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The map label for this gene is recG [H]

Identifier: 110634056

GI number: 110634056

Start: 1823252

End: 1825360

Strand: Direct

Name: recG [H]

Synonym: Meso_1704

Alternate gene names: 110634056

Gene position: 1823252-1825360 (Clockwise)

Preceding gene: 110634053

Following gene: 110634063

Centisome position: 41.32

GC content: 63.63

Gene sequence:

>2109_bases
ATGCGTCCTTCGCTTCTCGATCCTCTCTTTGCCCCTGCAACAGCGCTCGAAGGCATCGGCAGCCGCACGGCCGGGCTGAT
CGCCAATGTGGTGCCGGCAGACCTGGCGAATCGCCCCTTGCGCGTGGGCGATCTGCTTTTCGTGCTGCCGCATTCGCTGA
TCGACCGCACAAACCGGCCGGAAGTAGCCTATGCGCCACAAGGCGCGATCGTAACGCTCAGGCTCACGGTAGACCGTCAT
CAGCCGCCCCCGCGCGGCAAGAAGAACGTGCCCTACCGCGTCTTCGCCTTCGATGAGACGGGTCAGATCACGCTCACCTT
TTTCCATGCGCACCCGGCTTATCTGGAGAAGCAGTTTCCGGTGGGTAGCGAGGTGCTGGTTTCAGGGCGCATGGAATGGT
TCAACGGCCGGCCTTCCATGGTCCACCCGGACTATATCGTGCCCGCCTCGGAAGCCGCGAGCCTGCCGCCCCTCGAGCCA
GTCTATCCGCTCACTGCCGGCCTATCGCCCAAGGTGCTGCGCCGCGCTATCGCGCAGGCTGTCGCCCGCGTGCCGGATAT
GCCGGAGTGGCAGGACGAAGCGCTCAAGACACAGCTCGGATTTTCCTCCTTCCGCGCCGCGCTTGATCGCCTCCACGATC
CCAAAAATGTGGAGGATATCTCCCCAGAAAACGCACCATGGCAGCGGCTCGCCTATGACGAATTGCTGGCGAGTCAGCTT
TCACTTGCGCTTGTCCGCGCACGGACACGAAAACTCGCTGGGCGTCCGCTGAATGGCGATGGCATGCTTGCTGCAAGAAT
AAAGCACGCGCTTCCCTATTCGCTCACGCCGTCCCAGGAACGCGCCGTGGCCGATATCTTTGCCGACCTGGCCAAGGACG
AGCGCATGCTGAGGCTCCTCCAGGGCGATGTGGGCGCGGGCAAGACGGTGGTGGCGCTGCTTGCCATGGCACGCGCAGCC
GAGGCCGGCGGCCAATCCGCCCTGATGGCGCCGACGGAGCTGCTTGCCCGTCAGCATTTTGCAACCGTCGCTCCGCTCGC
CGAAAAGGCCGGCCTCAAAGCTGCGCTGCTTACCGGGCGCGAGAAGGGCCGCGAGCGCCAGGAAATTCTCGCCCGTATTG
CTTCCGGCGAGGTCTCCTTCGTGATCGGTACGCATGCGCTTTTCCAGGAGACGGTGCAGTTTCATGACCTCGTGCTGACG
ATCATCGACGAGCAGCACCGTTTCGGTGTGCATCAGCGGCTGGCGATCAACGCCAAGGGCGACGCGCCGGACATGCTGGT
GATGACCGCGACCCCTATCCCGCGCACACTGGTGCTGTCTGCCTTCGGCGATATGGATGTGTCTCGGCTGACGGAGAAGC
CGGCAGGCCGCAAGCCGATCCGCACGGTCACCATGCCGACGGACCGGCTAGACGAATTGATCGAACGCCTGCAAAACGCG
ATCGTTGAGGGCCAGAAAATCTACTGGATCTGCCCGCTTGTCGAGGAGTCGGATGCGATCGAGCTTACCTCGGCAGAGGA
CCGTTTCGCCTCGCTCAAGCATGTATTCGGGCATGCGGTCGGCCTTGTCCACGGCCGTATGGCGGCGCGGGAGAAGGATG
AGGCCATGCGCGCCTTCAAGGATGGGCAGACGCGCATCCTCGTCGGCACTACGGTGGTTGAAGTGGGCGTCGATGTGCCG
GATGCGACCATCATCGTTATCGAGCATGCCGAACGATTCGGCCTCGCCCAGCTTCATCAGCTGCGCGGCCGCGTCGGACG
CAGTGATAAGCCCTCCTCATGCGTCCTTCTCTACAAACCGCCCTTGGGCGAAGTGGCGAAACGCAGGCTTGCCATCCTGC
GTGAGACCGAGGACGGCTTCCTGATTTCGGAAGAGGATTTGAAACTGCGCGGCGAAGGCGACCTTCTGGGCACCCGCCAG
TCCGGCACGCCGGGTTTCCAGGTTGCAAGACTCGAGTTCCATGCCGAGCTTCTGGCAACCGCGCGGGACGATGCCCGCCT
TCTGCTCTCGCGCGATCCCGAGCTTGCGAGCGAGCGCGGCCGGGCGCTGCGCGTGCTCCTTTATCTGTTCGGCAAGGACG
AAGCGGTGCGGCTCCTGCGTGCAGGCTAG

