGCCGGGCCGGTATTGGCTGCCGCCGACGCAGCGGTGGTCGTGATCGATGCGGAGGACCACAAGCTTCC
GATGCTCCAGCTTATCCTGCGCCGGCTGGACGATATCGGCATTCCCCGCATGCTGTTTCTGAACAAGCTGGACAAGAGCG
CCATTGGCGTGCGCGAAACATTGAAGGCGCTGCAGCCCGCCAGCAGTCCGCCGCTGCTCCTGCGCCATATACCGCTGCGC
AAGAACGGCCTTTTGATCGGCTCCATCGATCTGGCTCTTGAGCGGGCCTACATCTATCGCGAGCACGCTGAAAGCGAGAT
CGCCCCCATCCCCGATGACGAGAAGGCACGGGAGATCGAAGCTCGCTTTTCCATGCTGGAAACGCTGGCCGATCATGACG
ACCAGCTGATGGAGCAGCTATTGGAGGAGATCGAGCCGCCGCGCGATGCGATTTTCGACGATCTGGCGGCGGATGTGCGT
GAAGGCACCGTCACGCCGGTCCTGATAGGCTCGGCCGAAAAAGGCAACGGCATCTTGCGGCTTTTAAAGGCGATCAGGCA
TGACGTGGCCGACGTGACGGAGACGCGAAAGCGGCTGGGCCATTCAAATGGTGATGGCAGCGCAACCCTGCAGGTGATGA
AGACGATTCATACCGGTCACGGCGGCAAGATTTCGGTCTGCCGCATTCTCTCCGGCACCATAAATGATGGCACGGAGCTT
CCGGATGCCGGCAGGATTTCGGGTATATACAGCCTCATAGGCCGGGACCAGACAAAGCTTGCCTCCGCAGGTGAAGGCGA
CACTGTGGCCCTCGGAAAACTCGATGGCGCTACCACCGGCGATACGCTTTCGACAAGCAAGGGCGCCGCCCGGCAGCTCG
CCAAACCGACTCCGCCCCATCCAGTCTTTGTTGTGGCTGTCAGCCCACGCGATCGCAAGGACGAGGTGAAGCTTTCAGCC
GCGCTCCAGAAGCTTCAGGAGGAAGATCCTTCCCTGCTCTTGCAGCAAAGCCAGGATACGGCCGAGACGATCCTGGGAGG
CCAGGGCGAAATGCACCTGCGGATGGCAAGGGAACGGCTGGAAGGGAAATATCAGGTCGCGGTCGAGATACGCCCACCCT
CCATTCCCTATCGCGAGACGATCCGCAAGGCCGTCACGCAACGCGGCCGTCATAAGAAGCAGTCTGGCGGCCACGGACAG
TTTGGAGACGTTGTTCTCGACATCAAGCCCCTGCCCCGCGGCAGCGGTTTTGAATTTACCGAGACCATCACCGGAGGCGT
GGTCCCCAAGCAATATATTCCATCGGTTGAAACAGGAGTGCGCGATTCCCTCAAGGCGGGGCCGCTGGGTTTTCCCGTGG
TCGACATCTCGGTCAATCTGGCGGACGGCTCCTATCACACCGTCGATTCTTCCGACATGGCGTTCCAGCAGGCAGCCCGC
CTCGCCATGAAGGAGGGTCTTGCGGCCGCTGGCCCGGTTCTTCTCGAGCCGATTCTTAAGGTGGAGGTTCACACGCCTTC
CGATGCCACGGCGCGCGCGACGGCGATCCTTTCGCAGCGGCGCGGTCAGATTCTGGGCTTTAACACACGCCCAGGCTGGC
CGGGATGGGACGTGGTCGAAGCCATGGTGCCGGAAGCGGAAATGGGAAACCTCATCATCGAGCTCCGCTCGGCCACGGCG
GGCGTGGCAGGATACCGTGCTGCTTTCGACCACATGGCGGAGCTGACGGGAAGGCTGGCCGACGATGCGCTGAACAGCCG
GGGTAAGGCCGCCTGA

Upstream 100 bases:

>100_bases
ACGATGAGTTGCGCAGCCTCGACATTAGTCGGTGCTGCGGTGCGACGGCTGTTGGGGGCCGGCCGCCGCTCATGGGAGGA
CGCTTGAAAGGAGTCGGCCT

Downstream 100 bases:

>100_bases
ACAAGCCTGGAAACCTGAATGGTTCGTGTCTCACGACCAGAACTCTGGCGGAGAGAGCGGGCGCCAACTGATAGCTGAAT
GAAGAAAAAAAAGAGGCCGG

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 671; Mature: 670

Protein sequence:

>671_residues
MGNRAGDRFKGPKCIAILGPLASGKTTLFEAILRRTGAISGQGGPSADTRTHTMSVEASFATTSFMGESITFVDCPGSIE
FAEEAGPVLAAADAAVVVIDAEDHKLPMLQLILRRLDDIGIPRMLFLNKLDKSAIGVRETLKALQPASSPPLLLRHIPLR
KNGLLIGSIDLALERAYIYREHAESEIAPIPDDEKAREIEARFSMLETLADHDDQLMEQLLEEIEPPRDAIFDDLAADVR
EGTVTPVLIGSAEKGNGILRLLKAIRHDVADVTETRKRLGHSNGDGSATLQVMKTIHTGHGGKISVCRILSGTINDGTEL
PDAGRISGIYSLIGRDQTKLASAGEGDTVALGKLDGATTGDTLSTSKGAARQLAKPTPPHPVFVVAVSPRDRKDEVKLSA
ALQKLQEEDPSLLLQQSQDTAETILGGQGEMHLRMARERLEGKYQVAVEIRPPSIPYRETIRKAVTQRGRHKKQSGGHGQ
FGDVVLDIKPLPRGSGFEFTETITGGVVPKQYIPSVETGVRDSLKAGPLGFPVVDISVNLADGSYHTVDSSDMAFQQAAR
LAMKEGLAAAGPVLLEPILKVEVHTPSDATARATAILSQRRGQILGFNTRPGWPGWDVVEAMVPEAEMGNLIIELRSATA
GVAGYRAAFDHMAELTGRLADDALNSRGKAA

Sequences:

>Translated_671_residues
MGNRAGDRFKGPKCIAILGPLASGKTTLFEAILRRTGAISGQGGPSADTRTHTMSVEASFATTSFMGESITFVDCPGSIE
FAEEAGPVLAAADAAVVVIDAEDHKLPMLQLILRRLDDIGIPRMLFLNKLDKSAIGVRETLKALQPASSPPLLLRHIPLR
KNGLLIGSIDLALERAYIYREHAESEIAPIPDDEKAREIEARFSMLETLADHDDQLMEQLLEEIEPPRDAIFDDLAADVR
EGTVTPVLIGSAEKGNGILRLLKAIRHDVADVTETRKRLGHSNGDGSATLQVMKTIHTGHGGKISVCRILSGTINDGTEL
PDAGRISGIYSLIGRDQTKLASAGEGDTVALGKLDGATTGDTLSTSKGAARQLAKPTPPHPVFVVAVSPRDRKDEVKLSA
ALQKLQEEDPSLLLQQSQDTAETILGGQGEMHLRMARERLEGKYQVAVEIRPPSIPYRETIRKAVTQRGRHKKQSGGHGQ
FGDVVLDIKPLPRGSGFEFTETITGGVVPKQYIPSVETGVRDSLKAGPLGFPVVDISVNLADGSYHTVDSSDMAFQQAAR
LAMKEGLAAAGPVLLEPILKVEVHTPSDATARATAILSQRRGQILGFNTRPGWPGWDVVEAMVPEAEMGNLIIELRSATA
GVAGYRAAFDHMAELTGRLADDALNSRGKAA
>Mature_670_residues
GNRAGDRFKGPKCIAILGPLASGKTTLFEAILRRTGAISGQGGPSADTRTHTMSVEASFATTSFMGESITFVDCPGSIEF
AEEAGPVLAAADAAVVVIDAEDHKLPMLQLILRRLDDIGIPRMLFLNKLDKSAIGVRETLKALQPASSPPLLLRHIPLRK
NGLLIGSIDLALERAYIYREHAESEIAPIPDDEKAREIEARFSMLETLADHDDQLMEQLLEEIEPPRDAIFDDLAADVRE
GTVTPVLIGSAEKGNGILRLLKAIRHDVADVTETRKRLGHSNGDGSATLQVMKTIHTGHGGKISVCRILSGTINDGTELP
DAGRISGIYSLIGRDQTKLASAGEGDTVALGKLDGATTGDTLSTSKGAARQLAKPTPPHPVFVVAVSPRDRKDEVKLSAA
LQKLQEEDPSLLLQQSQDTAETILGGQGEMHLRMARERLEGKYQVAVEIRPPSIPYRETIRKAVTQRGRHKKQSGGHGQF
GDVVLDIKPLPRGSGFEFTETITGGVVPKQYIPSVETGVRDSLKAGPLGFPVVDISVNLADGSYHTVDSSDMAFQQAARL
AMKEGLAAAGPVLLEPILKVEVHTPSDATARATAILSQRRGQILGFNTRPGWPGWDVVEAMVPEAEMGNLIIELRSATAG
VAGYRAAFDHMAELTGRLADDALNSRGKAA

