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The map label for this gene is dinF [H]

Identifier: 110634190

GI number: 110634190

Start: 1976101

End: 1977477

Strand: Direct

Name: dinF [H]

Synonym: Meso_1840

Alternate gene names: 110634190

Gene position: 1976101-1977477 (Clockwise)

Preceding gene: 110634179

Following gene: 110634191

Centisome position: 44.78

GC content: 60.78

Gene sequence:

>1377_bases
ATGACAATTGACCAGCCACGGCTTGACCAGGAATCTTCCCCTGGTTCGCAGATGCCTGCCACCACCGTTACCCATGGCCA
GGTGCTGAAGATTGCGTTGCCAATCACCCTGGCATCGATATCGACACCCCTGGTCGGCATCGTTGACACTGCAGTTGTCG
GGCAGTTGGGGAACGAAGCCCTGATCGGCGGCATCGCTGCCGCCAACGTGATCATCAACCTCGTCTTCTTCACCTTCAAC
TTCCTGCGTTCCTCCACCACTGCCATGGTTTCGCAAGCGTTCGGGGCGGGACACGGGATAGAGATGCTCGCGCATGCGCT
CCGCGCCATATGCTTGGCTTTCGCGGCAGGCCTCATCGCAGTGGCGCTACAGTGGCCGATTGCCTATGCCGGCTTTTCCC
TGCTCGGCGTCGGCGAGGATGTAAGGGCAGCCGGAATGGTCTATTTCGGCATCCGCGTCTGGTCAGCGCCGCTGCTGCTC
GTCAATTATGCGCTGGTGGGCTGGCTCTTCGGCCAGGGCTCTTTCCTGCCGGGCCTTGCCCTCCAGGCAGTGCTCAACCT
CGTCAACGCAATACTCAGTATCGCTTTCGTCCTCCATTTCGATTGGGGTGTTGCCGGCGCGGCGCTGGCGACGGTGGCCG
CAGAGACGGCCACCGCTCTCGCCGGCGGCATTCTGATAGCGCGCGCTCTTCATGGAAAGGCACGGGCAGTGCTTTCAGCC
CTGCCGGACATGCGCCAACTGAAGCGGATACTCAGCATCAATGCAGACATTCTTCTGCGATCCATGATTCGCTTTTTCAG
CATCGCTCTCTTCACGCGGGAGAGTGCCGCTTTTGGCACGGCGATGCTCGCAGCCAACGTCGTGCTGATGAACCTCTTCT
ATTTTTCCGGCGCGATGATCCAGGGGCTTGCCGTCGCCGCCCAGCACCTTGCCGGAAGGGCGGTGGGCGGGTGTGACCGC
GTCATGTTCGAAACATCGGTAAACCTCTCCGTCTTCTGGAGCGTTGCGACGGGCTTTGCTGTGGCGGCGGTCTATCTCAT
CGTTCAAGACCCGATCATCGCGCTCATGACGGCAAGTCCTGATGTACGTGCGCTCGCTCACGCCTATTTTCACTGGGCGC
TACTGACTGCCCCGCTCGGCAGTCTTGCCTTCGTCATGGATGGCGTCTTCATAGGTGCGACCTGGGCGCGCGACATCCGC
AACATGATGCTCGTCGCTTCGGCCTGCTACCTGCTGCTCATCTTCACCCTTATCCCCTGGCTCGGCAACGATGGACTATG
GATCGCCTTCCTCGCGTTCCTCGCCGTGCGCGGTTTCACGCTTCGTTGGCGCATGAACCGGCTGATGTCACGCACCTTTC
CGCTCCCCTCCCGATAG

Upstream 100 bases:

>100_bases
TGGGCAGAACGGCAGCGAGTGCGACTGATCGTATGACCGCATCCTGCTGCGCTGGGTGCGGCAGGGTGCGCCCGTTCAAA
AGAAGCGGGAGCGCCGCCCG

Downstream 100 bases:

>100_bases
CCGTCAGCGGAAGCCCCCCGGCGGAATTTCTTTCTGTATGCAATTAAAAATATTGATTTGAATGTAGAAGTGTACTTTAC
TGAGGTGGTACCGATACCCG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTIDQPRLDQESSPGSQMPATTVTHGQVLKIALPITLASISTPLVGIVDTAVVGQLGNEALIGGIAAANVIINLVFFTFN
FLRSSTTAMVSQAFGAGHGIEMLAHALRAICLAFAAGLIAVALQWPIAYAGFSLLGVGEDVRAAGMVYFGIRVWSAPLLL
VNYALVGWLFGQGSFLPGLALQAVLNLVNAILSIAFVLHFDWGVAGAALATVAAETATALAGGILIARALHGKARAVLSA
LPDMRQLKRILSINADILLRSMIRFFSIALFTRESAAFGTAMLAANVVLMNLFYFSGAMIQGLAVAAQHLAGRAVGGCDR
VMFETSVNLSVFWSVATGFAVAAVYLIVQDPIIALMTASPDVRALAHAYFHWALLTAPLGSLAFVMDGVFIGATWARDIR
NMMLVASACYLLLIFTLIPWLGNDGLWIAFLAFLAVRGFTLRWRMNRLMSRTFPLPSR