Upstream 100 bases:

>100_bases
TGCCTTTCGCGATGAGAGAGGGCATATAGCGTTTCATCTGTAGAAAGTCAGCCTCTCGGAAGCATTTCATCTGCCCTCAC
CTGCCGCTAAGCTCTCGTCC

Downstream 100 bases:

>100_bases
CTTACTTGCCCAGCGAATCGCCGCTGTTCCCCGGCCGGGCGACTCGGCGTGCTTTCTGCGCTTCGTCCGCAAGCAGTTCC
ATCTTCTGCTGCTGGTATTC

Product: ATP-dependent DNA helicase RecG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 702; Mature: 702

Protein sequence:

>702_residues
MRPSLLDPLFAPATALEGIGSRTAGLIANVVPADLANRPLRVGDLLFVLPHSLIDRTNRPEVAYAPQGAIVTLRLTVDRH
QPPPRGKKNVPYRVFAFDETGQITLTFFHAHPAYLEKQFPVGSEVLVSGRMEWFNGRPSMVHPDYIVPASEAASLPPLEP
VYPLTAGLSPKVLRRAIAQAVARVPDMPEWQDEALKTQLGFSSFRAALDRLHDPKNVEDISPENAPWQRLAYDELLASQL
SLALVRARTRKLAGRPLNGDGMLAARIKHALPYSLTPSQERAVADIFADLAKDERMLRLLQGDVGAGKTVVALLAMARAA
EAGGQSALMAPTELLARQHFATVAPLAEKAGLKAALLTGREKGRERQEILARIASGEVSFVIGTHALFQETVQFHDLVLT
IIDEQHRFGVHQRLAINAKGDAPDMLVMTATPIPRTLVLSAFGDMDVSRLTEKPAGRKPIRTVTMPTDRLDELIERLQNA
IVEGQKIYWICPLVEESDAIELTSAEDRFASLKHVFGHAVGLVHGRMAAREKDEAMRAFKDGQTRILVGTTVVEVGVDVP
DATIIVIEHAERFGLAQLHQLRGRVGRSDKPSSCVLLYKPPLGEVAKRRLAILRETEDGFLISEEDLKLRGEGDLLGTRQ
SGTPGFQVARLEFHAELLATARDDARLLLSRDPELASERGRALRVLLYLFGKDEAVRLLRAG

Sequences:

