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The map label for this gene is ald [H]

Identifier: 110633781

GI number: 110633781

Start: 1526257

End: 1527372

Strand: Reverse

Name: ald [H]

Synonym: Meso_1428

Alternate gene names: 110633781

Gene position: 1527372-1526257 (Counterclockwise)

Preceding gene: 110633784

Following gene: 110633778

Centisome position: 34.62

GC content: 62.28

Gene sequence:

>1116_bases
ATGCGTATCGGATGTCCCAAGGAAATCAAGAACCATGAATACCGGGTCGGCCTGACCCCGGGCTCGGTACGCGAATATAT
GGCCCACGGCCACGATGTGCTGGTCGAAACTGGCGCCGGTGCCGGGATCGGCGCGGATGACAATGCTTACCGAGCTGCGG
GCGCAGAAATCGCCAAATCGGCCGAAGACGTGTTTGCCCGGTCGGACATGATCGTAAAGGTGAAAGAGCCGCAGCCTTCG
GAATGGGTGCAACTTCGTGAAGGCCAGATCCTCTATACCTACCTCCACCTGGCTCCGGATCCTGAGCAAACCAAGGGCCT
GCTCGAAAGCGGCGTGACGGCGGTTGCTTACGAAACCGTGACGGACGCGCATGGCGGCCTGCCGTTGCTTGCCCCGATGT
CCGAAGTTGCCGGTCGCCTCGCGATCCAGGCGGGAGCTACGGCTCTGCAAAAGGCAAATGGCGGGCGCGGCGTGCTGCTT
GGGGGCGTGCCGGGTGTGCTGCCTGGCAAGGTCGCCATCATCGGCGGTGGAGTGGTCGGGCTTAATGCGGCAAAAATGGC
GGTGGGCCTCGGCGCCGACGTGACGATCATAGACCGGTCAATTCCACGGCTGCGCCAGCTGGATGACATCTTCAACGGGC
GCATCCACACGCGCTATTCCACTGTCGAAGCGATCGAAGAAGAGTGCTTTTCAGCCGATGTGGTGGTCGGCGCGGTGCTC
ATTCCGGGTGCCGCCGCGCCAAAGCTCGTCACCCGCGAGATGCTTTCCGGCATGAAGAAAGGTGCCATTTTGGTGGATGT
GGCGATCGATCAGGGCGGCTGCTTCGAGACCTCGCATGCCACCACCCATTCCGATCCGACCTATGAGGTGGACGGCATTA
TCCACTATTGCGTCGCGAACATGCCGGGTGCGGTGCCCGTCACCTCCGCGCATGCGCTCAACAACGCGACGCTGCACTAT
GGTTTGCAACTGGCCGGCAGGGGGCTAAGGGCTCTTGCGGACGACCAGCACCTGCGCAACGGCCTCAACGTGCATAAGGG
CCGCATCACGAACCGCGCGGTGGCGGATTCTCTCGGCTATGAAATGATCGAGCCAAAGGCCGCCCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
AATAACGAATTTGACCGGAGCGAGCAAATATATTCACAAGGACCTTCCAGCCGGTTTGTGGTTCCCTAGAGCAATTGAAC
AAAGCCAGTTGGAGGTGGCA

Downstream 100 bases:

>100_bases
TGCGCGCCGGCCTCCTTTGTGCGTCTTTTTTGACGCACAAAGCTGCTCGTAACCTGTCCGCCTGCTCGGGCGGACTTTGG
CCAAGAATTACGGGCGCAGC

Product: L-alanine dehydrogenase

Products: NA

Alternate protein names: Stage V sporulation protein N [H]

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MRIGCPKEIKNHEYRVGLTPGSVREYMAHGHDVLVETGAGAGIGADDNAYRAAGAEIAKSAEDVFARSDMIVKVKEPQPS
EWVQLREGQILYTYLHLAPDPEQTKGLLESGVTAVAYETVTDAHGGLPLLAPMSEVAGRLAIQAGATALQKANGGRGVLL
GGVPGVLPGKVAIIGGGVVGLNAAKMAVGLGADVTIIDRSIPRLRQLDDIFNGRIHTRYSTVEAIEEECFSADVVVGAVL
IPGAAAPKLVTREMLSGMKKGAILVDVAIDQGGCFETSHATTHSDPTYEVDGIIHYCVANMPGAVPVTSAHALNNATLHY
GLQLAGRGLRALADDQHLRNGLNVHKGRITNRAVADSLGYEMIEPKAALAA

Sequences:

>Translated_371_residues
MRIGCPKEIKNHEYRVGLTPGSVREYMAHGHDVLVETGAGAGIGADDNAYRAAGAEIAKSAEDVFARSDMIVKVKEPQPS
EWVQLREGQILYTYLHLAPDPEQTKGLLESGVTAVAYETVTDAHGGLPLLAPMSEVAGRLAIQAGATALQKANGGRGVLL
GGVPGVLPGKVAIIGGGVVGLNAAKMAVGLGADVTIIDRSIPRLRQLDDIFNGRIHTRYSTVEAIEEECFSADVVVGAVL
IPGAAAPKLVTREMLSGMKKGAILVDVAIDQGGCFETSHATTHSDPTYEVDGIIHYCVANMPGAVPVTSAHALNNATLHY
GLQLAGRGLRALADDQHLRNGLNVHKGRITNRAVADSLGYEMIEPKAALAA
>Mature_371_residues
MRIGCPKEIKNHEYRVGLTPGSVREYMAHGHDVLVETGAGAGIGADDNAYRAAGAEIAKSAEDVFARSDMIVKVKEPQPS
EWVQLREGQILYTYLHLAPDPEQTKGLLESGVTAVAYETVTDAHGGLPLLAPMSEVAGRLAIQAGATALQKANGGRGVLL
GGVPGVLPGKVAIIGGGVVGLNAAKMAVGLGADVTIIDRSIPRLRQLDDIFNGRIHTRYSTVEAIEEECFSADVVVGAVL
IPGAAAPKLVTREMLSGMKKGAILVDVAIDQGGCFETSHATTHSDPTYEVDGIIHYCVANMPGAVPVTSAHALNNATLHY
GLQLAGRGLRALADDQHLRNGLNVHKGRITNRAVADSLGYEMIEPKAALAA

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=344, Percent_Identity=30.8139534883721, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI122939153, Length=344, Percent_Identity=30.8139534883721, Blast_Score=137, Evalue=2e-32,
Organism=Escherichia coli, GI1787887, Length=334, Percent_Identity=32.9341317365269, Blast_Score=134, Evalue=7e-33,
Organism=Caenorhabditis elegans, GI17550456, Length=382, Percent_Identity=28.7958115183246, Blast_Score=127, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 38853; Mature: 38853

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIGCPKEIKNHEYRVGLTPGSVREYMAHGHDVLVETGAGAGIGADDNAYRAAGAEIAKS
CCCCCCHHHCCCCEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
AEDVFARSDMIVKVKEPQPSEWVQLREGQILYTYLHLAPDPEQTKGLLESGVTAVAYETV
HHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCEEEEEEHH
TDAHGGLPLLAPMSEVAGRLAIQAGATALQKANGGRGVLLGGVPGVLPGKVAIIGGGVVG
HCCCCCCCCCCCHHHHHHHEEHHHCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCEEC
LNAAKMAVGLGADVTIIDRSIPRLRQLDDIFNGRIHTRYSTVEAIEEECFSADVVVGAVL
CCHHHHHEECCCCEEEECCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHEEHEE
IPGAAAPKLVTREMLSGMKKGAILVDVAIDQGGCFETSHATTHSDPTYEVDGIIHYCVAN
ECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCCEEHHHHHHHHHHC
MPGAVPVTSAHALNNATLHYGLQLAGRGLRALADDQHLRNGLNVHKGRITNRAVADSLGY
CCCCCCCCCHHHCCCCEEEECHHHHCCCHHHHCCHHHHHCCCCCCCCCCCHHHHHHHCCH
EMIEPKAALAA
HHCCCHHHHCC
>Mature Secondary Structure
MRIGCPKEIKNHEYRVGLTPGSVREYMAHGHDVLVETGAGAGIGADDNAYRAAGAEIAKS
CCCCCCHHHCCCCEEEECCCHHHHHHHHCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHH
AEDVFARSDMIVKVKEPQPSEWVQLREGQILYTYLHLAPDPEQTKGLLESGVTAVAYETV
HHHHHHCCCEEEEECCCCCHHHHHCCCCCEEEEEEEECCCHHHHHHHHHCCCEEEEEEHH
TDAHGGLPLLAPMSEVAGRLAIQAGATALQKANGGRGVLLGGVPGVLPGKVAIIGGGVVG
HCCCCCCCCCCCHHHHHHHEEHHHCHHHHHHCCCCCEEEECCCCCCCCCCEEEEECCEEC
LNAAKMAVGLGADVTIIDRSIPRLRQLDDIFNGRIHTRYSTVEAIEEECFSADVVVGAVL
CCHHHHHEECCCCEEEECCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHEEHEE
IPGAAAPKLVTREMLSGMKKGAILVDVAIDQGGCFETSHATTHSDPTYEVDGIIHYCVAN
ECCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCEECCCCCCCCCCCEEHHHHHHHHHHC
MPGAVPVTSAHALNNATLHYGLQLAGRGLRALADDQHLRNGLNVHKGRITNRAVADSLGY
CCCCCCCCCHHHCCCCEEEECHHHHCCCHHHHCCHHHHHCCCCCCCCCCCHHHHHHHCCH
EMIEPKAALAA
HHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226620; 9384377 [H]