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The map label for this gene is putA [H]

Identifier: 110633678

GI number: 110633678

Start: 1415470

End: 1419084

Strand: Direct

Name: putA [H]

Synonym: Meso_1325

Alternate gene names: 110633678

Gene position: 1415470-1419084 (Clockwise)

Preceding gene: 110633676

Following gene: 110633681

Centisome position: 32.08

GC content: 66.36

Gene sequence:

>3615_bases
ATGCCTGCACTCGATGCCCTTCGCGACGAGATCCGGAAACATTACCTTGCCGATGAAGACGTTCTGCTCCGGCGGCTGAT
CGAATCCGCCGACCTCTCCCCCGCCCGTCGTGAGGCGATTTCGGCAAAGGCGGCGGAACTGGTGCGCGCGGTGCGGGCAG
GCTCCACCCGGCATTTGATGGAATCCTTCCTGGCGGAGTACGGCCTATCGACCAGCGAGGGCGTAGCGCTGATGTGCCTG
GCGGAGGCGCTGCTGCGCGTCCCTGATGCGGAGACCATGGATGACCTCATCGCCGACAAGATCGCGCCGCACGATTGGTC
GGCGCATTCGGGCGAATCCGCCTCCATCTTCGTGAACGCCTCCACCTGGGCGCTGATGCTGACGGGCCGTGTGCTGGACG
ATGAAGGCAACGGCATCGAGGCGACGCTGCGCGGCATGGTCCGCCGCCTGGGCGAGCCGGTGATCCGCGCCGCGGTGGCC
GCCGCCATGCGCGAAATGGGCGAGCAGTTCGTGCTTGGCCGCACCATCGCGGAGGCGATCAAGCGCGGCCGTGCGATGAC
CGCCAAGGGCTATACCTATTCCTATGACATGCTGGGCGAGGCAGCCCGCACGGAAGCCGATGCCCGGCGCTATTTCCAGG
CTTACCGGAATGCGATCGCCGCGCTTAAGGGAGAGGCGAAGAGCGAGGATATCCGCGCCAATCCAGGCATTTCCGTAAAG
CTGTCGGCAATCCACCCCCGTTACGAGGCCACGCAGCGCGAACGCGTGATGCCGGTCGTGACCGAACGCCTGCTTCTGCT
TGCGCAGGACGCCAGGGCCGCGCGCATGGGCCTCAACATCGACGCGGAGGAAGCGGACCGGCTCGACCTCTCGCTTGACG
TGATCGAGCGCGTGCTGGCGGACCCCTCGCTTGAAGGTTGGGACGGCTTCGGCATTGTCGTCCAGGCCTATGGGCGGCGT
GCCCCCTTTGTCATCGACTGGCTTTACGCGCTTGCCGAAAGGCTTGACCGCCGGATCATGGTCCGTCTCGTGAAGGGAGC
CTATTGGGACACGGAGATCAAGCGTGCGCAGGTCATGGGCCTGTCGAGCTATCCCGTCTTCACGCGCAAGGTGAACACGG
ACATCTCCTATATTGCCTGCGCGCGGAAGCTCCTTTCGTTGACCGATCGCATCTACCCGCAATTCGCCACGCACAACGCG
CACACGGTCGCCGCCATCCTGGCCATGGCCGAGAACAGGAATGCTTTCGAATTCCAGCGTCTGCACGGGATGGGCGAGGC
CCTGCACGATATCATTAAGCGCCGCGAAGGAACGCGCTGCCGCATCTATGCGCCCGTGGGCGCGCATGAGGATTTGCTTG
CCTATCTGGTCCGCCGCCTTCTCGAAAACGGCGCCAATTCTTCCTTCGTCCACCAGATCGTGGATGAAGAGGTGAGCGCG
GAGGAGATCGCGCGTGATCCCTTCGCCCTGGCCGAAGCCGCCGGCTCTGCTCCGAATCCGGCCATTCCCCTGCCGGCACT
CATCTTCGGTCGGCAGCGGATTAACGCGAAGGGGTGGGACATCACCGACGAGACGGCGCTTCGTGAGATCGAGACGGCGC