>Translated_702_residues
MRPSLLDPLFAPATALEGIGSRTAGLIANVVPADLANRPLRVGDLLFVLPHSLIDRTNRPEVAYAPQGAIVTLRLTVDRH
QPPPRGKKNVPYRVFAFDETGQITLTFFHAHPAYLEKQFPVGSEVLVSGRMEWFNGRPSMVHPDYIVPASEAASLPPLEP
VYPLTAGLSPKVLRRAIAQAVARVPDMPEWQDEALKTQLGFSSFRAALDRLHDPKNVEDISPENAPWQRLAYDELLASQL
SLALVRARTRKLAGRPLNGDGMLAARIKHALPYSLTPSQERAVADIFADLAKDERMLRLLQGDVGAGKTVVALLAMARAA
EAGGQSALMAPTELLARQHFATVAPLAEKAGLKAALLTGREKGRERQEILARIASGEVSFVIGTHALFQETVQFHDLVLT
IIDEQHRFGVHQRLAINAKGDAPDMLVMTATPIPRTLVLSAFGDMDVSRLTEKPAGRKPIRTVTMPTDRLDELIERLQNA
IVEGQKIYWICPLVEESDAIELTSAEDRFASLKHVFGHAVGLVHGRMAAREKDEAMRAFKDGQTRILVGTTVVEVGVDVP
DATIIVIEHAERFGLAQLHQLRGRVGRSDKPSSCVLLYKPPLGEVAKRRLAILRETEDGFLISEEDLKLRGEGDLLGTRQ
SGTPGFQVARLEFHAELLATARDDARLLLSRDPELASERGRALRVLLYLFGKDEAVRLLRAG
>Mature_702_residues
MRPSLLDPLFAPATALEGIGSRTAGLIANVVPADLANRPLRVGDLLFVLPHSLIDRTNRPEVAYAPQGAIVTLRLTVDRH
QPPPRGKKNVPYRVFAFDETGQITLTFFHAHPAYLEKQFPVGSEVLVSGRMEWFNGRPSMVHPDYIVPASEAASLPPLEP
VYPLTAGLSPKVLRRAIAQAVARVPDMPEWQDEALKTQLGFSSFRAALDRLHDPKNVEDISPENAPWQRLAYDELLASQL
SLALVRARTRKLAGRPLNGDGMLAARIKHALPYSLTPSQERAVADIFADLAKDERMLRLLQGDVGAGKTVVALLAMARAA
EAGGQSALMAPTELLARQHFATVAPLAEKAGLKAALLTGREKGRERQEILARIASGEVSFVIGTHALFQETVQFHDLVLT
IIDEQHRFGVHQRLAINAKGDAPDMLVMTATPIPRTLVLSAFGDMDVSRLTEKPAGRKPIRTVTMPTDRLDELIERLQNA
IVEGQKIYWICPLVEESDAIELTSAEDRFASLKHVFGHAVGLVHGRMAAREKDEAMRAFKDGQTRILVGTTVVEVGVDVP
DATIIVIEHAERFGLAQLHQLRGRVGRSDKPSSCVLLYKPPLGEVAKRRLAILRETEDGFLISEEDLKLRGEGDLLGTRQ
SGTPGFQVARLEFHAELLATARDDARLLLSRDPELASERGRALRVLLYLFGKDEAVRLLRAG

Specific function: Critical role in recombination and DNA repair. Help process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3' to 5' polarity. RecG unwind branched dup

COG id: COG1200

COG function: function code LK; RecG-like helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI2367254, Length=693, Percent_Identity=41.2698412698413, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1787357, Length=472, Percent_Identity=35.1694915254237, Blast_Score=243, Evalue=4e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004609
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF01336 tRNA_anti [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 77069; Mature: 77069

