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The map label for this gene is mmsR [H]

Identifier: 110633854

GI number: 110633854

Start: 1598731

End: 1599774

Strand: Reverse

Name: mmsR [H]

Synonym: Meso_1501

Alternate gene names: 110633854

Gene position: 1599774-1598731 (Counterclockwise)

Preceding gene: 110633857

Following gene: 110633853

Centisome position: 36.26

GC content: 65.33

Gene sequence:

>1044_bases
ATGCGAGATGAAATCGGACCTGACACGGCGGCGCGCATCCAACTGCTCGTGGTGCCGGAGACGACGCCTGGCACCCTCTA
CGGGCTCTACGAGCTTTTCGATGCGGTGGGCGTGGCGTGGAAGGACATAACGGGCGAAGCGGTCAACACGCCTCGCCTCT
CCCCTCGCATTGTATCGGCCGGCGGAACTGCCTTCGCCTCGCCAATCGGCATCCCCATTGTGCCGCATGACGCACTTTCC
GCAGCCGGCCGCGCAGAGGTGGTCATCGTCCCCGACCTATCGCTGACCCAGGATCACGATCCGCGCGGACGCTGGGCGGA
GGAGGCAGCTTGGCTTCGCCGCCGCTTCGATGACGGCGCAGTCCTCTGCTCCGTCTGCACGGGCTCGGTGCTTCTTGCGG
AGGCAGGCCTGCTCGAAGGCGTGGAAGCCACTACCCACTGGGGCGTTACGCGCCTCTTCTCGCGGTACTATCCGCGCGTG
AGGCTGCATGCCGAGCGCATTCTGTCGCCAAGTGGGCCTGAGCACCGCATCGTCACCTGCGGCGGTGCGGGCTCCTGGTC
AGATCTGGCGCTCTATCTTATCGCGCGCTTCTGCGGCCCCGCCGAGGCGGTGCGCCTGGCCAAAGTCTTCGTTCTCGGAG
ACCGCAGCGAGGGACAATTGCCCTTCGCGGCCATGGGCCGCGTGCCTCCCCATAGCGATGCGGCGGTGAGCCGCTGCCAG
GAATGGCTTGCCGATCATTATTACGAGCCCAATCCGGTCGCCCGCATGGCCGCCCTTTCGGGCCTTCCAGAACGTACCTT
CAAGCGGCGTTTCAAGGCGGCCACCGGTTATTCGCCGATCGACTACGTTCAAGCGCTGCGCATCGAGGAGGCAAAGCAAA
TGCTGGAGACGACCGGCCAGCCGACCGATGCCGTCGCTCACGCGGTAGGCTATGACGACCCGGCATTCTTCCGCCGCCTC
TTCAAACGCTCGACCGGTGTCACCCCTGCTCGCTACCGCCAACGCTACCGCTTCATCGGCCTGGCAGCCAAAGACGTGGT
CTAA

Upstream 100 bases:

>100_bases
TTGTCTCCTGAATGTCGAAGACGGCGGTCTAGACGCGAATGGGACCAGCAAGAAGTGCGAGAATGGACAAGAACGAGGCA
TTCGTGCCAAATTTGCCTGC

Downstream 100 bases:

>100_bases
GACACCGCCCGGCGGATTCGATTAATTCTCTGTTGCAGCATTTCGCTGCCCCGCCAGAACAGGTGTTTGCCGATGATAAC
TCAACGCATCGAATTTCGGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MRDEIGPDTAARIQLLVVPETTPGTLYGLYELFDAVGVAWKDITGEAVNTPRLSPRIVSAGGTAFASPIGIPIVPHDALS
AAGRAEVVIVPDLSLTQDHDPRGRWAEEAAWLRRRFDDGAVLCSVCTGSVLLAEAGLLEGVEATTHWGVTRLFSRYYPRV
RLHAERILSPSGPEHRIVTCGGAGSWSDLALYLIARFCGPAEAVRLAKVFVLGDRSEGQLPFAAMGRVPPHSDAAVSRCQ
EWLADHYYEPNPVARMAALSGLPERTFKRRFKAATGYSPIDYVQALRIEEAKQMLETTGQPTDAVAHAVGYDDPAFFRRL
FKRSTGVTPARYRQRYRFIGLAAKDVV