GGCGGCCTTTCCAGGCGCCGCATCGCTGGGAAGGGCGGCCGATCACGCGCGCGAGAGGGCAGGGCGAGGCGCGCATCATC
GTCAATCCCGCCCGGACCAGCGAAATCGTCGGCACGGTTTTTGATGCTTCGCCCGGGCAGGTGAGCGAATCGGTCCGCCT
TGCGGTTGCCGCCCAGCCCGGCTGGGCCGCCACGCCGGTTACCGAGAGGGCGGAGATCCTGCGGCGCATCGCCGATCTCT
ACGAAGCCCATGCCGGCGAATTCTTCGCCCTTTGCGCGCGAGAGGCGGGCAAGACATTGCCTGACGGCATTGCCGAACTG
CGCGAGGCCGTGGATTTCCTGCGCTATTATGCAAACGAGGCGGCACAGGCGGAGGAGGGGACCGGGGCGCGTGGCGTCAT
CGCCTGCATCTCGCCCTGGAACTTCCCGCTCGCCATCTTCACGGGCCAGATCGCGGCGGCGCTTGTGACGGGCAATGCGG
TGGTGGCCAAGCCCGCGGAGCAGACCTGCCTCATAGCAACGCGTGCGGTGGCGCTGATGCACGAAGCGGGCGTCCCCGAA
GATGTGCTGCATCTCCTGCCCGGCGACGGCCCCTCCGTCGGCGCGCCGCTCACGGCGGACCCGCGCATCGCCGGCGTCTG
TTTCACGGGCTCGACCGAGGTTGCGCGGGCGATCGAGCGCCAGCTTGCCAAGACCGCCGCGCCTGACGCGATGCTGATTG
CCGAAACCGGCGGCCTCAACGCCATGATCGTCGATTCCACGGCCCTGCCGGAACAGGCCGTGCGCGACATCCTCGCCTCT
GCCTTCCAGAGCGCCGGCCAGCGCTGTTCCGCCTTGCGAATCCTTTACATCCAGAAGGATGTGGAGGCCCGTGTGACCGC
GATGCTTCGAGGAGCCATGCAGGCGCTCACCGTAGGTGATCCTTGGCAGGTTCCCACCGATGTGGGCCCCGTCATCGATG
ACGAGGCCCTTTCCGGGATTTCCGGCTATTGCGAGGAGATGGAGCGCAAGGGCCGTCTCCTCGCCCGGATCGAGCGGCCC
GAGGGGGGGCGCTTCGTGGCGCCCGCAGCCTTCCAAGTCTCGGGCATCGAGGAAATGGAGCGTGAGGTTTTCGGCCCCGT
CCTGCATGTTGCCACCTTCGAGGCGGAGGATCTGGGACACGTGATTTCCGCAGTCAACGCGAAGGGTTACGGCCTGACTT
TCGGGCTTCACACGCGAATTGACGCGCGCGTGCAGGAGGTCGTGGACGGGATCCATGCCGGCAACATCTATGTTAACCGC
AACCAGATCGGAGCGGTCGTGGGATCGCAGCCTTTCGGCGGAGAAGGGCTTTCGGGCACCGGGCCAAAGGCGGGCGGTCC
GCATTATCTACGGCGTTTCCGCCGCGGCAAGGCCGGGCCGGACCTCGCGCCAGCCGATGCTCCGGCGATCGCCGCCGAAG
AGCTGGTGCGGGCAATGCCCGATGCGCAAAAGAGCGGCTGGGCGGATCGCACAGATCGCATCGTCGCGCTGCGGCGCGCG
CTGCGCGGGCGCTGGGCGGACGTGCTTGCCTCCGCGGCCGCCCTCGATCTGGGTCCTGTCGACCTGCCCGGGCCTACGGG
CGAGGCCAACACCCTGCAGCTTGCCCCACGCGGCCGCGTGCTTTGCCTTGGCGCCGATGCCGATGCTCTTGCCGCGCAGG
TGATCCAGGCGCTTGCCGCGGGCAATGCGGTGCTTGCCGTCGCAAAAGATGCGCCGGCCATCTTGCAGCCCCTGACCAGG
GCCGGATTTCCGCTCGCCGCTTTCCATGGAAATGTCGCGCCGCAGACACTGGAAACACTCGCGCTCGATCTTGTTGCGGC
TACGGGGGAGCGGCAGTGGCTCACGGCAGTGAGGACCGCGCTTTCCGCGCGGGAAGGCCGGATCGTGCCGCTCGTGACGG
AGCTTGTCTACCCCGCGGCCTATGCCCATGAGCGATCGGTCTGCGTCGACACGACGGCGGCGGGTGGAAATGCAAGCCTG
CTTGCAGCGGCTTAA