Theoretical pI: Translated: 7.91; Mature: 7.91

Prosite motif: PS00435 PEROXIDASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPSLLDPLFAPATALEGIGSRTAGLIANVVPADLANRPLRVGDLLFVLPHSLIDRTNRP
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCC
EVAYAPQGAIVTLRLTVDRHQPPPRGKKNVPYRVFAFDETGQITLTFFHAHPAYLEKQFP
CEEECCCCEEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHCCC
VGSEVLVSGRMEWFNGRPSMVHPDYIVPASEAASLPPLEPVYPLTAGLSPKVLRRAIAQA
CCCHHHEECCHHHCCCCCCCCCCCEECCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VARVPDMPEWQDEALKTQLGFSSFRAALDRLHDPKNVEDISPENAPWQRLAYDELLASQL
HHHCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLALVRARTRKLAGRPLNGDGMLAARIKHALPYSLTPSQERAVADIFADLAKDERMLRLL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QGDVGAGKTVVALLAMARAAEAGGQSALMAPTELLARQHFATVAPLAEKAGLKAALLTGR
HCCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCH
EKGRERQEILARIASGEVSFVIGTHALFQETVQFHDLVLTIIDEQHRFGVHQRLAINAKG
HCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCC
DAPDMLVMTATPIPRTLVLSAFGDMDVSRLTEKPAGRKPIRTVTMPTDRLDELIERLQNA
CCCCEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
IVEGQKIYWICPLVEESDAIELTSAEDRFASLKHVFGHAVGLVHGRMAAREKDEAMRAFK
HHCCCEEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGQTRILVGTTVVEVGVDVPDATIIVIEHAERFGLAQLHQLRGRVGRSDKPSSCVLLYKP
CCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECC
PLGEVAKRRLAILRETEDGFLISEEDLKLRGEGDLLGTRQSGTPGFQVARLEFHAELLAT
CHHHHHHHHHHHHEECCCCEEEECCCCEEECCCCEEECCCCCCCCCEEEHHHHHHHHHHH
ARDDARLLLSRDPELASERGRALRVLLYLFGKDEAVRLLRAG
CCCCHHEEECCCCHHHHHCCHHEEEEHHHHCCCHHHHHCCCC
>Mature Secondary Structure
MRPSLLDPLFAPATALEGIGSRTAGLIANVVPADLANRPLRVGDLLFVLPHSLIDRTNRP
CCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHCCCCCC
EVAYAPQGAIVTLRLTVDRHQPPPRGKKNVPYRVFAFDETGQITLTFFHAHPAYLEKQFP
CEEECCCCEEEEEEEEEECCCCCCCCCCCCCEEEEEECCCCCEEEEEEECCHHHHHHCCC
VGSEVLVSGRMEWFNGRPSMVHPDYIVPASEAASLPPLEPVYPLTAGLSPKVLRRAIAQA
CCCHHHEECCHHHCCCCCCCCCCCEECCCHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VARVPDMPEWQDEALKTQLGFSSFRAALDRLHDPKNVEDISPENAPWQRLAYDELLASQL
HHHCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
SLALVRARTRKLAGRPLNGDGMLAARIKHALPYSLTPSQERAVADIFADLAKDERMLRLL
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
QGDVGAGKTVVALLAMARAAEAGGQSALMAPTELLARQHFATVAPLAEKAGLKAALLTGR
HCCCCCCHHHHHHHHHHHHHHCCCCCEECCHHHHHHHHHHHHHHHHHHHCCCCEEECCCH
EKGRERQEILARIASGEVSFVIGTHALFQETVQFHDLVLTIIDEQHRFGVHQRLAINAKG
HCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHHHHCCHHHCCCCEEEEEECCC
DAPDMLVMTATPIPRTLVLSAFGDMDVSRLTEKPAGRKPIRTVTMPTDRLDELIERLQNA
CCCCEEEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCCCEEEEECCHHHHHHHHHHHHHH
IVEGQKIYWICPLVEESDAIELTSAEDRFASLKHVFGHAVGLVHGRMAAREKDEAMRAFK
HHCCCEEEEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGQTRILVGTTVVEVGVDVPDATIIVIEHAERFGLAQLHQLRGRVGRSDKPSSCVLLYKP
CCCEEEEEEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCEEEEECC
PLGEVAKRRLAILRETEDGFLISEEDLKLRGEGDLLGTRQSGTPGFQVARLEFHAELLAT
CHHHHHHHHHHHHEECCCCEEEECCCCEEECCCCEEECCCCCCCCCEEEHHHHHHHHHHH
ARDDARLLLSRDPELASERGRALRVLLYLFGKDEAVRLLRAG
CCCCHHEEECCCCHHHHHCCHHEEEEHHHHCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]