Sequences:

>Translated_347_residues
MRDEIGPDTAARIQLLVVPETTPGTLYGLYELFDAVGVAWKDITGEAVNTPRLSPRIVSAGGTAFASPIGIPIVPHDALS
AAGRAEVVIVPDLSLTQDHDPRGRWAEEAAWLRRRFDDGAVLCSVCTGSVLLAEAGLLEGVEATTHWGVTRLFSRYYPRV
RLHAERILSPSGPEHRIVTCGGAGSWSDLALYLIARFCGPAEAVRLAKVFVLGDRSEGQLPFAAMGRVPPHSDAAVSRCQ
EWLADHYYEPNPVARMAALSGLPERTFKRRFKAATGYSPIDYVQALRIEEAKQMLETTGQPTDAVAHAVGYDDPAFFRRL
FKRSTGVTPARYRQRYRFIGLAAKDVV
>Mature_347_residues
MRDEIGPDTAARIQLLVVPETTPGTLYGLYELFDAVGVAWKDITGEAVNTPRLSPRIVSAGGTAFASPIGIPIVPHDALS
AAGRAEVVIVPDLSLTQDHDPRGRWAEEAAWLRRRFDDGAVLCSVCTGSVLLAEAGLLEGVEATTHWGVTRLFSRYYPRV
RLHAERILSPSGPEHRIVTCGGAGSWSDLALYLIARFCGPAEAVRLAKVFVLGDRSEGQLPFAAMGRVPPHSDAAVSRCQ
EWLADHYYEPNPVARMAALSGLPERTFKRRFKAATGYSPIDYVQALRIEEAKQMLETTGQPTDAVAHAVGYDDPAFFRRL
FKRSTGVTPARYRQRYRFIGLAAKDVV

Specific function: Regulatory protein for the mmsAB operon. Activates the transcription of the mmsAB genes [H]

COG id: COG4977

COG function: function code K; Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87082197, Length=102, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR003313
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF02311 AraC_binding; PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 37959; Mature: 37959

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDEIGPDTAARIQLLVVPETTPGTLYGLYELFDAVGVAWKDITGEAVNTPRLSPRIVSA
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEC
GGTAFASPIGIPIVPHDALSAAGRAEVVIVPDLSLTQDHDPRGRWAEEAAWLRRRFDDGA
CCCHHCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
VLCSVCTGSVLLAEAGLLEGVEATTHWGVTRLFSRYYPRVRLHAERILSPSGPEHRIVTC
EEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEEHHHHCCCCCCCCEEEEE
GGAGSWSDLALYLIARFCGPAEAVRLAKVFVLGDRSEGQLPFAAMGRVPPHSDAAVSRCQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHH
EWLADHYYEPNPVARMAALSGLPERTFKRRFKAATGYSPIDYVQALRIEEAKQMLETTGQ
HHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PTDAVAHAVGYDDPAFFRRLFKRSTGVTPARYRQRYRFIGLAAKDVV
CHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MRDEIGPDTAARIQLLVVPETTPGTLYGLYELFDAVGVAWKDITGEAVNTPRLSPRIVSA
CCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCHHHCCCCCCCCCCCCCCEEEEC
GGTAFASPIGIPIVPHDALSAAGRAEVVIVPDLSLTQDHDPRGRWAEEAAWLRRRFDDGA
CCCHHCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
VLCSVCTGSVLLAEAGLLEGVEATTHWGVTRLFSRYYPRVRLHAERILSPSGPEHRIVTC
EEHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHEEEHHHHCCCCCCCCEEEEE
GGAGSWSDLALYLIARFCGPAEAVRLAKVFVLGDRSEGQLPFAAMGRVPPHSDAAVSRCQ
CCCCCHHHHHHHHHHHHCCHHHHHHHHHEEEEECCCCCCCCHHHHCCCCCCCHHHHHHHH
EWLADHYYEPNPVARMAALSGLPERTFKRRFKAATGYSPIDYVQALRIEEAKQMLETTGQ
HHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
PTDAVAHAVGYDDPAFFRRLFKRSTGVTPARYRQRYRFIGLAAKDVV
CHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1339433; 10984043 [H]