Upstream 100 bases:

>100_bases
GAACAGTATTTATGATCTTACAAACGCTAGATTTCAGTCCGGCGGGCGTCTGCACCATATGATAAGAACGTCGAAGTCCT
ACGCTGATCGAGGTCCTCCG

Downstream 100 bases:

>100_bases
CCGACGCTAGCCGTCGAGCCTCATGAAAGCGCCGGGCTCCTCCGGGTATGGAGTTTTGCCTCCGCCCCGCCGCTTCCACG
CCTTCCGGCGACCGGCGCCG

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1204; Mature: 1203

Protein sequence:

>1204_residues
MPALDALRDEIRKHYLADEDVLLRRLIESADLSPARREAISAKAAELVRAVRAGSTRHLMESFLAEYGLSTSEGVALMCL
AEALLRVPDAETMDDLIADKIAPHDWSAHSGESASIFVNASTWALMLTGRVLDDEGNGIEATLRGMVRRLGEPVIRAAVA
AAMREMGEQFVLGRTIAEAIKRGRAMTAKGYTYSYDMLGEAARTEADARRYFQAYRNAIAALKGEAKSEDIRANPGISVK
LSAIHPRYEATQRERVMPVVTERLLLLAQDARAARMGLNIDAEEADRLDLSLDVIERVLADPSLEGWDGFGIVVQAYGRR
APFVIDWLYALAERLDRRIMVRLVKGAYWDTEIKRAQVMGLSSYPVFTRKVNTDISYIACARKLLSLTDRIYPQFATHNA
HTVAAILAMAENRNAFEFQRLHGMGEALHDIIKRREGTRCRIYAPVGAHEDLLAYLVRRLLENGANSSFVHQIVDEEVSA
EEIARDPFALAEAAGSAPNPAIPLPALIFGRQRINAKGWDITDETALREIETARRPFQAPHRWEGRPITRARGQGEARII
VNPARTSEIVGTVFDASPGQVSESVRLAVAAQPGWAATPVTERAEILRRIADLYEAHAGEFFALCAREAGKTLPDGIAEL
REAVDFLRYYANEAAQAEEGTGARGVIACISPWNFPLAIFTGQIAAALVTGNAVVAKPAEQTCLIATRAVALMHEAGVPE
DVLHLLPGDGPSVGAPLTADPRIAGVCFTGSTEVARAIERQLAKTAAPDAMLIAETGGLNAMIVDSTALPEQAVRDILAS
AFQSAGQRCSALRILYIQKDVEARVTAMLRGAMQALTVGDPWQVPTDVGPVIDDEALSGISGYCEEMERKGRLLARIERP
EGGRFVAPAAFQVSGIEEMEREVFGPVLHVATFEAEDLGHVISAVNAKGYGLTFGLHTRIDARVQEVVDGIHAGNIYVNR
NQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRRGKAGPDLAPADAPAIAAEELVRAMPDAQKSGWADRTDRIVALRRA
LRGRWADVLASAAALDLGPVDLPGPTGEANTLQLAPRGRVLCLGADADALAAQVIQALAAGNAVLAVAKDAPAILQPLTR
AGFPLAAFHGNVAPQTLETLALDLVAATGERQWLTAVRTALSAREGRIVPLVTELVYPAAYAHERSVCVDTTAAGGNASL
LAAA

Sequences:

>Translated_1204_residues
MPALDALRDEIRKHYLADEDVLLRRLIESADLSPARREAISAKAAELVRAVRAGSTRHLMESFLAEYGLSTSEGVALMCL
AEALLRVPDAETMDDLIADKIAPHDWSAHSGESASIFVNASTWALMLTGRVLDDEGNGIEATLRGMVRRLGEPVIRAAVA
AAMREMGEQFVLGRTIAEAIKRGRAMTAKGYTYSYDMLGEAARTEADARRYFQAYRNAIAALKGEAKSEDIRANPGISVK
LSAIHPRYEATQRERVMPVVTERLLLLAQDARAARMGLNIDAEEADRLDLSLDVIERVLADPSLEGWDGFGIVVQAYGRR
APFVIDWLYALAERLDRRIMVRLVKGAYWDTEIKRAQVMGLSSYPVFTRKVNTDISYIACARKLLSLTDRIYPQFATHNA
HTVAAILAMAENRNAFEFQRLHGMGEALHDIIKRREGTRCRIYAPVGAHEDLLAYLVRRLLENGANSSFVHQIVDEEVSA
EEIARDPFALAEAAGSAPNPAIPLPALIFGRQRINAKGWDITDETALREIETARRPFQAPHRWEGRPITRARGQGEARII
VNPARTSEIVGTVFDASPGQVSESVRLAVAAQPGWAATPVTERAEILRRIADLYEAHAGEFFALCAREAGKTLPDGIAEL
REAVDFLRYYANEAAQAEEGTGARGVIACISPWNFPLAIFTGQIAAALVTGNAVVAKPAEQTCLIATRAVALMHEAGVPE
DVLHLLPGDGPSVGAPLTADPRIAGVCFTGSTEVARAIERQLAKTAAPDAMLIAETGGLNAMIVDSTALPEQAVRDILAS
AFQSAGQRCSALRILYIQKDVEARVTAMLRGAMQALTVGDPWQVPTDVGPVIDDEALSGISGYCEEMERKGRLLARIERP
EGGRFVAPAAFQVSGIEEMEREVFGPVLHVATFEAEDLGHVISAVNAKGYGLTFGLHTRIDARVQEVVDGIHAGNIYVNR
NQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRRGKAGPDLAPADAPAIAAEELVRAMPDAQKSGWADRTDRIVALRRA
LRGRWADVLASAAALDLGPVDLPGPTGEANTLQLAPRGRVLCLGADADALAAQVIQALAAGNAVLAVAKDAPAILQPLTR
AGFPLAAFHGNVAPQTLETLALDLVAATGERQWLTAVRTALSAREGRIVPLVTELVYPAAYAHERSVCVDTTAAGGNASL
LAAA
>Mature_1203_residues
PALDALRDEIRKHYLADEDVLLRRLIESADLSPARREAISAKAAELVRAVRAGSTRHLMESFLAEYGLSTSEGVALMCLA
EALLRVPDAETMDDLIADKIAPHDWSAHSGESASIFVNASTWALMLTGRVLDDEGNGIEATLRGMVRRLGEPVIRAAVAA
AMREMGEQFVLGRTIAEAIKRGRAMTAKGYTYSYDMLGEAARTEADARRYFQAYRNAIAALKGEAKSEDIRANPGISVKL
SAIHPRYEATQRERVMPVVTERLLLLAQDARAARMGLNIDAEEADRLDLSLDVIERVLADPSLEGWDGFGIVVQAYGRRA
PFVIDWLYALAERLDRRIMVRLVKGAYWDTEIKRAQVMGLSSYPVFTRKVNTDISYIACARKLLSLTDRIYPQFATHNAH
TVAAILAMAENRNAFEFQRLHGMGEALHDIIKRREGTRCRIYAPVGAHEDLLAYLVRRLLENGANSSFVHQIVDEEVSAE
EIARDPFALAEAAGSAPNPAIPLPALIFGRQRINAKGWDITDETALREIETARRPFQAPHRWEGRPITRARGQGEARIIV
NPARTSEIVGTVFDASPGQVSESVRLAVAAQPGWAATPVTERAEILRRIADLYEAHAGEFFALCAREAGKTLPDGIAELR
EAVDFLRYYANEAAQAEEGTGARGVIACISPWNFPLAIFTGQIAAALVTGNAVVAKPAEQTCLIATRAVALMHEAGVPED
VLHLLPGDGPSVGAPLTADPRIAGVCFTGSTEVARAIERQLAKTAAPDAMLIAETGGLNAMIVDSTALPEQAVRDILASA
FQSAGQRCSALRILYIQKDVEARVTAMLRGAMQALTVGDPWQVPTDVGPVIDDEALSGISGYCEEMERKGRLLARIERPE
GGRFVAPAAFQVSGIEEMEREVFGPVLHVATFEAEDLGHVISAVNAKGYGLTFGLHTRIDARVQEVVDGIHAGNIYVNRN
QIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRRGKAGPDLAPADAPAIAAEELVRAMPDAQKSGWADRTDRIVALRRAL
RGRWADVLASAAALDLGPVDLPGPTGEANTLQLAPRGRVLCLGADADALAAQVIQALAAGNAVLAVAKDAPAILQPLTRA
GFPLAAFHGNVAPQTLETLALDLVAATGERQWLTAVRTALSAREGRIVPLVTELVYPAAYAHERSVCVDTTAAGGNASLL
AAA

