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The map label for this gene is maiA [H]

Identifier: 110633908

GI number: 110633908

Start: 1672906

End: 1673517

Strand: Direct

Name: maiA [H]

Synonym: Meso_1555

Alternate gene names: 110633908

Gene position: 1672906-1673517 (Clockwise)

Preceding gene: 110633907

Following gene: 110633911

Centisome position: 37.91

GC content: 60.62

Gene sequence:

>612_bases
ATGAAGCTCTATGACGGCGGGAGGGCACCCAACCCGAGGCGTGTGCGCATCTTTCTTGCTGAGAAGGGAATTCAGGTTCC
AACGGTACCGGTGGATATGGCACGGCGGGAGCATCAAGGGGAGGCAATCACCCGGCTCAATCCTCTGCAACGCCTGCCGA
TCCTGGAACTAGACGACGGCACCGTGATCACGGAAAGCGTCGCGATCTGCCGCTACTTCGAGGAGCAGTCGCCTGAGCCC
GCTCTCTTCGGCCGCGATGCGCTTACCAGAGCGAGGGTGGAGATGTGGCAGCGGCGCATCGAATTCGGCCTCTTTATCCC
GGTCTCGGCGGCCTTTCGCCACCTGCACCCGGCCATGAAGGGATGGGAAGTGCCGCAGGTGCCGGCATGGGGCGAGGCGA
GCAAATCCAAGGCGACGGAATTTCTCCGTTTTCTCGATGGCGAACTCGCCGGGCGTCCTTTTATTGCCGGTGATGAATTC
AGCATCGCCGATATTACCGGTTTTGTTGCTGTTCAGTTTATGAAACCCGCCCGCATAGACGTGCCGGAGGAACTTGTGCA
TGCCAGACGCTGGTATGGAGAGATGGCCTCCCGGCCAAGCGCGGGCGCTTGA

Upstream 100 bases:

>100_bases
ATTCGCCCAACGAAACGCCGCACGACTGGCTCGGACGGCTCGTCAACTTTTTGCGGCAAGTCTCCGGAATGACGTGAGGC
GAAAGGACGGGGAGGGACAC

Downstream 100 bases:

>100_bases
ACCAAATACTTGACCAGTGAGAGGCTGCCGCCTCTATCGCAGCGCTCCCACGAATTCTTGCTGTCGCCATATTTTAGCGT
ACGTGCTGCTCGGCCGCCTG

Product: glutathione S-transferase-like

Products: NA

Alternate protein names: MAAI [H]

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MKLYDGGRAPNPRRVRIFLAEKGIQVPTVPVDMARREHQGEAITRLNPLQRLPILELDDGTVITESVAICRYFEEQSPEP
ALFGRDALTRARVEMWQRRIEFGLFIPVSAAFRHLHPAMKGWEVPQVPAWGEASKSKATEFLRFLDGELAGRPFIAGDEF
SIADITGFVAVQFMKPARIDVPEELVHARRWYGEMASRPSAGA

Sequences:

>Translated_203_residues
MKLYDGGRAPNPRRVRIFLAEKGIQVPTVPVDMARREHQGEAITRLNPLQRLPILELDDGTVITESVAICRYFEEQSPEP
ALFGRDALTRARVEMWQRRIEFGLFIPVSAAFRHLHPAMKGWEVPQVPAWGEASKSKATEFLRFLDGELAGRPFIAGDEF
SIADITGFVAVQFMKPARIDVPEELVHARRWYGEMASRPSAGA
>Mature_203_residues
MKLYDGGRAPNPRRVRIFLAEKGIQVPTVPVDMARREHQGEAITRLNPLQRLPILELDDGTVITESVAICRYFEEQSPEP
ALFGRDALTRARVEMWQRRIEFGLFIPVSAAFRHLHPAMKGWEVPQVPAWGEASKSKATEFLRFLDGELAGRPFIAGDEF
SIADITGFVAVQFMKPARIDVPEELVHARRWYGEMASRPSAGA

Specific function: Forms An Equimolar Complex With The RNA Polymerase Holoenzyme (Rnap) But Not With The Core Enzyme. It Is Synthesized Predominantly When Cells Are Exposed To Amino Acid Starvation, At Which Time It Accounts For Over 50% Of The Total Protein Synthesized. It

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6322968, Length=203, Percent_Identity=37.4384236453202, Blast_Score=131, Evalue=1e-31,
Organism=Drosophila melanogaster, GI221378141, Length=196, Percent_Identity=26.0204081632653, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI62472445, Length=196, Percent_Identity=26.0204081632653, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1982 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR005955
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: =5.2.1.2 [H]

Molecular weight: Translated: 22884; Mature: 22884

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLYDGGRAPNPRRVRIFLAEKGIQVPTVPVDMARREHQGEAITRLNPLQRLPILELDDG
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHCCEEECCCC
TVITESVAICRYFEEQSPEPALFGRDALTRARVEMWQRRIEFGLFIPVSAAFRHLHPAMK
CCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHC
GWEVPQVPAWGEASKSKATEFLRFLDGELAGRPFIAGDEFSIADITGFVAVQFMKPARID
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VPEELVHARRWYGEMASRPSAGA
CHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKLYDGGRAPNPRRVRIFLAEKGIQVPTVPVDMARREHQGEAITRLNPLQRLPILELDDG
CCCCCCCCCCCCCEEEEEEECCCCCCCCCCHHHHHHHHCCCHHHHCCHHHHCCEEECCCC
TVITESVAICRYFEEQSPEPALFGRDALTRARVEMWQRRIEFGLFIPVSAAFRHLHPAMK
CCHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHHHHCEEEEHHHHHHHHHHHHC
GWEVPQVPAWGEASKSKATEFLRFLDGELAGRPFIAGDEFSIADITGFVAVQFMKPARID
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCC
VPEELVHARRWYGEMASRPSAGA
CHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]