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=697, Percent_Identity=28.8378766140603, Blast_Score=252, Evalue=7e-67,
Organism=Homo sapiens, GI19923640, Length=714, Percent_Identity=25.7703081232493, Blast_Score=198, Evalue=1e-50,
Organism=Homo sapiens, GI25306287, Length=296, Percent_Identity=29.0540540540541, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI25306283, Length=380, Percent_Identity=25.2631578947368, Blast_Score=101, Evalue=2e-21,
Organism=Escherichia coli, GI1789738, Length=706, Percent_Identity=32.2946175637394, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1790835, Length=468, Percent_Identity=22.008547008547, Blast_Score=63, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17533571, Length=682, Percent_Identity=27.4193548387097, Blast_Score=246, Evalue=3e-65,
Organism=Caenorhabditis elegans, GI17556745, Length=701, Percent_Identity=20.8273894436519, Blast_Score=120, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323098, Length=677, Percent_Identity=27.6218611521418, Blast_Score=239, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6322359, Length=520, Percent_Identity=28.0769230769231, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6324707, Length=431, Percent_Identity=25.2900232018561, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6320593, Length=431, Percent_Identity=25.2900232018561, Blast_Score=99, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24582462, Length=666, Percent_Identity=29.7297297297297, Blast_Score=257, Evalue=2e-68,
Organism=Drosophila melanogaster, GI221458488, Length=709, Percent_Identity=24.4005641748942, Blast_Score=154, Evalue=1e-37,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 71834; Mature: 71703

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRAGDRFKGPKCIAILGPLASGKTTLFEAILRRTGAISGQGGPSADTRTHTMSVEASF
CCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEHH
ATTSFMGESITFVDCPGSIEFAEEAGPVLAAADAAVVVIDAEDHKLPMLQLILRRLDDIG
HHHHHCCCCEEEEECCCCCEEHHHCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCC
IPRMLFLNKLDKSAIGVRETLKALQPASSPPLLLRHIPLRKNGLLIGSIDLALERAYIYR
CCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHH
EHAESEIAPIPDDEKAREIEARFSMLETLADHDDQLMEQLLEEIEPPRDAIFDDLAADVR
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EGTVTPVLIGSAEKGNGILRLLKAIRHDVADVTETRKRLGHSNGDGSATLQVMKTIHTGH
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGKISVCRILSGTINDGTELPDAGRISGIYSLIGRDQTKLASAGEGDTVALGKLDGATTG
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCCCC
DTLSTSKGAARQLAKPTPPHPVFVVAVSPRDRKDEVKLSAALQKLQEEDPSLLLQQSQDT
CCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHH
AETILGGQGEMHLRMARERLEGKYQVAVEIRPPSIPYRETIRKAVTQRGRHKKQSGGHGQ
HHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
FGDVVLDIKPLPRGSGFEFTETITGGVVPKQYIPSVETGVRDSLKAGPLGFPVVDISVNL
CCCEEEEEEECCCCCCCCHHHHHCCCCCCHHHCCCHHHCHHHHHCCCCCCCEEEEEEEEE
ADGSYHTVDSSDMAFQQAARLAMKEGLAAAGPVLLEPILKVEVHTPSDATARATAILSQR
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHH
RGQILGFNTRPGWPGWDVVEAMVPEAEMGNLIIELRSATAGVAGYRAAFDHMAELTGRLA
CCCEEEECCCCCCCCHHHHHHHCCCHHHCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHH
DDALNSRGKAA
HHHHCCCCCCC
>Mature Secondary Structure 
GNRAGDRFKGPKCIAILGPLASGKTTLFEAILRRTGAISGQGGPSADTRTHTMSVEASF
CCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEHH
ATTSFMGESITFVDCPGSIEFAEEAGPVLAAADAAVVVIDAEDHKLPMLQLILRRLDDIG
HHHHHCCCCEEEEECCCCCEEHHHCCCEEEECCEEEEEEECCCCCCHHHHHHHHHHHHCC
IPRMLFLNKLDKSAIGVRETLKALQPASSPPLLLRHIPLRKNGLLIGSIDLALERAYIYR
CCHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHH
EHAESEIAPIPDDEKAREIEARFSMLETLADHDDQLMEQLLEEIEPPRDAIFDDLAADVR
HHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHH
EGTVTPVLIGSAEKGNGILRLLKAIRHDVADVTETRKRLGHSNGDGSATLQVMKTIHTGH
CCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCC
GGKISVCRILSGTINDGTELPDAGRISGIYSLIGRDQTKLASAGEGDTVALGKLDGATTG
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHCCCCCCEEEEECCCCCCCC
DTLSTSKGAARQLAKPTPPHPVFVVAVSPRDRKDEVKLSAALQKLQEEDPSLLLQQSQDT
CCCCCCCHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCHH
AETILGGQGEMHLRMARERLEGKYQVAVEIRPPSIPYRETIRKAVTQRGRHKKQSGGHGQ
HHHHHCCCCCHHHHHHHHHCCCEEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
FGDVVLDIKPLPRGSGFEFTETITGGVVPKQYIPSVETGVRDSLKAGPLGFPVVDISVNL
CCCEEEEEEECCCCCCCCHHHHHCCCCCCHHHCCCHHHCHHHHHCCCCCCCEEEEEEEEE
ADGSYHTVDSSDMAFQQAARLAMKEGLAAAGPVLLEPILKVEVHTPSDATARATAILSQR
CCCCEEECCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHEEEEECCCCCHHHHHHHHHHH
RGQILGFNTRPGWPGWDVVEAMVPEAEMGNLIIELRSATAGVAGYRAAFDHMAELTGRLA
CCCEEEECCCCCCCCHHHHHHHCCCHHHCCEEEEEECHHCCHHHHHHHHHHHHHHHHHHH
DDALNSRGKAA
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]