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777736, Length=464, Percent_Identity=30.3879310344828, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI25777734, Length=464, Percent_Identity=30.3879310344828, Blast_Score=184, Evalue=5e-46,
Organism=Homo sapiens, GI238859541, Length=464, Percent_Identity=30.3879310344828, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI153266822, Length=455, Percent_Identity=30.1098901098901, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI21614513, Length=499, Percent_Identity=28.8577154308617, Blast_Score=170, Evalue=8e-42,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.8724832214765, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777730, Length=452, Percent_Identity=31.858407079646, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=30.5309734513274, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI238814322, Length=417, Percent_Identity=28.2973621103118, Blast_Score=163, Evalue=9e-40,
Organism=Homo sapiens, GI21361176, Length=453, Percent_Identity=31.3465783664459, Blast_Score=163, Evalue=1e-39,
Organism=Homo sapiens, GI12007648, Length=456, Percent_Identity=27.6315789473684, Blast_Score=157, Evalue=6e-38,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=30.6372549019608, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI188035924, Length=471, Percent_Identity=28.2377919320594, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI310128103, Length=471, Percent_Identity=28.2377919320594, Blast_Score=147, Evalue=6e-35,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=28.4164859002169, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI115387104, Length=443, Percent_Identity=27.765237020316, Blast_Score=139, Evalue=2e-32,
Organism=Homo sapiens, GI4507229, Length=421, Percent_Identity=28.5035629453682, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI25952152, Length=444, Percent_Identity=26.8018018018018, Blast_Score=129, Evalue=2e-29,
Organism=Homo sapiens, GI25777721, Length=434, Percent_Identity=27.6497695852535, Blast_Score=126, Evalue=2e-28,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=27.7777777777778, Blast_Score=120, Evalue=6e-27,
Organism=Homo sapiens, GI25777726, Length=452, Percent_Identity=26.5486725663717, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=25.4117647058824, Blast_Score=112, Evalue=2e-24,
Organism=Homo sapiens, GI310128089, Length=335, Percent_Identity=26.865671641791, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI310128087, Length=285, Percent_Identity=28.4210526315789, Blast_Score=95, Evalue=5e-19,
Organism=Homo sapiens, GI301500698, Length=442, Percent_Identity=22.8506787330317, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI71773324, Length=387, Percent_Identity=24.5478036175711, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI4502043, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI238814371, Length=321, Percent_Identity=24.9221183800623, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI310128095, Length=312, Percent_Identity=27.8846153846154, Blast_Score=92, Evalue=3e-18,
Organism=Homo sapiens, GI206597441, Length=329, Percent_Identity=24.3161094224924, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI206597439, Length=329, Percent_Identity=24.3161094224924, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI22907049, Length=329, Percent_Identity=24.3161094224924, Blast_Score=88, Evalue=4e-17,
Organism=Homo sapiens, GI310128097, Length=259, Percent_Identity=28.957528957529, Blast_Score=85, Evalue=5e-16,
Organism=Homo sapiens, GI73695881, Length=319, Percent_Identity=23.5109717868339, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI73695879, Length=319, Percent_Identity=23.5109717868339, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI310128101, Length=224, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI310128099, Length=224, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=8e-15,
Organism=Homo sapiens, GI73466520, Length=324, Percent_Identity=21.9135802469136, Blast_Score=76, Evalue=2e-13,
Organism=Homo sapiens, GI4557303, Length=324, Percent_Identity=21.9135802469136, Blast_Score=76, Evalue=2e-13,
Organism=Escherichia coli, GI1787250, Length=1227, Percent_Identity=47.0252648736756, Blast_Score=979, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=463, Percent_Identity=31.7494600431965, Blast_Score=175, Evalue=2e-44,
Organism=Escherichia coli, GI1787684, Length=479, Percent_Identity=31.3152400835073, Blast_Score=170, Evalue=5e-43,
Organism=Escherichia coli, GI1788042, Length=446, Percent_Identity=31.390134529148, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI87081896, Length=483, Percent_Identity=30.4347826086957, Blast_Score=168, Evalue=2e-42,
Organism=Escherichia coli, GI1787715, Length=452, Percent_Identity=32.0796460176991, Blast_Score=162, Evalue=2e-40,
Organism=Escherichia coli, GI1787558, Length=423, Percent_Identity=31.2056737588652, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI1786504, Length=448, Percent_Identity=29.2410714285714, Blast_Score=147, Evalue=4e-36,
Organism=Escherichia coli, GI87082295, Length=418, Percent_Identity=28.2296650717703, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87081926, Length=440, Percent_Identity=27.2727272727273, Blast_Score=115, Evalue=2e-26,
Organism=Escherichia coli, GI1787653, Length=403, Percent_Identity=23.8213399503722, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17534447, Length=490, Percent_Identity=30.4081632653061, Blast_Score=179, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI133930964, Length=552, Percent_Identity=27.7173913043478, Blast_Score=166, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI115532534, Length=381, Percent_Identity=30.9711286089239, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25143874, Length=450, Percent_Identity=29.3333333333333, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25143876, Length=450, Percent_Identity=29.3333333333333, Blast_Score=157, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17562198, Length=452, Percent_Identity=29.4247787610619, Blast_Score=156, Evalue=8e-38,
