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The map label for this gene is appC [H]

Identifier: 110634410

GI number: 110634410

Start: 2211389

End: 2212546

Strand: Reverse

Name: appC [H]

Synonym: Meso_2060

Alternate gene names: 110634410

Gene position: 2212546-2211389 (Counterclockwise)

Preceding gene: 110634411

Following gene: 110634409

Centisome position: 50.14

GC content: 61.66

Gene sequence:

>1158_bases
ATGCAATATGAGACGATCGGCGCTTTCGGCATTCTCATCGGCATCGTCGTGCGATTCTGGCCGGTCTGGATCGCGCTCGC
GATCGTCGTCACCTTCAGCCTTACGTTCAGAAAGCGCCTCGGCCTTTACGGCCAGCTTTACGGCAATCGGGCCGGTATCG
CAGGCTTGATCCTTTGCCTGTTCTGGCTGTTCACGGCCGTTTTCGCCTCCATGATCGCGCCGTTCGAGCCGCTGCAGCAG
ATCGCGATCATGAAGGATGCGCCGCCGGGCGCCCTCGATCCGGATACGGGCGCGGTGTTCCTTCTCGGGGGGGACCGGCT
GGCGCGCGACGTCTTCTCGCGCATGGTCTTCGGCAGCCAGATCGTTCTCGTCATCGCGCCCGCCGCCACACTCTTTGCAC
TGATCGTCGGGACAATGCTGGGTCTGCCGGCAGGCTATCACGGCGGCAGGATCGACAATATCCTGTCGTTCCTCGCCAAT
CTGGTGCTCGCCTTTCCGGTCATCCTGCTTTTTTATCTGCTGGTGACACCCGGCGTTCGGGAAACCTCGATCCCACAATG
GCTTGCGGGCTTTTTCCTCATCTTTCCGGTGATCTTCTTCTGCACGCTATTCTGGACGCGCTATTCAAGCCGGCCGGGGC
TTCTTGCACCGCTTCTCGCGATCACGTTTCTTCTCGGCGGCTGGCTTTATGCCGGGCTTGTGTTCCGTGCCGATCCGTTG
GGGCTGATTTCACTCGCGCCCAACGAACTCAATATCTTCGTGGCGGTGGTGTTTGCCTCGAGCCCCGGCGTGTTTCGGAT
CGTGCGCGGCCTCACCATGGAGATCAGGACGCGTGACTATGTGGCGGCGGCCCAAACCCGCGGCGAGCGGCCATGGTACA
TCATGCTATGGGAGATACTGCCGAATGCGCGCGGGCCGCTCATTGTGGATGCATGCCTGCGCGTTGGCTACACGACCATT
CTTCTGGGCACTCTCGGCTATTTCGGCCTCGGCCTCACGCCGGAAAGCCCGGATTGGGGGACGGCGATAAAGGAATCAAG
CCGGCTCCTGCGTGCCCATGTCCACCCGGCGCTGCCGCCGGTCGTGGCCCTGATGTCCTTCGTGCTGGGCCTCAATCTGC
TCGCTGACGCGTTGCGCGAGCAGGCATTGAAGGATTGA

Upstream 100 bases:

>100_bases
TTCGCTCATTTCCGTGTTCGTCGTGCTTTCGACACAGCTTGTTTCCGATCTTGGATACGCGCTGCTCAATCCGCGCATCC
GGGTACAGTAGAGAACGCCG

Downstream 100 bases:

>100_bases
GAGCGATGAACGGCGCAGCGCCTATCCTGGAAATCGAAAACCTCTCCATCTCCTTCTTCACGCAGGCAGGGGAGGTGCCG
GTGGTCAAGGATTTTTCCAG

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MQYETIGAFGILIGIVVRFWPVWIALAIVVTFSLTFRKRLGLYGQLYGNRAGIAGLILCLFWLFTAVFASMIAPFEPLQQ
IAIMKDAPPGALDPDTGAVFLLGGDRLARDVFSRMVFGSQIVLVIAPAATLFALIVGTMLGLPAGYHGGRIDNILSFLAN
LVLAFPVILLFYLLVTPGVRETSIPQWLAGFFLIFPVIFFCTLFWTRYSSRPGLLAPLLAITFLLGGWLYAGLVFRADPL
GLISLAPNELNIFVAVVFASSPGVFRIVRGLTMEIRTRDYVAAAQTRGERPWYIMLWEILPNARGPLIVDACLRVGYTTI
LLGTLGYFGLGLTPESPDWGTAIKESSRLLRAHVHPALPPVVALMSFVLGLNLLADALREQALKD

