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The map label for this gene is glcK [H]

Identifier: 110633860

GI number: 110633860

Start: 1605376

End: 1606557

Strand: Direct

Name: glcK [H]

Synonym: Meso_1507

Alternate gene names: 110633860

Gene position: 1605376-1606557 (Clockwise)

Preceding gene: 110633856

Following gene: 110633861

Centisome position: 36.38

GC content: 64.3

Gene sequence:

>1182_bases
ATGAATTTCACCTCGCAGAACTTCTCCTCGCGGAAACAGATCCAGAGTGCGGTCATCCTCGCCGTGATGGACAATGAACA
GGTGTCGCGTGCAGAGCTTGCCCGACTCTCGGGCTTATCCAAGCAGACGATGTCGGACGTGTTCCGTGATCTTGAGGAAG
ATGGCTGGATTGAAGTCGTCGGACGAACGTCCGGCACTGTCGGCCGCAGCGCGGCCGTTTATGAACTGTCGCCGAACCGG
GCACTGCTGTTCGGCGCCGATGTCGGTGGCACCAAGATTCACGCCGCGCTTGCGGACGCGAATGGCAGCGTGCTTGCCGA
AATGGAAGAGCCGACGACACAGGCGGGCGCGGAAGCGTTTGGCGCGCAGATCCTCGAGTGCTGCCGGGCGCTGGCGGCAC
AGGCGGGCCAGCCTGTGGAGCGCATTGCGGCCGGCAGCGTCGGAATTCCGGGTGCATTCGACCCGGCCCGACGGGCACTG
TTCATGGTGCCCAATATCGCCGGAATGAACGGCTATGCGATCGAGGACGATCTTCAGCGGCGGCTCGGATTTCCGGTACG
CGTCGACAACGACGTCAACATGGCTGCGAAAGGCGAAATGTGGCGTGGGGAAGGGCGAAACATCCCCTGTTTTGTGTTCA
TTGCGCTCGGCACCGGCATCGGCATGGGCATCATCAATGAAGGCCGCGTGCTTTCCGGGTCACGCGGTGCTGCCGGTGAA
ATCTCCACGCTGCCAATTGGCGGCGACCCGTTCGACGCACGCAACTTCCATGCGGGGACGCTGGAGCGCAGCGTCGGCAG
CATCGCCATTCGCGATCGCTATGAGGGCGCTGGCGGCGCCGCGGGGCTGACCGTCCGCGACATTTTTGATGCCATTGGCA
GCGGCGACCAGATCGCCAGCGCGACACTCACCGAAGTGGCGCGCCAGATTGCCGTCGGCATCGTGGCGATCTGCGCCATT
CTCGACCCGCAGCGGATCGTCATGGGCGGCAGCATCGGCGCACGCGAGGAACTGGTCGAGCGCGTCCGGCATTTCATTCC
GCTCTGCACGCCGAGACCGCCGGAATGCGTCGTCAGCACGCTGGGCCGTCGCGCTGGTCTGCTGGGTACGATCAGCCAGA
GCCGCGACCTGCTGCGCGCGATGCTGCTGACCACGGAACCGTCGAAAGTGGGGCGGCCATGA

Upstream 100 bases:

>100_bases
GCAAAAATCTTGAGATCATCACACTCACGAGCAAAACACGATTGACGAATCGCGACGAACAGATAGTTTGTCCAGTAAAC
GGACTAATTTTTTGGCTGAC

Downstream 100 bases:

>100_bases
CGGCGCAATTGCTAGCCAAGGCTGAAAATACCAGAGCGGTGGAGATCATCCGCTTCAATACCGCCGCGCAGGCCGAACGA
GCAGCGGCAGCGGTGCTGCG

Product: ROK domain-containing protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNFTSQNFSSRKQIQSAVILAVMDNEQVSRAELARLSGLSKQTMSDVFRDLEEDGWIEVVGRTSGTVGRSAAVYELSPNR
ALLFGADVGGTKIHAALADANGSVLAEMEEPTTQAGAEAFGAQILECCRALAAQAGQPVERIAAGSVGIPGAFDPARRAL
FMVPNIAGMNGYAIEDDLQRRLGFPVRVDNDVNMAAKGEMWRGEGRNIPCFVFIALGTGIGMGIINEGRVLSGSRGAAGE
ISTLPIGGDPFDARNFHAGTLERSVGSIAIRDRYEGAGGAAGLTVRDIFDAIGSGDQIASATLTEVARQIAVGIVAICAI
LDPQRIVMGGSIGAREELVERVRHFIPLCTPRPPECVVSTLGRRAGLLGTISQSRDLLRAMLLTTEPSKVGRP

Sequences:

>Translated_393_residues
MNFTSQNFSSRKQIQSAVILAVMDNEQVSRAELARLSGLSKQTMSDVFRDLEEDGWIEVVGRTSGTVGRSAAVYELSPNR
ALLFGADVGGTKIHAALADANGSVLAEMEEPTTQAGAEAFGAQILECCRALAAQAGQPVERIAAGSVGIPGAFDPARRAL
FMVPNIAGMNGYAIEDDLQRRLGFPVRVDNDVNMAAKGEMWRGEGRNIPCFVFIALGTGIGMGIINEGRVLSGSRGAAGE
ISTLPIGGDPFDARNFHAGTLERSVGSIAIRDRYEGAGGAAGLTVRDIFDAIGSGDQIASATLTEVARQIAVGIVAICAI
LDPQRIVMGGSIGAREELVERVRHFIPLCTPRPPECVVSTLGRRAGLLGTISQSRDLLRAMLLTTEPSKVGRP
>Mature_393_residues
MNFTSQNFSSRKQIQSAVILAVMDNEQVSRAELARLSGLSKQTMSDVFRDLEEDGWIEVVGRTSGTVGRSAAVYELSPNR
ALLFGADVGGTKIHAALADANGSVLAEMEEPTTQAGAEAFGAQILECCRALAAQAGQPVERIAAGSVGIPGAFDPARRAL
FMVPNIAGMNGYAIEDDLQRRLGFPVRVDNDVNMAAKGEMWRGEGRNIPCFVFIALGTGIGMGIINEGRVLSGSRGAAGE
ISTLPIGGDPFDARNFHAGTLERSVGSIAIRDRYEGAGGAAGLTVRDIFDAIGSGDQIASATLTEVARQIAVGIVAICAI
LDPQRIVMGGSIGAREELVERVRHFIPLCTPRPPECVVSTLGRRAGLLGTISQSRDLLRAMLLTTEPSKVGRP

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Escherichia coli, GI1786891, Length=339, Percent_Identity=25.6637168141593, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787363, Length=281, Percent_Identity=27.0462633451957, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790522, Length=274, Percent_Identity=26.6423357664234, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87081733, Length=275, Percent_Identity=27.2727272727273, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787878, Length=316, Percent_Identity=20.8860759493671, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 41420; Mature: 41420

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFTSQNFSSRKQIQSAVILAVMDNEQVSRAELARLSGLSKQTMSDVFRDLEEDGWIEVV
CCCCCCCHHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEE
GRTSGTVGRSAAVYELSPNRALLFGADVGGTKIHAALADANGSVLAEMEEPTTQAGAEAF
ECCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHH
GAQILECCRALAAQAGQPVERIAAGSVGIPGAFDPARRALFMVPNIAGMNGYAIEDDLQR
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHEEEECCCCCCCCCCEEHHHHHH
RLGFPVRVDNDVNMAAKGEMWRGEGRNIPCFVFIALGTGIGMGIINEGRVLSGSRGAAGE
HCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCEEECCCCCCCCC
ISTLPIGGDPFDARNFHAGTLERSVGSIAIRDRYEGAGGAAGLTVRDIFDAIGSGDQIAS
EEEECCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHH
ATLTEVARQIAVGIVAICAILDPQRIVMGGSIGAREELVERVRHFIPLCTPRPPECVVST
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
LGRRAGLLGTISQSRDLLRAMLLTTEPSKVGRP
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure
MNFTSQNFSSRKQIQSAVILAVMDNEQVSRAELARLSGLSKQTMSDVFRDLEEDGWIEVV
CCCCCCCHHHHHHHHHEEEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEE
GRTSGTVGRSAAVYELSPNRALLFGADVGGTKIHAALADANGSVLAEMEEPTTQAGAEAF
ECCCCCCCCCEEEEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCHHHHHHHH
GAQILECCRALAAQAGQPVERIAAGSVGIPGAFDPARRALFMVPNIAGMNGYAIEDDLQR
HHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHHEEEECCCCCCCCCCEEHHHHHH
RLGFPVRVDNDVNMAAKGEMWRGEGRNIPCFVFIALGTGIGMGIINEGRVLSGSRGAAGE
HCCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCEECCCEEECCCCCCCCC
ISTLPIGGDPFDARNFHAGTLERSVGSIAIRDRYEGAGGAAGLTVRDIFDAIGSGDQIAS
EEEECCCCCCCCCCCCCCHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHH
ATLTEVARQIAVGIVAICAILDPQRIVMGGSIGAREELVERVRHFIPLCTPRPPECVVST
HHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHH
LGRRAGLLGTISQSRDLLRAMLLTTEPSKVGRP
HHHHCCCHHHHHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]