Organism=Caenorhabditis elegans, GI71995606, Length=450, Percent_Identity=28.2222222222222, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI115534176, Length=437, Percent_Identity=30.6636155606407, Blast_Score=148, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25144435, Length=455, Percent_Identity=28.7912087912088, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32564736, Length=406, Percent_Identity=29.8029556650246, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17551164, Length=450, Percent_Identity=27.5555555555556, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71995613, Length=408, Percent_Identity=27.9411764705882, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI32564151, Length=426, Percent_Identity=28.4037558685446, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=424, Percent_Identity=26.6509433962264, Blast_Score=127, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17534119, Length=453, Percent_Identity=26.4900662251656, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71990744, Length=283, Percent_Identity=30.7420494699647, Blast_Score=111, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=366, Percent_Identity=25.9562841530055, Blast_Score=103, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI32566756, Length=366, Percent_Identity=25.9562841530055, Blast_Score=103, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI25146394, Length=366, Percent_Identity=25.9562841530055, Blast_Score=103, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17564084, Length=326, Percent_Identity=26.9938650306748, Blast_Score=96, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=454, Percent_Identity=33.4801762114537, Blast_Score=189, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=29.3333333333333, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6321826, Length=479, Percent_Identity=27.7661795407098, Blast_Score=160, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6325196, Length=415, Percent_Identity=29.6385542168675, Blast_Score=159, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6323822, Length=454, Percent_Identity=29.5154185022026, Blast_Score=155, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6323821, Length=453, Percent_Identity=29.8013245033113, Blast_Score=151, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6319478, Length=456, Percent_Identity=26.9736842105263, Blast_Score=135, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6321828, Length=467, Percent_Identity=25.9100642398287, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24668425, Length=469, Percent_Identity=29.637526652452, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24668417, Length=469, Percent_Identity=29.637526652452, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24668413, Length=469, Percent_Identity=29.637526652452, Blast_Score=189, Evalue=1e-47,
Organism=Drosophila melanogaster, GI20129399, Length=447, Percent_Identity=30.6487695749441, Blast_Score=166, Evalue=9e-41,
Organism=Drosophila melanogaster, GI24650465, Length=460, Percent_Identity=29.3478260869565, Blast_Score=162, Evalue=1e-39,
Organism=Drosophila melanogaster, GI281362580, Length=451, Percent_Identity=27.7161862527716, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI62472918, Length=451, Percent_Identity=27.7161862527716, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI62472926, Length=451, Percent_Identity=27.7161862527716, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI62472936, Length=451, Percent_Identity=27.7161862527716, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI21356737, Length=451, Percent_Identity=27.7161862527716, Blast_Score=152, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24585660, Length=452, Percent_Identity=26.1061946902655, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI28571802, Length=440, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571800, Length=440, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571806, Length=440, Percent_Identity=27.2727272727273, Blast_Score=142, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571798, Length=440, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571796, Length=440, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28571794, Length=440, Percent_Identity=27.2727272727273, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI24666674, Length=511, Percent_Identity=26.614481409002, Blast_Score=133, Evalue=9e-31,
Organism=Drosophila melanogaster, GI28574525, Length=474, Percent_Identity=24.0506329113924, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24638878, Length=424, Percent_Identity=26.8867924528302, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24638876, Length=424, Percent_Identity=26.8867924528302, Blast_Score=108, Evalue=3e-23,
Organism=Drosophila melanogaster, GI281360299, Length=347, Percent_Identity=27.9538904899135, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281360297, Length=347, Percent_Identity=27.9538904899135, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281360295, Length=347, Percent_Identity=27.9538904899135, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI24586250, Length=347, Percent_Identity=27.9538904899135, Blast_Score=106, Evalue=9e-23,
Organism=Drosophila melanogaster, GI281360301, Length=347, Percent_Identity=27.9538904899135, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45552499, Length=346, Percent_Identity=26.878612716763, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360303, Length=346, Percent_Identity=26.878612716763, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 129440; Mature: 129309

