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The map label for this gene is mhpC [C]

Identifier: 110634082

GI number: 110634082

Start: 1851837

End: 1852592

Strand: Reverse

Name: mhpC [C]

Synonym: Meso_1731

Alternate gene names: 110634082

Gene position: 1852592-1851837 (Counterclockwise)

Preceding gene: 110634083

Following gene: 110634081

Centisome position: 41.99

GC content: 61.24

Gene sequence:

>756_bases
ATGCAGTTTTTCAGTCACGACGGTTTCGAACTCGCCTTCATCGACGAAGGCGAGGGTGACCCGATCCTTCTAATCCATGG
CTTTGCCTCCACCCATTTCGTGAATTGGGTGGCGCCTGGCTGGGTGAAAACCTTGAGGGATGCGGGCTACCGCGTCATTG
CGCTCGATAATCGCGGGCATGGCCGCTCGACCAAGAGCCACGTCCGGCAGGACTATACGCCGGATAAAATGGCGGACGAT
GCGGCGGCGCTTCTCGATCATCTGGGGATCGAGCGCGCGCATGTCATGGGTTATTCCATGGGCGCGCGCATCGCTGCCTT
CCTCGCGCTGGCCCATCCGAATCGCGTGGCGACGCTGATCCTTGGAGGGCTCGGCTTTGGCATGGTGGAAGGCGTGGGTG
AGTGGGACATCATCGCAGATGCACTGCTTGCTCAAGATCCAGAGAGCATCACCCACGCGCGCGGCCGGATGTTCCGCAAC
TTCGCGGACCAGACGAAAAGCGACAGGCAGGCGCTTGCGGCCTGCATCTCCACGTCACGGACCTTGCTTGGCGCGCATGA
AGTGGCGCGGATCCGGCAGCCGGTATTGGTGGCGGTGGGTACAAGGGATGACATAGCGGGAAGACCCGAATCTCTCGCGG
CCATGTTGCCGCAGGGCGAGGCATTCTCGATCGTCGATCGCGATCACATGCTTGCGGTGGGAGACAAGACCTTTAAGGCG
CGGGCGCTCAAATTCCTGGCCTCACACCCGCTTTGA

Upstream 100 bases:

>100_bases
ACGGCGGAAAAAACGGGTATCGCCGTAGGCGATCGTCTCCATCATCCGCTCATCGACGCGGTGGCTGGTGAAAGCTAGGC
AGCAGGCGGTAACGGGGCAG

Downstream 100 bases:

>100_bases
GAGGCGCAATTTGACAACATGCTGTTGTCGAAGCATCAGGCGCGAAGCTGCCCTCCAATGGTTGGGTGTCGGAGAAGATT
CATGATGAACAATGTTCAGC

Product: alpha/beta hydrolase fold

Products: NA

Alternate protein names: Aryl-ester hydrolase; PFE; Putative bromoperoxidase [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MQFFSHDGFELAFIDEGEGDPILLIHGFASTHFVNWVAPGWVKTLRDAGYRVIALDNRGHGRSTKSHVRQDYTPDKMADD
AAALLDHLGIERAHVMGYSMGARIAAFLALAHPNRVATLILGGLGFGMVEGVGEWDIIADALLAQDPESITHARGRMFRN
FADQTKSDRQALAACISTSRTLLGAHEVARIRQPVLVAVGTRDDIAGRPESLAAMLPQGEAFSIVDRDHMLAVGDKTFKA
RALKFLASHPL

Sequences:

>Translated_251_residues
MQFFSHDGFELAFIDEGEGDPILLIHGFASTHFVNWVAPGWVKTLRDAGYRVIALDNRGHGRSTKSHVRQDYTPDKMADD
AAALLDHLGIERAHVMGYSMGARIAAFLALAHPNRVATLILGGLGFGMVEGVGEWDIIADALLAQDPESITHARGRMFRN
FADQTKSDRQALAACISTSRTLLGAHEVARIRQPVLVAVGTRDDIAGRPESLAAMLPQGEAFSIVDRDHMLAVGDKTFKA
RALKFLASHPL
>Mature_251_residues
MQFFSHDGFELAFIDEGEGDPILLIHGFASTHFVNWVAPGWVKTLRDAGYRVIALDNRGHGRSTKSHVRQDYTPDKMADD
AAALLDHLGIERAHVMGYSMGARIAAFLALAHPNRVATLILGGLGFGMVEGVGEWDIIADALLAQDPESITHARGRMFRN
FADQTKSDRQALAACISTSRTLLGAHEVARIRQPVLVAVGTRDDIAGRPESLAAMLPQGEAFSIVDRDHMLAVGDKTFKA
RALKFLASHPL

Specific function: Bifunctional enzyme, capable of both ester hydrolysis and halogenation. Has a low bromoperoxidase activity. Acts on many phenolic esters [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27597073, Length=109, Percent_Identity=30.2752293577982, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.2 [H]

Molecular weight: Translated: 27321; Mature: 27321

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFFSHDGFELAFIDEGEGDPILLIHGFASTHFVNWVAPGWVKTLRDAGYRVIALDNRGH
CCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHCCEEEEEECCCCC
GRSTKSHVRQDYTPDKMADDAAALLDHLGIERAHVMGYSMGARIAAFLALAHPNRVATLI
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHH
LGGLGFGMVEGVGEWDIIADALLAQDPESITHARGRMFRNFADQTKSDRQALAACISTSR
HHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
TLLGAHEVARIRQPVLVAVGTRDDIAGRPESLAAMLPQGEAFSIVDRDHMLAVGDKTFKA
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEEECCCHHHH
RALKFLASHPL
HHHHHHHCCCC
>Mature Secondary Structure
MQFFSHDGFELAFIDEGEGDPILLIHGFASTHFVNWVAPGWVKTLRDAGYRVIALDNRGH
CCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHCCHHHHHHHHHCCEEEEEECCCCC
GRSTKSHVRQDYTPDKMADDAAALLDHLGIERAHVMGYSMGARIAAFLALAHPNRVATLI
CCCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEHHH
LGGLGFGMVEGVGEWDIIADALLAQDPESITHARGRMFRNFADQTKSDRQALAACISTSR
HHHHHHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHH
TLLGAHEVARIRQPVLVAVGTRDDIAGRPESLAAMLPQGEAFSIVDRDHMLAVGDKTFKA
HHHHHHHHHHHCCCEEEEECCCCCCCCCHHHHHHHCCCCCEEEEECCCCEEEECCCHHHH
RALKFLASHPL
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1368608; 7704276 [H]