Sequences:

>Translated_385_residues
MQYETIGAFGILIGIVVRFWPVWIALAIVVTFSLTFRKRLGLYGQLYGNRAGIAGLILCLFWLFTAVFASMIAPFEPLQQ
IAIMKDAPPGALDPDTGAVFLLGGDRLARDVFSRMVFGSQIVLVIAPAATLFALIVGTMLGLPAGYHGGRIDNILSFLAN
LVLAFPVILLFYLLVTPGVRETSIPQWLAGFFLIFPVIFFCTLFWTRYSSRPGLLAPLLAITFLLGGWLYAGLVFRADPL
GLISLAPNELNIFVAVVFASSPGVFRIVRGLTMEIRTRDYVAAAQTRGERPWYIMLWEILPNARGPLIVDACLRVGYTTI
LLGTLGYFGLGLTPESPDWGTAIKESSRLLRAHVHPALPPVVALMSFVLGLNLLADALREQALKD
>Mature_385_residues
MQYETIGAFGILIGIVVRFWPVWIALAIVVTFSLTFRKRLGLYGQLYGNRAGIAGLILCLFWLFTAVFASMIAPFEPLQQ
IAIMKDAPPGALDPDTGAVFLLGGDRLARDVFSRMVFGSQIVLVIAPAATLFALIVGTMLGLPAGYHGGRIDNILSFLAN
LVLAFPVILLFYLLVTPGVRETSIPQWLAGFFLIFPVIFFCTLFWTRYSSRPGLLAPLLAITFLLGGWLYAGLVFRADPL
GLISLAPNELNIFVAVVFASSPGVFRIVRGLTMEIRTRDYVAAAQTRGERPWYIMLWEILPNARGPLIVDACLRVGYTTI
LLGTLGYFGLGLTPESPDWGTAIKESSRLLRAHVHPALPPVVALMSFVLGLNLLADALREQALKD

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787760, Length=138, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787054, Length=130, Percent_Identity=31.5384615384615, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1789964, Length=134, Percent_Identity=30.5970149253731, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787498, Length=333, Percent_Identity=25.5255255255255, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42133; Mature: 42133

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYETIGAFGILIGIVVRFWPVWIALAIVVTFSLTFRKRLGLYGQLYGNRAGIAGLILCL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH
FWLFTAVFASMIAPFEPLQQIAIMKDAPPGALDPDTGAVFLLGGDRLARDVFSRMVFGSQ
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCC
IVLVIAPAATLFALIVGTMLGLPAGYHGGRIDNILSFLANLVLAFPVILLFYLLVTPGVR
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ETSIPQWLAGFFLIFPVIFFCTLFWTRYSSRPGLLAPLLAITFLLGGWLYAGLVFRADPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLISLAPNELNIFVAVVFASSPGVFRIVRGLTMEIRTRDYVAAAQTRGERPWYIMLWEIL
CEEEECCCCCEEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEHHHC
PNARGPLIVDACLRVGYTTILLGTLGYFGLGLTPESPDWGTAIKESSRLLRAHVHPALPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
VVALMSFVLGLNLLADALREQALKD
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MQYETIGAFGILIGIVVRFWPVWIALAIVVTFSLTFRKRLGLYGQLYGNRAGIAGLILCL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHH
FWLFTAVFASMIAPFEPLQQIAIMKDAPPGALDPDTGAVFLLGGDRLARDVFSRMVFGSQ
HHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHCCC
IVLVIAPAATLFALIVGTMLGLPAGYHGGRIDNILSFLANLVLAFPVILLFYLLVTPGVR
EEEEEECHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
ETSIPQWLAGFFLIFPVIFFCTLFWTRYSSRPGLLAPLLAITFLLGGWLYAGLVFRADPL
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
GLISLAPNELNIFVAVVFASSPGVFRIVRGLTMEIRTRDYVAAAQTRGERPWYIMLWEIL
CEEEECCCCCEEEEEEEEECCCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCCEEEEHHHC
PNARGPLIVDACLRVGYTTILLGTLGYFGLGLTPESPDWGTAIKESSRLLRAHVHPALPP
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCH
VVALMSFVLGLNLLADALREQALKD
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]