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPALDALRDEIRKHYLADEDVLLRRLIESADLSPARREAISAKAAELVRAVRAGSTRHLM
CCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
ESFLAEYGLSTSEGVALMCLAEALLRVPDAETMDDLIADKIAPHDWSAHSGESASIFVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEC
STWALMLTGRVLDDEGNGIEATLRGMVRRLGEPVIRAAVAAAMREMGEQFVLGRTIAEAI
CEEEEEEECEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRGRAMTAKGYTYSYDMLGEAARTEADARRYFQAYRNAIAALKGEAKSEDIRANPGISVK
HCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LSAIHPRYEATQRERVMPVVTERLLLLAQDARAARMGLNIDAEEADRLDLSLDVIERVLA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHC
DPSLEGWDGFGIVVQAYGRRAPFVIDWLYALAERLDRRIMVRLVKGAYWDTEIKRAQVMG
CCCCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
LSSYPVFTRKVNTDISYIACARKLLSLTDRIYPQFATHNAHTVAAILAMAENRNAFEFQR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCHHHHHH
LHGMGEALHDIIKRREGTRCRIYAPVGAHEDLLAYLVRRLLENGANSSFVHQIVDEEVSA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
EEIARDPFALAEAAGSAPNPAIPLPALIFGRQRINAKGWDITDETALREIETARRPFQAP
HHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
HRWEGRPITRARGQGEARIIVNPARTSEIVGTVFDASPGQVSESVRLAVAAQPGWAATPV
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCCCH
TERAEILRRIADLYEAHAGEFFALCAREAGKTLPDGIAELREAVDFLRYYANEAAQAEEG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGARGVIACISPWNFPLAIFTGQIAAALVTGNAVVAKPAEQTCLIATRAVALMHEAGVPE
CCCCEEEEEECCCCCCHHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHCCCCH
DVLHLLPGDGPSVGAPLTADPRIAGVCFTGSTEVARAIERQLAKTAAPDAMLIAETGGLN
HHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCE
AMIVDSTALPEQAVRDILASAFQSAGQRCSALRILYIQKDVEARVTAMLRGAMQALTVGD
EEEECCCCCCHHHHHHHHHHHHHHHCCHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCC
PWQVPTDVGPVIDDEALSGISGYCEEMERKGRLLARIERPEGGRFVAPAAFQVSGIEEME
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHCCHHHHH
REVFGPVLHVATFEAEDLGHVISAVNAKGYGLTFGLHTRIDARVQEVVDGIHAGNIYVNR
HHHHHHHHHHEECCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEC
NQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRRGKAGPDLAPADAPAIAAEELVRAMP
CHHCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
DAQKSGWADRTDRIVALRRALRGRWADVLASAAALDLGPVDLPGPTGEANTLQLAPRGRV
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCE
LCLGADADALAAQVIQALAAGNAVLAVAKDAPAILQPLTRAGFPLAAFHGNVAPQTLETL
EEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEECCCCCCHHHHHHH
ALDLVAATGERQWLTAVRTALSAREGRIVPLVTELVYPAAYAHERSVCVDTTAAGGNASL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
LAAA
EEEC
>Mature Secondary Structure 