Sequences:

>Translated_458_residues
MTIDQPRLDQESSPGSQMPATTVTHGQVLKIALPITLASISTPLVGIVDTAVVGQLGNEALIGGIAAANVIINLVFFTFN
FLRSSTTAMVSQAFGAGHGIEMLAHALRAICLAFAAGLIAVALQWPIAYAGFSLLGVGEDVRAAGMVYFGIRVWSAPLLL
VNYALVGWLFGQGSFLPGLALQAVLNLVNAILSIAFVLHFDWGVAGAALATVAAETATALAGGILIARALHGKARAVLSA
LPDMRQLKRILSINADILLRSMIRFFSIALFTRESAAFGTAMLAANVVLMNLFYFSGAMIQGLAVAAQHLAGRAVGGCDR
VMFETSVNLSVFWSVATGFAVAAVYLIVQDPIIALMTASPDVRALAHAYFHWALLTAPLGSLAFVMDGVFIGATWARDIR
NMMLVASACYLLLIFTLIPWLGNDGLWIAFLAFLAVRGFTLRWRMNRLMSRTFPLPSR
>Mature_457_residues
TIDQPRLDQESSPGSQMPATTVTHGQVLKIALPITLASISTPLVGIVDTAVVGQLGNEALIGGIAAANVIINLVFFTFNF
LRSSTTAMVSQAFGAGHGIEMLAHALRAICLAFAAGLIAVALQWPIAYAGFSLLGVGEDVRAAGMVYFGIRVWSAPLLLV
NYALVGWLFGQGSFLPGLALQAVLNLVNAILSIAFVLHFDWGVAGAALATVAAETATALAGGILIARALHGKARAVLSAL
PDMRQLKRILSINADILLRSMIRFFSIALFTRESAAFGTAMLAANVVLMNLFYFSGAMIQGLAVAAQHLAGRAVGGCDRV
MFETSVNLSVFWSVATGFAVAAVYLIVQDPIIALMTASPDVRALAHAYFHWALLTAPLGSLAFVMDGVFIGATWARDIRN
MMLVASACYLLLIFTLIPWLGNDGLWIAFLAFLAVRGFTLRWRMNRLMSRTFPLPSR

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=422, Percent_Identity=34.3601895734597, Blast_Score=177, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48743; Mature: 48612

Theoretical pI: Translated: 9.70; Mature: 9.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDQPRLDQESSPGSQMPATTVTHGQVLKIALPITLASISTPLVGIVDTAVVGQLGNEA
CCCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCHH
LIGGIAAANVIINLVFFTFNFLRSSTTAMVSQAFGAGHGIEMLAHALRAICLAFAAGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VALQWPIAYAGFSLLGVGEDVRAAGMVYFGIRVWSAPLLLVNYALVGWLFGQGSFLPGLA
HHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQAVLNLVNAILSIAFVLHFDWGVAGAALATVAAETATALAGGILIARALHGKARAVLSA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPDMRQLKRILSINADILLRSMIRFFSIALFTRESAAFGTAMLAANVVLMNLFYFSGAMI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLAVAAQHLAGRAVGGCDRVMFETSVNLSVFWSVATGFAVAAVYLIVQDPIIALMTASP
HHHHHHHHHHHCCCCCCHHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHCCHHEEEECCC
DVRALAHAYFHWALLTAPLGSLAFVMDGVFIGATWARDIRNMMLVASACYLLLIFTLIPW
HHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGNDGLWIAFLAFLAVRGFTLRWRMNRLMSRTFPLPSR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TIDQPRLDQESSPGSQMPATTVTHGQVLKIALPITLASISTPLVGIVDTAVVGQLGNEA
CCCCCCCCCCCCCCCCCCCCEECCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCHH
LIGGIAAANVIINLVFFTFNFLRSSTTAMVSQAFGAGHGIEMLAHALRAICLAFAAGLIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
VALQWPIAYAGFSLLGVGEDVRAAGMVYFGIRVWSAPLLLVNYALVGWLFGQGSFLPGLA
HHHHHHHHHHCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
LQAVLNLVNAILSIAFVLHFDWGVAGAALATVAAETATALAGGILIARALHGKARAVLSA
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPDMRQLKRILSINADILLRSMIRFFSIALFTRESAAFGTAMLAANVVLMNLFYFSGAMI
CCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QGLAVAAQHLAGRAVGGCDRVMFETSVNLSVFWSVATGFAVAAVYLIVQDPIIALMTASP
HHHHHHHHHHHCCCCCCHHHHHEEECCCCEEHHHHHHHHHHHHHHHHHHCCHHEEEECCC
DVRALAHAYFHWALLTAPLGSLAFVMDGVFIGATWARDIRNMMLVASACYLLLIFTLIPW
HHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGNDGLWIAFLAFLAVRGFTLRWRMNRLMSRTFPLPSR
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]