PALDALRDEIRKHYLADEDVLLRRLIESADLSPARREAISAKAAELVRAVRAGSTRHLM
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHH
ESFLAEYGLSTSEGVALMCLAEALLRVPDAETMDDLIADKIAPHDWSAHSGESASIFVNA
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEEEC
STWALMLTGRVLDDEGNGIEATLRGMVRRLGEPVIRAAVAAAMREMGEQFVLGRTIAEAI
CEEEEEEECEEECCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KRGRAMTAKGYTYSYDMLGEAARTEADARRYFQAYRNAIAALKGEAKSEDIRANPGISVK
HCCCCEEECCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEE
LSAIHPRYEATQRERVMPVVTERLLLLAQDARAARMGLNIDAEEADRLDLSLDVIERVLA
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCHHHHHHHHC
DPSLEGWDGFGIVVQAYGRRAPFVIDWLYALAERLDRRIMVRLVKGAYWDTEIKRAQVMG
CCCCCCCCCCCHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCC
LSSYPVFTRKVNTDISYIACARKLLSLTDRIYPQFATHNAHTVAAILAMAENRNAFEFQR
CCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCHHHHCCCHHHHHHHHHHHCCCCHHHHHH
LHGMGEALHDIIKRREGTRCRIYAPVGAHEDLLAYLVRRLLENGANSSFVHQIVDEEVSA
HHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCH
EEIARDPFALAEAAGSAPNPAIPLPALIFGRQRINAKGWDITDETALREIETARRPFQAP
HHHHCCCHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCC
HRWEGRPITRARGQGEARIIVNPARTSEIVGTVFDASPGQVSESVRLAVAAQPGWAATPV
CCCCCCCCCCCCCCCCEEEEECCCCHHHHHHEEECCCCCCCCCCEEEEEEECCCCCCCCH
TERAEILRRIADLYEAHAGEFFALCAREAGKTLPDGIAELREAVDFLRYYANEAAQAEEG
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
TGARGVIACISPWNFPLAIFTGQIAAALVTGNAVVAKPAEQTCLIATRAVALMHEAGVPE
CCCCEEEEEECCCCCCHHHHHHHHHHHHEECCEEEECCCCHHHHHHHHHHHHHHHCCCCH
DVLHLLPGDGPSVGAPLTADPRIAGVCFTGSTEVARAIERQLAKTAAPDAMLIAETGGLN
HHHHHCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEEEECCCCE
AMIVDSTALPEQAVRDILASAFQSAGQRCSALRILYIQKDVEARVTAMLRGAMQALTVGD
EEEECCCCCCHHHHHHHHHHHHHHHCCHHHHEEEEEEECCHHHHHHHHHHHHHHHHCCCC
PWQVPTDVGPVIDDEALSGISGYCEEMERKGRLLARIERPEGGRFVAPAAFQVSGIEEME
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCEECCCHHHHCCHHHHH
REVFGPVLHVATFEAEDLGHVISAVNAKGYGLTFGLHTRIDARVQEVVDGIHAGNIYVNR
HHHHHHHHHHEECCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHCCCCCCCEEEEC
NQIGAVVGSQPFGGEGLSGTGPKAGGPHYLRRFRRGKAGPDLAPADAPAIAAEELVRAMP
CHHCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCC
DAQKSGWADRTDRIVALRRALRGRWADVLASAAALDLGPVDLPGPTGEANTLQLAPRGRV
CCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEECCCCCE
LCLGADADALAAQVIQALAAGNAVLAVAKDAPAILQPLTRAGFPLAAFHGNVAPQTLETL
EEEECCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCEEECCCCCCHHHHHHH
ALDLVAATGERQWLTAVRTALSAREGRIVPLVTELVYPAAYAHERSVCVDTTAAGGNASL
HHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCEE
LAAA
EEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]